HK1255210A1 - 用於改進聚合物囊泡中功能性蛋白質的包封的組合物和方法 - Google Patents
用於改進聚合物囊泡中功能性蛋白質的包封的組合物和方法Info
- Publication number
- HK1255210A1 HK1255210A1 HK18114338.2A HK18114338A HK1255210A1 HK 1255210 A1 HK1255210 A1 HK 1255210A1 HK 18114338 A HK18114338 A HK 18114338A HK 1255210 A1 HK1255210 A1 HK 1255210A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- compositions
- methods
- functional proteins
- polymeric vesicles
- improved encapsulation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/41—Porphyrin- or corrin-ring-containing peptides
- A61K38/42—Haemoglobins; Myoglobins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
- A61K9/1273—Polymersomes; Liposomes with polymerisable or polymerised bilayer-forming substances
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Dispersion Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Preparation (AREA)
- Inorganic Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562187942P | 2015-07-02 | 2015-07-02 | |
US15/198,836 US10456452B2 (en) | 2015-07-02 | 2016-06-30 | Compositions and methods for improved encapsulation of functional proteins in polymeric vesicles |
PCT/US2016/040657 WO2017004498A1 (en) | 2015-07-02 | 2016-07-01 | Compositions and methods for improved encapsulation of functional proteins in polymeric vesicles |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1255210A1 true HK1255210A1 (zh) | 2019-08-09 |
Family
ID=57609207
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK18114338.2A HK1255210A1 (zh) | 2015-07-02 | 2018-11-09 | 用於改進聚合物囊泡中功能性蛋白質的包封的組合物和方法 |
Country Status (8)
Country | Link |
---|---|
US (2) | US10456452B2 (zh) |
EP (1) | EP3316861B1 (zh) |
JP (1) | JP6840750B2 (zh) |
CN (1) | CN108348467B (zh) |
AU (1) | AU2016287579B2 (zh) |
CA (1) | CA2991101C (zh) |
HK (1) | HK1255210A1 (zh) |
WO (1) | WO2017004498A1 (zh) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10456452B2 (en) | 2015-07-02 | 2019-10-29 | Poseida Therapeutics, Inc. | Compositions and methods for improved encapsulation of functional proteins in polymeric vesicles |
US11213594B2 (en) | 2016-04-29 | 2022-01-04 | Poseida Therapeutics, Inc. | Poly(histidine)-based micelles for complexation and delivery of proteins and nucleic acids |
US20190119636A1 (en) | 2017-10-23 | 2019-04-25 | Poseida Therapeutics, Inc. | Modified stem cell memory t cells, methods of making and methods of using same |
CN110199015A (zh) | 2016-09-30 | 2019-09-03 | 波赛达治疗公司 | 修饰干细胞记忆t细胞、其制造方法与使用方法 |
WO2018068022A1 (en) | 2016-10-06 | 2018-04-12 | Poseida Therapeutics, Inc. | Inducible caspases and methods for use |
US10329543B2 (en) | 2017-10-23 | 2019-06-25 | Poseida Therapeutics, Inc. | Modified stem cell memory T cells, methods of making and methods of using same |
US20220042038A1 (en) | 2018-12-20 | 2022-02-10 | Poseida Therapeutics, Inc. | Nanotransposon compositions and methods of use |
EP3739321B1 (de) * | 2019-05-17 | 2023-03-08 | Xtal Concepts GmbH | Qualifizierungsverfahren für kryoelektronenmikroskopie-proben sowie dazugehöriger probenhalter |
KR20220057596A (ko) | 2019-09-05 | 2022-05-09 | 포세이다 테라퓨틱스, 인크. | 동종이계 세포 조성물 및 사용 방법 |
WO2021127505A1 (en) | 2019-12-20 | 2021-06-24 | Poseida Therapeutics, Inc. | Anti-muc1 compositions and methods of use |
WO2021183795A1 (en) | 2020-03-11 | 2021-09-16 | Poseida Therapeutics, Inc. | Chimeric stimulatory receptors and methods of use in t cell activation and differentiation |
