HK1254517A1 - 苯並氧氮雜䓬噁唑烷酮化合物及其使用方法 - Google Patents

苯並氧氮雜䓬噁唑烷酮化合物及其使用方法

Info

Publication number
HK1254517A1
HK1254517A1 HK18113767.4A HK18113767A HK1254517A1 HK 1254517 A1 HK1254517 A1 HK 1254517A1 HK 18113767 A HK18113767 A HK 18113767A HK 1254517 A1 HK1254517 A1 HK 1254517A1
Authority
HK
Hong Kong
Prior art keywords
methods
oxazolidinone compounds
benzoxazepin oxazolidinone
benzoxazepin
compounds
Prior art date
Application number
HK18113767.4A
Other languages
English (en)
Inventor
Marie-Gabrielle Braun
Emily Hanan
Steven T Staben
Richard Elliott
Robert Andrew Heald
Calum Macleod
Original Assignee
豪夫邁‧羅氏有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 豪夫邁‧羅氏有限公司 filed Critical 豪夫邁‧羅氏有限公司
Publication of HK1254517A1 publication Critical patent/HK1254517A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HK18113767.4A 2015-07-02 2018-10-29 苯並氧氮雜䓬噁唑烷酮化合物及其使用方法 HK1254517A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562188018P 2015-07-02 2015-07-02
US201562205127P 2015-08-14 2015-08-14
PCT/EP2016/065496 WO2017001658A1 (en) 2015-07-02 2016-07-01 Benzoxazepin oxazolidinone compounds and methods of use

Publications (1)

Publication Number Publication Date
HK1254517A1 true HK1254517A1 (zh) 2019-07-19

Family

ID=56289522

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18113767.4A HK1254517A1 (zh) 2015-07-02 2018-10-29 苯並氧氮雜䓬噁唑烷酮化合物及其使用方法

Country Status (6)

Country Link
US (1) US9643980B2 (zh)
EP (1) EP3317283B1 (zh)
JP (1) JP6522807B2 (zh)
CN (2) CN111848643A (zh)
HK (1) HK1254517A1 (zh)
WO (1) WO2017001658A1 (zh)

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CN112047960A (zh) 2015-07-02 2020-12-08 豪夫迈·罗氏有限公司 苯并氧氮杂*噁唑烷酮化合物及其使用方法
EP3347361B1 (en) 2015-09-08 2020-08-05 H. Hoffnabb-La Roche Ag Tricyclic pi3k inhibitor compounds and methods of use
TW201825465A (zh) 2016-09-23 2018-07-16 美商基利科學股份有限公司 磷脂醯肌醇3-激酶抑制劑
TW201813963A (zh) 2016-09-23 2018-04-16 美商基利科學股份有限公司 磷脂醯肌醇3-激酶抑制劑
TW201815787A (zh) 2016-09-23 2018-05-01 美商基利科學股份有限公司 磷脂醯肌醇3-激酶抑制劑
CN108456172B (zh) * 2018-04-20 2021-01-12 浙江大学城市学院 一种具有苯并咪唑骨架的手性氮杂环卡宾前体化合物及其制备方法和应用
AU2019276514B2 (en) * 2018-05-30 2023-12-14 Jiangsu Hansoh Pharmaceutical Group Co., Ltd. Inhibitor containing tricyclic derivative, preparation method therefor, and application thereof
CN112424596B (zh) * 2018-09-10 2023-07-18 株式会社岛津制作所 生物膜磷酸肌醇的分离方法
WO2021088845A1 (zh) * 2019-11-04 2021-05-14 贝达药业股份有限公司 咪唑烷酮类化合物及其制备方法与应用
CN118084935A (zh) * 2019-11-04 2024-05-28 贝达药业股份有限公司 咪唑烷酮类化合物及其制备方法与应用
CN113227101A (zh) * 2019-11-25 2021-08-06 上海翰森生物医药科技有限公司 含三并环类衍生物的盐或晶型及其药物组合物
CN112830935B (zh) * 2019-11-25 2023-12-22 上海翰森生物医药科技有限公司 含三并环类衍生物自由碱的晶型及其药物组合物
WO2022237871A1 (zh) 2021-05-13 2022-11-17 贝达药业股份有限公司 咪唑烷酮类化合物的多晶型物、制备方法及其用途
CN113512733B (zh) * 2021-05-13 2022-07-26 浙江工业大学 一种电化学nhk反应合成艾日布林中间体的方法
WO2024104435A1 (zh) * 2022-11-17 2024-05-23 微境生物医药科技(上海)有限公司 三并环类PI3Kα抑制剂及其制备方法和医药用途

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UY34632A (es) * 2012-02-24 2013-05-31 Novartis Ag Compuestos de oxazolidin- 2- ona y usos de los mismos
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CN104530031A (zh) * 2014-12-10 2015-04-22 广东东阳光药业有限公司 噁唑烷酮类化合物及其在药物中的应用
CN112047960A (zh) 2015-07-02 2020-12-08 豪夫迈·罗氏有限公司 苯并氧氮杂*噁唑烷酮化合物及其使用方法

Also Published As

Publication number Publication date
EP3317283B1 (en) 2019-04-03
CN107995911B (zh) 2020-08-04
WO2017001658A1 (en) 2017-01-05
US20170002022A1 (en) 2017-01-05
US9643980B2 (en) 2017-05-09
JP2018519304A (ja) 2018-07-19
CN111848643A (zh) 2020-10-30
EP3317283A1 (en) 2018-05-09
JP6522807B2 (ja) 2019-05-29
CN107995911A (zh) 2018-05-04

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