HK1221975A1 - 女生殖系幹細胞的分離 - Google Patents

女生殖系幹細胞的分離

Info

Publication number
HK1221975A1
HK1221975A1 HK16110078.6A HK16110078A HK1221975A1 HK 1221975 A1 HK1221975 A1 HK 1221975A1 HK 16110078 A HK16110078 A HK 16110078A HK 1221975 A1 HK1221975 A1 HK 1221975A1
Authority
HK
Hong Kong
Prior art keywords
isolation
stem cells
germline stem
female germline
female
Prior art date
Application number
HK16110078.6A
Other languages
English (en)
Inventor
L Tilly Jonathan
Johnson Joshua
Original Assignee
Massachusetts Gen Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Gen Hospital filed Critical Massachusetts Gen Hospital
Publication of HK1221975A1 publication Critical patent/HK1221975A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0608—Germ cells
    • C12N5/0611—Primordial germ cells, e.g. embryonic germ cells [EG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/42—Gynaecological or obstetrical instruments or methods
    • A61B17/425—Gynaecological or obstetrical instruments or methods for reproduction or fertilisation
    • A61B17/43—Gynaecological or obstetrical instruments or methods for reproduction or fertilisation for artificial insemination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16—Masculine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0608—Germ cells
    • C12N5/0609—Oocytes, oogonia
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/11—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from blood or immune system cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Reproductive Health (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Pregnancy & Childbirth (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK16110078.6A 2004-05-17 2016-08-24 女生殖系幹細胞的分離 HK1221975A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US57222204P 2004-05-17 2004-05-17
US57418704P 2004-05-24 2004-05-24
US58664104P 2004-07-09 2004-07-09

Publications (1)

Publication Number Publication Date
HK1221975A1 true HK1221975A1 (zh) 2017-06-16

Family

ID=35428927

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16110078.6A HK1221975A1 (zh) 2004-05-17 2016-08-24 女生殖系幹細胞的分離

Country Status (14)

