HK17577A - Clathrate prostaglandins and compositions containing same - Google Patents
Clathrate prostaglandins and compositions containing sameInfo
- Publication number
- HK17577A HK17577A HK175/77A HK17577A HK17577A HK 17577 A HK17577 A HK 17577A HK 175/77 A HK175/77 A HK 175/77A HK 17577 A HK17577 A HK 17577A HK 17577 A HK17577 A HK 17577A
- Authority
- HK
- Hong Kong
- Prior art keywords
- clathrate
- prostaglandins
- compositions containing
- containing same
- same
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title 1
- 229940094443 oxytocics prostaglandins Drugs 0.000 title 1
- 150000003180 prostaglandins Chemical class 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
- C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
- C08B37/0015—Inclusion compounds, i.e. host-guest compounds, e.g. polyrotaxanes
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nanotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Polymers & Plastics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Materials Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medical Informatics (AREA)
- Biophysics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP45050119A JPS503362B1 (fi) | 1970-06-10 | 1970-06-10 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK17577A true HK17577A (en) | 1977-04-22 |
Family
ID=12850213
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK175/77A HK17577A (en) | 1970-06-10 | 1977-04-14 | Clathrate prostaglandins and compositions containing same |
Country Status (22)
Country | Link |
---|---|
US (1) | US3816393A (fi) |
JP (1) | JPS503362B1 (fi) |
AT (1) | AT332570B (fi) |
BE (1) | BE768288A (fi) |
CA (1) | CA958007A (fi) |
CH (1) | CH568259A5 (fi) |
CS (1) | CS170169B2 (fi) |
CY (1) | CY895A (fi) |
DE (1) | DE2128674C2 (fi) |
DK (1) | DK140837B (fi) |
ES (1) | ES392074A1 (fi) |
FR (1) | FR2100745B1 (fi) |
GB (1) | GB1351238A (fi) |
HK (1) | HK17577A (fi) |
HU (1) | HU163135B (fi) |
IE (1) | IE35326B1 (fi) |
NL (1) | NL162901C (fi) |
NO (1) | NO134373C (fi) |
RO (1) | RO62182A (fi) |
SE (1) | SE390818B (fi) |
SU (1) | SU404225A3 (fi) |
ZA (1) | ZA713398B (fi) |
Families Citing this family (79)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4163108A (en) * | 1967-02-16 | 1979-07-31 | Lever Brothers Company | Prostaglandins |
US4054736A (en) * | 1970-06-10 | 1977-10-18 | Ono Pharmaceutical Co., Ltd. | Clathrate compounds of prostaglandins or their analogues with cyclodextrin |
CA984387A (en) * | 1971-04-12 | 1976-02-24 | Barney J. Magerlein | Analogs of prostaglandins |
US3954833A (en) * | 1971-04-12 | 1976-05-04 | The Upjohn Company | 16,16-Methyl and ethyl substituted PGF2.sub.α compounds |
US3903131A (en) * | 1971-04-12 | 1975-09-02 | Upjohn Co | 16 and 16,16-dimethyl PGE{HD 2{B |
FR2134673A1 (en) * | 1971-04-30 | 1972-12-08 | Ono Pharmaceutical Co | Novel optically active isomers of prostaglandin analoguesof natural configuration useful as hypotensive agents, diuretics,contraceptives, for treating gastric ulcer and asthma, and forinhibiting platelet aggregation |
US4045467A (en) * | 1972-02-18 | 1977-08-30 | May & Baker Limited | Cyclopentane derivatives |
US4082789A (en) * | 1972-03-28 | 1978-04-04 | The University Court Of The University Of Edinburgh | Prostaglandins C2 |
JPS4926258A (fi) * | 1972-07-06 | 1974-03-08 | ||
US4110368A (en) * | 1972-07-24 | 1978-08-29 | American Cyanamid Company | Hydro substituted prostanoic acids and esters |
