HK1214960A1 - Process for purifying heparan-n-sulfatase - Google Patents

Process for purifying heparan-n-sulfatase Download PDF

Info

Publication number
HK1214960A1
HK1214960A1 HK16102969.5A HK16102969A HK1214960A1 HK 1214960 A1 HK1214960 A1 HK 1214960A1 HK 16102969 A HK16102969 A HK 16102969A HK 1214960 A1 HK1214960 A1 HK 1214960A1
Authority
HK
Hong Kong
Prior art keywords
hns
column
nacl
composition
resin
Prior art date
Application number
HK16102969.5A
Other languages
English (en)
Chinese (zh)
Inventor
Nichols David
Original Assignee
Shire Human Genetic Therapies, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shire Human Genetic Therapies, Inc. filed Critical Shire Human Genetic Therapies, Inc.
Publication of HK1214960A1 publication Critical patent/HK1214960A1/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
HK16102969.5A 2011-05-19 2016-03-15 Process for purifying heparan-n-sulfatase HK1214960A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161488090P 2011-05-19 2011-05-19
US201161488090P 2011-05-19

Publications (1)

Publication Number Publication Date
HK1214960A1 true HK1214960A1 (en) 2016-08-12

Family

ID=47177365

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16102969.5A HK1214960A1 (en) 2011-05-19 2016-03-15 Process for purifying heparan-n-sulfatase

Country Status (8)

Country Link
US (1) US20120329133A1 (https=)
EP (2) EP2929892B1 (https=)
JP (2) JP2014517692A (https=)
AR (1) AR086445A1 (https=)
CA (1) CA2836599A1 (https=)
HK (1) HK1214960A1 (https=)
TW (1) TW201307563A (https=)
WO (1) WO2012159053A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11584777B2 (en) 2017-08-31 2023-02-21 Green Cross Corporation Method for purifying a sulfatase protein

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100581574B1 (ko) * 2000-03-22 2006-05-22 옥타게네 게엠베하 인간 세포주 내 재조합 혈액 응고 인자의 제조
CA2478925C (en) * 2002-04-26 2016-06-07 Robert Lee Fahrner Non-affinity purification of proteins
ATE494367T1 (de) * 2002-12-18 2011-01-15 Hoffmann La Roche Rekombinante desoxyribonuclease i aus rinder- pankreas mit hoher spezifischer aktivität
CA2556245A1 (en) * 2004-02-06 2005-08-25 Biomarin Pharmaceutical Inc. Manufacture of highly phosphorylated lysosomal enzymes and uses thereof
DK1828239T3 (da) * 2004-12-10 2011-12-19 Zymogenetics Inc FGF18-produktion i prokaryote værter
WO2008120801A1 (ja) * 2007-04-02 2008-10-09 Kyowa Hakko Kirin Co., Ltd. アンチトロンビン組成物の製造方法
CN105274072A (zh) 2008-01-18 2016-01-27 生物马林药物股份有限公司 制备活性高度磷酸化人溶酶体硫酸酯酶及其应用
NZ605874A (en) * 2010-06-25 2015-02-27 Shire Human Genetic Therapies Methods and compositions for cns delivery of heparan n-sulfatase

Also Published As

Publication number Publication date
AR086445A1 (es) 2013-12-11
JP2014517692A (ja) 2014-07-24
CA2836599A1 (en) 2012-11-22
EP2709654A4 (en) 2014-11-12
EP2929892A1 (en) 2015-10-14
US20120329133A1 (en) 2012-12-27
TW201307563A (zh) 2013-02-16
EP2929892B1 (en) 2018-07-04
EP2709654A1 (en) 2014-03-26
WO2012159053A1 (en) 2012-11-22
JP2017029170A (ja) 2017-02-09

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