HK1213325A1 - 用於體內原位和/或實時靶定分析物的生物感應器裝置及其製造與使用方法 - Google Patents

用於體內原位和/或實時靶定分析物的生物感應器裝置及其製造與使用方法

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Publication number
HK1213325A1
HK1213325A1 HK16101319.4A HK16101319A HK1213325A1 HK 1213325 A1 HK1213325 A1 HK 1213325A1 HK 16101319 A HK16101319 A HK 16101319A HK 1213325 A1 HK1213325 A1 HK 1213325A1
Authority
HK
Hong Kong
Prior art keywords
situ
vivo
making
methods
real time
Prior art date
Application number
HK16101319.4A
Other languages
English (en)
Inventor
．阿加瓦爾
．戈爾
．吉姆
．尹
．林
．費茲扎納
Original Assignee
Univ Toledo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Toledo filed Critical Univ Toledo
Publication of HK1213325A1 publication Critical patent/HK1213325A1/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
    • A61B5/1473—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
    • A61B5/14735—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter comprising an immobilised reagent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438—Electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/45—For evaluating or diagnosing the musculoskeletal system or teeth
    • A61B5/4538—Evaluating a particular part of the muscoloskeletal system or a particular medical condition
    • A61B5/4542—Evaluating the mouth, e.g. the jaw
    • A61B5/4547—Evaluating teeth
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G01N27/3272—Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3275—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
    • G01N27/3276—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction being a hybridisation with immobilised receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/56938—Staphylococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2503/00—Evaluating a particular growth phase or type of persons or animals
    • A61B2503/40—Animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/12—Manufacturing methods specially adapted for producing sensors for in-vivo measurements
    • A61B2562/125—Manufacturing methods specially adapted for producing sensors for in-vivo measurements characterised by the manufacture of electrodes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Optics & Photonics (AREA)
  • Electrochemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Dentistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
HK16101319.4A 2013-03-11 2016-02-04 用於體內原位和/或實時靶定分析物的生物感應器裝置及其製造與使用方法 HK1213325A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361775939P 2013-03-11 2013-03-11
PCT/US2014/023126 WO2014164654A1 (en) 2013-03-11 2014-03-11 A biosensor device to target analytes in situ, in vivo, and/or in real time, and methods of making and using the same

Publications (1)

Publication Number Publication Date
HK1213325A1 true HK1213325A1 (zh) 2016-06-30

Family

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HK16101319.4A HK1213325A1 (zh) 2013-03-11 2016-02-04 用於體內原位和/或實時靶定分析物的生物感應器裝置及其製造與使用方法

Country Status (5)