US4130721A (en) * | 1972-07-24 | 1978-12-19 | The Upjohn Company | 11-Deoxy PGE2 compounds |
US4141914A (en) * | 1972-07-24 | 1979-02-27 | American Cyanamid Company | Novel 11-deoxy-11-substituted prostaglandins of the E and F series |
JPS4942648A (fi) * | 1972-08-24 | 1974-04-22 | ||
US3962312A (en) * | 1972-09-21 | 1976-06-08 | Ono Pharmaceutical Company | 9,11,15-Trihydroxy prost-5-enoic acid analogues |
US3972917A (en) * | 1972-10-27 | 1976-08-03 | American Home Products Corporation | 11-Deoxy 15-methyl prostaglandin E1 |
JPS5443570B2 (fi) * | 1972-10-27 | 1979-12-20 | ||
US4092427A (en) * | 1973-04-16 | 1978-05-30 | American Home Products Corporation | Method of inducing abortion using alkyl derivatives of prostanoic acids |
JPS5623984B2 (fi) * | 1973-04-19 | 1981-06-03 | ||
US4246426A (en) * | 1973-08-06 | 1981-01-20 | Hoffmann-La Roche Inc. | 11-Substituted prostaglandins |
US4052446A (en) * | 1973-08-06 | 1977-10-04 | Hoffmann-La Roche Inc. | 11,16-substituted prostaglandins |
US4059576A (en) * | 1973-08-06 | 1977-11-22 | Hoffmann-La Roche, Inc. | 11-Substituted prostaglandins |
US4026927A (en) * | 1973-09-25 | 1977-05-31 | Yamanouchi Pharmaceutical Co., Ltd. | Novel prostaglandin derivatives |
US4036954A (en) * | 1973-11-02 | 1977-07-19 | Yamanouchi Pharmaceutical Co., Ltd. | Stable prostaglandin E group-containing formulation |
GB1448268A (en) * | 1973-11-13 | 1976-09-02 | May & Baker Ltd | Cyclopentane derivatives |
US4041066A (en) * | 1974-02-07 | 1977-08-09 | The Upjohn Company | 4,5-Cis-didehydro-PGE1 compounds |
GB1441564A (en) * | 1974-02-07 | 1976-07-07 | Upjohn Co | Prostaglandins |
DE2416193C2 (de) * | 1974-04-03 | 1985-08-14 | Hoechst Ag, 6230 Frankfurt | Prostaglandin-Analoge, Verfahren zu ihrer Herstellung sowie ihre Verwendung als cytoprotektives Mittel |
US3974195A (en) * | 1974-10-02 | 1976-08-10 | The Upjohn Company | 2A,2B-Dihomo-15-alkyl-PGF2.sub.α analogs |
US4256651A (en) * | 1974-10-02 | 1981-03-17 | The Upjohn Company | 2a,2b-Dihomo-15-alkyl-PGF1β compounds |
GB1482010A (en) * | 1974-10-28 | 1977-08-03 | Ono Pharmaceutical Co | Prostaglandin analogues |
DK142235B (da) * | 1974-12-20 | 1980-09-29 | Yamanouchi Pharma Co Ltd | Analogifremgangsmåde til fremstilling af 20-alkoxy-16-methyl-prostadiensyre-derivater. |
US4207420A (en) * | 1975-02-24 | 1980-06-10 | The Upjohn Company | 2,2-Difluoro-PGF1 analogs |
US4209637A (en) * | 1975-02-24 | 1980-06-24 | The Upjohn Company | 2,2-Difluoro-PGF2 analogs |
US4059701A (en) * | 1975-04-17 | 1977-11-22 | American Home Products Corporation | 15-Substituted prostanoic acids for treating bronchial spasm |
FR2313019A2 (fr) * | 1975-06-04 | 1976-12-31 | Ono Pharmaceutical Co | Nouveaux analogues de prostaglandines et leur procede de preparation |
US4086269A (en) * | 1975-07-07 | 1978-04-25 | American Home Products Corporation | 11-Deoxy-15-substituted prostaglandins |
US4026909A (en) * | 1975-07-14 | 1977-05-31 | The Upjohn Company | Cis-13-PGF2.sub.α analogs |
US4033989A (en) * | 1975-09-17 | 1977-07-05 | The Upjohn Company | 9-Deoxy-PGF2 Analogs |
US4016184A (en) * | 1975-09-17 | 1977-04-05 | The Upjohn Company | 9-Deoxy-9,10-didehydro-PGD1 compounds |
US4013695A (en) * | 1975-10-02 | 1977-03-22 | The Upjohn Company | 4,4,5,5-Tetradehydro-PGE1 analogs |
US4053500A (en) * | 1975-10-02 | 1977-10-11 | The Upjohn Company | 4,4,5,5-Tetradehydro-ω-aryl-PGF1α analogs |
US4053502A (en) * | 1975-10-02 | 1977-10-11 | The Upjohn Company | 4,4,5,5-Tetradehydro-ω-aryl-PGE1 analogs |
