HK1217166A1 - 用於鼓膜癒合的肝素結合表皮生長因數活性的調節 - Google Patents

用於鼓膜癒合的肝素結合表皮生長因數活性的調節

Info

Publication number
HK1217166A1
HK1217166A1 HK16104038.8A HK16104038A HK1217166A1 HK 1217166 A1 HK1217166 A1 HK 1217166A1 HK 16104038 A HK16104038 A HK 16104038A HK 1217166 A1 HK1217166 A1 HK 1217166A1
Authority
HK
Hong Kong
Prior art keywords
heparin
modulation
growth factor
epidermal growth
tympanic membrane
Prior art date
Application number
HK16104038.8A
Other languages
English (en)
Inventor
Maria Peter Luke Santa
Yunzhi Peter Yang
Sungwoo Kim
Chloe Domville-Lewis
Original Assignee
The Board Of Trustees Of The Leland Stanford Junio
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Board Of Trustees Of The Leland Stanford Junio filed Critical The Board Of Trustees Of The Leland Stanford Junio
Publication of HK1217166A1 publication Critical patent/HK1217166A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1808—Epidermal growth factor [EGF] urogastrone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F11/00—Methods or devices for treatment of the ears or hearing sense; Non-electric hearing aids; Methods or devices for enabling ear patients to achieve auditory perception through physiological senses other than hearing sense; Protective devices for the ears, carried on the body or in the hand
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F11/00—Methods or devices for treatment of the ears or hearing sense; Non-electric hearing aids; Methods or devices for enabling ear patients to achieve auditory perception through physiological senses other than hearing sense; Protective devices for the ears, carried on the body or in the hand
    • A61F11/20—Ear surgery
    • A61F11/202—Surgical middle-ear ventilation or drainage, e.g. permanent; Implants therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0046—Ear
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7015—Drug-containing film-forming compositions, e.g. spray-on
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0023—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/0066—Medicaments; Biocides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/0076—Sprayable compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/20—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/18—Internal ear or nose parts, e.g. ear-drums
    • A61F2002/183—Ear parts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
    • A61F2250/0068—Means for introducing or releasing pharmaceutical products into the body the pharmaceutical product being in a reservoir
HK16104038.8A 2013-05-15 2016-04-08 用於鼓膜癒合的肝素結合表皮生長因數活性的調節 HK1217166A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361823749P 2013-05-15 2013-05-15
PCT/US2014/033536 WO2014186075A2 (en) 2013-05-15 2014-04-09 Modulation of heparin-binding epidermal growth factor activity for tympanic membrane healing

Publications (1)

Publication Number Publication Date
HK1217166A1 true HK1217166A1 (zh) 2016-12-30

Family

ID=51898980

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16104038.8A HK1217166A1 (zh) 2013-05-15 2016-04-08 用於鼓膜癒合的肝素結合表皮生長因數活性的調節

Country Status (27)

Country Link
US (3) US20160074476A1 (zh)
EP (2) EP3708181A1 (zh)
JP (1) JP6316943B2 (zh)
KR (1) KR102318748B1 (zh)
CN (2) CN105555296A (zh)
AU (2) AU2014265901B2 (zh)
BR (2) BR112015028367B1 (zh)
CA (1) CA2912411C (zh)
CY (1) CY1123464T1 (zh)
DK (1) DK2996709T3 (zh)
ES (1) ES2805002T3 (zh)
HK (1) HK1217166A1 (zh)
HR (1) HRP20200971T1 (zh)
HU (1) HUE049294T2 (zh)
IL (2) IL242454B (zh)
LT (1) LT2996709T (zh)
MX (2) MX2015015774A (zh)
PH (2) PH12015502577B1 (zh)
PL (1) PL2996709T3 (zh)
PT (1) PT2996709T (zh)
RS (1) RS60412B1 (zh)
RU (2) RU2676483C2 (zh)
SG (1) SG11201509347UA (zh)
SI (1) SI2996709T1 (zh)
UA (1) UA120037C2 (zh)
WO (1) WO2014186075A2 (zh)
ZA (1) ZA201508289B (zh)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102634748B1 (ko) 2018-06-15 2024-02-13 삼성전자주식회사 포토 마스크용 펠리클 및 이의 제조 방법
MX2022001374A (es) 2019-07-31 2022-03-17 Astellas Pharma Inc Composicion farmaceutica para administracion otica.
JPWO2022065404A1 (zh) 2020-09-25 2022-03-31

