HK1250931A1 - 誘導有絲分裂期後細胞的細胞分裂的方法 - Google Patents

誘導有絲分裂期後細胞的細胞分裂的方法

Info

Publication number
HK1250931A1
HK1250931A1 HK18110398.7A HK18110398A HK1250931A1 HK 1250931 A1 HK1250931 A1 HK 1250931A1 HK 18110398 A HK18110398 A HK 18110398A HK 1250931 A1 HK1250931 A1 HK 1250931A1
Authority
HK
Hong Kong
Prior art keywords
methods
cell division
inducing cell
postmitotic cells
postmitotic
Prior art date
Application number
HK18110398.7A
Other languages
English (en)
Inventor
Tamer M A Mohamed
Deepak Srivastava
Original Assignee
The J David Gladstone Inst A Testamentary Trust Established Under The Will Of J David Gladstone
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The J David Gladstone Inst A Testamentary Trust Established Under The Will Of J David Gladstone filed Critical The J David Gladstone Inst A Testamentary Trust Established Under The Will Of J David Gladstone
Publication of HK1250931A1 publication Critical patent/HK1250931A1/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/30Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/34Muscles; Smooth muscle cells; Heart; Cardiac stem cells; Myoblasts; Myocytes; Cardiomyocytes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37Digestive system
    • A61K35/39Pancreas; Islets of Langerhans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/45Transferases (2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y207/00Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/11Protein-serine/threonine kinases (2.7.11)
    • C12Y207/11022Cyclin-dependent kinase (2.7.11.22)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/11Antisense
    • C12N2310/111Antisense spanning the whole gene, or a large part of it

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Neurology (AREA)
  • Dermatology (AREA)
  • Neurosurgery (AREA)
  • Ophthalmology & Optometry (AREA)
HK18110398.7A 2015-04-07 2018-08-14 誘導有絲分裂期後細胞的細胞分裂的方法 HK1250931A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562144244P 2015-04-07 2015-04-07
US201562151321P 2015-04-22 2015-04-22
PCT/US2016/026059 WO2016164371A1 (en) 2015-04-07 2016-04-05 Methods for inducing cell division of postmitotic cells

Publications (1)

Publication Number Publication Date
HK1250931A1 true HK1250931A1 (zh) 2019-01-18

Family

ID=57072739

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18110398.7A HK1250931A1 (zh) 2015-04-07 2018-08-14 誘導有絲分裂期後細胞的細胞分裂的方法

Country Status (8)

Country Link
US (3) US10669596B2 (zh)
EP (1) EP3280425B1 (zh)
JP (1) JP6960396B2 (zh)
CN (1) CN107847523B (zh)
AU (2) AU2016246655B2 (zh)
CA (1) CA2982105A1 (zh)
HK (1) HK1250931A1 (zh)
WO (1) WO2016164371A1 (zh)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016164371A1 (en) 2015-04-07 2016-10-13 The J. David Gladstone Institutes, A Testamentary Trust Established Under The Will Of J. David Gladstone Methods for inducing cell division of postmitotic cells
CN114075573A (zh) * 2020-08-18 2022-02-22 中国科学院上海营养与健康研究所 工程改造的肝细胞
CN112375787A (zh) * 2020-11-13 2021-02-19 中国人民解放军陆军特色医学中心 一种表征心肌细胞胞质分裂的动物模型构建方法及应用
TW202404993A (zh) 2022-04-11 2024-02-01 美商特納亞治療股份有限公司 具經工程化蛋白殼之腺相關病毒
CN114716530B (zh) * 2022-05-05 2023-11-10 明长(上海)生物医药科技有限公司 一种蛋白液、制备方法及应用

