HK1237337B - 二氟甲基-氨基吡啶和二氟甲基-氨基嘧啶 - Google Patents

二氟甲基-氨基吡啶和二氟甲基-氨基嘧啶

Info

Publication number
HK1237337B
HK1237337B HK17111163.9A HK17111163A HK1237337B HK 1237337 B HK1237337 B HK 1237337B HK 17111163 A HK17111163 A HK 17111163A HK 1237337 B HK1237337 B HK 1237337B
Authority
HK
Hong Kong
Prior art keywords
difluoromethyl
amine
triazin
pyridin
azabicyclo
Prior art date
Application number
HK17111163.9A
Other languages
German (de)
English (en)
French (fr)
Other versions
HK1237337A1 (zh
Inventor
Vladimir Cmiljanovic
Paul Hebeisen
Florent Beaufils
Thomas Bohnacker
Denise RAGEOT
Alexander SELE
Matthias Wymann
Jean-baptiste LANGLOIS
Original Assignee
Universität Basel
Torqur Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universität Basel, Torqur Ag filed Critical Universität Basel
Publication of HK1237337A1 publication Critical patent/HK1237337A1/zh
Publication of HK1237337B publication Critical patent/HK1237337B/zh

Links

Abstract

本发明涉及一种新型磷酸肌醇3-kinase ( PI3K )，哺乳动物雷帕霉素靶点( mTOR )和PI3K-related激酶( PIKKs )抑制剂的式I的化合物，其中X1、X2和X3 N或CH，条件是，至少有两个X1、X2和X3是N；Y是N或CH，这些化合物是有用的，单独使用或与另外的治疗剂，用于治疗由脂质介导的病症的激酶。
HK17111163.9A 2014-11-11 2015-11-10 二氟甲基-氨基吡啶和二氟甲基-氨基嘧啶 HK1237337B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP14192617.0 2014-11-11

Publications (2)

Publication Number Publication Date
HK1237337A1 HK1237337A1 (zh) 2018-04-13
HK1237337B true HK1237337B (zh) 2022-01-14

Family

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