HK1222653A1 - 新的用於治療和預防呼吸道合胞病毒感染的氮雜-氧代-吲哚 - Google Patents

新的用於治療和預防呼吸道合胞病毒感染的氮雜-氧代-吲哚

Info

Publication number
HK1222653A1
HK1222653A1 HK16110819.0A HK16110819A HK1222653A1 HK 1222653 A1 HK1222653 A1 HK 1222653A1 HK 16110819 A HK16110819 A HK 16110819A HK 1222653 A1 HK1222653 A1 HK 1222653A1
Authority
HK
Hong Kong
Prior art keywords
indoles
prophylaxis
oxo
treatment
virus infection
Prior art date
Application number
HK16110819.0A
Other languages
English (en)
Inventor
Lu Gao
Lei Guo
Chungen Liang
Baoxia Wang
Lisha Wang
Hongying Yun
Weixing Zhang
Xiufang Zheng
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of HK1222653A1 publication Critical patent/HK1222653A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
HK16110819.0A 2013-08-12 2016-09-13 新的用於治療和預防呼吸道合胞病毒感染的氮雜-氧代-吲哚 HK1222653A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN2013081263 2013-08-12
PCT/EP2014/067046 WO2015022263A1 (en) 2013-08-12 2014-08-08 Novel aza-oxo-indoles for the treatment and prophylaxis of respiratory syncytial virus infection

Publications (1)

Publication Number Publication Date
HK1222653A1 true HK1222653A1 (zh) 2017-07-07

Family

ID=51298768

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16110819.0A HK1222653A1 (zh) 2013-08-12 2016-09-13 新的用於治療和預防呼吸道合胞病毒感染的氮雜-氧代-吲哚

Country Status (9)

Country Link
US (1) US9670211B2 (zh)
EP (1) EP3033341B1 (zh)
JP (1) JP6211195B2 (zh)
BR (1) BR112016002638A2 (zh)
CA (1) CA2914529A1 (zh)
HK (1) HK1222653A1 (zh)
MX (1) MX2016001855A (zh)
RU (1) RU2016105970A (zh)
WO (1) WO2015022263A1 (zh)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014149819A1 (en) 2013-03-14 2014-09-25 Kalyra Pharmaceuticals, Inc. Bicyclic analgesic compounds
EP3033333A1 (en) * 2013-08-15 2016-06-22 F. Hoffmann-La Roche AG Novel aza-oxo-indoles for the treatment and prophylaxis of respiratory syncytial virus infection
CN108947867A (zh) 2013-12-12 2018-12-07 卡利拉制药公司 双环烷基化合物及合成
EP3114107B1 (en) 2014-03-07 2020-07-22 Recurium IP Holdings, LLC Propellane derivates and synthesis
GB201417707D0 (en) * 2014-10-07 2014-11-19 Viral Ltd Pharmaceutical compounds
US20190060257A1 (en) * 2016-03-16 2019-02-28 Zeno Royalties & Milestones, LLC Analgesic compounds
GB201711704D0 (en) * 2017-07-20 2017-09-06 Reviral Ltd Pharmaceutical compounds
MA53558A (fr) 2018-09-06 2021-09-15 Cidara Therapeutics Inc Compositions et procédés pour le traitement d'infections virales
MX2022002842A (es) * 2019-09-09 2022-06-14 Cidara Therapeutics Inc Composiciones y metodos para el tratamiento del virus sincitial respiratorio.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI501967B (zh) * 2010-12-16 2015-10-01 Janssen R&D Ireland 作為呼吸道融合病毒抗病毒劑之氮雜吲哚類
GB201119538D0 (en) * 2011-11-10 2011-12-21 Viral Ltd Pharmaceutical compounds
US9617289B2 (en) * 2012-10-16 2017-04-11 Janssen Sciences Ireland Uc RSV antiviral compounds
MX2015015691A (es) * 2013-05-14 2016-03-04 Hoffmann La Roche Aza-oxo-indoles novedosos para el tratamiento y profilaxis de la infeccion del virus sincital respiratorio.

Also Published As

Publication number Publication date
EP3033341A1 (en) 2016-06-22
EP3033341B1 (en) 2017-05-03
US9670211B2 (en) 2017-06-06
JP6211195B2 (ja) 2017-10-11
JP2016530257A (ja) 2016-09-29
BR112016002638A2 (pt) 2017-08-01
MX2016001855A (es) 2016-05-24
CA2914529A1 (en) 2015-02-19
US20160229853A1 (en) 2016-08-11
WO2015022263A1 (en) 2015-02-19
RU2016105970A (ru) 2017-09-19

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