Country Link
US (1) US10849540B2 (zh)
EP (1) EP2972333B1 (zh)
CN (1) CN105190310B (zh)
HK (1) HK1213325A1 (zh)
WO (1) WO2014164654A1 (zh)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9675427B2 (en) 2013-06-07 2017-06-13 Align Technology, Inc. Adjusting a tooth position
EP3149465B1 (en) * 2014-05-27 2020-01-29 Case Western Reserve University Electrochemical sensor for analyte detection
US10449016B2 (en) 2014-09-19 2019-10-22 Align Technology, Inc. Arch adjustment appliance
US9610141B2 (en) 2014-09-19 2017-04-04 Align Technology, Inc. Arch expanding appliance
US10504386B2 (en) 2015-01-27 2019-12-10 Align Technology, Inc. Training method and system for oral-cavity-imaging-and-modeling equipment
CN104849322B (zh) * 2015-04-22 2017-10-24 中国农业大学 一种阻抗生物传感器及生物阻抗检测分析方法
US20170059561A1 (en) * 2015-08-28 2017-03-02 The Florida International University Board Of Trustees Thermally Stable Electrochemical Sensor With Long Shelf-Life
US20180271423A1 (en) * 2015-10-07 2018-09-27 The University Of Toledo A biosensor device to detect target analytes in situ, in vivo, and/or in real time, and methods of making and using the same
US11554000B2 (en) 2015-11-12 2023-01-17 Align Technology, Inc. Dental attachment formation structure
CN105372423B (zh) * 2015-11-22 2018-03-20 长沙市食品质量安全监督检测中心 基于微间距阵列电极的免疫定量传感器检测金黄色葡萄球菌的试剂盒及方法
US11103330B2 (en) 2015-12-09 2021-08-31 Align Technology, Inc. Dental attachment placement structure
US11596502B2 (en) 2015-12-09 2023-03-07 Align Technology, Inc. Dental attachment placement structure
US10470847B2 (en) 2016-06-17 2019-11-12 Align Technology, Inc. Intraoral appliances with sensing
EP3471653B1 (en) 2016-06-17 2021-12-22 Align Technology, Inc. Orthodontic appliance performance monitor
CN208942463U (zh) 2016-07-27 2019-06-07 阿莱恩技术有限公司 口内扫描系统和口内扫描装置
US10768139B2 (en) * 2016-09-08 2020-09-08 The Francis Crick Institute Limited Electrochemical probe
CN106770588B (zh) * 2016-11-25 2019-04-16 深圳大学 一种肌氨酸检测装置及其制备方法、应用
CN106770566B (zh) * 2016-11-25 2019-04-16 深圳大学 沙门氏菌传感器、制备方法及沙门氏菌浓度的检测方法
WO2018102809A1 (en) 2016-12-02 2018-06-07 Align Technology, Inc. Palatal expanders and methods of expanding a palate
US11376101B2 (en) 2016-12-02 2022-07-05 Align Technology, Inc. Force control, stop mechanism, regulating structure of removable arch adjustment appliance
US11686722B2 (en) 2016-12-16 2023-06-27 Infusense Corp. Compositions and methods to detect molecules in a sample
US10548700B2 (en) 2016-12-16 2020-02-04 Align Technology, Inc. Dental appliance etch template
US10779718B2 (en) 2017-02-13 2020-09-22 Align Technology, Inc. Cheek retractor and mobile device holder
