HK1255210A1 - 用於改進聚合物囊泡中功能性蛋白質的包封的組合物和方法 - Google Patents

用於改進聚合物囊泡中功能性蛋白質的包封的組合物和方法

Info

Publication number
HK1255210A1
HK1255210A1 HK18114338.2A HK18114338A HK1255210A1 HK 1255210 A1 HK1255210 A1 HK 1255210A1 HK 18114338 A HK18114338 A HK 18114338A HK 1255210 A1 HK1255210 A1 HK 1255210A1
Authority
HK
Hong Kong
Prior art keywords
compositions
methods
functional proteins
polymeric vesicles
improved encapsulation
Prior art date
Application number
HK18114338.2A
Other languages
English (en)
Inventor
P Peter Ghoroghchian
Jivan Namdeo Yewle
Original Assignee
Poseida Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Poseida Therapeutics Inc filed Critical Poseida Therapeutics Inc
Publication of HK1255210A1 publication Critical patent/HK1255210A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/41—Porphyrin- or corrin-ring-containing peptides
    • A61K38/42—Haemoglobins; Myoglobins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1273—Polymersomes; Liposomes with polymerisable or polymerised bilayer-forming substances

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Dispersion Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Preparation (AREA)
  • Inorganic Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
HK18114338.2A 2015-07-02 2018-11-09 用於改進聚合物囊泡中功能性蛋白質的包封的組合物和方法 HK1255210A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562187942P 2015-07-02 2015-07-02
US15/198,836 US10456452B2 (en) 2015-07-02 2016-06-30 Compositions and methods for improved encapsulation of functional proteins in polymeric vesicles
PCT/US2016/040657 WO2017004498A1 (en) 2015-07-02 2016-07-01 Compositions and methods for improved encapsulation of functional proteins in polymeric vesicles

Publications (1)

Publication Number Publication Date
HK1255210A1 true HK1255210A1 (zh) 2019-08-09

Family

ID=57609207

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18114338.2A HK1255210A1 (zh) 2015-07-02 2018-11-09 用於改進聚合物囊泡中功能性蛋白質的包封的組合物和方法

Country Status (8)

Country Link
US (2) US10456452B2 (zh)
EP (1) EP3316861B1 (zh)
JP (1) JP6840750B2 (zh)
CN (1) CN108348467B (zh)
AU (1) AU2016287579B2 (zh)
CA (1) CA2991101C (zh)
HK (1) HK1255210A1 (zh)
WO (1) WO2017004498A1 (zh)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10456452B2 (en) 2015-07-02 2019-10-29 Poseida Therapeutics, Inc. Compositions and methods for improved encapsulation of functional proteins in polymeric vesicles
WO2017190091A1 (en) 2016-04-29 2017-11-02 Vindico Nanobiotechnology, Llc Poly(histidine)-based micelles for complexation and delivery of proteins and nucleic acids
KR102588469B1 (ko) 2016-09-30 2023-10-11 포세이다 테라퓨틱스, 인크. 변형된 줄기세포 기억 t 세포, 이의 제조 방법 및 사용 방법
US20190119636A1 (en) 2017-10-23 2019-04-25 Poseida Therapeutics, Inc. Modified stem cell memory t cells, methods of making and methods of using same
MX2019003983A (es) 2016-10-06 2019-06-10 Poseida Therapeutics Inc Caspasas inducibles y metodos de uso.
US10329543B2 (en) 2017-10-23 2019-06-25 Poseida Therapeutics, Inc. Modified stem cell memory T cells, methods of making and methods of using same
US20220042038A1 (en) 2018-12-20 2022-02-10 Poseida Therapeutics, Inc. Nanotransposon compositions and methods of use
EP3739321B1 (de) * 2019-05-17 2023-03-08 Xtal Concepts GmbH Qualifizierungsverfahren für kryoelektronenmikroskopie-proben sowie dazugehöriger probenhalter
AU2020342544A1 (en) 2019-09-05 2022-03-24 Poseida Therapeutics, Inc. Allogeneic cell compositions and methods of use
WO2021127505A1 (en) 2019-12-20 2021-06-24 Poseida Therapeutics, Inc. Anti-muc1 compositions and methods of use
WO2021183795A1 (en) 2020-03-11 2021-09-16 Poseida Therapeutics, Inc. Chimeric stimulatory receptors and methods of use in t cell activation and differentiation
EP4298205A1 (en) 2021-02-23 2024-01-03 Poseida Therapeutics, Inc. Genetically modified induced pluripotent stem cells and methods of use thereof
CN113264997B (zh) * 2021-04-13 2023-07-04 康汉医药(广州)有限公司 一种蛋白药物在常温、高温条件下保存的方法
CA3233506A1 (en) 2021-10-04 2023-04-13 Joseph S. LUCAS Transposon compositions and methods of use thereof
WO2023164573A1 (en) 2022-02-23 2023-08-31 Poseida Therapeutics, Inc. Genetically modified cells and methods of use thereof
CN115710581A (zh) * 2022-11-16 2023-02-24 哈尔滨工业大学 一种提高酶利用率的蛋白质囊泡聚集体的构建方法

