HK1214652A1 - 用於检测胰腺癌的方法和组合物 - Google Patents

用於检测胰腺癌的方法和组合物 Download PDF

Info

Publication number
HK1214652A1
HK1214652A1 HK16102515.4A HK16102515A HK1214652A1 HK 1214652 A1 HK1214652 A1 HK 1214652A1 HK 16102515 A HK16102515 A HK 16102515A HK 1214652 A1 HK1214652 A1 HK 1214652A1
Authority
HK
Hong Kong
Prior art keywords
pancreatic cancer
methods
compositions
detecting pancreatic
detecting
Prior art date
Application number
HK16102515.4A
Other languages
English (en)
Chinese (zh)
Inventor
．潘內爾
L．K．潘内尔
．羅克
J.罗克
Original Assignee
克里蒂科斯有限责任公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 克里蒂科斯有限责任公司 filed Critical 克里蒂科斯有限责任公司
Publication of HK1214652A1 publication Critical patent/HK1214652A1/zh

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57438—Specifically defined cancers of liver, pancreas or kidney
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/56—Staging of a disease; Further complications associated with the disease
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK16102515.4A 2013-03-13 2014-03-13 用於检测胰腺癌的方法和组合物 HK1214652A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361780574P 2013-03-13 2013-03-13
US61/780574 2013-03-13
PCT/US2014/026857 WO2014160499A2 (en) 2013-03-13 2014-03-13 Methods and compositions for detecting pancreatic cancer

Publications (1)

Publication Number Publication Date
HK1214652A1 true HK1214652A1 (zh) 2016-07-29

Family

ID=50933479

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16102515.4A HK1214652A1 (zh) 2013-03-13 2014-03-13 用於检测胰腺癌的方法和组合物

Country Status (7)

Country Link
US (3) US20160033511A1 (cg-RX-API-DMAC7.html)
EP (1) EP2972375A2 (cg-RX-API-DMAC7.html)
JP (3) JP6646571B2 (cg-RX-API-DMAC7.html)
AU (3) AU2014243704A1 (cg-RX-API-DMAC7.html)
CA (1) CA2902841A1 (cg-RX-API-DMAC7.html)
HK (1) HK1214652A1 (cg-RX-API-DMAC7.html)
WO (1) WO2014160499A2 (cg-RX-API-DMAC7.html)

