HK1250931A1 - 誘導有絲分裂期後細胞的細胞分裂的方法 - Google Patents
誘導有絲分裂期後細胞的細胞分裂的方法Info
- Publication number
- HK1250931A1 HK1250931A1 HK18110398.7A HK18110398A HK1250931A1 HK 1250931 A1 HK1250931 A1 HK 1250931A1 HK 18110398 A HK18110398 A HK 18110398A HK 1250931 A1 HK1250931 A1 HK 1250931A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- methods
- cell division
- inducing cell
- postmitotic cells
- postmitotic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/34—Muscles; Smooth muscle cells; Heart; Cardiac stem cells; Myoblasts; Myocytes; Cardiomyocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/37—Digestive system
- A61K35/39—Pancreas; Islets of Langerhans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/45—Transferases (2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/11—Protein-serine/threonine kinases (2.7.11)
- C12Y207/11022—Cyclin-dependent kinase (2.7.11.22)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/11—Antisense
- C12N2310/111—Antisense spanning the whole gene, or a large part of it
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Cell Biology (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Developmental Biology & Embryology (AREA)
- Biotechnology (AREA)
- Gastroenterology & Hepatology (AREA)
- Virology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Marine Sciences & Fisheries (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Neurology (AREA)
- Dermatology (AREA)
- Neurosurgery (AREA)
- Ophthalmology & Optometry (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562144244P | 2015-04-07 | 2015-04-07 | |
US201562151321P | 2015-04-22 | 2015-04-22 | |
PCT/US2016/026059 WO2016164371A1 (en) | 2015-04-07 | 2016-04-05 | Methods for inducing cell division of postmitotic cells |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1250931A1 true HK1250931A1 (zh) | 2019-01-18 |
Family
ID=57072739
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK18110398.7A HK1250931A1 (zh) | 2015-04-07 | 2018-08-14 | 誘導有絲分裂期後細胞的細胞分裂的方法 |
Country Status (8)
Country | Link |
---|---|
US (3) | US10669596B2 (zh) |
EP (1) | EP3280425B1 (zh) |
JP (1) | JP6960396B2 (zh) |
CN (1) | CN107847523B (zh) |
AU (2) | AU2016246655B2 (zh) |
CA (1) | CA2982105A1 (zh) |
HK (1) | HK1250931A1 (zh) |
WO (1) | WO2016164371A1 (zh) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2016164371A1 (en) | 2015-04-07 | 2016-10-13 | The J. David Gladstone Institutes, A Testamentary Trust Established Under The Will Of J. David Gladstone | Methods for inducing cell division of postmitotic cells |
CN114075573A (zh) * | 2020-08-18 | 2022-02-22 | 中国科学院上海营养与健康研究所 | 工程改造的肝细胞 |
CN112375787A (zh) * | 2020-11-13 | 2021-02-19 | 中国人民解放军陆军特色医学中心 | 一种表征心肌细胞胞质分裂的动物模型构建方法及应用 |
TW202404993A (zh) | 2022-04-11 | 2024-02-01 | 美商特納亞治療股份有限公司 | 具經工程化蛋白殼之腺相關病毒 |
CN114716530B (zh) * | 2022-05-05 | 2023-11-10 | 明长(上海)生物医药科技有限公司 | 一种蛋白液、制备方法及应用 |
Family Cites Families (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
US5591624A (en) | 1988-03-21 | 1997-01-07 | Chiron Viagene, Inc. | Retroviral packaging cell lines |
US7070994B2 (en) | 1988-03-21 | 2006-07-04 | Oxford Biomedica (Uk) Ltd. | Packaging cells |