Family Cites Families (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5227170A (en) 1989-06-22 1993-07-13 Vestar, Inc. Encapsulation process
US5256422A (en) 1991-03-28 1993-10-26 Micro Vesicular Systems, Inc. Lipid vesicle containing water-in-oil emulsions
US5612310A (en) 1993-05-24 1997-03-18 Duke University Methods for improving therapeutic effectiveness of agents for the treatment of solid tumors and other disorders
US5595756A (en) 1993-12-22 1997-01-21 Inex Pharmaceuticals Corporation Liposomal compositions for enhanced retention of bioactive agents
US5833974A (en) 1996-04-17 1998-11-10 Teicher; Beverly A. Method of enhancing the effective life of oxygen-delivery agents
GB9624540D0 (en) 1996-11-26 1997-01-15 Nycomed Imaging As Compositions
EP1096950B1 (en) 1998-07-10 2003-09-10 Duke University Therapies using hemoproteins
CA2348781A1 (en) 1998-11-12 2000-05-25 Novolytics Inc. Compositions and methods for producing vascular occlusion
US20080181939A1 (en) 1999-12-14 2008-07-31 Trustees Of The University Of Pennsylvania Polymersomes and related encapsulating membranes
US6835394B1 (en) 1999-12-14 2004-12-28 The Trustees Of The University Of Pennsylvania Polymersomes and related encapsulating membranes
ES2232613T3 (es) 2000-04-26 2005-06-01 Cellegy Pharmaceuticals, Inc Formulaciones y metodos de utilizacion de agentes mimeticos del oxido nitrico contra un fenotipo celular maligno.
US6376525B1 (en) 2000-09-15 2002-04-23 Qingzhong Kong Method and composition for treating cancer using cellular organelle crystallizing agents
US20020115216A1 (en) 2000-05-19 2002-08-22 Steer Clifford J. Composition for delivery of compounds to cells
DE10031741A1 (de) 2000-06-29 2002-01-17 Sanguibio Tech Ag Einen Sauerstoffträger, ausgewählt aus Hämoglobin oder Hämoglobin- und Myoglobin-enthaltende Zubereitung als Externum zur natürlichen Regeneration der Haut bei Sauerstoff-Mangel
IL160799A0 (en) 2001-09-12 2004-08-31 Virexx Medical Corp Vascular occlusion solid-phase agent with immobilised platelet binding agent
US20030153491A1 (en) 2002-01-11 2003-08-14 Winslow Robert M. Methods and compositions for oxygen transport comprising a high oxygen affinity modified hemoglobin
DE10212321A1 (de) 2002-03-20 2003-10-09 Sanguibio Tech Ag Verwendung eines oder mehrerer von Plasma und Zellwandbestandteilen befreiten natürlichen oder modifizierten Sauerstoffbinder zur externen Behandlung offener, insbesondere chronischer Wunden
JP2004307404A (ja) 2003-04-08 2004-11-04 Nipro Corp 人工酸素運搬体を含む医薬組成物
US20040265835A1 (en) 2003-06-30 2004-12-30 Lemaster David M. Method of sorting vesicle-entrapped, coupled nucleic acid-protein displays
US7682603B2 (en) 2003-07-25 2010-03-23 The Trustees Of The University Of Pennsylvania Polymersomes incorporating highly emissive probes
US8945629B2 (en) 2004-09-10 2015-02-03 University Of Wyoming Nanoparticles for cytoplasmic drug delivery to cancer cells
US7897585B1 (en) 2005-01-04 2011-03-01 Gp Medical, Inc. Nanoparticles for protein drug delivery
JP4665791B2 (ja) 2005-04-15 2011-04-06 ニプロ株式会社 酸素運搬体の脱一酸化炭素化方法、脱一酸化炭素化された酸素運搬体、その医薬組成物及び脱一酸化炭素化装置
US20080102128A1 (en) 2006-07-28 2008-05-01 Flamel Technologies, Inc. Modified-release microparticles based on amphiphilic copolymer and on active principles(s) and pharmaceutical formulations comprising them
EP2086591A4 (en) 2006-11-14 2011-06-22 Univ Pennsylvania EFFICIENT NUCLEAR DISTRIBUTION OF ANTISENSE OLIGONUCLEOTIDES
EP2170267A4 (en) 2007-06-28 2011-04-27 Agency Science Tech & Res CATIONIC PEPTIDE FOR RELEASING AN AGENT IN A CELL
US8591921B2 (en) 2008-04-10 2013-11-26 Virginia Commonwealth University Induction of tumor hypoxia for cancer therapy