WO2018176042A1 (en) * 2017-03-24 2018-09-27 Iowa State University Research Foundation, Inc. Electrochemical immunosensors
US20180317774A1 (en) * 2017-05-02 2018-11-08 Covidien Lp Infection detection devices and methods
US10900924B2 (en) 2017-06-19 2021-01-26 International Business Machines Corporation Porous nanostructured electrodes for detection of neurotransmitters
WO2019005808A1 (en) * 2017-06-26 2019-01-03 Align Technology, Inc. BIOCAPTOR PERFORMANCE INDICATOR FOR INTRABUCCAL DEVICES
CN107349205A (zh) * 2017-07-11 2017-11-17 东新皓特（北京）生化科技有限公司 河豚毒素在制备治疗犬瘟热的药物组合物中应用、药物组合物、制备方法及药物制剂
CN115462921A (zh) 2017-07-27 2022-12-13 阿莱恩技术有限公司 牙齿着色、透明度和上釉
CN109387553A (zh) * 2017-08-02 2019-02-26 张迎阳 一种基于CdSe量子点的赭曲霉素A免疫传感器的制备及其检测方法
US11116605B2 (en) 2017-08-15 2021-09-14 Align Technology, Inc. Buccal corridor assessment and computation
US11123156B2 (en) 2017-08-17 2021-09-21 Align Technology, Inc. Dental appliance compliance monitoring
BR112020003691A2 (pt) * 2017-08-25 2020-09-01 Graftech International Holdings Inc. sistemas e métodos para identificação e monitoramento de eletrodo de grafite
US11576752B2 (en) 2017-10-31 2023-02-14 Align Technology, Inc. Dental appliance having selective occlusal loading and controlled intercuspation
CN111315315B (zh) 2017-11-01 2022-08-23 阿莱恩技术有限公司 自动治疗规划
WO2019100022A1 (en) 2017-11-17 2019-05-23 Align Technology, Inc. Orthodontic retainers
CN111417357B (zh) 2017-11-30 2022-07-26 阿莱恩技术有限公司 用于监测口腔矫治器的传感器
WO2019118876A1 (en) 2017-12-15 2019-06-20 Align Technology, Inc. Closed loop adaptive orthodontic treatment methods and apparatuses
US10980613B2 (en) 2017-12-29 2021-04-20 Align Technology, Inc. Augmented reality enhancements for dental practitioners
KR20200115580A (ko) 2018-01-26 2020-10-07 얼라인 테크널러지, 인크. 구강 내 진단 스캔 및 추적
US11937991B2 (en) 2018-03-27 2024-03-26 Align Technology, Inc. Dental attachment placement structure
AU2019251474A1 (en) 2018-04-11 2020-10-29 Align Technology, Inc. Releasable palatal expanders
CN108693229B (zh) * 2018-05-22 2019-11-15 上海市农业科学院 一种用于检测展青霉素的分子印迹电化学传感器及制备方法
CN108576577B (zh) * 2018-06-13 2021-06-25 上海海洋大学 快速降解河豚毒素的方法及药剂
CN112294319A (zh) * 2019-08-02 2021-02-02 华广生技股份有限公司 植入式微型生物传感器的制造方法
CN110423714B (zh) * 2019-08-19 2020-11-06 中国水产科学研究院长江水产研究所 一种乳酸菌复合菌剂及其在抗鲤疱疹病毒ii型中的应用
CN111175364B (zh) * 2020-01-15 2022-02-15 江苏大学 一种同时检测黄曲霉毒素b1和赭曲霉毒素a的比率电化学适配体传感器的制备方法
CN113215292A (zh) * 2021-06-05 2021-08-06 山东新希望六和农牧科技有限公司 检测猪增生性肠病病原菌胞内劳森菌的TaqMan-LNA试剂盒及方法
CN115078495A (zh) * 2022-04-27 2022-09-20 南京理工大学 一种结合夹心式生物传感器的便携式幽门螺杆菌检测仪

