HK1253778A1 - 用於限制神经创伤的制剂和方法 - Google Patents

用於限制神经创伤的制剂和方法 Download PDF

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Publication number
HK1253778A1
HK1253778A1 HK18112788.1A HK18112788A HK1253778A1 HK 1253778 A1 HK1253778 A1 HK 1253778A1 HK 18112788 A HK18112788 A HK 18112788A HK 1253778 A1 HK1253778 A1 HK 1253778A1
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HK
Hong Kong
Prior art keywords
pharmaceutical
formulation
delivery device
nerve trauma
driver
Prior art date
Application number
HK18112788.1A
Other languages
English (en)
Chinese (zh)
Inventor
Timothy J. EVISTON
Arun Krishnan
Original Assignee
Intravital Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2015902089A external-priority patent/AU2015902089A0/en
Application filed by Intravital Pty Ltd filed Critical Intravital Pty Ltd
Publication of HK1253778A1 publication Critical patent/HK1253778A1/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
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    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
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    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
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    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
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    • A61M5/31581—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod performed by rotationally moving or pivoting actuator operated by user, e.g. an injection lever or handle

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
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  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Neurosurgery (AREA)
  • Inorganic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK18112788.1A 2015-06-02 2016-06-02 用於限制神经创伤的制剂和方法 HK1253778A1 (zh)

Applications Claiming Priority (6)

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AU2015902089 2015-06-02
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Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107921237A (zh) 2015-04-27 2018-04-17 反射医学公司 交感神经心肺神经调节系统和方法
WO2017139487A1 (en) 2016-02-09 2017-08-17 Northwind Medical, Inc. Methods, agents, and devices for local neuromodulation of autonomic nerves
CN110035754A (zh) 2016-06-29 2019-07-19 图拉维治疗股份有限公司 通过自主神经系统的局部神经调节治疗败血症及相关炎性病况
US20210315587A1 (en) 2018-07-02 2021-10-14 Tulavi Therapeutics, Inc. Methods and devices for in situ formed nerve cap with rapid release
AU2019299519B2 (en) 2018-07-02 2025-03-06 Incept Llc Methods and devices for in situ formed nerve cap
KR102501175B1 (ko) * 2020-02-03 2023-02-16 엠앤에이치바이오 주식회사 난청 치료용 제어 방출형 제제 및 이의 제조방법

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2221739A (en) 1939-10-16 1940-11-12 Reiter David Hypodermic syringe
US2669230A (en) 1947-07-30 1954-02-16 Becton Dickinson Co Injection apparatus
US3496937A (en) * 1967-05-18 1970-02-24 John E Balson Hypodermic syringe
DE3270634D1 (en) 1981-11-12 1986-05-22 John Joseph Jacklich A dental syringe
US4641766A (en) * 1984-11-02 1987-02-10 Alcon Laboratories, Inc. Metering dispenser for high viscosity compositions
US4659327A (en) 1985-11-26 1987-04-21 Dentsply Research & Development Corp. Multiple dosage syringe
US5922340A (en) * 1992-09-10 1999-07-13 Children's Medical Center Corporation High load formulations and methods for providing prolonged local anesthesia
US5700485A (en) * 1992-09-10 1997-12-23 Children's Medical Center Corporation Prolonged nerve blockade by the combination of local anesthetic and glucocorticoid
US6699493B2 (en) 2000-11-29 2004-03-02 Oculex Pharmaceuticals, Inc. Method for reducing or preventing transplant rejection in the eye and intraocular implants for use therefor
GB2369996B (en) * 2000-12-18 2004-06-23 S T D Pharmaceutical Products Method and apparatus for producing an injectable foam
EP2210634A1 (en) 2009-01-22 2010-07-28 Sanofi-Aventis Deutschland GmbH Drug delivery device dose setting mechanism
US8574199B2 (en) 2006-07-03 2013-11-05 Novo Nordisk A/S Coupling for injection devices
CN201033195Y (zh) * 2007-01-29 2008-03-12 吴同顺 注射器的自动扎针装置
US20080317805A1 (en) * 2007-06-19 2008-12-25 Mckay William F Locally administrated low doses of corticosteroids
US8190271B2 (en) * 2007-08-29 2012-05-29 Advanced Bionics, Llc Minimizing trauma during and after insertion of a cochlear lead
US20090263456A1 (en) 2008-04-18 2009-10-22 Warsaw Orthopedic, Inc. Methods and Compositions for Reducing Preventing and Treating Adhesives
BRPI0918297A2 (pt) * 2008-09-10 2016-05-03 Hoffmann La Roche "dispositivo de distribuição de droga para bombear a medicação para dentro do corpo de um usuário"
WO2010086273A1 (en) 2009-01-30 2010-08-05 Sanofi-Aventis Deutschland Gmbh Cartridge and medication delivery device
AU2011224884B2 (en) 2010-03-09 2013-08-15 Shl Medical Ag Medicament delivery device
WO2012021762A1 (en) 2010-08-12 2012-02-16 Tyco Healthcare Group Lp Single use device for delivery of cartridge drugs
CN103153367A (zh) 2010-08-13 2013-06-12 赛诺菲-安万特德国有限公司 用于药物输送装置贮液器的连接器
AU2011290668B2 (en) * 2010-08-19 2014-08-14 Novo Nordisk A/S Medical auto-injection device for manual needle insertion having needle shield, damping mechanism and audible and tactile feedback
JP6106666B2 (ja) 2011-07-07 2017-04-05 ノボ・ノルデイスク・エー／エス アドオン式の投薬取得／表示モジュールを備える薬剤送出注射ペン
CN103239780A (zh) * 2012-02-14 2013-08-14 上海双鸽实业有限公司 安全注射针
EP2656865A1 (en) 2012-04-24 2013-10-30 Sanofi-Aventis Deutschland GmbH Syringe carrier with needle shield and data storage device for use in a medical auto-injection device
EP2682142A1 (en) 2012-07-06 2014-01-08 Sanofi-Aventis Deutschland GmbH Autoinjector
CN103894970A (zh) * 2012-12-24 2014-07-02 健康机器人技术有限公司 用于移除注射器的针的设备
JP6215354B2 (ja) * 2013-01-23 2017-10-18 セムヌール ファーマシューティカルズ， インコーポレイテッド 不溶性コルチコステロイドおよび可溶性コルチコステロイドを含む医薬処方物
TWI772659B (zh) * 2015-01-21 2022-08-01 美商桑紐爾製藥公司 醫藥配方

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AU2016269847A1 (en) 2017-12-07
WO2016191819A1 (en) 2016-12-08
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US11857554B2 (en) 2024-01-02
CA2986447A1 (en) 2016-12-08
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US20180154080A1 (en) 2018-06-07
JP2018516910A (ja) 2018-06-28
AU2023200759A1 (en) 2023-03-09
AU2016269848A1 (en) 2017-11-30
AU2021202821A1 (en) 2021-06-03
EP3302653A1 (en) 2018-04-11
US20180185390A1 (en) 2018-07-05
US11324758B2 (en) 2022-05-10
AU2016269848B2 (en) 2021-12-09
CN107635604A (zh) 2018-01-26

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