Families Citing this family (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2347775T3 (da) 2005-12-13 2020-07-13 Harvard College Skabeloner til celletransplantation
AU2008231575A1 (en) 2007-03-27 2008-10-02 Immunovia Ab Protein signature/markers for the detection of adenocarcinoma
EP2624873B1 (en) 2010-10-06 2019-12-04 President and Fellows of Harvard College Injectable, pore-forming hydrogels for materials-based cell therapies
US9675561B2 (en) 2011-04-28 2017-06-13 President And Fellows Of Harvard College Injectable cryogel vaccine devices and methods of use thereof
HK1200037A1 (en) 2011-09-12 2015-07-31 克里蒂科斯有限责任公司 Non-invasive methods of detecting target molecules
EP2836512B1 (en) 2012-04-11 2018-10-24 F.Hoffmann-La Roche Ag Improved antibody light chains
LT2838515T (lt) 2012-04-16 2020-03-10 President And Fellows Of Harvard College Mezoporinės silico dioksido kompozicijos, skirtos imuninio atsako moduliavimui
EA201492284A1 (ru) 2012-06-27 2015-11-30 Берг Ллк Применение маркеров в диагностике и лечении рака предстательной железы
LT3290046T (lt) 2013-03-15 2019-03-12 Shire Viropharma Incorporated C1-inh kompozicijos ir sutrikimų, susijusių su c1 esterazės inhibitoriaus nepakankamumu, prevencijos bei gydymo būdai
EP3159695A3 (en) * 2013-06-20 2017-07-05 The Trustees of The University of Pennsylvania Methods for diagnosing pancreatic cancer
BR112016023046A8 (pt) 2014-04-04 2021-05-11 Mayo Found Medical Education & Res kit compreendendo anticorpos e agentes redutores
WO2015168379A2 (en) 2014-04-30 2015-11-05 President And Fellows Of Harvard College Combination vaccine devices and methods of killing cancer cells
CN106461678A (zh) * 2014-05-26 2017-02-22 奥林巴斯株式会社 胰腺癌判定方法
KR20160045547A (ko) * 2014-10-17 2016-04-27 에스케이텔레콤 주식회사 췌장암 진단용 조성물 및 이를 이용한 췌장암 진단방법
CN107428821B (zh) 2014-12-08 2022-06-24 博格有限责任公司 包括细丝蛋白a的标志物在诊断和治疗前列腺癌中的用途
US10006915B2 (en) 2014-12-19 2018-06-26 Roche Sequencing Solutions, Inc. System and method for identification and characterization of transglutaminase species
US11054425B2 (en) 2014-12-19 2021-07-06 Roche Sequencing Solutions, Inc. System and method for identification and characterization of transglutaminase species
WO2016096785A1 (en) 2014-12-19 2016-06-23 F. Hoffmann-La Roche Ag Identification of transglutaminase substrates and uses therefor
HK1247861A1 (zh) 2015-01-30 2018-10-05 President And Fellows Of Harvard College 用於癌症治疗的肿瘤周围和肿瘤内部材料
US20160271120A1 (en) * 2015-03-17 2016-09-22 Oakdene Holdings Llc Pharmaceutical composition for cleansing of the gastrointestinal tract
GB201505654D0 (en) * 2015-04-01 2015-05-13 Nordic Bioscience As Immunoassay for collagen type VI sequence
WO2016164593A1 (en) * 2015-04-07 2016-10-13 President And Fellows Of Harvard College Compositions and methods for modulating hydroxylation of acc2 by phd3
CN107708756A (zh) 2015-04-10 2018-02-16 哈佛学院院长等 免疫细胞捕获装置及其制备和使用方法
ES2939013T3 (es) * 2015-04-20 2023-04-18 Consejo Superior Investigacion Agentes que se unen específicamente al motivo RGD de la cadherina 17 humana, la cadherina 5 humana, la cadherina 6 humana y la cadherina 20 humana
HK1254866A1 (zh) 2015-06-25 2019-07-26 Immatics Biotechnologies Gmbh 用於骨髓瘤和其他癌症免疫治疗的新型细胞表位和细胞表位组合物
GB201511191D0 (en) * 2015-06-25 2015-08-12 Immatics Biotechnologies Gmbh T-cell epitopes for the immunotherapy of myeloma
WO2017036369A1 (en) * 2015-09-03 2017-03-09 The University Of Hong Kong A monoclonal antibody for predicting tamoxifen response in breast cancer patients
WO2017053932A1 (en) 2015-09-24 2017-03-30 Mayo Foundation For Medical Education And Research Identification of immunoglobulin free light chains by mass spectrometry
CN105296613A (zh) * 2015-09-24 2016-02-03 郑州市职业病防治院 一种人TERF1基因rs3863242位点多态性检测技术
WO2017095632A1 (en) * 2015-11-30 2017-06-08 Mayo Foundation For Medical Education And Research Heatr1 as a marker for chemoresistance
CN105785013A (zh) * 2016-04-21 2016-07-20 卢连伟 一种辅助检测胰腺癌的胶体金免疫层析试纸及其制备方法
GB201608192D0 (en) * 2016-05-10 2016-06-22 Immunovia Ab Method, array and use thereof
JP7075125B2 (ja) * 2016-05-25 2022-05-25 イマティクス バイオテクノロジーズ ゲーエムベーハー 標的としてのおよび胆嚢がんおよび胆管がんおよびその他のがんに対する免疫療法で使用するための新規ペプチド、ペプチド組み合わせ
ES3032115T3 (en) 2016-07-13 2025-07-15 Harvard College Antigen-presenting cell-mimetic scaffolds and methods for making and using the same
WO2018026884A1 (en) 2016-08-02 2018-02-08 President And Fellows Of Harvard College Biomaterials for modulating immune responses
EP3523647B1 (en) 2016-09-07 2024-06-26 Mayo Foundation for Medical Education and Research Identification and monitoring of cleaved immunoglobulins by molecular mass
CN107655985B (zh) * 2017-08-25 2020-05-26 南京农业大学 一种基于lc-ms-ms技术的体内蛋白质营养的评价方法
EP3681907A4 (en) 2017-09-13 2021-07-07 Mayo Foundation for Medical Education and Research IDENTIFICATION AND MONITORING OF IMMUNOGLOBULIN J-CHAINS
WO2019055634A1 (en) 2017-09-13 2019-03-21 Mayo Foundation For Medical Education And Research IDENTIFICATION AND MONITORING OF A MACROPHAGE APOPTOSIS INHIBITOR
CA3092292A1 (en) * 2018-04-03 2019-10-10 Creatics Llc Methods for cancer detection by evaluation of glycan-binding patterns of immunoglobulins in gastrointestinal lavage fluid samples
WO2020061129A1 (en) 2018-09-19 2020-03-26 President And Fellows Of Harvard College Compositions and methods for labeling and modulation of cells in vitro and in vivo
WO2020101878A2 (en) * 2018-10-29 2020-05-22 The Johns Hopkins University Rasopathy treatment
WO2020223646A1 (en) * 2019-05-02 2020-11-05 Creatics Llc Methods for cancer detection by evaluation of alpha-1-antitrypsin (aat) and chymotrypsin-like elastase in gastrointestinal lavage fluid samples
BR112021026192A2 (pt) * 2019-06-24 2022-06-07 Urteste S A Marcador de diagnóstico para câncer pancreático
EP4045912A1 (en) * 2019-10-18 2022-08-24 Reccan Diagnostics AB Apparatuses and methods for detection of pancreatic cancer
WO2021239692A1 (en) * 2020-05-26 2021-12-02 F. Hoffmann-La Roche Ag Computer implemented method for calibrating a customer mass spectrometry instrument for quantifier-qualifier-ratio check
GB202010970D0 (en) 2020-07-16 2020-09-02 Immunovia Ab Methods, arrays and uses thereof
KR102448586B1 (ko) * 2020-10-08 2022-09-27 가톨릭대학교 산학협력단 췌장암 환자의 항암제 치료 반응성 예측용 마커
JP2024501581A (ja) * 2020-12-08 2024-01-12 メモリアル スローン－ケタリング キャンサー センター ガレクチン－３に対する抗体及びその使用方法
CN112461915B (zh) * 2020-12-08 2024-07-12 杭州汇健科技有限公司 一种与药物敏感相关的特征分子筛选、药敏程度检测、细胞亚型检测的方法
WO2022140116A1 (en) 2020-12-21 2022-06-30 Freenome Holdings, Inc. Markers for the early detection of colon cell proliferative disorders
WO2022171777A1 (en) * 2021-02-12 2022-08-18 INSERM (Institut National de la Santé et de la Recherche Médicale) Method for prognosis and treating a patient suffering from cancer
US12179064B2 (en) * 2021-04-11 2024-12-31 Vikas Khurana System, apparatus and method for training a subject
JP2024522607A (ja) * 2021-06-07 2024-06-21 フラッグシップ パイオニアリング イノベーションズ セブン，エルエルシー 治療薬の標的化送達のための組成物及び方法
CA3232274A1 (en) * 2021-09-20 2023-03-23 Jose P. Zevallos Drain fluid for diagnostics
US12152280B2 (en) 2021-09-20 2024-11-26 Droplet Biosciences, Inc. Drain fluid for diagnostics
US12416626B2 (en) 2022-07-22 2025-09-16 Droplet Biosciences, Inc. Methods for evaluating candidate therapy efficacy based on changes in lymphatic fluid biomarkers
WO2024086298A2 (en) * 2022-10-20 2024-04-25 The Johns Hopkins University Hla class i and class ii-restricted t-cell epitopes in pancreatic cancer tissues and uses thereof
WO2024206856A2 (en) * 2023-03-30 2024-10-03 Thomas Jefferson University Dna-dependent synthesis of rna by dna polymerase theta variants