Country Link
US (7) US20060010509A1 (zh)
EP (5) EP3498827A1 (zh)
JP (3) JP2008512989A (zh)
AU (3) AU2005252636A1 (zh)
CA (6) CA2566851C (zh)
CY (1) CY1116768T1 (zh)
DK (1) DK1765085T3 (zh)
ES (1) ES2547953T3 (zh)
HK (1) HK1221975A1 (zh)
HU (1) HUE027620T2 (zh)
PL (1) PL1765085T3 (zh)
PT (1) PT1765085E (zh)
SI (1) SI1765085T1 (zh)
WO (3) WO2005121321A2 (zh)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7955846B2 (en) 2004-05-17 2011-06-07 The General Hospital Corporation Compositions comprising female germline stem cells and methods of use thereof
AU2005252636A1 (en) 2004-05-17 2005-12-22 The General Hospital Corporation Compositions comprising female germline stem cells and methods of use thereof
US20080050814A1 (en) * 2006-06-05 2008-02-28 Cryo-Cell International, Inc. Procurement, isolation and cryopreservation of fetal placental cells
US20080064098A1 (en) * 2006-06-05 2008-03-13 Cryo-Cell International, Inc. Procurement, isolation and cryopreservation of maternal placental cells
WO2007142651A1 (en) * 2006-06-09 2007-12-13 Caritas St. Elizabeth Medical Center Of Boston, Inc. Methods and compositions for the treatment of neuropathy
CZ299271B6 (cs) * 2007-03-14 2008-06-04 Ceská zemedelská univerzita v Praze Použití inhibitoru histon deacetylázy pro prípravu kultivacního média na prodloužení životnosti savcích oocytu in vitro
EP2178550A4 (en) * 2007-07-27 2010-08-04 Immuneregen Biosciences Inc METHODS AND COMPOSITIONS FOR STIMULATING THE PROLIFERATION OR DIFFERENTIATION OF STEM CELLS BY SUBSTANCE P OR AN ANALOGUE THEREOF
EP2022847A1 (en) * 2007-08-07 2009-02-11 Irma Virant-Klun Pluripotent stem cells, methods for their isolation and their use and culture media
EP2176399A1 (en) * 2007-08-07 2010-04-21 PrimeGen Biotech LLC Isolation, characterization and propagation of germline stem cells
WO2009042127A2 (en) * 2007-09-24 2009-04-02 The General Hospital Corporation Compositions and methods for rescuing fertility
CA2832336C (en) 2011-04-14 2016-08-09 The General Hospital Corporation Compositions and methods for autologous germline mitochondrial energy transfer
CA2847292A1 (en) 2011-06-29 2013-01-03 The General Hospital Corporation Compositions and methods for enhancing bioenergetic status in female germ cells
CN102250830B (zh) * 2011-07-05 2013-01-16 西北农林科技大学 一种雌性生殖干细胞的体外分离及培养方法
US10271876B2 (en) * 2011-11-23 2019-04-30 Mezadata Medical Ip Holding Llc Method of in vitro fertilization with delay of embryo transfer and use of peripheral blood mononuclear cells
US20160237402A1 (en) * 2013-10-07 2016-08-18 Northeastern University Methods and Compositions for Ex Vivo Generation of Developmentally Competent Eggs from Germ Line Cells Using Autologous Cell Systems
EP3122366A4 (en) * 2014-03-27 2017-11-15 Jonathan Lee Tilly Methods for growth and maturation of ovarian follicles
CR20170067A (es) 2014-09-16 2017-05-10 Ovascience Inc Anticuerpos anti-vasa y metodos de producción y uso de los mismos
US11773368B2 (en) * 2015-09-17 2023-10-03 National Agriculture And Food Research Organization Culture method for differentiating primordial germ cells into functionally mature oocytes
JP6754966B2 (ja) * 2016-02-25 2020-09-16 国立大学法人広島大学 始原生殖細胞の培養方法及び始原生殖細胞の培養用培地添加物
MX2018016055A (es) * 2016-06-23 2019-07-04 Tithon Biotech Inc Células que expresan receptor de hormona paratiroidea 1 y usos de las mismas.
JP7021828B2 (ja) * 2017-11-10 2022-02-17 一公 川島 卵巣由来幹細胞の減数分裂誘導法
CN113355386B (zh) * 2021-06-02 2022-05-17 福建省妇幼保健院 一种应用三原核受精卵检测体外受精环境质量的方法
JP2024522861A (ja) * 2021-06-25 2024-06-21 ザ ジェイ． デビッド グラッドストーン インスティテューツ、 ア テスタメンタリー トラスト エスタブリッシュド アンダー ザ ウィル オブ ジェイ． デビッド グラッドストーン 始原生殖細胞
WO2024128499A1 (ko) * 2022-12-13 2024-06-20 (주)차바이오텍 탯줄 유래 부착형 줄기세포를 포함하는 난소부전 예방 또는 치료용 약학적 조성물

