HK1231507A1 - 用於製備睫狀緣幹細胞的方法 - Google Patents

用於製備睫狀緣幹細胞的方法

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Publication number
HK1231507A1
HK1231507A1 HK17105135.6A HK17105135A HK1231507A1 HK 1231507 A1 HK1231507 A1 HK 1231507A1 HK 17105135 A HK17105135 A HK 17105135A HK 1231507 A1 HK1231507 A1 HK 1231507A1
Authority
HK
Hong Kong
Prior art keywords
manufacturing
stem cells
ciliary margin
margin stem
ciliary
Prior art date
Application number
HK17105135.6A
Other languages
English (en)
Inventor
Atsushi Kuwahara
Yoshiki Sasai
Original Assignee
Sumitomo Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co filed Critical Sumitomo Chemical Co
Publication of HK1231507A1 publication Critical patent/HK1231507A1/zh

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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/54—Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
    • A61K35/545—Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
    • A—HUMAN NECESSITIES
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    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/383—Nerve cells, e.g. dendritic cells, Schwann cells
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    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
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    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3834—Cells able to produce different cell types, e.g. hematopoietic stem cells, mesenchymal stem cells, marrow stromal cells, embryonic stem cells
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    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
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    • A61L27/3895—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells using specific culture conditions, e.g. stimulating differentiation of stem cells, pulsatile flow conditions
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  • Health & Medical Sciences (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Developmental Biology & Embryology (AREA)
  • Botany (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Wood Science & Technology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Orthopedic Medicine & Surgery (AREA)
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  • General Physics & Mathematics (AREA)
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HK17105135.6A 2014-01-17 2017-05-22 用於製備睫狀緣幹細胞的方法 HK1231507A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2014006464 2014-01-17
PCT/JP2014/077603 WO2015107738A1 (ja) 2014-01-17 2014-10-16 毛様体周縁部幹細胞の製造方法

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HK1231507A1 true HK1231507A1 (zh) 2017-12-22

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Country Status (11)

Country Link
US (1) US11724005B2 (zh)
EP (1) EP3095857A4 (zh)
JP (1) JP6571533B2 (zh)
KR (1) KR102368751B1 (zh)
CN (1) CN106062182A (zh)
AU (1) AU2014378349B2 (zh)
CA (1) CA2937129A1 (zh)
HK (1) HK1231507A1 (zh)
MY (1) MY193954A (zh)
SG (1) SG11201605833PA (zh)
WO (1) WO2015107738A1 (zh)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11241460B2 (en) 2013-03-15 2022-02-08 Astellas Institute For Regenerative Medicine Photoreceptors and photoreceptor progenitors produced from pluripotent stem cells
US10584314B2 (en) * 2014-08-08 2020-03-10 National Center For Child Health And Development Method for preparation of retinal ganglion cells
AU2015336453B2 (en) 2014-10-24 2021-05-20 Riken Production method for nerve tissue
US11214772B2 (en) 2014-10-24 2022-01-04 Sumitomo Dainippon Pharma Co., Ltd. Production method for retinal tissue
EP3348631B1 (en) * 2015-09-08 2023-11-29 Sumitomo Pharma Co., Ltd. Method for producing retinal tissue
JP7024974B2 (ja) 2016-04-20 2022-02-24 京都府公立大学法人 培養上皮シートの製造方法
CA3021828A1 (en) 2016-04-22 2017-10-26 Sumitomo Dainippon Pharma Co., Ltd. Method for producing retinal tissue
JP7150281B2 (ja) 2017-07-20 2022-10-11 国立研究開発法人理化学研究所 連続的な上皮を含む網膜組織の成熟化方法
WO2019054514A1 (ja) 2017-09-14 2019-03-21 国立研究開発法人理化学研究所 網膜組織の製造方法
CA3075883A1 (en) 2017-09-14 2019-03-21 Riken Method for amplifying cone photoreceptors or rod photoreceptors using dorsalization signal transmitter or ventralization signal transmitter
CN109423480B (zh) * 2017-12-21 2022-04-12 中山大学中山眼科中心 一种人多能干细胞分化为视网膜组织的简易高效可机械化的诱导方法
CN116445409B (zh) * 2023-06-16 2023-09-22 中国人民解放军总医院第三医学中心 视杆感光前体细胞的制备方法及其应用

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5734998A (en) 1997-01-10 1998-08-03 Life Technologies, Inc. Embryonic stem cell serum replacement
JP2006506970A (ja) 2002-07-12 2006-03-02 ユニバーシティ オブ ワシントン 神経細胞の延長されたインビトロ培養のための方法および系
JP2006517101A (ja) * 2003-01-13 2006-07-20 エス． ラオ、マヘンドラ 治療用産物を送達するための、増殖性の幹細胞および前駆細胞における候補分子の持続的発現
US20050048041A1 (en) 2003-01-13 2005-03-03 Rao Mahendra S. Persistent expression of candidate molecule in proliferating stem and progenitor cells for delivery of therapeutic products
ES2334231T3 (es) * 2003-01-28 2010-03-08 F. Hoffmann-La Roche Ag Uso de secuencias regulatorias para la expresion transitoria especifica en celulas determinadas de manera neuronal.
JP5141016B2 (ja) * 2004-06-18 2013-02-13 独立行政法人理化学研究所 無血清浮遊培養による胚性幹細胞の神経分化誘導法
US20090170148A1 (en) * 2007-08-13 2009-07-02 Smirnova Yulia A Nanog+, OCT-4+ Retinal Pigment Epithelial Stem Cells and Methods for Their Use and Manufacture
WO2009132156A1 (en) * 2008-04-22 2009-10-29 Regenerative Research Foundation Retinal pigment epithelial stem cells
EP2314671B1 (en) 2008-06-06 2022-08-03 Riken Method for culture of stem cell
WO2012173207A1 (ja) * 2011-06-14 2012-12-20 独立行政法人理化学研究所 網膜細胞への分化誘導方法
EP2554662A1 (en) 2011-08-05 2013-02-06 M Maria Pia Cosma Methods of treatment of retinal degeneration diseases
JP6067232B2 (ja) * 2011-11-25 2017-01-25 住友化学株式会社 網膜層特異的神経細胞を製造する方法
JP5985209B2 (ja) * 2011-11-25 2016-09-06 住友化学株式会社 眼杯様構造体の製造方法
CN113817679A (zh) * 2011-11-25 2021-12-21 住友化学株式会社 制备视网膜组织和视网膜相关细胞的方法
EP3842524A1 (en) * 2012-06-08 2021-06-30 Sumitomo Chemical Company, Limited Method for producing ciliary marginal zone-like structure
WO2015087614A1 (ja) 2013-12-11 2015-06-18 住友化学株式会社 毛様体周縁部様構造体の製造法

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MY193954A (en) 2022-11-02
CN106062182A (zh) 2016-10-26
US20170319748A1 (en) 2017-11-09
KR20160105905A (ko) 2016-09-07
CA2937129A1 (en) 2015-07-23
AU2014378349B2 (en) 2021-06-03
AU2014378349A1 (en) 2016-09-01
KR102368751B1 (ko) 2022-03-03
JP6571533B2 (ja) 2019-09-04
JPWO2015107738A1 (ja) 2017-03-23
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US11724005B2 (en) 2023-08-15

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