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE28937T1 (de) * 1982-08-09 1987-08-15 Centocor Inc Immunotest fuer kohlehydrat-antigen-determinant.
JPH0673470B2 (ja) * 1986-07-15 1994-09-21 協和醗酵工業株式会社 抗ヒト胃癌単クロ−ン性抗体ａｍｃ−４６２
US5359681A (en) 1993-01-11 1994-10-25 University Of Washington Fiber optic sensor and methods and apparatus relating thereto
US6924153B1 (en) 1997-03-06 2005-08-02 Quidel Corporation Quantitative lateral flow assays and devices
JPH11225800A (ja) * 1998-02-10 1999-08-24 Kureha Chem Ind Co Ltd 体液を用いた癌検出方法及びキット
US6447763B1 (en) * 1998-06-12 2002-09-10 Ian L. Gordon Method and system for production and collection of lavage induced stool (LIS) for chemical and biologic tests of cells
EP1298205A4 (en) * 2000-07-03 2004-06-16 Mochida Pharm Co Ltd NEW LIPASE
AU2002322864A1 (en) * 2001-08-03 2003-02-24 Origene Technologies, Inc. Full-length prostate selective polynucleotides and polypeptides
US7291324B2 (en) * 2002-10-22 2007-11-06 Braintree Laboratories Inc. Method of bowel cleansing
AU2003294828A1 (en) * 2002-12-17 2004-07-09 Sinogenomax Co. Ltd. Chinese National Human Genomecenter Specific markers for pancreatic cancer
JP4733644B2 (ja) * 2003-11-26 2011-07-27 ダナ−ファーバー キャンサー インスティテュート インク． 膵臓腺癌の動物モデルおよびその使用
DK1766412T3 (da) 2004-05-21 2009-05-25 Inst Systems Biology Sammensætninger og fremgangsmåder til kvantificering af serumglycoproteiner
JP2009528507A (ja) 2006-03-02 2009-08-06 オンコセラピー・サイエンス株式会社 Ｒｅｇ４タンパク質を用いて膵癌を診断する方法
WO2009102788A2 (en) * 2008-02-15 2009-08-20 Mayo Foundation For Medical Education And Research Detecting neoplasm
US20090258090A1 (en) 2008-04-11 2009-10-15 Braintree Laboratories, Inc. Colon cleansing solution
CN102414565B (zh) * 2009-05-04 2014-09-24 霍夫曼-拉罗奇有限公司 作为癌症的标记物的DPPIV/Seprase的用途
WO2011027311A2 (en) * 2009-09-03 2011-03-10 Koninklijke Philips Electronics N.V. Novel tumor markers
CA2779730C (en) * 2009-11-05 2019-04-30 University Of Virginia Patent Foundation Compositions and methods for detecting plectin-1 as a biomarker for cancer
WO2011151252A2 (en) * 2010-06-01 2011-12-08 Metanomics Health Gmbh Means and methods for diagnosing pancreatic cancer in a subject
KR101857462B1 (ko) * 2010-08-13 2018-05-14 소마로직, 인크. 췌장암 바이오마커 및 그것의 용도
AU2011351990A1 (en) * 2010-12-29 2013-07-18 Expression Pathology, Inc. Protein biomarkers of recurrent breast cancer
EP2696202B1 (en) * 2011-04-05 2017-09-06 Olympus Corporation Pancreas test method, and pancreas test kit
HK1200037A1 (en) * 2011-09-12 2015-07-31 克里蒂科斯有限责任公司 Non-invasive methods of detecting target molecules