US20240060090A1 (en) | 2021-02-23 | 2024-02-22 | Poseida Therapeutics, Inc. | Genetically modified induced pluripotent stem cells and methods of use thereof |
CN113264997B (zh) * | 2021-04-13 | 2023-07-04 | 康汉医药(广州)有限公司 | 一种蛋白药物在常温、高温条件下保存的方法 |
KR20240095537A (ko) | 2021-10-04 | 2024-06-25 | 포세이다 테라퓨틱스, 인크. | 트랜스포존 조성물 및 이의 이용 방법 |
WO2023164573A1 (en) | 2022-02-23 | 2023-08-31 | Poseida Therapeutics, Inc. | Genetically modified cells and methods of use thereof |
CN115710581A (zh) * | 2022-11-16 | 2023-02-24 | 哈尔滨工业大学 | 一种提高酶利用率的蛋白质囊泡聚集体的构建方法 |
WO2024178069A1 (en) | 2023-02-21 | 2024-08-29 | Poseida Therapeutics, Inc. | Compositions and methods for genome editing |
WO2024178055A1 (en) | 2023-02-21 | 2024-08-29 | Poseida Therapeutics, Inc. | Compositions and methods for genome editing |
Family Cites Families (52)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5227170A (en) | 1989-06-22 | 1993-07-13 | Vestar, Inc. | Encapsulation process |
US5256422A (en) | 1991-03-28 | 1993-10-26 | Micro Vesicular Systems, Inc. | Lipid vesicle containing water-in-oil emulsions |
US5612310A (en) | 1993-05-24 | 1997-03-18 | Duke University | Methods for improving therapeutic effectiveness of agents for the treatment of solid tumors and other disorders |
US5595756A (en) | 1993-12-22 | 1997-01-21 | Inex Pharmaceuticals Corporation | Liposomal compositions for enhanced retention of bioactive agents |
US5833974A (en) | 1996-04-17 | 1998-11-10 | Teicher; Beverly A. | Method of enhancing the effective life of oxygen-delivery agents |
GB9624540D0 (en) | 1996-11-26 | 1997-01-15 | Nycomed Imaging As | Compositions |
CA2337060A1 (en) | 1998-07-10 | 2000-01-20 | Jonathan S. Stamler | Therapies using hemoproteins |
JP2002529521A (ja) | 1998-11-12 | 2002-09-10 | ノヴォリティックス インコーポレイテッド | 血管閉塞を生成する組成物および方法 |
US20080181939A1 (en) | 1999-12-14 | 2008-07-31 | Trustees Of The University Of Pennsylvania | Polymersomes and related encapsulating membranes |
US6835394B1 (en) | 1999-12-14 | 2004-12-28 | The Trustees Of The University Of Pennsylvania | Polymersomes and related encapsulating membranes |
WO2001080890A2 (en) | 2000-04-26 | 2001-11-01 | Queen's University At Kingston | Formulations and methods of using nitric oxide mimetics against a malignant cell phenotype |
US6376525B1 (en) | 2000-09-15 | 2002-04-23 | Qingzhong Kong | Method and composition for treating cancer using cellular organelle crystallizing agents |
US20020115216A1 (en) | 2000-05-19 | 2002-08-22 | Steer Clifford J. | Composition for delivery of compounds to cells |
DE10031741A1 (de) | 2000-06-29 | 2002-01-17 | Sanguibio Tech Ag | Einen Sauerstoffträger, ausgewählt aus Hämoglobin oder Hämoglobin- und Myoglobin-enthaltende Zubereitung als Externum zur natürlichen Regeneration der Haut bei Sauerstoff-Mangel |
ATE400250T1 (de) | 2001-09-12 | 2008-07-15 | Virexx Medical Corp | Festphasenmittel zur vaskulären okklusion mit immobilisierter thrombozyten-bindungssubstanz |
US20030153491A1 (en) | 2002-01-11 | 2003-08-14 | Winslow Robert M. | Methods and compositions for oxygen transport comprising a high oxygen affinity modified hemoglobin |
DE10212321A1 (de) | 2002-03-20 | 2003-10-09 | Sanguibio Tech Ag | Verwendung eines oder mehrerer von Plasma und Zellwandbestandteilen befreiten natürlichen oder modifizierten Sauerstoffbinder zur externen Behandlung offener, insbesondere chronischer Wunden |
