HK1217499A1 - 蛋白的多聚形式 - Google Patents
蛋白的多聚形式Info
- Publication number
- HK1217499A1 HK1217499A1 HK16105402.3A HK16105402A HK1217499A1 HK 1217499 A1 HK1217499 A1 HK 1217499A1 HK 16105402 A HK16105402 A HK 16105402A HK 1217499 A1 HK1217499 A1 HK 1217499A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- nox
- proteins
- polymeric forms
- polymeric
- forms
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/795—Porphyrin- or corrin-ring-containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/41—Porphyrin- or corrin-ring-containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N2005/1092—Details
- A61N2005/1098—Enhancing the effect of the particle by an injected agent or implanted device
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- Urology & Nephrology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Radiology & Medical Imaging (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Neurosurgery (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US2013/020602 WO2014107171A1 (en) | 2013-01-07 | 2013-01-07 | Polymeric forms of h-nox proteins |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1217499A1 true HK1217499A1 (zh) | 2017-01-13 |
Family
ID=51062401
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK16105402.3A HK1217499A1 (zh) | 2013-01-07 | 2016-05-11 | 蛋白的多聚形式 |
Country Status (10)
Country | Link |
---|---|
US (5) | US10385116B2 (zh) |
EP (2) | EP2941440B1 (zh) |
JP (1) | JP6322652B2 (zh) |
CN (2) | CN105408354B (zh) |
AU (3) | AU2013204158B2 (zh) |
CA (1) | CA2897018C (zh) |
ES (1) | ES2886531T3 (zh) |
HK (1) | HK1217499A1 (zh) |
NZ (1) | NZ709825A (zh) |
WO (1) | WO2014107171A1 (zh) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105408354B (zh) | 2013-01-07 | 2020-09-18 | 欧姆尼奥克斯公司 | H-nox蛋白的多聚形式 |
WO2014193963A1 (en) * | 2013-05-28 | 2014-12-04 | The Johns Hopkins University | Controlled outgassing of hyberbarically loaded materials for the delivery of oxygen and other therapeutic gases in biomedical applications |
CA2979974A1 (en) * | 2015-03-17 | 2016-09-22 | Omniox, Inc. | Modulation of tumor immunity by protein-mediated o2 delivery |
CN109072194B (zh) | 2015-12-09 | 2022-12-27 | 纪念斯隆-凯特林癌症中心 | 免疫细胞组合物及其使用方法 |
CA3014651A1 (en) * | 2016-02-16 | 2017-08-24 | Omniox, Inc. | Modulation of hypoxia associated with stroke |
WO2018044866A1 (en) | 2016-08-30 | 2018-03-08 | Memorial Sloan Kettering Cancer Center | Immune cell compositions and methods of use for treating viral and other infections |
GB201702863D0 (en) * | 2017-02-22 | 2017-04-05 | Evox Therapeutics Ltd | Improved loading of EVs with therapeutic proteins |
IL280536B1 (en) * | 2018-08-02 | 2024-08-01 | Dyne Therapeutics Inc | Muscle oriented clasps and their uses |
EP3836911A1 (en) * | 2018-08-15 | 2021-06-23 | Omniox, Inc. | H-nox proteins for treating cardiovascular and pulmonary conditions |
KR20220032568A (ko) | 2019-06-25 | 2022-03-15 | 길리애드 사이언시즈, 인코포레이티드 | Flt3l-fc 융합 단백질 및 사용 방법 |
KR20220085796A (ko) | 2019-10-18 | 2022-06-22 | 포티 세븐, 인코포레이티드 | 골수이형성 증후군 및 급성 골수성 백혈병을 치료하기 위한 조합 치료 |
US20210147568A1 (en) | 2019-10-31 | 2021-05-20 | Forty Seven, Inc. | Anti-cd47 based treatment of blood cancer |
TWI778443B (zh) | 2019-11-12 | 2022-09-21 | 美商基利科學股份有限公司 | Mcl1抑制劑 |
EP4081305B1 (en) | 2019-12-24 | 2024-09-18 | Carna Biosciences, Inc. | Diacylglycerol kinase modulating compounds |
CN115087488A (zh) | 2020-02-14 | 2022-09-20 | 震动疗法股份有限公司 | 与ccr8结合的抗体和融合蛋白及其用途 |
AU2021264550A1 (en) | 2020-05-01 | 2022-11-17 | Gilead Sciences, Inc. | CD73 inhibiting 2,4-dioxopyrimidine compounds |
JP6974808B1 (ja) * | 2021-02-10 | 2021-12-01 | 株式会社タンガロイ | 切削インサート |
TW202302145A (zh) | 2021-04-14 | 2023-01-16 | 美商基利科學股份有限公司 | CD47/SIRPα結合及NEDD8活化酶E1調節次單元之共抑制以用於治療癌症 |
WO2022245671A1 (en) | 2021-05-18 | 2022-11-24 | Gilead Sciences, Inc. | Methods of using flt3l-fc fusion proteins |