Family Cites Families (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3854470A (en) 1973-11-23 1974-12-17 L Augspurger Reproduction processes for cellular bodies
IT1057895B (it) 1975-02-17 1982-03-30 Serono Lab Gonadotropina corionica umana parzialmente desalinizzata per indurre l'ouvulazione
US4193392A (en) 1977-09-23 1980-03-18 Barnett Gordon R Method for removing ova from animals
US4326505A (en) 1980-01-07 1982-04-27 Occidental Petroleum Corporation Surgical procedure for embryo transplants on animals
US4339434A (en) 1981-08-17 1982-07-13 Gametrics Limited Method of increasing the incidence of female offspring
US4845077A (en) 1984-04-03 1989-07-04 Serono Laboratories, Inc. Method of inducing ovulation
FR2563726B1 (fr) 1984-05-04 1986-10-10 Robert Cassou Appareil d'insemination artificielle, notamment des carnivores
US4642094A (en) 1984-05-29 1987-02-10 North Jr Walter L Non-surgical embryo transfer device
US4589402A (en) 1984-07-26 1986-05-20 Serono Laboratories, Inc. Method of in vitro fertilization
US4725579A (en) 1985-02-21 1988-02-16 Serono Laboratories, Inc. Method of in vitro fertilization by a unique combination of gonadotropins
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
FR2580933B1 (fr) 1985-04-24 1987-08-07 Lenck Lucien Capacite trans-uterine pour fecondation " in vitro in vivo "
FR2589879B1 (fr) 1985-11-08 1989-05-12 Claude Ranoux Conteneur pour culture anaerobie d'embryons humains
AT387718B (de) 1986-04-09 1989-03-10 Fischl Franz H Dr Katheder zur kuenstlichen befruchtung
FR2608037A1 (fr) 1986-12-10 1988-06-17 Lenck Lucien Methode d'intubation destinee a permettre la transplantation de l'oeuf ou de la matiere embryonnaire, et moyens pour sa mise en oeuvre
FR2609885B1 (fr) 1987-01-22 1989-04-14 Cassou Robert Instrument pour l'insemination artificielle, le transfert d'embryons ou le prelevement de liquides folliculaires chez les mammiferes
US5538948A (en) 1987-01-30 1996-07-23 Novo Nordisk A/S Method for treating infertility comprising administering GnRH analog, gonadotrophins, and growth hormone
US4865589A (en) 1987-04-22 1989-09-12 Ludwig Simmet Instrument for the transfer of materials such as sperm and embryos
FR2614626B1 (fr) 1987-04-30 1989-07-21 Ranoux Claude Conteneur pour fecondation des ovocytes et replacement des embryons chez l'homme et l'animal
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
US5160312A (en) 1990-02-09 1992-11-03 W. R. Grace & Co.-Conn. Cryopreservation process for direct transfer of embryos
US5147315A (en) 1990-04-06 1992-09-15 C. R. Bard, Inc. Access catheter and system for use in the female reproductive system
US5627066A (en) 1991-05-14 1997-05-06 Mount Sinai School Of Medicine Of The City University Of New York Method and apparatus for in vitro fertilization
EP0585349A4 (en) 1991-05-14 1994-12-07 Sinai School Medicine METHOD AND APPARATUS FOR IN-VITRO FERTILIZATION.
FR2678506B1 (fr) 1991-07-01 2000-03-10 Claude Ranoux Procede de fecondation en cycle spontane.
US5851832A (en) 1991-07-08 1998-12-22 Neurospheres, Ltd. In vitro growth and proliferation of multipotent neural stem cells and their progeny
US5750376A (en) 1991-07-08 1998-05-12 Neurospheres Holdings Ltd. In vitro growth and proliferation of genetically modified multipotent neural stem cells and their progeny
US5744366A (en) 1992-05-01 1998-04-28 Trustees Of The University Of Pennsylvania Mesoscale devices and methods for analysis of motile cells
US5296375A (en) 1992-05-01 1994-03-22 Trustees Of The University Of Pennsylvania Mesoscale sperm handling devices
US5453357A (en) 1992-10-08 1995-09-26 Vanderbilt University Pluripotential embryonic stem cells and methods of making same
GB9227123D0 (en) 1992-12-30 1993-02-24 Applied Research Systems Method
US5563059A (en) 1993-02-23 1996-10-08 Genentech, Inc. Use of human inhibin and human activin to increase the number of mature primate oocytes
GB9305984D0 (en) 1993-03-23 1993-05-12 Royal Free Hosp School Med Predictive assay
US5360389A (en) 1993-05-25 1994-11-01 Chenette Philip E Methods for endometrial implantation of embryos
US5541081A (en) 1994-03-22 1996-07-30 President And Fellows Of Harvard College Process for assessing oocyte and embryo quality
GB9410639D0 (en) 1994-05-27 1994-07-13 Queen Mary & Westfield College Method of improving fertilization
JP3660026B2 (ja) 1995-09-04 2005-06-15 扶桑薬品工業株式会社 体外受精用培地組成物