WO2010068432A1 (en) 2008-11-25 2010-06-17 Ecole Polytechnique Federale De Lausanne (Epfl) Block copolymers and uses thereof
CA2756670A1 (en) 2009-03-26 2010-09-30 The Regents Of The University Of California Mesenchymal stem cells producing inhibitory rna for disease modification
DK2417262T3 (da) 2009-04-07 2015-06-22 Dow Agrosciences Llc Nanopartikelmedieret tilførsel af sekvensspecifikke nukleaser
US20100331819A1 (en) 2009-06-24 2010-12-30 Abbott Cardiovascular Systems Inc. Drug Delivery System and Method of Treatment of Vascular Diseases Using Photodynamic Therapy
WO2011011678A2 (en) 2009-07-24 2011-01-27 Transposagen Biopharmaceuticals, Inc. Genetically modified rat models for cytokine-cytokine signaling pathways
US8420118B2 (en) 2009-09-10 2013-04-16 The Board Of Regents Of The University Of Oklahoma Anionic lipids and lipid nano-structures and methods of producing and using same
WO2011106376A2 (en) 2010-02-23 2011-09-01 The General Hospital Corporation Use of microvesicles in the treatment of medical conditions
CA2792035A1 (en) 2010-03-02 2011-09-09 Vindico Nanobio Technology, Inc. Compositions and methods for treating or preventing immuno-inflammatory disease
US9044454B2 (en) 2010-03-10 2015-06-02 Northwestern University Regulation of microvasculature occlusion
US8808748B2 (en) 2010-04-20 2014-08-19 Vindico NanoBio Technology Inc. Biodegradable nanoparticles as novel hemoglobin-based oxygen carriers and methods of using the same
EP2462854A1 (de) 2010-12-09 2012-06-13 Miele & Cie. KG System bestehend aus einem Staubsauger und einem Staubbeutel
US20140363496A1 (en) 2011-01-07 2014-12-11 Vindico NanoBio Technology Inc. Compositions and Methods for Inducing Nanoparticle-mediated Microvascular Embolization of Tumors
PT2661275T (pt) 2011-01-07 2019-04-24 Poseida Therapeutics Inc Composições e métodos para a entrega a tumores de agentes ligantes de elevada afinidade para o oxigénio
JP2015180606A (ja) 2012-08-01 2015-10-15 アステラス製薬株式会社 抗癌剤の併用による癌治療方法
MX2015007550A (es) 2012-12-12 2017-02-02 Broad Inst Inc Suministro, modificación y optimización de sistemas, métodos y composiciones para la manipulación de secuencias y aplicaciones terapéuticas.
SG10201912327SA (en) 2012-12-12 2020-02-27 Broad Inst Inc Engineering and Optimization of Improved Systems, Methods and Enzyme Compositions for Sequence Manipulation
ES2901396T3 (es) 2013-03-14 2022-03-22 Caribou Biosciences Inc Composiciones y métodos de ácidos nucleicos dirigidos a ácido nucleico
AU2014346559B2 (en) 2013-11-07 2020-07-09 Editas Medicine,Inc. CRISPR-related methods and compositions with governing gRNAs
MX2016007328A (es) 2013-12-12 2017-07-19 Broad Inst Inc Suministro, uso y aplicaciones terapeuticas de sistemas y composiciones crispr-cas para edicion del genoma.
CA2951707A1 (en) 2014-06-10 2015-12-17 Massachusetts Institute Of Technology Method for gene editing
JP6764864B2 (ja) 2014-08-08 2020-10-07 ポセイダ セラピューティクス， インコーポレイテッド 腫瘍のナノ粒子媒介微小血管塞栓形成を誘導するための組成物および方法
EP3226890A4 (en) 2014-12-05 2018-07-25 Vindico Nanobiotechnology, LLC. Compositions and methods for inducing nanoparticle-mediated microvascular embolization of tumors
US20170000743A1 (en) 2015-07-02 2017-01-05 Vindico NanoBio Technology Inc. Compositions and Methods for Delivery of Gene Editing Tools Using Polymeric Vesicles
US10456452B2 (en) 2015-07-02 2019-10-29 Poseida Therapeutics, Inc. Compositions and methods for improved encapsulation of functional proteins in polymeric vesicles
WO2017190091A1 (en) 2016-04-29 2017-11-02 Vindico Nanobiotechnology, Llc Poly(histidine)-based micelles for complexation and delivery of proteins and nucleic acids