EP0432216A1 (en) | 1988-09-01 | 1991-06-19 | Whitehead Institute For Biomedical Research | Recombinant retroviruses with amphotropic and ecotropic host ranges |
US5585362A (en) | 1989-08-22 | 1996-12-17 | The Regents Of The University Of Michigan | Adenovirus vectors for gene therapy |
US5817491A (en) | 1990-09-21 | 1998-10-06 | The Regents Of The University Of California | VSV G pseusdotyped retroviral vectors |
DE69233013T2 (de) | 1991-08-20 | 2004-03-04 | The Government Of The United States Of America As Represented By The Secretary Of National Institute Of Health, Office Of Technology Transfer | Adenovirus vermittelter gentransfer in den gastrointestinaltrakt |
US5252479A (en) | 1991-11-08 | 1993-10-12 | Research Corporation Technologies, Inc. | Safe vector for gene therapy |
FR2688514A1 (fr) | 1992-03-16 | 1993-09-17 | Centre Nat Rech Scient | Adenovirus recombinants defectifs exprimant des cytokines et medicaments antitumoraux les contenant. |
AU680459B2 (en) | 1992-12-03 | 1997-07-31 | Genzyme Corporation | Gene therapy for cystic fibrosis |
FR2705686B1 (fr) | 1993-05-28 | 1995-08-18 | Transgene Sa | Nouveaux adénovirus défectifs et lignées de complémentation correspondantes. |
US5834256A (en) | 1993-06-11 | 1998-11-10 | Cell Genesys, Inc. | Method for production of high titer virus and high efficiency retroviral mediated transduction of mammalian cells |
JP3532566B2 (ja) | 1993-06-24 | 2004-05-31 | エル. グラハム,フランク | 遺伝子治療のためのアデノウイルスベクター |
CN1263864C (zh) | 1993-10-25 | 2006-07-12 | 坎吉公司 | 重组腺病毒载体及其使用方法 |
US6013517A (en) | 1994-05-09 | 2000-01-11 | Chiron Corporation | Crossless retroviral vectors |
FR2751345B1 (fr) | 1996-07-16 | 1998-09-18 | Univ Paris Curie | Lignees d'encapsidation hautement productrices |
US6440944B2 (en) | 1998-10-16 | 2002-08-27 | Genvec, Inc. | Methods of administering adenoviral vectors |
US7078387B1 (en) | 1998-12-28 | 2006-07-18 | Arch Development Corp. | Efficient and stable in vivo gene transfer to cardiomyocytes using recombinant adeno-associated virus vectors |
US6548261B1 (en) * | 1998-12-30 | 2003-04-15 | Case Western Reserve University | Alzheimer model for drug screening |
JP3904451B2 (ja) | 1999-06-01 | 2007-04-11 | 俊雄 北村 | パッケージング細胞 |
IL147144A0 (en) | 1999-06-18 | 2002-08-14 | Advanced Res & Tech Inst | Cardiomyocytes with enhanced proliferative potential and methods for preparing and using the same |
FR2806626B1 (fr) * | 2000-03-22 | 2003-11-28 | Centre Nat Rech Scient | Utilisation de substances modulatrices de l'expression ou de la fonction d'une proteine impliquee dans le cycle cellulaire pour le traitement ou la prevention des lesions neurales aigues |
WO2002018202A1 (de) | 2000-08-31 | 2002-03-07 | Edwin Lundgren | Steuervorrichtung für einen lenkdrachen an einem boot |
US7795032B2 (en) | 2001-05-17 | 2010-09-14 | Masaaki Ikeda | Methods for proliferating cardiomyocytes and recombinant vectors therefor |
CA2447703C (en) | 2001-05-17 | 2011-04-19 | Masaaki Ikeda | Methods for proliferating terminal differentiated cells and recombinant vectors therefor |
US20040106647A1 (en) * | 2002-06-28 | 2004-06-03 | Schneider Michael D. | Modulators of Cdk9 as a therapeutic target in cardiac hypertrophy |