JP2004307404A (ja) | 2003-04-08 | 2004-11-04 | Nipro Corp | 人工酸素運搬体を含む医薬組成物 |
US20040265835A1 (en) | 2003-06-30 | 2004-12-30 | Lemaster David M. | Method of sorting vesicle-entrapped, coupled nucleic acid-protein displays |
US7682603B2 (en) | 2003-07-25 | 2010-03-23 | The Trustees Of The University Of Pennsylvania | Polymersomes incorporating highly emissive probes |
US8945629B2 (en) | 2004-09-10 | 2015-02-03 | University Of Wyoming | Nanoparticles for cytoplasmic drug delivery to cancer cells |
US7897585B1 (en) | 2005-01-04 | 2011-03-01 | Gp Medical, Inc. | Nanoparticles for protein drug delivery |
JP4665791B2 (ja) | 2005-04-15 | 2011-04-06 | ニプロ株式会社 | 酸素運搬体の脱一酸化炭素化方法、脱一酸化炭素化された酸素運搬体、その医薬組成物及び脱一酸化炭素化装置 |
US20080102128A1 (en) | 2006-07-28 | 2008-05-01 | Flamel Technologies, Inc. | Modified-release microparticles based on amphiphilic copolymer and on active principles(s) and pharmaceutical formulations comprising them |
WO2008060557A2 (en) | 2006-11-14 | 2008-05-22 | The Trustees Of The University Of Pennsylvania | Efficient nuclear delivery of antisense oligonucleotides |
WO2009002274A1 (en) | 2007-06-28 | 2008-12-31 | Agency For Science, Technology And Research | Cationic peptide for delivering an agent into a cell |
CN102026634B (zh) | 2008-04-10 | 2014-01-22 | 弗吉尼亚州立邦联大学 | 诱导肿瘤缺氧以治疗癌症 |
US9271929B2 (en) | 2008-11-25 | 2016-03-01 | École Polytechnique Fédérale De Lausanne (Epfl) | Block copolymers and uses thereof |
EP2411505A4 (en) | 2009-03-26 | 2013-01-30 | Univ California | MESENCHYMAL STEM CELLS PRODUCING INHIBITORY RNA WHICH CAN BE USED TO ACT IN THE COURSE OF A DISEASE |
CN102369287B (zh) | 2009-04-07 | 2014-09-17 | 陶氏益农公司 | 纳米颗粒介导的序列特异性核酸酶的投递 |
US20100331819A1 (en) | 2009-06-24 | 2010-12-30 | Abbott Cardiovascular Systems Inc. | Drug Delivery System and Method of Treatment of Vascular Diseases Using Photodynamic Therapy |
WO2011011678A2 (en) | 2009-07-24 | 2011-01-27 | Transposagen Biopharmaceuticals, Inc. | Genetically modified rat models for cytokine-cytokine signaling pathways |
US8420118B2 (en) | 2009-09-10 | 2013-04-16 | The Board Of Regents Of The University Of Oklahoma | Anionic lipids and lipid nano-structures and methods of producing and using same |
WO2011106376A2 (en) | 2010-02-23 | 2011-09-01 | The General Hospital Corporation | Use of microvesicles in the treatment of medical conditions |
US20130202712A1 (en) | 2010-03-02 | 2013-08-08 | Vindico Nanobio Technology, Inc. | Compositions And Methods For Treating Or Preventing Immuno-Inflammatory Disease |
US9044454B2 (en) | 2010-03-10 | 2015-06-02 | Northwestern University | Regulation of microvasculature occlusion |
US8808748B2 (en) | 2010-04-20 | 2014-08-19 | Vindico NanoBio Technology Inc. | Biodegradable nanoparticles as novel hemoglobin-based oxygen carriers and methods of using the same |
EP2462854A1 (de) | 2010-12-09 | 2012-06-13 | Miele & Cie. KG | System bestehend aus einem Staubsauger und einem Staubbeutel |
US20140363496A1 (en) | 2011-01-07 | 2014-12-11 | Vindico NanoBio Technology Inc. | Compositions and Methods for Inducing Nanoparticle-mediated Microvascular Embolization of Tumors |
ES2718308T3 (es) | 2011-01-07 | 2019-07-01 | Poseida Therapeutics Inc | Composiciones y métodos para la administración a tumores de agentes de unión de alta afinidad al oxígeno |
