HK1221256A1 - 用於调节mir-122的微小rna化合物和方法 - Google Patents
用於调节mir-122的微小rna化合物和方法 Download PDFInfo
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- HK1221256A1 HK1221256A1 HK16109285.7A HK16109285A HK1221256A1 HK 1221256 A1 HK1221256 A1 HK 1221256A1 HK 16109285 A HK16109285 A HK 16109285A HK 1221256 A1 HK1221256 A1 HK 1221256A1
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- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
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| WO2015038059A1 (en) * | 2013-09-16 | 2015-03-19 | Välinge Innovation AB | An assembled product and a method of assembling the assembled product |
| US9994846B2 (en) | 2013-10-25 | 2018-06-12 | Regulus Therapeutics Inc. | MicroRNA compounds and methods for modulating miR-21 activity |
| EA201790771A1 (ru) * | 2014-11-10 | 2017-11-30 | Глаксосмитклайн Интеллекчуал Проперти (№2) Лимитед | Фармацевтические композиции длительного действия для лечения гепатита c |
| BR112017009504A2 (pt) | 2014-11-10 | 2018-02-06 | Glaxosmithkline Ip No 2 Ltd | métodos para tratar e para curar uma infecção por hcv, e, composição farmacêutica. |
| ES2989704T3 (es) * | 2015-11-06 | 2024-11-27 | Ionis Pharmaceuticals Inc | Compuestos antisentido conjugados para uso terapéutico |
| CN113952353A (zh) | 2015-11-06 | 2022-01-21 | Ionis制药公司 | 调节载脂蛋白(a)表达 |
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| JP7164521B2 (ja) | 2016-06-21 | 2022-11-01 | オリオン・オフサルモロジー・エルエルシー | 炭素環式プロリンアミド誘導体 |
| UA124672C2 (uk) | 2016-06-21 | 2021-10-27 | Оріон Офтальмолоджі Ллс | Гетероциклічні похідні пролінаміду |
| CA3011668A1 (en) | 2016-09-02 | 2018-03-08 | Arrowhead Pharmaceuticals, Inc. | Targeting ligands |
| JP2019535839A (ja) | 2016-11-29 | 2019-12-12 | ピュアテック ヘルス エルエルシー | 治療剤の送達のためのエクソソーム |
| JP7279081B2 (ja) * | 2018-05-08 | 2023-05-22 | レグルス セラピューティクス インコーポレイテッド | Mir-122を調節するためのマイクロrna化合物及び方法 |
| JP2021531278A (ja) * | 2018-07-20 | 2021-11-18 | レグルス セラピューティクス インコーポレイテッド | オリゴヌクレオチドの経口送達のための方法 |
| CN112843084A (zh) * | 2019-11-27 | 2021-05-28 | 中国人民解放军第四军医大学 | MiR-122-5p在制备促进创伤愈合药物中的应用 |
| CN114057816B (zh) * | 2020-07-30 | 2025-02-11 | 浙江柏拉阿图医药科技有限公司 | 富含腺嘌呤硫代磷酸酯化寡核苷酸及其抗肝炎病毒的应用 |
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| TW202320808A (zh) * | 2021-10-08 | 2023-06-01 | 美商雷格勒斯治療公司 | 用於治療多囊性腎病之方法及組合物 |
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| SG11201508925WA (en) | 2015-11-27 |
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| NZ732101A (en) | 2022-02-25 |
| MX2015014816A (es) | 2016-03-09 |
| US10150967B2 (en) | 2018-12-11 |
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