HK1220236A1 - 使用纳米粒子辅助信号放大的rna微芯片检测 - Google Patents

使用纳米粒子辅助信号放大的rna微芯片检测 Download PDF

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Publication number
HK1220236A1
HK1220236A1 HK16108342.0A HK16108342A HK1220236A1 HK 1220236 A1 HK1220236 A1 HK 1220236A1 HK 16108342 A HK16108342 A HK 16108342A HK 1220236 A1 HK1220236 A1 HK 1220236A1
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HK
Hong Kong
Prior art keywords
rna
chimeric
probe
label
probes
Prior art date
Application number
HK16108342.0A
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English (en)
Chinese (zh)
Inventor
Huang Zhen
Original Assignee
Georgia State University Research Foundation, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Georgia State University Research Foundation, Inc. filed Critical Georgia State University Research Foundation, Inc.
Publication of HK1220236A1 publication Critical patent/HK1220236A1/zh

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Virology (AREA)
HK16108342.0A 2013-04-04 2014-04-04 使用纳米粒子辅助信号放大的rna微芯片检测 HK1220236A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361808447P 2013-04-04 2013-04-04
US61/808,447 2013-04-04
PCT/US2014/033062 WO2014165814A1 (en) 2013-04-04 2014-04-04 Rna microchip detection using nanoparticle-assisted signal amplification

Publications (1)

Publication Number Publication Date
HK1220236A1 true HK1220236A1 (zh) 2017-04-28

Family

ID=51023017

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16108342.0A HK1220236A1 (zh) 2013-04-04 2014-04-04 使用纳米粒子辅助信号放大的rna微芯片检测

Country Status (7)

Country Link
US (1) US20160068894A1 (enExample)
EP (1) EP2981622A1 (enExample)
JP (1) JP2016515827A (enExample)
KR (1) KR20150139582A (enExample)
CN (1) CN105283561A (enExample)
HK (1) HK1220236A1 (enExample)
WO (1) WO2014165814A1 (enExample)

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* Cited by examiner, † Cited by third party
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EP3256601B1 (en) 2015-02-11 2021-04-07 Biogen MA Inc. Methods for detecting therapeutic nucleic acids
US10472666B2 (en) 2016-02-15 2019-11-12 Roche Sequencing Solutions, Inc. System and method for targeted depletion of nucleic acids
EP3417071B1 (en) * 2016-02-15 2023-04-05 F. Hoffmann-La Roche AG System and method for targeted depletion of nucleic acids
CN109997042B (zh) * 2016-09-22 2022-08-19 高丽大学校产学协力团 纳米等离子生物传感器和使用其检测疾病标志物的方法
CN107828861B (zh) * 2017-11-21 2021-06-04 湖南工程学院 基于微流控芯片和g-四链体-血红素dna酶检测循环核酸用试剂盒及其制备方法和应用
AU2021231104B2 (en) * 2020-03-03 2025-02-20 Universiteit Gent Hydrolysis-based probe and method for STR genotyping
CN118957050A (zh) * 2022-04-01 2024-11-15 海南医学院 一种登革病毒ns1基因片段裸眼检测平台在制备登革病毒感染筛查的试剂盒中的应用
CN116004765B (zh) * 2022-08-09 2025-11-21 合肥工业大学 一种功能性核酸探针及其制备方法与应用
WO2024130098A1 (en) * 2022-12-16 2024-06-20 Cz Biohub Sf, Llc Microbeads with ratiometric lanthanide encoding for drug screening
KR102667684B1 (ko) * 2023-07-10 2024-06-10 한국화학연구원 형광이 표지된 유전자 프로브의 형광 신호를 증폭하는 은나노 산화아연 복합 나노구조체, 이의 제조방법 및 형광신호 검출방법

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE68929361T2 (de) 1988-04-27 2002-06-20 Isis Pharmaceuticals, Inc. Oligoribonukleotid-Derivate und Verwendung davon als Antiviral Arzneimittel
US5198543A (en) 1989-03-24 1993-03-30 Consejo Superior Investigaciones Cientificas PHI29 DNA polymerase
US5001050A (en) 1989-03-24 1991-03-19 Consejo Superior Investigaciones Cientificas PHφ29 DNA polymerase
US5871928A (en) 1989-06-07 1999-02-16 Fodor; Stephen P. A. Methods for nucleic acid analysis
AU7796491A (en) 1990-05-07 1991-11-27 Anchor Hocking Corporation A composite closure, disk and package
DE4216134A1 (de) 1991-06-20 1992-12-24 Europ Lab Molekularbiolog Synthetische katalytische oligonukleotidstrukturen
JPH07501204A (ja) 1991-06-28 1995-02-09 マサチューセッツ インスティテュート オブ テクノロジー 局所的オリゴヌクレオチド療法
IL108206A0 (en) 1993-01-06 1994-04-12 Univ Johns Hopkins Oligomers having improved stability at acid ph
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WO1995023225A2 (en) 1994-02-23 1995-08-31 Ribozyme Pharmaceuticals, Inc. Method and reagent for inhibiting the expression of disease related genes
US5604097A (en) 1994-10-13 1997-02-18 Spectragen, Inc. Methods for sorting polynucleotides using oligonucleotide tags
US5599695A (en) 1995-02-27 1997-02-04 Affymetrix, Inc. Printing molecular library arrays using deprotection agents solely in the vapor phase
EP1102977A1 (en) 1998-08-08 2001-05-30 Imperial Cancer Research Technology Limited Fluorescence assay for biological systems
JP2000300267A (ja) * 1999-04-21 2000-10-31 Technol Res Assoc Of Medical & Welfare Apparatus 核酸の測定方法及びそのためのキット
WO2009120557A2 (en) * 2008-03-26 2009-10-01 Indevr, Inc. Nanoparticle-mediated signal amplification
WO2011049964A1 (en) * 2009-10-19 2011-04-28 Lab Scientific Group Rna detection and quantitation

Also Published As

Publication number Publication date
CN105283561A (zh) 2016-01-27
JP2016515827A (ja) 2016-06-02
EP2981622A1 (en) 2016-02-10
US20160068894A1 (en) 2016-03-10
WO2014165814A1 (en) 2014-10-09
KR20150139582A (ko) 2015-12-11

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