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AU3124793A (en) 1991-10-29 1993-06-07 Clover Consolidated, Limited Crosslinkable polysaccharides, polycations and lipids useful for encapsulation and drug release
US6514533B1 (en) * 1992-06-11 2003-02-04 Alkermas Controlled Therapeutics, Inc. Device for the sustained release of aggregation-stabilized, biologically active agent
US5827937A (en) 1995-07-17 1998-10-27 Q Med Ab Polysaccharide gel composition
AU725654B2 (en) 1996-05-03 2000-10-19 Innogenetics N.V. New medicaments containing gelatin cross-linked with oxidized polysaccharides
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JP2002512200A (ja) * 1998-04-17 2002-04-23 アンジオジェニックス， インコーポレイテッド 治療的な脈管形成因子およびその使用方法
CA2395902A1 (en) 1999-12-28 2001-07-05 Asger Lau Dalmose Dual chamber syringe with a dual function piston
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US7220431B2 (en) 2002-11-27 2007-05-22 Regents Of The University Of Minnesota Methods and compositions for applying pharmacologic agents to the ear
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JP2016525374A (ja) 2013-04-09 2016-08-25 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー 架橋キトサン−ラクチドヒドロゲル

Also Published As

Publication number Publication date
WO2014186075A2 (en) 2014-11-20
IL242454B (en) 2020-05-31
CA2912411A1 (en) 2014-11-20
PT2996709T (pt) 2020-07-14
EP2996709A4 (en) 2016-11-16
US20160074476A1 (en) 2016-03-17
CA2912411C (en) 2022-10-25
EP3708181A1 (en) 2020-09-16
MX2015015774A (es) 2016-07-26
US11235027B2 (en) 2022-02-01
IL273329A (en) 2020-04-30
DK2996709T3 (da) 2020-06-02
BR122020011229B1 (pt) 2022-06-07
BR112015028367B1 (pt) 2020-12-01
AU2019200630A1 (en) 2019-02-21
PH12015502577A1 (en) 2016-02-29
SG11201509347UA (en) 2015-12-30
JP2016520080A (ja) 2016-07-11
UA120037C2 (uk) 2019-09-25
WO2014186075A3 (en) 2015-06-04
PL2996709T3 (pl) 2021-02-08
RU2676483C2 (ru) 2018-12-29
AU2019200630B2 (en) 2020-08-27
CY1123464T1 (el) 2022-03-24
EP2996709A2 (en) 2016-03-23
JP6316943B2 (ja) 2018-04-25
EP2996709B1 (en) 2020-05-06
BR112015028367A2 (pt) 2017-07-25
KR20160013063A (ko) 2016-02-03
MX2020001319A (es) 2020-03-20
KR102318748B1 (ko) 2021-10-27
CN113559242A (zh) 2021-10-29
PH12020551126A1 (en) 2021-12-13
SI2996709T1 (sl) 2020-09-30
US20180256684A1 (en) 2018-09-13
IL273329B (en) 2021-05-31
LT2996709T (lt) 2020-08-10
RS60412B1 (sr) 2020-07-31
RU2015148636A (ru) 2017-06-20
US11963998B2 (en) 2024-04-23
CN105555296A (zh) 2016-05-04
US20220111006A1 (en) 2022-04-14
HUE049294T2 (hu) 2020-09-28
RU2018146249A (ru) 2019-01-18
HRP20200971T1 (hr) 2020-10-02
ES2805002T3 (es) 2021-02-10
ZA201508289B (en) 2019-02-27
PH12015502577B1 (en) 2016-02-29
AU2014265901B2 (en) 2018-11-08
AU2014265901A1 (en) 2015-11-26

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