US5827174A (en) 1995-09-26 1998-10-27 Reuss, Jr.; William Alexander Biological speciman containment and incubation pouch
US5854033A (en) 1995-11-21 1998-12-29 Yale University Rolling circle replication reporter systems
US6040340A (en) 1996-05-07 2000-03-21 Schering Aktiengesellschaft Implantation rates after in vitro fertilization, treatment of infertility and early pregnancy loss with a nitric oxide donor alone or in combination with progesterone, and a method for contraception with nitric oxide inhibitors
US5824548A (en) 1996-05-29 1998-10-20 Wisconsin Alumni Research Foundation Method of increasing survival of cultured primate embryos in medium containing exogenous gonadotrophin releasor hormone
US6251665B1 (en) 1997-02-07 2001-06-26 Cem Cezayirli Directed maturation of stem cells and production of programmable antigen presenting dentritic cells therefrom
CA2199663C (en) 1997-03-11 2004-08-10 Ruth Miriam Moses In vitro maturation and fertilization of mammalian oocytes
US5935968A (en) 1997-03-17 1999-08-10 Merck & Co., Inc. Methods for treating polycystic ovary syndrome
US5961444A (en) 1997-10-17 1999-10-05 Medworks Corporation In vitro fertilization procedure using direct vision
US6010448A (en) 1997-10-17 2000-01-04 Medworks Corp Embryo transfer arrangement
US6196965B1 (en) 1998-05-21 2001-03-06 Cryofacets, Inc. Compositions methods and devices for embryo implantation for in vitro fertilization
US6485972B1 (en) 1998-10-15 2002-11-26 President And Fellows Of Harvard College WNT signalling in reproductive organs
EP1156822B1 (en) 1999-02-24 2006-02-08 Novo Nordisk A/S Iin vitro method for synchronisation of oocyte maturation
DE60034662T2 (de) 1999-02-24 2008-01-03 Novo Nordisk A/S Behandlung von unfruchtbarkeit
JP2003512833A (ja) 1999-10-27 2003-04-08 マウント・シナイ・ホスピタル 卵細胞及び接合子の発育能力を強化するための方法及び組成物
US6875854B1 (en) * 1999-11-18 2005-04-05 The Brigham And Women's Hospital, Inc. Compositions and methods for the improved diagnosis and treatment of germ cell tumors
EP1233978A4 (en) 1999-11-18 2003-07-23 Brigham & Womens Hospital COMPOSITIONS AND METHODS FOR IMPROVED DIAGNOSIS AND TREATMENT OF GERM CELL TUMORS
US6544166B1 (en) 1999-11-25 2003-04-08 Groendahl Christian Treatment of human infertility
US20020142457A1 (en) 1999-12-28 2002-10-03 Akihiro Umezawa Cell having the potentiality of differentiation into cardiomyocytes
US6395546B1 (en) 2000-02-01 2002-05-28 Neurogeneration, Inc. Generation of dopaminergic neurons from human nervous system stem cells
FR2812004B1 (fr) 2000-07-24 2002-12-27 Ccd Lab Milieux de culture pour fecondation in vitro, ou pour la culture de follicules, cellules germinales males ou embryons
EP1443106A4 (en) 2001-11-06 2005-04-27 Univ Shanghai 2Nd Medical EMBRYONIC STEM CELLS DERIVED FROM SOMATIC CELLS, AND DIFFERENTIATED CELLS THEREOF
AUPR892501A0 (en) 2001-11-16 2001-12-13 Peter Maccallum Cancer Institute, The Method of enhancing self renewal of stem cells and uses thereof
US20030134422A1 (en) 2002-01-16 2003-07-17 Sayre Chauncey Bigelow Stem cell maturation for all tissue lines
US7390659B2 (en) 2002-07-16 2008-06-24 The Trustees Of Columbia University In The City Of New York Methods for inducing differentiation of embryonic stem cells and uses thereof
AU2003247135A1 (en) 2002-07-23 2004-02-09 Nanodiagnostics, Inc. Embryonic stem cell markers and uses thereof
WO2005007687A1 (en) 2003-07-09 2005-01-27 Dana-Farber Cancer Institute, Inc Compositions and methods for modulating ovarian follicular initiation
US20050130302A1 (en) * 2003-09-29 2005-06-16 Reprocell Inc. Method and composition for regulating expansion of stem cells
AU2005252636A1 (en) 2004-05-17 2005-12-22 The General Hospital Corporation Compositions comprising female germline stem cells and methods of use thereof
US7955846B2 (en) * 2004-05-17 2011-06-07 The General Hospital Corporation Compositions comprising female germline stem cells and methods of use thereof
US20080050347A1 (en) * 2006-08-23 2008-02-28 Ichim Thomas E Stem cell therapy for cardiac valvular dysfunction
WO2008157398A1 (en) * 2007-06-13 2008-12-24 Litron Laboratories Ltd. Method for measuring in vivo hematotoxicity with an emphasis on radiation exposure assessment
US20090111764A1 (en) * 2007-10-25 2009-04-30 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Mitochondrial selection
CA2832336C (en) 2011-04-14 2016-08-09 The General Hospital Corporation Compositions and methods for autologous germline mitochondrial energy transfer