EP4359411A1 (en) | 2021-06-23 | 2024-05-01 | Gilead Sciences, Inc. | Diacylglyercol kinase modulating compounds |
KR20240025616A (ko) | 2021-06-23 | 2024-02-27 | 길리애드 사이언시즈, 인코포레이티드 | 다이아실글리세롤 키나제 조절 화합물 |
EP4359415A1 (en) | 2021-06-23 | 2024-05-01 | Gilead Sciences, Inc. | Diacylglyercol kinase modulating compounds |
AU2022297367A1 (en) | 2021-06-23 | 2023-12-07 | Gilead Sciences, Inc. | Diacylglyercol kinase modulating compounds |
AU2022305241A1 (en) * | 2021-07-01 | 2024-01-25 | Bluebird Bio, Inc. | Methods |
KR20240091056A (ko) | 2021-10-28 | 2024-06-21 | 길리애드 사이언시즈, 인코포레이티드 | 피리디진-3(2h)-온 유도체 |
CA3239528A1 (en) | 2021-12-22 | 2023-06-29 | Gilead Sciences, Inc. | Ikaros zinc finger family degraders and uses thereof |
AU2022417491A1 (en) | 2021-12-22 | 2024-05-23 | Gilead Sciences, Inc. | Ikaros zinc finger family degraders and uses thereof |
TW202340168A (zh) | 2022-01-28 | 2023-10-16 | 美商基利科學股份有限公司 | Parp7抑制劑 |
EP4245756A1 (en) | 2022-03-17 | 2023-09-20 | Gilead Sciences, Inc. | Ikaros zinc finger family degraders and uses thereof |
US20230355796A1 (en) | 2022-03-24 | 2023-11-09 | Gilead Sciences, Inc. | Combination therapy for treating trop-2 expressing cancers |
TW202345901A (zh) | 2022-04-05 | 2023-12-01 | 美商基利科學股份有限公司 | 用於治療結腸直腸癌之組合療法 |
WO2023205719A1 (en) | 2022-04-21 | 2023-10-26 | Gilead Sciences, Inc. | Kras g12d modulating compounds |
US20240116928A1 (en) | 2022-07-01 | 2024-04-11 | Gilead Sciences, Inc. | Cd73 compounds |
US20240091351A1 (en) | 2022-09-21 | 2024-03-21 | Gilead Sciences, Inc. | FOCAL IONIZING RADIATION AND CD47/SIRPa DISRUPTION ANTICANCER COMBINATION THERAPY |
WO2024137852A1 (en) | 2022-12-22 | 2024-06-27 | Gilead Sciences, Inc. | Prmt5 inhibitors and uses thereof |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA138006A (en) | 1911-05-01 | 1912-01-23 | John G. Elbs | Egg carrier |
US4873192A (en) | 1987-02-17 | 1989-10-10 | The United States Of America As Represented By The Department Of Health And Human Services | Process for site specific mutagenesis without phenotypic selection |
US5248766A (en) | 1990-08-17 | 1993-09-28 | Baxter International Inc. | Oxirane-modified hemoglobin based composition |
US5776898A (en) | 1991-05-14 | 1998-07-07 | Dana-Farber Cancer Institute | Method for treating a tumor with a chemotherapeutic agent |
WO1992020369A1 (en) | 1991-05-14 | 1992-11-26 | Dana Farber Cancer Institute | Use of hemoglobin in a method for the treatment of tumors with chemotherapeutic agents |
AU735799C (en) | 1997-02-28 | 2005-04-28 | Regents Of The University Of California, The | Methods and compositions for optimisation of oxygen transport by cell-free systems |
US5981710A (en) | 1997-07-21 | 1999-11-09 | Baxter International, Inc. | Therapeutic hemoglobin composition having isotropically increased size |
US20030153491A1 (en) | 2002-01-11 | 2003-08-14 | Winslow Robert M. | Methods and compositions for oxygen transport comprising a high oxygen affinity modified hemoglobin |
EP1850852A4 (en) | 2005-02-22 | 2009-11-18 | Cedars Sinai Medical Center | USE OF SILDENAFIL, VARDENAFIL AND OTHER 5-PHOSPHODIESTERASE INHIBITORS TO INCREASE THE PERMEABILITY OF THE ABNORMAL BLOOD-BRAIN DISEASE |
PT1981519T (pt) | 2005-12-29 | 2018-02-23 | Dyax Corp | Inibição de protéases |
JP2009537145A (ja) * | 2006-05-15 | 2009-10-29 | バイラル ロジック システムズ テクノロジー コーポレーション | 免疫学的疾患および障害を治療するためのcd47と関連した組成物および方法 |
DK2463297T3 (en) * | 2006-05-22 | 2017-01-09 | Univ California | Oxygen Compositions and Methods |
US20110300113A1 (en) | 2006-09-19 | 2011-12-08 | Deutsches Krebsforschungszentrum | Death Receptor CD95 Controls Neurogenesis of Adult Neural Stem Cells in Vivo and in Vitro |
JP2010513405A (ja) | 2006-12-21 | 2010-04-30 | ノボ・ノルデイスク・エー/エス | 二量体プロラクチンレセプターリガンド |