US4026919A (en) * | 1975-10-23 | 1977-05-31 | The Upjohn Company | PGD2 Substituted esters |
US4058665A (en) * | 1975-11-06 | 1977-11-15 | Yamanouchi Pharmaceutical Co., Ltd. | Novel 3,15-dilower alkyl PGE2 derivatives |
US4212987A (en) * | 1976-09-17 | 1980-07-15 | The Upjohn Company | 2,2-Difluoro-PGE1 analogs |
US4212986A (en) * | 1976-09-17 | 1980-07-15 | The Upjohn Company | 2,2-Difluoro-PGE2 analogs |
US4169895A (en) * | 1976-09-28 | 1979-10-02 | Pfizer Inc. | Antisecretory 16,16-dimethyl-17-oxaprostaglandins |
JPS53136513A (en) * | 1977-05-06 | 1978-11-29 | Ono Pharmaceut Co Ltd | Stabilization of prostaglandin-x-related compounds |
HU179141B (fi) * | 1977-09-23 | 1982-08-28 | ||
JPS5577440U (fi) * | 1978-11-25 | 1980-05-28 | ||
US4244883A (en) * | 1979-09-12 | 1981-01-13 | The Upjohn Company | 2a,2b-Dihomo-15-alkyl-PGF2β compounds |
ZA831186B (en) * | 1982-03-22 | 1983-11-30 | Upjohn Ltd | Gelled pge2/triacetin solutions |
DE3504044A1 (de) * | 1985-02-04 | 1986-08-07 | Schering AG, Berlin und Bergkamen, 1000 Berlin | 9-halogenprostaglandin-clathrate und ihre verwendung als arzneimittel |
DE3608088C2 (de) * | 1986-03-07 | 1995-11-16 | Schering Ag | Pharmazeutische Präparate, enthaltend Cyclodextrinclathrate von Carbacyclinderivaten |
DE3740838A1 (de) * | 1987-11-27 | 1989-06-08 | Schering Ag | Cyclodextrinclathrate von 5-cyano-prostacyclinderivaten und ihre verwendung als arzneimittel |
US5221695A (en) * | 1987-12-22 | 1993-06-22 | Glaxo Group Limited | Aqueous formulation containing a piperidinylcyclopentylheptenoic acid derivative and beta-cyclodextrin |
HU204700B (en) * | 1987-12-22 | 1992-02-28 | Glaxo Group Ltd | Process for producing aqueous compositions comprising piperidinyl cyclopentylheptenoic acid derivatives |
KR0166088B1 (ko) * | 1990-01-23 | 1999-01-15 | . | 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도 |
US5376645A (en) * | 1990-01-23 | 1994-12-27 | University Of Kansas | Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof |
US5874418A (en) * | 1997-05-05 | 1999-02-23 | Cydex, Inc. | Sulfoalkyl ether cyclodextrin based solid pharmaceutical formulations and their use |
DE19828881A1 (de) * | 1998-06-22 | 1999-12-23 | Schering Ag | Oxidationsinhibitor bei Prostan-Derivaten |
US6287603B1 (en) | 1999-09-16 | 2001-09-11 | Nestec S.A. | Cyclodextrin flavor delivery systems |
PT1417975E (pt) | 2001-07-23 | 2011-05-30 | Ono Pharmaceutical Co | Medicamentos que cont?m um agonista de ep4 como princ?pio activo destinados a doen?as associadas a perda de massa ?ssea |
ES2393321T3 (es) | 2002-10-10 | 2012-12-20 | Ono Pharmaceutical Co., Ltd. | Promotores de la producción de factores de reparación endógenos |
EP2422814A1 (en) | 2003-07-25 | 2012-02-29 | Ono Pharmaceutical Co., Ltd. | Remedy for cartilage-related diseases |
CN100542537C (zh) * | 2004-07-27 | 2009-09-23 | 中国人民解放军军事医学科学院毒物药物研究所 | 前列腺素e1口腔制剂 |
RU2008101420A (ru) * | 2005-06-13 | 2009-07-20 | Карджилл, Инкорпорейтед (Us) | Циклодекстриновые комплексы включения и способы их получения |
AU2006259877A1 (en) * | 2005-06-13 | 2006-12-28 | Cargill, Incorporated | Cyclodextrin inclusion complexes and methods of preparing same |
US20090185985A1 (en) * | 2006-06-13 | 2009-07-23 | Cargill, Incorporated | Large-particle cyclodextrin inclusion complexes and methods of preparing same |
WO2008083213A2 (en) * | 2006-12-27 | 2008-07-10 | Cargill, Incorporated | Stabilisation by preparing cyclodextrin inclusion complexes |
