HK1256907A1 - 測序技術中的脫靶捕捉降低 - Google Patents
測序技術中的脫靶捕捉降低Info
- Publication number
- HK1256907A1 HK1256907A1 HK18116018.4A HK18116018A HK1256907A1 HK 1256907 A1 HK1256907 A1 HK 1256907A1 HK 18116018 A HK18116018 A HK 18116018A HK 1256907 A1 HK1256907 A1 HK 1256907A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- target capture
- sequencing techniques
- reduction
- capture reduction
- sequencing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
- C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
- C12Q2537/159—Reduction of complexity, e.g. amplification of subsets, removing duplicated genomic regions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
- C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
- C12Q2537/163—Reactions characterised by the reaction format or use of a specific feature the purpose or use of blocking probe
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/131—Nucleic acid detection characterized by the use of physical, structural and functional properties the label being a member of a cognate binding pair, i.e. extends to antibodies, haptens, avidin
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562238411P | 2015-10-07 | 2015-10-07 | |
| US15/286,374 US10577643B2 (en) | 2015-10-07 | 2016-10-05 | Off-target capture reduction in sequencing techniques |
| PCT/US2016/055736 WO2017062613A1 (en) | 2015-10-07 | 2016-10-06 | Off-target capture reduction in sequencing techniques |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1256907A1 true HK1256907A1 (zh) | 2019-10-04 |
Family
ID=57184842
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK18116018.4A HK1256907A1 (zh) | 2015-10-07 | 2018-12-13 | 測序技術中的脫靶捕捉降低 |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US10577643B2 (zh) |
| EP (2) | EP3940083A1 (zh) |
| JP (1) | JP6761467B2 (zh) |
| KR (3) | KR102295723B1 (zh) |
| CN (1) | CN108474032A (zh) |
| HK (1) | HK1256907A1 (zh) |
| WO (1) | WO2017062613A1 (zh) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012142213A2 (en) | 2011-04-15 | 2012-10-18 | The Johns Hopkins University | Safe sequencing system |
| EP3447495B2 (en) | 2012-10-29 | 2024-03-13 | The Johns Hopkins University | Papanicolaou test for ovarian and endometrial cancers |
| US11286531B2 (en) | 2015-08-11 | 2022-03-29 | The Johns Hopkins University | Assaying ovarian cyst fluid |
| US10577645B2 (en) * | 2016-03-18 | 2020-03-03 | Norgen Biotek Corp. | Methods and kits for improving global gene expression analysis of human blood, plasma and/or serum derived RNA |
| MX2020001575A (es) | 2017-08-07 | 2020-11-18 | Univ Johns Hopkins | Materiales y métodos para evaluar y tratar el cáncer. |
| JP7344786B2 (ja) * | 2019-12-19 | 2023-09-14 | 株式会社日立製作所 | 溶液中の任意のｄｎａ配列を同定する方法 |
| CN116323963A (zh) * | 2020-05-11 | 2023-06-23 | 私人基因诊断公司 | 选择性捕获靶dna序列 |
| CN111961711A (zh) * | 2020-08-31 | 2020-11-20 | 伯科生物科技有限公司 | 用于靶向测序的通用杂交增强剂及方法 |
| CN117730155A (zh) * | 2021-05-24 | 2024-03-19 | 豪夫迈·罗氏有限公司 | 用于核酸杂交的增强子寡核苷酸 |
| CN113981041B (zh) * | 2021-11-25 | 2024-04-30 | 首都医科大学附属北京安贞医院 | 靶向富集测序试剂及靶向富集方法 |
| CN115101128B (zh) * | 2022-06-29 | 2023-09-15 | 纳昂达(南京)生物科技有限公司 | 一种杂交捕获探针脱靶危险性评估的方法 |
| CN116230086B (zh) * | 2022-12-26 | 2023-11-10 | 纳昂达(南京)生物科技有限公司 | 一种通过修改模体提升探针安全性的方法及装置 |
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| US5846719A (en) | 1994-10-13 | 1998-12-08 | Lynx Therapeutics, Inc. | Oligonucleotide tags for sorting and identification |
| US5750341A (en) | 1995-04-17 | 1998-05-12 | Lynx Therapeutics, Inc. | DNA sequencing by parallel oligonucleotide extensions |
| ATE545710T1 (de) | 1997-04-01 | 2012-03-15 | Illumina Cambridge Ltd | Verfahren zur vervielfältigung von nukleinsäuren |
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| GB9713597D0 (en) * | 1997-06-28 | 1997-09-03 | Sec Dep Of The Home Department | Improvements in and relating to forensic identification |
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| US7001792B2 (en) | 2000-04-24 | 2006-02-21 | Eagle Research & Development, Llc | Ultra-fast nucleic acid sequencing device and a method for making and using the same |
| AU2002310441A1 (en) * | 2001-06-14 | 2003-01-02 | The Regents Of The University Of California | A novel signaling pathway for the production of inflammatory pain and neuropathy |
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| JP4515767B2 (ja) * | 2002-01-31 | 2010-08-04 | ユニバーシティ・オブ・ユタ | 非標的核酸依存性増幅の低減：反復核酸配列の増幅 |
| US20030148288A1 (en) * | 2002-02-01 | 2003-08-07 | Yi-Wei Tang | Colorimetric genetic test for clinically significant TNF polymorphism and methods of use thereof |
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| CN104004854A (zh) | 2014-06-18 | 2014-08-27 | 天津市秀鹏生物技术开发有限公司 | 用于检测人类红细胞abo血型基因分型的引物组及试剂盒 |
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-
2016
- 2016-10-05 US US15/286,374 patent/US10577643B2/en active Active
- 2016-10-06 KR KR1020187012973A patent/KR102295723B1/ko active IP Right Grant
- 2016-10-06 EP EP21188310.3A patent/EP3940083A1/en active Pending
- 2016-10-06 JP JP2018517837A patent/JP6761467B2/ja active Active
- 2016-10-06 CN CN201680068374.4A patent/CN108474032A/zh active Pending
- 2016-10-06 KR KR1020217026816A patent/KR102416944B1/ko active IP Right Grant
- 2016-10-06 KR KR1020227022402A patent/KR20220094220A/ko active IP Right Grant
- 2016-10-06 WO PCT/US2016/055736 patent/WO2017062613A1/en active Application Filing
- 2016-10-06 EP EP16784662.5A patent/EP3359687B1/en active Active
-
2018
- 2018-12-13 HK HK18116018.4A patent/HK1256907A1/zh unknown
-
2020
- 2020-02-05 US US16/782,833 patent/US11624084B2/en active Active
-
2023
- 2023-02-06 US US18/165,153 patent/US20230193357A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| KR102416944B1 (ko) | 2022-07-05 |
| US20170101676A1 (en) | 2017-04-13 |
| US20200172960A1 (en) | 2020-06-04 |
| US10577643B2 (en) | 2020-03-03 |
| KR20210107175A (ko) | 2021-08-31 |
| KR20180063300A (ko) | 2018-06-11 |
| CN108474032A (zh) | 2018-08-31 |
| WO2017062613A1 (en) | 2017-04-13 |
| JP6761467B2 (ja) | 2020-09-23 |
| KR20220094220A (ko) | 2022-07-05 |
| EP3359687B1 (en) | 2021-11-03 |
| US20230193357A1 (en) | 2023-06-22 |
| EP3940083A1 (en) | 2022-01-19 |
| US11624084B2 (en) | 2023-04-11 |
| EP3359687A1 (en) | 2018-08-15 |
| KR102295723B1 (ko) | 2021-08-30 |
| JP2018529371A (ja) | 2018-10-11 |
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