Also Published As

Publication number Publication date
AU2005252636A1 (en) 2005-12-22
EP1765985A2 (en) 2007-03-28
EP1765085A4 (en) 2008-11-12
CA2566857A1 (en) 2005-12-01
EP2987855A1 (en) 2016-02-24
ES2547953T3 (es) 2015-10-09
CA2569031A1 (en) 2006-01-05
EP3498827A1 (en) 2019-06-19
JP2007537754A (ja) 2007-12-27
PL1765085T3 (pl) 2015-11-30
CA2841716A1 (en) 2005-12-01
CA3009909A1 (en) 2005-12-22
CY1116768T1 (el) 2017-03-15
WO2006001938A2 (en) 2006-01-05
US9267111B2 (en) 2016-02-23
HUE027620T2 (en) 2016-10-28
WO2005113752A2 (en) 2005-12-01
WO2005113752A3 (en) 2007-06-07
US20160362657A1 (en) 2016-12-15
PT1765085E (pt) 2015-10-20
EP1765985A4 (en) 2008-10-15
US20190352602A1 (en) 2019-11-21
US20160137978A1 (en) 2016-05-19
CA2566851C (en) 2015-11-10
US20060015961A1 (en) 2006-01-19
US20120195861A1 (en) 2012-08-02
EP1765085A2 (en) 2007-03-28
DK1765085T3 (en) 2015-10-05
EP2987855B1 (en) 2018-11-21
JP2008512990A (ja) 2008-05-01
AU2005257839A1 (en) 2006-01-05
CA2566851A1 (en) 2005-12-22
US20060010509A1 (en) 2006-01-12
EP1765983A4 (en) 2008-10-22
AU2005245899A1 (en) 2005-12-01
CA2841716C (en) 2020-01-07
JP2008512989A (ja) 2008-05-01
WO2006001938A3 (en) 2006-10-12
EP1765983A2 (en) 2007-03-28
WO2005121321A2 (en) 2005-12-22
EP1765085B1 (en) 2015-07-08
US20190300852A1 (en) 2019-10-03
SI1765085T1 (sl) 2015-11-30
CA2897658A1 (en) 2005-12-22
WO2005121321A3 (en) 2006-09-28

Similar Documents

Publication Publication Date Title
HK1221975A1 (zh) 女生殖系幹細胞的分離
HK1219295A1 (zh) 衍生胚胎幹細胞
GB2441530B (en) Stem Cells
HK1225753A1 (zh) 使用胎盤幹細胞的免疫調節
GB2432835B (en) Culturing human embryonic stem cells
EP1838874A4 (en) METHODS FOR REGULATING THE ACTIVITY OF STEM CELLS
HK1223248A1 (zh) 吸脂後脂肪吸取物分離及純化造血幹細胞
SG138570A1 (en) Growth of embryonic stem cells
EP1809740A4 (en) CARDIAC STEM CELLS
EP2007874A4 (en) PROPAGATION OF PRIMARY CELLS
EP1917348A4 (en) ISOLATION OF MULTIPLE LINE STEM CELLS
EP2076587A4 (en) ISOLATION, EXPANSION AND USE OF TUMOR STEM CELLS
GB2429211B (en) Feeder independent extended culture of embryonic stem cells
EP1627912A4 (en) PREPARATION OF ENDODERMAL STEM CELLS
SG120145A1 (en) Isolation structure with nitrogen-containing linerand methods of manufacture
EP1766389A4 (en) CELL ISOLATION PROCEDURE
EP1870623A4 (en) ARRANGEMENT ARISING FROM A PLUG AND RECORDING COMPONENT
GB2445701B (en) Assembly of male and female members
GB201002469D0 (en) Parthenote-derived stem cells and methods of making and using them
GB0426182D0 (en) Photoporation of cells
GB2425889B (en) Shallow trench isolation process and structure
GB2426765B (en) The preparation of multipotent stem cells
ZA200803930B (en) Immunomodulation using placental stem cells
EP1954801A4 (en) METHOD FOR ISOLATING CELLS
GB0412861D0 (en) Screening of stem cells

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20230523