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US5591624A (en) 1988-03-21 1997-01-07 Chiron Viagene, Inc. Retroviral packaging cell lines
US7070994B2 (en) 1988-03-21 2006-07-04 Oxford Biomedica (Uk) Ltd. Packaging cells
EP0432216A1 (en) 1988-09-01 1991-06-19 Whitehead Institute For Biomedical Research Recombinant retroviruses with amphotropic and ecotropic host ranges
US5585362A (en) 1989-08-22 1996-12-17 The Regents Of The University Of Michigan Adenovirus vectors for gene therapy
US5817491A (en) 1990-09-21 1998-10-06 The Regents Of The University Of California VSV G pseusdotyped retroviral vectors
DE69233013T2 (de) 1991-08-20 2004-03-04 The Government Of The United States Of America As Represented By The Secretary Of National Institute Of Health, Office Of Technology Transfer Adenovirus vermittelter gentransfer in den gastrointestinaltrakt
US5252479A (en) 1991-11-08 1993-10-12 Research Corporation Technologies, Inc. Safe vector for gene therapy
FR2688514A1 (fr) 1992-03-16 1993-09-17 Centre Nat Rech Scient Adenovirus recombinants defectifs exprimant des cytokines et medicaments antitumoraux les contenant.
AU680459B2 (en) 1992-12-03 1997-07-31 Genzyme Corporation Gene therapy for cystic fibrosis
FR2705686B1 (fr) 1993-05-28 1995-08-18 Transgene Sa Nouveaux adénovirus défectifs et lignées de complémentation correspondantes.
US5834256A (en) 1993-06-11 1998-11-10 Cell Genesys, Inc. Method for production of high titer virus and high efficiency retroviral mediated transduction of mammalian cells
JP3532566B2 (ja) 1993-06-24 2004-05-31 エル. グラハム,フランク 遺伝子治療のためのアデノウイルスベクター
CN1263864C (zh) 1993-10-25 2006-07-12 坎吉公司 重组腺病毒载体及其使用方法
US6013517A (en) 1994-05-09 2000-01-11 Chiron Corporation Crossless retroviral vectors
FR2751345B1 (fr) 1996-07-16 1998-09-18 Univ Paris Curie Lignees d'encapsidation hautement productrices
US6440944B2 (en) 1998-10-16 2002-08-27 Genvec, Inc. Methods of administering adenoviral vectors
US7078387B1 (en) 1998-12-28 2006-07-18 Arch Development Corp. Efficient and stable in vivo gene transfer to cardiomyocytes using recombinant adeno-associated virus vectors
US6548261B1 (en) * 1998-12-30 2003-04-15 Case Western Reserve University Alzheimer model for drug screening
JP3904451B2 (ja) 1999-06-01 2007-04-11 俊雄 北村 パッケージング細胞
IL147144A0 (en) 1999-06-18 2002-08-14 Advanced Res & Tech Inst Cardiomyocytes with enhanced proliferative potential and methods for preparing and using the same
FR2806626B1 (fr) * 2000-03-22 2003-11-28 Centre Nat Rech Scient Utilisation de substances modulatrices de l'expression ou de la fonction d'une proteine impliquee dans le cycle cellulaire pour le traitement ou la prevention des lesions neurales aigues
WO2002018202A1 (de) 2000-08-31 2002-03-07 Edwin Lundgren Steuervorrichtung für einen lenkdrachen an einem boot
US7795032B2 (en) 2001-05-17 2010-09-14 Masaaki Ikeda Methods for proliferating cardiomyocytes and recombinant vectors therefor
CA2447703C (en) 2001-05-17 2011-04-19 Masaaki Ikeda Methods for proliferating terminal differentiated cells and recombinant vectors therefor
US20040106647A1 (en) * 2002-06-28 2004-06-03 Schneider Michael D. Modulators of Cdk9 as a therapeutic target in cardiac hypertrophy
EP1631306A4 (en) 2003-05-19 2009-08-12 Univ Columbia COMPOSITIONS AND METHODS OF TREATING AND PREVENTING HEART TISSUE DEGENERATION AND THEIR USE
ES2376239T3 (es) * 2003-11-21 2012-03-12 Daiichi Sankyo Company, Limited Procedimiento de cultivo de células mioc�?rdicas.
US20050266554A1 (en) 2004-04-27 2005-12-01 D Amour Kevin A PDX1 expressing endoderm
MXPA06008964A (es) 2004-02-09 2007-02-02 Regenion Gmbh Inhibidores de la senalizacion de tgf-r para el tratamiento de enfermedades del snc.
CA2767231A1 (en) * 2009-07-06 2011-01-13 Alnylam Pharmaceuticals, Inc. Cell-based bioprocessing
US20120121557A1 (en) 2009-07-22 2012-05-17 Children's Medical Center Corporation Neuregulin induced proliferation of cardiomyocytes
JP2012099199A (ja) 2010-11-05 2012-05-24 Elpida Memory Inc 半導体装置及びその制御方法
US20130331389A1 (en) * 2012-06-11 2013-12-12 National Cheng Kung University Methods and Compositions for Cardiomyocyte Replenishment by Endogenous and Progenitor Stem Cells
US9220721B2 (en) 2012-10-11 2015-12-29 Salk Institute For Biological Studies Methods for heart regeneration
US9040496B2 (en) * 2012-11-27 2015-05-26 The Johns Hopkins University Reduction of ALMS1 gene expression or inhibition of altröm protein to induce cardiomyocyte proliferation
US9585915B2 (en) * 2014-01-23 2017-03-07 Emory University Polypeptide hydrogels and uses related thereto
WO2016164371A1 (en) 2015-04-07 2016-10-13 The J. David Gladstone Institutes, A Testamentary Trust Established Under The Will Of J. David Gladstone Methods for inducing cell division of postmitotic cells