BRPI0807942A2 (pt) | 2007-02-16 | 2014-07-01 | Ono Pharmaceutical Co | Agente terapêutico para distúrbio de excreção urinária |
CN101686985A (zh) | 2007-05-08 | 2010-03-31 | 国立大学法人浜松医科大学 | 含有ep4激动剂的细胞毒性t细胞的活化剂 |
US20080283693A1 (en) * | 2007-05-15 | 2008-11-20 | Evans Michael J F | Propulsion apparatus and system |
PT2441760E (pt) | 2009-06-10 | 2014-01-07 | Ono Pharmaceutical Co | Composto com actividade de contracção muscular do detrusor e actividade de relaxação muscular do esfíncter uretral |
JP4890657B1 (ja) * | 2011-06-03 | 2012-03-07 | 小野薬品工業株式会社 | リマプロストとβ−シクロデキストリンを含有する錠剤 |
US9682065B2 (en) | 2011-08-02 | 2017-06-20 | Ono Pharmaceutical Co., Ltd. | Left ventricular diastolic function improving agent |
WO2014034902A1 (ja) | 2012-08-31 | 2014-03-06 | 小野薬品工業株式会社 | アミン塩とその結晶 |
KR102532836B1 (ko) | 2016-05-09 | 2023-05-15 | 에이지씨 가부시키가이샤 | 신규 프로스타글란딘 유도체 |
EP4403542A1 (en) * | 2021-09-13 | 2024-07-24 | FUJIFILM Corporation | Production method for encapsulation of bicycloalkane compound |
-
1970
- 1970-06-10 JP JP45050119A patent/JPS503362B1/ja active Pending
-
1971
- 1971-05-26 US US00147255A patent/US3816393A/en not_active Expired - Lifetime
- 1971-05-26 ZA ZA713398A patent/ZA713398B/xx unknown
- 1971-06-03 AT AT480371A patent/AT332570B/de not_active IP Right Cessation
- 1971-06-04 CH CH813871A patent/CH568259A5/xx not_active IP Right Cessation
- 1971-06-07 RO RO67198A patent/RO62182A/ro unknown
- 1971-06-08 NO NO2171/71A patent/NO134373C/no unknown
- 1971-06-09 DE DE2128674A patent/DE2128674C2/de not_active Expired
- 1971-06-09 DK DK279771AA patent/DK140837B/da not_active IP Right Cessation
- 1971-06-09 NL NL7107894.A patent/NL162901C/xx not_active IP Right Cessation
- 1971-06-09 SE SE7107486A patent/SE390818B/xx unknown
- 1971-06-09 SU SU1668708A patent/SU404225A3/ru active
- 1971-06-09 ES ES392074A patent/ES392074A1/es not_active Expired
- 1971-06-09 IE IE710/71A patent/IE35326B1/xx unknown
- 1971-06-09 CY CY895A patent/CY895A/xx unknown
- 1971-06-09 GB GB1978571*[A patent/GB1351238A/en not_active Expired
- 1971-06-09 BE BE768288A patent/BE768288A/xx not_active IP Right Cessation
- 1971-06-10 FR FR7121129A patent/FR2100745B1/fr not_active Expired
- 1971-06-10 CA CA115,284A patent/CA958007A/en not_active Expired
- 1971-06-10 HU HUOO173A patent/HU163135B/hu not_active IP Right Cessation
- 1971-06-10 CS CS4254A patent/CS170169B2/cs unknown
-
1977
- 1977-04-14 HK HK175/77A patent/HK17577A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
NL7107894A (fi) | 1971-12-14 |
SE390818B (sv) | 1977-01-24 |
FR2100745B1 (fi) | 1974-08-30 |
HU163135B (fi) | 1973-06-28 |
NO134373B (fi) | 1976-06-21 |
ZA713398B (en) | 1972-01-26 |
DK140837C (fi) | 1981-09-07 |
NO134373C (fi) | 1976-09-29 |
NL162901C (nl) | 1980-07-15 |
FR2100745A1 (fi) | 1972-03-24 |
CS170169B2 (fi) | 1976-08-27 |
IE35326L (en) | 1971-12-10 |
CY895A (en) | 1977-10-07 |
SU404225A3 (fi) | 1973-10-26 |
CH568259A5 (fi) | 1975-10-31 |
CA958007A (en) | 1974-11-19 |
DE2128674C2 (de) | 1982-06-24 |
ES392074A1 (es) | 1974-08-01 |
BE768288A (fr) | 1971-11-03 |
AT332570B (de) | 1976-10-11 |
US3816393A (en) | 1974-06-11 |
NL162901B (nl) | 1980-02-15 |
DE2128674A1 (de) | 1971-12-16 |
JPS503362B1 (fi) | 1975-02-04 |
RO62182A (fi) | 1977-07-15 |
ATA480371A (de) | 1976-01-15 |
IE35326B1 (en) | 1976-01-07 |
DK140837B (da) | 1979-11-26 |
GB1351238A (en) | 1974-04-24 |
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