JP2015180606A (ja) | 2012-08-01 | 2015-10-15 | アステラス製薬株式会社 | 抗癌剤の併用による癌治療方法 |
SG11201504523UA (en) | 2012-12-12 | 2015-07-30 | Broad Inst Inc | Delivery, engineering and optimization of systems, methods and compositions for sequence manipulation and therapeutic applications |
DK3064585T3 (da) | 2012-12-12 | 2020-04-27 | Broad Inst Inc | Konstruering og optimering af forbedrede systemer, fremgangsmåder og enzymsammensætninger til sekvensmanipulation |
EP2971167B1 (en) | 2013-03-14 | 2019-07-31 | Caribou Biosciences, Inc. | Compositions and methods of nucleic acid-targeting nucleic acids |
CA2930015A1 (en) | 2013-11-07 | 2015-05-14 | Editas Medicine, Inc. | Crispr-related methods and compositions with governing grnas |
WO2015089462A1 (en) | 2013-12-12 | 2015-06-18 | The Broad Institute Inc. | Delivery, use and therapeutic applications of the crispr-cas systems and compositions for genome editing |
CA2951707A1 (en) | 2014-06-10 | 2015-12-17 | Massachusetts Institute Of Technology | Method for gene editing |
ES2822557T3 (es) | 2014-08-08 | 2021-05-04 | Poseida Therapeutics Inc | Composiciones y su uso para inducir la embolización microvascular de tumores mediada por nanopartículas |
US20170360706A1 (en) | 2014-12-05 | 2017-12-21 | Vindico Nanobiotechnology, Llc | Compositions and methods for inducing nanoparticle-mediated microvascular embolization of tumors |
US10456452B2 (en) | 2015-07-02 | 2019-10-29 | Poseida Therapeutics, Inc. | Compositions and methods for improved encapsulation of functional proteins in polymeric vesicles |
US20170000743A1 (en) | 2015-07-02 | 2017-01-05 | Vindico NanoBio Technology Inc. | Compositions and Methods for Delivery of Gene Editing Tools Using Polymeric Vesicles |
US11213594B2 (en) | 2016-04-29 | 2022-01-04 | Poseida Therapeutics, Inc. | Poly(histidine)-based micelles for complexation and delivery of proteins and nucleic acids |
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2016
- 2016-06-30 US US15/198,836 patent/US10456452B2/en active Active
- 2016-07-01 EP EP16818873.8A patent/EP3316861B1/en active Active
- 2016-07-01 WO PCT/US2016/040657 patent/WO2017004498A1/en active Application Filing
- 2016-07-01 AU AU2016287579A patent/AU2016287579B2/en active Active
- 2016-07-01 CN CN201680050917.XA patent/CN108348467B/zh active Active
- 2016-07-01 CA CA2991101A patent/CA2991101C/en active Active
- 2016-07-01 JP JP2018520384A patent/JP6840750B2/ja active Active
-
2018
- 2018-11-09 HK HK18114338.2A patent/HK1255210A1/zh unknown
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2019
- 2019-09-20 US US16/577,093 patent/US10987409B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
WO2017004498A1 (en) | 2017-01-05 |
CN108348467B (zh) | 2021-08-24 |
EP3316861A1 (en) | 2018-05-09 |
EP3316861A4 (en) | 2019-03-13 |
CA2991101C (en) | 2023-07-11 |
AU2016287579A1 (en) | 2018-01-25 |
EP3316861B1 (en) | 2023-02-15 |
AU2016287579B2 (en) | 2021-04-01 |
JP6840750B2 (ja) | 2021-03-10 |
CA2991101A1 (en) | 2017-01-05 |
US20170000734A1 (en) | 2017-01-05 |
US10456452B2 (en) | 2019-10-29 |
CN108348467A (zh) | 2018-07-31 |
JP2018521128A (ja) | 2018-08-02 |
US10987409B2 (en) | 2021-04-27 |
US20200009231A1 (en) | 2020-01-09 |
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