HK1258517A1 - 靶向psca的嵌合抗原受體 - Google Patents
靶向psca的嵌合抗原受體Info
- Publication number
- HK1258517A1 HK1258517A1 HK19100869.7A HK19100869A HK1258517A1 HK 1258517 A1 HK1258517 A1 HK 1258517A1 HK 19100869 A HK19100869 A HK 19100869A HK 1258517 A1 HK1258517 A1 HK 1258517A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- psca
- chimeric antigen
- antigen receptors
- receptors targeted
- targeted
- Prior art date
Links
- 108010019670 Chimeric Antigen Receptors Proteins 0.000 title 1
Classifications
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- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
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US201562238062P | 2015-10-06 | 2015-10-06 | |
PCT/US2016/055761 WO2017062628A1 (en) | 2015-10-06 | 2016-10-06 | Chimeric antigen receptors targeted to psca |
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HK19100869.7A HK1258517A1 (zh) | 2015-10-06 | 2019-01-17 | 靶向psca的嵌合抗原受體 |
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JP7178355B2 (ja) | 2017-02-28 | 2022-11-25 | エンドサイト・インコーポレイテッド | Car t細胞療法のための組成物および方法 |
CN109306013B (zh) * | 2017-07-26 | 2020-09-25 | 重庆精准生物技术有限公司 | 抗cd20抗原的嵌合抗原受体及其应用 |
US11311576B2 (en) | 2018-01-22 | 2022-04-26 | Seattle Children's Hospital | Methods of use for CAR T cells |
WO2020004337A1 (ja) * | 2018-06-27 | 2020-01-02 | 国立大学法人名古屋大学 | Cd37特異的キメラ抗原レセプター |
US20230065784A1 (en) | 2019-03-21 | 2023-03-02 | City Of Hope | Composition and method for reducing expression of checkpoint inhibitors in t cells expressing a car or ctl |
CN114729059A (zh) * | 2019-09-11 | 2022-07-08 | 宾夕法尼亚大学董事会 | 包含前列腺干细胞抗原(psca)嵌合抗原受体(cars)的组合物和方法 |
CN111097043B (zh) * | 2020-01-13 | 2023-07-04 | 广东昭泰体内生物医药科技有限公司 | 一种胃癌药物组合物及其应用 |
CA3199876A1 (en) * | 2020-11-24 | 2022-06-02 | Jianhua Yu | Compositions and uses of psca targeted chimeric antigen receptor modified cells |
KR20230124656A (ko) | 2020-12-24 | 2023-08-25 | 카이트 파마 인코포레이티드 | 전립선암 키메라 항원 수용체 |
WO2022212525A2 (en) | 2021-03-30 | 2022-10-06 | City Of Hope | Car t cell therapy and ifn gamma |
WO2023173116A1 (en) | 2022-03-10 | 2023-09-14 | City Of Hope | Membrane-bound il-12 for cellular immunotherapy |
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WO2005000898A2 (en) | 2003-06-27 | 2005-01-06 | Biogen Idec Ma Inc. | Use of hydrophobic-interaction-chromatography or hinge-region modifications for the production of homogeneous antibody-solutions |
MXPA06013834A (es) | 2004-05-28 | 2007-03-01 | Agensys Inc | Anticuerpos y moleculas relacionadas que enlazan a proteinas psca. |
WO2009032949A2 (en) * | 2007-09-04 | 2009-03-12 | The Regents Of The University Of California | High affinity anti-prostate stem cell antigen (psca) antibodies for cancer targeting and detection |
SG190997A1 (en) * | 2010-12-09 | 2013-07-31 | Univ Pennsylvania | Use of chimeric antigen receptor-modified t cells to treat cancer |
RU2700765C2 (ru) | 2012-08-20 | 2019-09-19 | Фред Хатчинсон Кансэр Рисёч Сентер | Способ и композиции для клеточной иммунотерапии |
US9657105B2 (en) * | 2013-03-15 | 2017-05-23 | City Of Hope | CD123-specific chimeric antigen receptor redirected T cells and methods of their use |
US10144770B2 (en) * | 2013-10-17 | 2018-12-04 | National University Of Singapore | Chimeric receptors and uses thereof in immune therapy |
BR112016009898A2 (pt) * | 2013-10-31 | 2017-12-05 | Hutchinson Fred Cancer Res | células-tronco/progenitoras hematopoiéticas e efetoras não-t modificadas e usos das mesmas |
CA2936501A1 (en) | 2014-01-13 | 2015-07-16 | Stephen J. Forman | Chimeric antigen receptors (cars) having mutations in the fc spacer region and methods for their use |
CN106132423B (zh) | 2014-02-14 | 2020-07-31 | 贝里坤制药股份有限公司 | 用诱导型嵌合多肽活化t细胞的方法 |
IL297591A (en) * | 2014-04-10 | 2022-12-01 | Seattle Childrens Hospital Dba Seattle Childrens Res Inst | Drug-related transgene expression |
SG10201913625XA (en) * | 2015-08-07 | 2020-03-30 | Imaginab Inc | Antigen binding constructs to target molecules |
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US11466097B2 (en) | 2022-10-11 |
ES2809550T3 (es) | 2021-03-04 |
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EP3359574B1 (en) | 2020-04-22 |
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JP2018530333A (ja) | 2018-10-18 |
CN108290956A (zh) | 2018-07-17 |
RU2021132734A (ru) | 2022-04-25 |
KR20180056770A (ko) | 2018-05-29 |
JP2022043056A (ja) | 2022-03-15 |
MX2018004289A (es) | 2018-06-19 |
US20230348617A1 (en) | 2023-11-02 |
US20200308300A1 (en) | 2020-10-01 |
AU2016336515A1 (en) | 2018-04-26 |
JP6985256B2 (ja) | 2021-12-22 |
AU2016336515B2 (en) | 2023-08-24 |
IL258502B1 (en) | 2023-01-01 |
JP7297854B2 (ja) | 2023-06-26 |
EP3747462A1 (en) | 2020-12-09 |
RU2018113510A3 (zh) | 2020-03-17 |
CN108290956B (zh) | 2022-07-05 |
CN115074331B (zh) | 2024-05-17 |
EP3359574A1 (en) | 2018-08-15 |
IL258502B2 (en) | 2023-05-01 |
RU2759879C2 (ru) | 2021-11-18 |
CN115074331A (zh) | 2022-09-20 |
WO2017062628A1 (en) | 2017-04-13 |
CA3001230A1 (en) | 2017-04-13 |
BR112018006991A2 (pt) | 2018-10-16 |
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