Also Published As

Publication number Publication date
JP6960396B2 (ja) 2021-11-05
JP2018512179A (ja) 2018-05-17
CN107847523B (zh) 2022-03-11
EP3280425A1 (en) 2018-02-14
AU2016246655B2 (en) 2021-07-22
EP3280425A4 (en) 2018-12-05
AU2021236501A1 (en) 2021-10-21
US20200165691A1 (en) 2020-05-28
EP3280425B1 (en) 2022-06-01
US11541102B2 (en) 2023-01-03
US10669596B2 (en) 2020-06-02
WO2016164371A1 (en) 2016-10-13
US20180112282A1 (en) 2018-04-26
AU2016246655A1 (en) 2017-11-30
CA2982105A1 (en) 2016-10-13
CN107847523A (zh) 2018-03-27
US20230310546A1 (en) 2023-10-05

Similar Documents

Publication Publication Date Title
IL292504B1 (en) Methods of preparing t cells for t cell therapy
IL292828A (en) Central memory t cells for t cell stress therapy
HK1255161A1 (zh) 用於過繼性細胞治療的工程細胞
HK1245829A1 (zh) 受控消除治療性細胞的方法
HK1244826A1 (zh) 用於過繼細胞治療的方法和組合物
HK1245831A1 (zh) 用於生產TCRγδ+ T細胞的方法
GB201507368D0 (en) Cell
GB201503500D0 (en) Cell
HK1250931A1 (zh) 誘導有絲分裂期後細胞的細胞分裂的方法
PL3134724T3 (pl) Komórka elektrochemiczna
SI3365107T1 (sl) Celična kultura
GB201522223D0 (en) Therapeutic T cells
EP3216076C0 (en) METHOD OF USING ELECTROCHEMICAL TEST ELEMENTS WITH MULTIPLE ELECTRODE ARRANGEMENTS
GB201619821D0 (en) Advanced system for electrochemical cell
GB2539233B (en) Electrochemical cell
GB2534241B (en) Non-prismatic electrochemical cell
SG11201609269TA (en) Method of culturing cells
TWI563082B (en) Cell culture device
PT3307875T (pt) Métodos para a produção de células t tcr gamma delta+
GB201521571D0 (en) Electrochemical cell
AP2016009174A0 (en) Electrolytic cells
GB201510142D0 (en) Electrochemical cells
AU2015902675A0 (en) Adoptive t cell therapy
PL3128579T3 (pl) Ogniwo baterii
GB201406768D0 (en) Methods of cell separation