Also Published As

Publication number Publication date
JP2022141755A (ja) 2022-09-29
JP6646571B2 (ja) 2020-02-14
AU2014243704A1 (en) 2015-09-10
AU2020202066B2 (en) 2022-06-02
JP2020091295A (ja) 2020-06-11
AU2022224782A1 (en) 2022-09-22
WO2014160499A2 (en) 2014-10-02
US20160033511A1 (en) 2016-02-04
CA2902841A1 (en) 2014-10-02
WO2014160499A3 (en) 2015-01-29
JP7109008B2 (ja) 2022-08-10
AU2020202066A1 (en) 2020-04-09
JP2016519285A (ja) 2016-06-30
US20220128563A1 (en) 2022-04-28
US20190234951A1 (en) 2019-08-01
EP2972375A2 (en) 2016-01-20

Similar Documents

Publication Publication Date Title
HK1214652A1 (zh) 用於检测胰腺癌的方法和组合物
WO2014031859A3 (en) Compositions and methods relating to blood-based biomarkers of breast cancer
HK1199100A1 (en) Methods and compositions for the treatment and diagnosis of colorectal cancer
WO2014124334A3 (en) Transthyretin antibodies and uses thereof
WO2012006476A3 (en) Methods and compositions for quantifying exosomes
WO2012009567A3 (en) Biomarkers for diagnosis of stroke and its causes
HK1199290A1 (en) Methods and compositions for the treatment and diagnosis of breast cancer
WO2015061634A3 (en) Biomarkers and diagnostic methods for alzheimer's disease and other neurodegenerative disorders
HK1202313A1 (en) Methods and compositions for the treatment and diagnosis of bladder cancer
MX340453B (es) Biomarcadores para cancer de pulmon.
WO2013107459A3 (en) Microrna for diagnosis of pancreatic cancer and/or prognosis of patients with pancreatic cancer by blood samples
EP3077979A4 (en) Determining merchant identity for received merchant identifiers
WO2012083969A3 (en) Microrna for diagnosis of pancreatic cancer
EP3176268A4 (en) Novel biomarker for predicting sensitivity to egfr-targeting agent, and use thereof
EP2996721A4 (en) Methods and compositions for prognosis, diagnosis and treatment of adam8-expressing cancer
WO2014036040A3 (en) Methods for diagnosis, prognosis and methods of treatment
WO2014197835A3 (en) Methods and compositions for the treatment of cancer
WO2013106747A3 (en) Methods and compositions for the treatment and diagnosis of thyroid cancer
HK1220253A1 (zh) 诊断前列腺癌症的方法
EP3054298A4 (en) Method for detecting pancreatic tumor, antibody, and pancreatic tumor detection kit
MX2016006165A (es) Composiciones y metodos para valorar la funcion intestinal.
WO2012154908A3 (en) Hairy cell leukemia biomarkers and methods of using same
WO2013124738A3 (en) Methods and biomarkers for detection and prognosis of cervical cancer
WO2013082249A3 (en) Compositions and methods for prostate cancer analysis
IL239704B (en) New antibody fragments, their composition and use