HK1222653A1 - 新的用於治療和預防呼吸道合胞病毒感染的氮雜-氧代-吲哚 - Google Patents

新的用於治療和預防呼吸道合胞病毒感染的氮雜-氧代-吲哚

Info

Publication number
HK1222653A1
HK1222653A1 HK16110819.0A HK16110819A HK1222653A1 HK 1222653 A1 HK1222653 A1 HK 1222653A1 HK 16110819 A HK16110819 A HK 16110819A HK 1222653 A1 HK1222653 A1 HK 1222653A1
Authority
HK
Hong Kong
Prior art keywords
indoles
prophylaxis
oxo
treatment
virus infection
Prior art date
Application number
HK16110819.0A
Other languages
English (en)
Inventor
Lu Gao
Lei Guo
Chungen Liang
Baoxia Wang
Lisha Wang
Hongying Yun
Weixing Zhang
Xiufang Zheng
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of HK1222653A1 publication Critical patent/HK1222653A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
HK16110819.0A 2013-08-12 2016-09-13 新的用於治療和預防呼吸道合胞病毒感染的氮雜-氧代-吲哚 HK1222653A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN2013081263 2013-08-12
PCT/EP2014/067046 WO2015022263A1 (en) 2013-08-12 2014-08-08 Novel aza-oxo-indoles for the treatment and prophylaxis of respiratory syncytial virus infection

Publications (1)

Publication Number Publication Date
HK1222653A1 true HK1222653A1 (zh) 2017-07-07

Family

ID=51298768

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16110819.0A HK1222653A1 (zh) 2013-08-12 2016-09-13 新的用於治療和預防呼吸道合胞病毒感染的氮雜-氧代-吲哚

Country Status (9)

Country Link
US (1) US9670211B2 (zh)
EP (1) EP3033341B1 (zh)
JP (1) JP6211195B2 (zh)
BR (1) BR112016002638A2 (zh)
CA (1) CA2914529A1 (zh)
HK (1) HK1222653A1 (zh)
MX (1) MX2016001855A (zh)
RU (1) RU2016105970A (zh)
WO (1) WO2015022263A1 (zh)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2970104B1 (en) 2013-03-14 2019-04-24 Zeno Royalties & Milestones, LLC Bicyclic analgesic compounds
WO2015022301A1 (en) * 2013-08-15 2015-02-19 F. Hoffmann-La Roche Ag Novel aza-oxo-indoles for the treatment and prophylaxis of respiratory syncytial virus infection
JP6542794B2 (ja) 2013-12-12 2019-07-10 ゼノ ロイアルティー アンド マイルストーンズ リミテッド ライアビリティー カンパニー 二環式アルキル化合物、および合成
CA2942144C (en) 2014-03-07 2023-08-22 Kalyra Pharmaceuticals, Inc. Propellane derivates and synthesis
GB201417707D0 (en) * 2014-10-07 2014-11-19 Viral Ltd Pharmaceutical compounds
WO2017160926A1 (en) * 2016-03-16 2017-09-21 Kalyra Pharmaceuticals, Inc. Analgesic compounds
GB201711704D0 (en) * 2017-07-20 2017-09-06 Reviral Ltd Pharmaceutical compounds
JP2021536483A (ja) 2018-09-06 2021-12-27 シダラ セラピューティクス インコーポレーテッド ウイルス感染症の治療のための組成物及び方法
JP2022547538A (ja) * 2019-09-09 2022-11-14 シダラ セラピューティクス インコーポレーテッド 呼吸器合胞体ウイルス感染症の処置のための組成物及び方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI501967B (zh) * 2010-12-16 2015-10-01 Janssen R&D Ireland 作為呼吸道融合病毒抗病毒劑之氮雜吲哚類
GB201119538D0 (en) * 2011-11-10 2011-12-21 Viral Ltd Pharmaceutical compounds
BR112015008325B1 (pt) * 2012-10-16 2022-01-25 Janssen Sciences Ireland Uc Compostos antivirais contra o rsv, seu uso e composição farmacêutica que os compreende
EP2997028A1 (en) * 2013-05-14 2016-03-23 F.Hoffmann-La Roche Ag Aza-oxo-indoles for the treatment and prophylaxis of respiratory syncytial virus infection

Also Published As

Publication number Publication date
WO2015022263A1 (en) 2015-02-19
JP2016530257A (ja) 2016-09-29
EP3033341A1 (en) 2016-06-22
US9670211B2 (en) 2017-06-06
JP6211195B2 (ja) 2017-10-11
EP3033341B1 (en) 2017-05-03
RU2016105970A (ru) 2017-09-19
CA2914529A1 (en) 2015-02-19
MX2016001855A (es) 2016-05-24
US20160229853A1 (en) 2016-08-11
BR112016002638A2 (pt) 2017-08-01

Similar Documents

Publication Publication Date Title
HK1222395A1 (zh) 用於治療和預防呼吸道合胞病毒感染的氮雜-氧代-吲哚
HK1246296A1 (zh) 多環氨基甲酰基吡啶酮化合物和其用於治療hiv感染的用途
HK1223615A1 (zh) 多環氨基甲酰基吡啶酮化合物和其用於治療 感染的用途
IL246252A0 (en) Diaminopyrimidyl derivative compounds, their compositions and methods of treatment
HK1222653A1 (zh) 新的用於治療和預防呼吸道合胞病毒感染的氮雜-氧代-吲哚
HK1222398A1 (zh) 治療伯克霍爾德氏菌感染症的組合物及方法
HK1220324A1 (zh) 用於治療血管緊張素相關疾病的方法、化合物和組合物
SG10201705899XA (en) Prevention & treatment of neuropathy
HK1220374A1 (zh) 用於治療碳氧血紅蛋白血症的組合物和方法
HK1208680A1 (zh) 治療和預防呼吸道合胞體病毒感染的新吲唑類化合物
EP2964185A4 (en) PREPARATIONS FOR TREATMENT OF SLEEP RELATED ATMOSPHERES
SG11201702766YA (en) Spiro-indolines for the treatment and prophylaxis of respiratory syncytial virus infection (rsv)
HK1222855A1 (zh) 新的用於治療和預防呼吸道合胞病毒感染的氮雜-氧代-吲哚
HK1222389A1 (zh) 肺病症和其他病症的治療
ZA201601626B (en) Treatment of gases
GB201303721D0 (en) Compositions for treatment of sleep disorders