EP1233978A4 - Compositions and methods for the improved diagnosis and treatment of germ cell tumors - Google Patents

Compositions and methods for the improved diagnosis and treatment of germ cell tumors

Info

Publication number
EP1233978A4
EP1233978A4 EP00980428A EP00980428A EP1233978A4 EP 1233978 A4 EP1233978 A4 EP 1233978A4 EP 00980428 A EP00980428 A EP 00980428A EP 00980428 A EP00980428 A EP 00980428A EP 1233978 A4 EP1233978 A4 EP 1233978A4
Authority
EP
European Patent Office
Prior art keywords
compositions
treatment
methods
germ cell
cell tumors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP00980428A
Other languages
German (de)
French (fr)
Other versions
EP1233978A1 (en
Inventor
Diego H Castrillon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Brigham and Womens Hospital Inc
Original Assignee
Brigham and Womens Hospital Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Brigham and Womens Hospital Inc filed Critical Brigham and Womens Hospital Inc
Publication of EP1233978A1 publication Critical patent/EP1233978A1/en
Publication of EP1233978A4 publication Critical patent/EP1233978A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
EP00980428A 1999-11-18 2000-11-16 Compositions and methods for the improved diagnosis and treatment of germ cell tumors Withdrawn EP1233978A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16639499P 1999-11-18 1999-11-18
US166394P 1999-11-18
PCT/US2000/031485 WO2001036445A1 (en) 1999-11-18 2000-11-16 Compositions and methods for the improved diagnosis and treatment of germ cell tumors

Publications (2)

Publication Number Publication Date
EP1233978A1 EP1233978A1 (en) 2002-08-28
EP1233978A4 true EP1233978A4 (en) 2003-07-23

Family

ID=22603115

Family Applications (1)

Application Number Title Priority Date Filing Date
EP00980428A Withdrawn EP1233978A4 (en) 1999-11-18 2000-11-16 Compositions and methods for the improved diagnosis and treatment of germ cell tumors

Country Status (2)

Country Link
EP (1) EP1233978A4 (en)
WO (1) WO2001036445A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2566857A1 (en) 2004-05-17 2005-12-01 The General Hospital Corporation Methods and compositions for producing germ cells from peripheral blood derived germline stem cells
US7955846B2 (en) 2004-05-17 2011-06-07 The General Hospital Corporation Compositions comprising female germline stem cells and methods of use thereof
US8647869B2 (en) 2011-04-14 2014-02-11 The General Hospital Corporation Compositions and methods for autologous germline mitochondrial energy transfer
US9845482B2 (en) 2011-06-29 2017-12-19 The General Hospital Corporation Compositions and methods for enhancing bioenergetic status in female germ cells
WO2016044436A2 (en) 2014-09-16 2016-03-24 Ovascience, Inc. Anti-vasa antibodies, and methods of production and use thereof
CA2971361A1 (en) * 2014-12-24 2016-06-30 Pierre Fabre Medicament Novel humanized adam17 antibody

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
CASTRILLON DIEGO H ET AL: "The human VASA gene is specifically expressed in the germ cell lineage.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES, vol. 97, no. 17, 15 August 2000 (2000-08-15), August 15, 2000, pages 9585 - 9590, XP002241902, ISSN: 0027-8424 *
GRUIDL M E ET AL: "MULTIPLE POTENTIAL GERM-LINE HELICASES ARE COMPONENTS OF THE GERM-LINE-SPECIFIC P GRANULES OF CAENORHABDITIS ELEGANS", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 93, November 1996 (1996-11-01), pages 13837 - 13842, XP001040807, ISSN: 0027-8424 *
KOMIYA TOHRU ET AL: "Cloning of a gene of the dead box protein family which is specifically expressed in germ cells in rats.", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 207, no. 1, 1995, pages 405 - 410, XP002241905, ISSN: 0006-291X *
MOCHIZUKI KAZUFUMI ET AL: "Universal occurrence of the vasa-related genes among metazoans and their germline expression in Hydra.", DEVELOPMENT GENES AND EVOLUTION, vol. 211, no. 6, 2001, pages 299 - 308, XP002241901, ISSN: 0949-944X *
OLSEN LISBETH CHARLOTTE ET AL: "A vasa-like gene in zebrafish identifies putative primordial germ cells.", MECHANISMS OF DEVELOPMENT, vol. 66, no. 1-2, 1997, pages 95 - 105, XP002241904, ISSN: 0925-4773 *
See also references of WO0136445A1 *
YOON CHRISTINA ET AL: "Zebrafish vasa homologue RNA is localized to the cleavage planes of 2- and 4-cell-stage embryos and is expressed in the primordial germ cells.", DEVELOPMENT (CAMBRIDGE), vol. 124, no. 16, 1997, pages 3157 - 3165, XP002241903, ISSN: 0950-1991 *
YUKO FUJIWARA ET AL: "ISOLATION OF A DEAD-FAMILY PROTEIN GENE THAT ENCODES A MURINE HOMOLOG OF DROSOPHILA VASA AND ITS SPECIFIC EXPRESSION IN GERM CELLLINEAGE", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 91, no. 25, 6 December 1994 (1994-12-06), pages 12258 - 12262, XP000570446, ISSN: 0027-8424 *
ZEEMAN ANNE-MARIE ET AL: "VASA is a specific marker for both normal and malignant human germ cells.", LABORATORY INVESTIGATION, vol. 82, no. 2, February 2002 (2002-02-01), February, 2002, pages 159 - 166, XP002241900, ISSN: 0023-6837 *

Also Published As

Publication number Publication date
WO2001036445A1 (en) 2001-05-25
EP1233978A1 (en) 2002-08-28

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 20020618

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Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

A4 Supplementary search report drawn up and despatched

Effective date: 20030606

STAA Information on the status of an ep patent application or granted ep patent

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18D Application deemed to be withdrawn

Effective date: 20030823