EP1631306A4 (en) | 2003-05-19 | 2009-08-12 | Univ Columbia | COMPOSITIONS AND METHODS OF TREATING AND PREVENTING HEART TISSUE DEGENERATION AND THEIR USE |
ES2376239T3 (es) * | 2003-11-21 | 2012-03-12 | Daiichi Sankyo Company, Limited | Procedimiento de cultivo de células mioc�?rdicas. |
US20050266554A1 (en) | 2004-04-27 | 2005-12-01 | D Amour Kevin A | PDX1 expressing endoderm |
MXPA06008964A (es) | 2004-02-09 | 2007-02-02 | Regenion Gmbh | Inhibidores de la senalizacion de tgf-r para el tratamiento de enfermedades del snc. |
CA2767231A1 (en) * | 2009-07-06 | 2011-01-13 | Alnylam Pharmaceuticals, Inc. | Cell-based bioprocessing |
US20120121557A1 (en) | 2009-07-22 | 2012-05-17 | Children's Medical Center Corporation | Neuregulin induced proliferation of cardiomyocytes |
JP2012099199A (ja) | 2010-11-05 | 2012-05-24 | Elpida Memory Inc | 半導体装置及びその制御方法 |
US20130331389A1 (en) * | 2012-06-11 | 2013-12-12 | National Cheng Kung University | Methods and Compositions for Cardiomyocyte Replenishment by Endogenous and Progenitor Stem Cells |
US9220721B2 (en) | 2012-10-11 | 2015-12-29 | Salk Institute For Biological Studies | Methods for heart regeneration |
US9040496B2 (en) * | 2012-11-27 | 2015-05-26 | The Johns Hopkins University | Reduction of ALMS1 gene expression or inhibition of altröm protein to induce cardiomyocyte proliferation |
US9585915B2 (en) * | 2014-01-23 | 2017-03-07 | Emory University | Polypeptide hydrogels and uses related thereto |
WO2016164371A1 (en) | 2015-04-07 | 2016-10-13 | The J. David Gladstone Institutes, A Testamentary Trust Established Under The Will Of J. David Gladstone | Methods for inducing cell division of postmitotic cells |
-
2016
- 2016-04-05 WO PCT/US2016/026059 patent/WO2016164371A1/en unknown
- 2016-04-05 EP EP16777144.3A patent/EP3280425B1/en active Active
- 2016-04-05 JP JP2018503729A patent/JP6960396B2/ja active Active
- 2016-04-05 CN CN201680032785.8A patent/CN107847523B/zh active Active
- 2016-04-05 CA CA2982105A patent/CA2982105A1/en active Pending
- 2016-04-05 AU AU2016246655A patent/AU2016246655B2/en active Active
- 2016-04-05 US US15/564,752 patent/US10669596B2/en active Active
-
2018
- 2018-08-14 HK HK18110398.7A patent/HK1250931A1/zh unknown
-
2020
- 2020-02-03 US US16/779,913 patent/US11541102B2/en active Active
-
2021
- 2021-09-22 AU AU2021236501A patent/AU2021236501A1/en active Pending
-
2022
- 2022-11-29 US US18/059,621 patent/US20230310546A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
JP6960396B2 (ja) | 2021-11-05 |
JP2018512179A (ja) | 2018-05-17 |
CN107847523B (zh) | 2022-03-11 |
EP3280425A1 (en) | 2018-02-14 |
AU2016246655B2 (en) | 2021-07-22 |
EP3280425A4 (en) | 2018-12-05 |
AU2021236501A1 (en) | 2021-10-21 |
US20200165691A1 (en) | 2020-05-28 |
EP3280425B1 (en) | 2022-06-01 |
US11541102B2 (en) | 2023-01-03 |
US10669596B2 (en) | 2020-06-02 |
WO2016164371A1 (en) | 2016-10-13 |
US20180112282A1 (en) | 2018-04-26 |
AU2016246655A1 (en) | 2017-11-30 |
CA2982105A1 (en) | 2016-10-13 |
CN107847523A (zh) | 2018-03-27 |
US20230310546A1 (en) | 2023-10-05 |
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