US20110243849A1 (en) * | 2010-04-02 | 2011-10-06 | Marletta Michael A | Heme-binding photoactive polypeptides and methods of use thereof |
US8742073B2 (en) | 2010-05-27 | 2014-06-03 | Bing Lou Wong | Method for the preparation of a high-temperature stable oxygen-carrier-containing pharmaceutical composition and the use thereof |
US7989593B1 (en) | 2010-05-27 | 2011-08-02 | Bing Lou Wong | Method for the preparation of a high-temperature stable oxygen-carrier-containing pharmaceutical composition and the use thereof |
US20140363496A1 (en) | 2011-01-07 | 2014-12-11 | Vindico NanoBio Technology Inc. | Compositions and Methods for Inducing Nanoparticle-mediated Microvascular Embolization of Tumors |
PT2661275T (pt) | 2011-01-07 | 2019-04-24 | Poseida Therapeutics Inc | Composições e métodos para a entrega a tumores de agentes ligantes de elevada afinidade para o oxigénio |
US20130052232A1 (en) | 2011-08-31 | 2013-02-28 | Bing Lou Wong | Method for the preparation of a heat stable oxygen carrier-containing composition facilating beta-beta cross-linking |
CN105408354B (zh) | 2013-01-07 | 2020-09-18 | 欧姆尼奥克斯公司 | H-nox蛋白的多聚形式 |
AU2015358413A1 (en) | 2014-12-05 | 2017-06-29 | Poseida Therapeutics, Inc. | Compositions and methods for inducing nanoparticle-mediated microvascular embolization of tumors |
CA2979974A1 (en) * | 2015-03-17 | 2016-09-22 | Omniox, Inc. | Modulation of tumor immunity by protein-mediated o2 delivery |
CA3014651A1 (en) * | 2016-02-16 | 2017-08-24 | Omniox, Inc. | Modulation of hypoxia associated with stroke |
-
2013
- 2013-01-07 CN CN201380074345.5A patent/CN105408354B/zh active Active
- 2013-01-07 NZ NZ709825A patent/NZ709825A/en unknown
- 2013-01-07 EP EP13870254.3A patent/EP2941440B1/en active Active
- 2013-01-07 CA CA2897018A patent/CA2897018C/en active Active
- 2013-01-07 WO PCT/US2013/020602 patent/WO2014107171A1/en active Application Filing
- 2013-01-07 US US14/759,635 patent/US10385116B2/en active Active
- 2013-01-07 AU AU2013204158A patent/AU2013204158B2/en active Active
- 2013-01-07 CN CN202010950265.3A patent/CN112062861A/zh active Pending
- 2013-01-07 JP JP2015551661A patent/JP6322652B2/ja active Active
- 2013-01-07 ES ES13870254T patent/ES2886531T3/es active Active
- 2013-01-07 EP EP21171988.5A patent/EP3922643A1/en not_active Withdrawn
-
2014
- 2014-10-31 US US14/530,569 patent/US20150273024A1/en not_active Abandoned
-
2016
- 2016-05-11 HK HK16105402.3A patent/HK1217499A1/zh unknown
- 2016-12-21 AU AU2016277631A patent/AU2016277631B2/en active Active
-
2019
- 2019-06-18 AU AU2019204253A patent/AU2019204253A1/en not_active Abandoned
- 2019-06-24 US US16/450,913 patent/US10766947B2/en active Active
-
2020
- 2020-07-17 US US16/931,736 patent/US11117952B2/en active Active
-
2021
- 2021-08-09 US US17/397,577 patent/US11987614B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
ES2886531T3 (es) | 2021-12-20 |
CA2897018A1 (en) | 2014-07-10 |
US10385116B2 (en) | 2019-08-20 |
NZ709825A (en) | 2019-08-30 |
BR112015016299A2 (pt) | 2022-01-25 |
CN112062861A (zh) | 2020-12-11 |
AU2013204158B2 (en) | 2016-09-22 |
AU2016277631B2 (en) | 2019-03-21 |
US11117952B2 (en) | 2021-09-14 |
US20210002351A1 (en) | 2021-01-07 |
JP2016508147A (ja) | 2016-03-17 |
EP3922643A1 (en) | 2021-12-15 |
CN105408354B (zh) | 2020-09-18 |
US20150273024A1 (en) | 2015-10-01 |
US11987614B2 (en) | 2024-05-21 |
US10766947B2 (en) | 2020-09-08 |
AU2016277631A1 (en) | 2017-01-19 |
CN105408354A (zh) | 2016-03-16 |
EP2941440A4 (en) | 2016-06-15 |
JP6322652B2 (ja) | 2018-05-09 |
US20220048977A1 (en) | 2022-02-17 |
CA2897018C (en) | 2021-07-27 |
EP2941440B1 (en) | 2021-05-05 |
AU2013204158A1 (en) | 2014-07-24 |
US20200017574A1 (en) | 2020-01-16 |
WO2014107171A1 (en) | 2014-07-10 |
EP2941440A1 (en) | 2015-11-11 |
AU2019204253A1 (en) | 2019-07-04 |
US20160185839A1 (en) | 2016-06-30 |
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