HK1247080A1 - 用於刺激細胞增殖和提供fgf2同種型的生物活性混合物的方法和組合物 - Google Patents

用於刺激細胞增殖和提供fgf2同種型的生物活性混合物的方法和組合物

Info

Publication number
HK1247080A1
HK1247080A1 HK18106025.6A HK18106025A HK1247080A1 HK 1247080 A1 HK1247080 A1 HK 1247080A1 HK 18106025 A HK18106025 A HK 18106025A HK 1247080 A1 HK1247080 A1 HK 1247080A1
Authority
HK
Hong Kong
Prior art keywords
stimulation
provision
compositions
methods
biologically active
Prior art date
Application number
HK18106025.6A
Other languages
English (en)
Inventor
‧埃兹曼 I
‧巴特斯 D
Original Assignee
桑比歐公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 桑比歐公司 filed Critical 桑比歐公司
Publication of HK1247080A1 publication Critical patent/HK1247080A1/zh

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1825—Fibroblast growth factor [FGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/33—Fibroblasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0619—Neurons
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0623—Stem cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C12N2502/1352—Mesenchymal stem cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Developmental Biology & Embryology (AREA)
  • Wood Science & Technology (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK18106025.6A 2015-04-01 2018-05-09 用於刺激細胞增殖和提供fgf2同種型的生物活性混合物的方法和組合物 HK1247080A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562178190P 2015-04-01 2015-04-01
US201562204776P 2015-08-13 2015-08-13
PCT/US2016/025559 WO2016161290A1 (en) 2015-04-01 2016-04-01 Methods and compositions for stimulation of cell proliferation and provision of biologically active mixtures of fgf2 isoforms

Publications (1)

Publication Number Publication Date
HK1247080A1 true HK1247080A1 (zh) 2018-09-21

Family

ID=57007372

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18106025.6A HK1247080A1 (zh) 2015-04-01 2018-05-09 用於刺激細胞增殖和提供fgf2同種型的生物活性混合物的方法和組合物

Country Status (8)

Country Link
US (2) US10363285B2 (zh)
EP (1) EP3277297B1 (zh)
JP (2) JP6663445B2 (zh)
CN (1) CN107427536B (zh)
CA (1) CA2981523A1 (zh)
ES (1) ES2890123T3 (zh)
HK (1) HK1247080A1 (zh)
WO (1) WO2016161290A1 (zh)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6663445B2 (ja) * 2015-04-01 2020-03-11 サンバイオ，インコーポレイティド 細胞増殖の刺激のための方法及び組成物、ならびにｆｇｆ２アイソフォームの生物学的に活性な混合物の提供
CA3030866A1 (en) 2016-07-21 2018-01-25 Sanbio, Inc. Msc growth predictor assays
CN110124009A (zh) * 2018-02-09 2019-08-16 暨南大学 一种含有能促进神经损伤修复与再生的修复肽的药物组合物及其应用
EP3873496A4 (en) * 2018-11-04 2022-11-09 Figene, LLC TREATMENT OF BRAIN HYPOXIA INCLUDING STROKE, CHRONIC TRAUMATIC ENCEPHALOPATHY AND TRAUMATIC BRAIN INJURY

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5486359A (en) 1990-11-16 1996-01-23 Osiris Therapeutics, Inc. Human mesenchymal stem cells
US20030003090A1 (en) 2001-05-31 2003-01-02 Prockop Darwin J. Directed in vitro differentiation of marrow stromal cells into neural cell progenitors
AU2003207064B2 (en) 2002-02-06 2006-07-13 Sanbio, Inc. Method of differentiating/inducing bone marrow interstitial cells into nerve cells and skeleton muscle cells by transferring Notch gene
JP4838981B2 (ja) * 2004-01-26 2011-12-14 直秀 山下 ヒト胎盤由来の間葉系細胞を含む皮膚外用剤
EP2314674A1 (en) 2004-04-12 2011-04-27 SanBio, Inc. Cells exhibiting neuronal progenitor cell characteristics
US20060216276A1 (en) * 2005-03-07 2006-09-28 Mari Dezawa Use of materials for treatment of central nervous system lesions
WO2008024996A2 (en) * 2006-08-24 2008-02-28 Johnstone Brian H Production of neural protective and regenerative factors from stem cells and treatment of nervous system conditions therewith
US8172784B2 (en) * 2006-10-11 2012-05-08 The General Hospital Corporation Compositions, methods, and devices for treating liver disease
JP5662147B2 (ja) 2007-08-15 2015-01-28 サンバイオ，インコーポレイティド 神経変性を治療するための方法及び組成物
US20110020291A1 (en) * 2007-11-17 2011-01-27 Debrabrata Banerjee Use of stem cells for wound healing
WO2011054100A1 (en) * 2009-11-05 2011-05-12 Lisheng Wang Stem cell extracts and uses thereof for immune modulation
CN107513551A (zh) * 2011-08-19 2017-12-26 桑比欧公司 神经源性因子和胶质生成性因子及其测定
WO2013112917A1 (en) * 2012-01-27 2013-08-01 Sanbio, Inc. Methods and compositions for modulating angiogenesis and vasculogenesis
WO2013172944A1 (en) * 2012-05-16 2013-11-21 Sanbio, Inc. Methods and compositions for treatment of traumatic brain injury and for modulation of migration of neurogenic cells
TWI625134B (zh) * 2014-02-17 2018-06-01 國璽幹細胞應用技術股份有限公司 間質幹細胞萃取物及其用途
JP6663445B2 (ja) * 2015-04-01 2020-03-11 サンバイオ，インコーポレイティド 細胞増殖の刺激のための方法及び組成物、ならびにｆｇｆ２アイソフォームの生物学的に活性な混合物の提供

Also Published As

Publication number Publication date
EP3277297B1 (en) 2021-07-28
US20180036378A1 (en) 2018-02-08
US11406685B2 (en) 2022-08-09
JP2020023502A (ja) 2020-02-13
JP2018511599A (ja) 2018-04-26
US10363285B2 (en) 2019-07-30
CN107427536A (zh) 2017-12-01
JP6869303B2 (ja) 2021-05-12
JP6663445B2 (ja) 2020-03-11
EP3277297A1 (en) 2018-02-07
EP3277297A4 (en) 2018-11-21
CN107427536B (zh) 2022-02-08
CA2981523A1 (en) 2016-10-06
WO2016161290A1 (en) 2016-10-06
US20190290730A1 (en) 2019-09-26
ES2890123T3 (es) 2022-01-17

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