HK1222180A1 - 用於生物樣品中的具有提高的性能的 測定 - Google Patents

用於生物樣品中的具有提高的性能的 測定

Info

Publication number
HK1222180A1
HK1222180A1 HK16110255.1A HK16110255A HK1222180A1 HK 1222180 A1 HK1222180 A1 HK 1222180A1 HK 16110255 A HK16110255 A HK 16110255A HK 1222180 A1 HK1222180 A1 HK 1222180A1
Authority
HK
Hong Kong
Prior art keywords
timp2
assays
biological samples
improved performance
performance
Prior art date
Application number
HK16110255.1A
Other languages
English (en)
Chinese (zh)
Inventor
．維賈延德蘭
．萬卡塔蘇巴勞
Original Assignee
Astute Medical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astute Medical Inc filed Critical Astute Medical Inc
Publication of HK1222180A1 publication Critical patent/HK1222180A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/38—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against protease inhibitors of peptide structure
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/577—Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies; monoclonal antibodies per se are classified with their corresponding antigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/81—Protease inhibitors
    • G01N2333/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • G01N2333/8146—Metalloprotease (E.C. 3.4.24) inhibitors, e.g. tissue inhibitor of metallo proteinase, TIMP

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
HK16110255.1A 2013-08-07 2016-08-29 用於生物樣品中的具有提高的性能的 測定 HK1222180A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361863073P 2013-08-07 2013-08-07
PCT/US2014/050195 WO2015021308A1 (en) 2013-08-07 2014-08-07 Assays for timp2 having improved performance in biological samples

Publications (1)

Publication Number Publication Date
HK1222180A1 true HK1222180A1 (zh) 2017-06-23

Family

ID=52461941

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16110255.1A HK1222180A1 (zh) 2013-08-07 2016-08-29 用於生物樣品中的具有提高的性能的 測定

Country Status (12)

Country Link
US (2) US9879091B2 (de)
EP (2) EP3617234A1 (de)
JP (1) JP2016528236A (de)
KR (1) KR20160039682A (de)
CN (1) CN105531291A (de)
AU (1) AU2014305883A1 (de)
BR (1) BR112016002685A2 (de)
CA (1) CA2920521A1 (de)
EA (1) EA201690185A1 (de)
HK (1) HK1222180A1 (de)
MX (1) MX2016001573A (de)
WO (1) WO2015021308A1 (de)

Families Citing this family (13)

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EP3246707B1 (de) 2008-10-21 2020-09-30 Astute Medical, Inc. Verfahren und zusammensetzungen zur diagnose und prognose von nierenläsion und niereninsuffizienz
ES2592386T3 (es) 2009-12-20 2016-11-29 Astute Medical, Inc. Métodos y composiciones para el diagnóstico y pronóstico de lesión renal e insuficiencia renal
NZ605698A (en) 2010-06-23 2015-03-27 Astute Medical Inc Methods and compositions for diagnosis and prognosis of renal injury and renal failure
ES2933570T3 (es) 2011-12-08 2023-02-10 Astute Medical Inc Métodos y composiciones para el diagnóstico y el pronóstico de una lesión renal y de una insuficiencia renal
EP3734280B8 (de) 2013-01-17 2022-08-24 Astute Medical, Inc. Verfahren und zusammensetzungen zur diagnose und prognose von nierenläsion und niereninsuffizienz
US10300108B2 (en) 2013-12-03 2019-05-28 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
EP3281011B1 (de) 2015-04-09 2024-06-05 Astute Medical, Inc. Verfahren und zusammensetzungen zur diagnose und prognose von nierenläsion und niereninsuffizienz
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CN110352073A (zh) * 2016-10-28 2019-10-18 机敏医药股份有限公司 针对timp-2的抗体用于改善肾功能的用途
WO2018145117A1 (en) 2017-02-06 2018-08-09 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
EP3606554A4 (de) * 2017-04-05 2020-12-09 Astute Medical, Inc. Tests auf timp2 mit verbesserter leistung bei biologischen proben
US11435364B2 (en) 2018-05-24 2022-09-06 Renibus Therapeutics, Inc. Methods of treating patients at risk for renal injury and renal failure

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Also Published As

Publication number Publication date
EP3617234A1 (de) 2020-03-04
EP3030582A4 (de) 2017-05-17
EA201690185A1 (ru) 2016-07-29
AU2014305883A1 (en) 2016-02-25
US20180162953A1 (en) 2018-06-14
US10457744B2 (en) 2019-10-29
MX2016001573A (es) 2016-09-07
US20160297893A1 (en) 2016-10-13
CN105531291A (zh) 2016-04-27
EP3030582A1 (de) 2016-06-15
BR112016002685A2 (pt) 2018-01-30
CA2920521A1 (en) 2015-02-12
WO2015021308A1 (en) 2015-02-12
KR20160039682A (ko) 2016-04-11
US9879091B2 (en) 2018-01-30
JP2016528236A (ja) 2016-09-15

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