Also Published As

Publication number Publication date
WO2017004498A1 (en) 2017-01-05
US20200009231A1 (en) 2020-01-09
EP3316861A1 (en) 2018-05-09
AU2016287579B2 (en) 2021-04-01
JP2018521128A (ja) 2018-08-02
CN108348467B (zh) 2021-08-24
AU2016287579A1 (en) 2018-01-25
CA2991101C (en) 2023-07-11
US10987409B2 (en) 2021-04-27
CA2991101A1 (en) 2017-01-05
JP6840750B2 (ja) 2021-03-10
EP3316861B1 (en) 2023-02-15
EP3316861A4 (en) 2019-03-13
CN108348467A (zh) 2018-07-31
US10456452B2 (en) 2019-10-29
US20170000734A1 (en) 2017-01-05

Similar Documents

Publication Publication Date Title
HK1255210A1 (zh) 用於改進聚合物囊泡中功能性蛋白質的包封的組合物和方法
IL262321A (en) Preparations and methods for selective protein expression
HK1258900A1 (zh) 遞送方法和組合物
HK1253306A1 (zh) 抗ntb-a抗體及相關組合物和方法
IL259023A (en) Preparations containing protein-charged exosomes, methods for their production and uses thereof
GB2546350B (en) Compositions and methods
HK1246097A1 (zh) 含有殼多糖和可消化蛋白的組合物
HK1252260A1 (zh) 基於絲的保濕劑組合物及其方法
GB201718876D0 (en) Antithrombin-heparin compositions and methods
HK1245158A1 (zh) 阿吡莫德組合物及其使用方法
IL265831A (en) Preparations and methods for protein expression and administration
GB201520255D0 (en) Composition and method
HK1258371A1 (zh) 止血組合物和使用止血組合物的止血方法
EP2960292A4 (en) NANOCOMPOSITE COMPOSITION BASED ON CHLOROETHYLENE AND METHOD FOR PREPARING THE SAME
HK1214767A1 (zh) 片劑形式的藥物組合物及其製造方法
HK1250726A1 (zh) 含有氨基酸及環狀二肽的組合物
EP2956469A4 (en) METHODS AND COMPOSITIONS FOR CONCENTRATING PROTEINS
IL251236A0 (en) Preparations containing glycosaminoglycans and proteins and their uses
GB201512996D0 (en) Compositions and methods
GB201509420D0 (en) Composition and method
PL3072529T3 (pl) Kompozycja zawierająca wemurafenib i HPMC-AS
GB201514413D0 (en) Compositions and methods
GB201513492D0 (en) Method and composition
IL256261B (en) Hide1 compositions and methods
GB201522554D0 (en) Methods and compositions