HK1231517A1 - 用於核苷酸類似物的改進的摻入的修飾的聚合酶 - Google Patents

用於核苷酸類似物的改進的摻入的修飾的聚合酶

Info

Publication number
HK1231517A1
HK1231517A1 HK17105254.1A HK17105254A HK1231517A1 HK 1231517 A1 HK1231517 A1 HK 1231517A1 HK 17105254 A HK17105254 A HK 17105254A HK 1231517 A1 HK1231517 A1 HK 1231517A1
Authority
HK
Hong Kong
Prior art keywords
nucleotide analogues
modified polymerases
improved incorporation
incorporation
improved
Prior art date
Application number
HK17105254.1A
Other languages
English (en)
Inventor
Yao Chen Cheng
BOMATI Erin
He Molly
Original Assignee
Illumina Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Illumina Inc filed Critical Illumina Inc
Publication of HK1231517A1 publication Critical patent/HK1231517A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • C12N9/1252—DNA-directed DNA polymerase (2.7.7.7), i.e. DNA replicase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/07—Nucleotidyltransferases (2.7.7)
    • C12Y207/07007—DNA-directed DNA polymerase (2.7.7.7), i.e. DNA replicase

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
HK17105254.1A 2014-06-27 2017-05-24 用於核苷酸類似物的改進的摻入的修飾的聚合酶 HK1231517A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462018470P 2014-06-27 2014-06-27
PCT/US2015/037785 WO2015200693A1 (en) 2014-06-27 2015-06-25 Modified polymerases for improved incorporation of nucleotide analogues

Publications (1)

Publication Number Publication Date
HK1231517A1 true HK1231517A1 (zh) 2017-12-22

Family

ID=53716556

Family Applications (1)

Application Number Title Priority Date Filing Date
HK17105254.1A HK1231517A1 (zh) 2014-06-27 2017-05-24 用於核苷酸類似物的改進的摻入的修飾的聚合酶

Country Status (12)

Country Link
US (3) US9765309B2 (zh)
EP (2) EP3161154B1 (zh)
JP (3) JP6737710B2 (zh)
CN (1) CN106536728A (zh)
AU (2) AU2015279794B2 (zh)
CA (1) CA2951416A1 (zh)
DK (1) DK3161154T3 (zh)
ES (1) ES2788949T3 (zh)
HK (1) HK1231517A1 (zh)
PL (1) PL3161154T3 (zh)
PT (1) PT3161154T (zh)
WO (1) WO2015200693A1 (zh)

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Also Published As

Publication number Publication date
EP3161154B1 (en) 2020-04-15
US20150376582A1 (en) 2015-12-31
CA2951416A1 (en) 2015-12-30
US20210246435A1 (en) 2021-08-12
JP2022033882A (ja) 2022-03-02
US9765309B2 (en) 2017-09-19
AU2021290289B2 (en) 2024-02-15
PL3161154T3 (pl) 2020-10-19
US10870836B2 (en) 2020-12-22
WO2015200693A1 (en) 2015-12-30
PT3161154T (pt) 2020-06-08
ES2788949T3 (es) 2020-10-23
AU2015279794A1 (en) 2016-12-22
EP3702471A1 (en) 2020-09-02
JP6737710B2 (ja) 2020-08-12
US20170355970A1 (en) 2017-12-14
DK3161154T3 (da) 2020-06-15
JP2020127415A (ja) 2020-08-27
EP3161154A1 (en) 2017-05-03
CN106536728A (zh) 2017-03-22
AU2015279794B2 (en) 2021-09-30
JP2017518750A (ja) 2017-07-13
AU2021290289A1 (en) 2022-01-27

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