Family Cites Families (112)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4209585A (en) 1978-07-14 1980-06-24 Branscombe Richard A Method and apparatus for the automatic microbiological sampling of a liquid product
US4267270A (en) 1979-05-21 1981-05-12 Enzyme Technology, Inc. Method for the determination of antigens and antibodies using site-deactivating media
US4765341A (en) * 1981-06-22 1988-08-23 Mieczyslaw Mirowski Cardiac electrode with attachment fin
GB8314523D0 (en) 1983-05-25 1983-06-29 Lowe C R Diagnostic device
US6846654B1 (en) 1983-11-29 2005-01-25 Igen International, Inc. Catalytic antibodies as chemical sensors
US4704353A (en) 1984-04-27 1987-11-03 Molecular Devices Corporation Photoresponsive redox detection and discrimination
US4883057A (en) 1984-05-09 1989-11-28 Research Foundation, The City University Of New York Cathodic electrochemical current arrangement with telemetric application
US5140393A (en) 1985-10-08 1992-08-18 Sharp Kabushiki Kaisha Sensor device
US4822566A (en) 1985-11-19 1989-04-18 The Johns Hopkins University Optimized capacitive sensor for chemical analysis and measurement
US5482830A (en) 1986-02-25 1996-01-09 Biostar, Inc. Devices and methods for detection of an analyte based upon light interference
US4847193A (en) 1987-06-18 1989-07-11 Gene-Trak Systems Signal amplification in an assay employing a piezoelectric oscillator
US5203327A (en) 1988-09-08 1993-04-20 Sudor Partners Method and apparatus for determination of chemical species in body fluid
SE8804074D0 (sv) 1988-11-10 1988-11-10 Pharmacia Ab Sensorenhet och dess anvaendning i biosensorsystem
US5063081A (en) 1988-11-14 1991-11-05 I-Stat Corporation Method of manufacturing a plurality of uniform microfabricated sensing devices having an immobilized ligand receptor
US4927502A (en) 1989-01-31 1990-05-22 Board Of Regents, The University Of Texas Methods and apparatus using galvanic immunoelectrodes
US5541057A (en) 1989-09-18 1996-07-30 Biostar, Inc. Methods for detection of an analyte
GB9217808D0 (en) 1992-08-21 1992-10-07 Unilever Plc Advisory method
GB9320850D0 (en) 1993-10-09 1993-12-01 Terwee Thomas H M Monitoring the concentration of a substance or a group of substances in a body fluid of a human or an animal
US5458140A (en) 1993-11-15 1995-10-17 Non-Invasive Monitoring Company (Nimco) Enhancement of transdermal monitoring applications with ultrasound and chemical enhancers
US5494562A (en) 1994-06-27 1996-02-27 Ciba Corning Diagnostics Corp. Electrochemical sensors
DE4430023A1 (de) 1994-08-24 1996-02-29 Boehringer Mannheim Gmbh Elektrochemischer Sensor
US5629213A (en) 1995-03-03 1997-05-13 Kornguth; Steven E. Analytical biosensor
US6346387B1 (en) 1995-06-27 2002-02-12 Xanthon, Inc. Detection of binding reactions using labels detected by mediated catalytic electrochemistry
WO1997005477A1 (en) 1995-08-01 1997-02-13 Australian Membrane And Biotechnology Research Institute Composite membrane sensor
US5628890A (en) * 1995-09-27 1997-05-13 Medisense, Inc. Electrochemical sensor
US6541213B1 (en) 1996-03-29 2003-04-01 University Of Washington Microscale diffusion immunoassay
US6107080A (en) 1996-04-25 2000-08-22 Mcgill University Biosensor device and method
SE9703314D0 (sv) 1997-09-15 1997-09-15 Sangtec Medical Ab Capacity affinity sensor
US6267722B1 (en) 1998-02-03 2001-07-31 Adeza Biomedical Corporation Point of care diagnostic systems
US6346376B1 (en) 1998-06-03 2002-02-12 Centre Suisse D'electronique Et De Mictotechnique Sa Optical sensor unit and procedure for the ultrasensitive detection of chemical or biochemical analytes
IL124903A0 (en) 1998-06-15 1999-01-26 Bauer Alan Josef An enzyme biosensor
US6322963B1 (en) 1998-06-15 2001-11-27 Biosensor Systems Design., Inc. Sensor for analyte detection
USRE38525E1 (en) 1998-07-03 2004-06-08 Torsana Diabetes Diagnostics A/S Optical sensor for in situ measurement of analytes
US6573107B1 (en) 1998-08-05 2003-06-03 The University Of Wyoming Immunochemical detection of an explosive substance in the gas phase through surface plasmon resonance spectroscopy
RU2161653C2 (ru) 1998-08-24 2001-01-10 ФАРМАКОВСКИЙ Дмитрий Александрович Способ количественного электрохимического анализа биомолекул
EP1132397A4 (en) 1998-11-11 2002-10-23 Mitsubishi Chem Corp 'SENSOR PROTEIN' AND ITS USE
US6833267B1 (en) * 1998-12-30 2004-12-21 Clinical Micro Sensors, Inc. Tissue collection devices containing biosensors
US6787368B1 (en) 1999-03-02 2004-09-07 Helix Biopharma Corporation Biosensor method for detecting analytes in a liquid
US6942771B1 (en) * 1999-04-21 2005-09-13 Clinical Micro Sensors, Inc. Microfluidic systems in the electrochemical detection of target analytes
US6503701B1 (en) 1999-06-15 2003-01-07 Biosensor Systems Design, Inc. Analytic sensor apparatus and method
ATE499988T1 (de) 2000-03-02 2011-03-15 Microchips Inc Mikromechanische geräte und verfahren zur speicherung und zur selektiven exposition von chemikalien
US6375829B1 (en) 2000-03-07 2002-04-23 Nalco Chemical Company Method and apparatus for measuring scaling capacity of calcium oxalate solutions using an electrochemically controlled pH change in the solution proximate to a piezoelectric microbalance
WO2001083674A1 (en) 2000-05-03 2001-11-08 Gau Jen Jr Biological identification system with integrated sensor chip
WO2001082784A2 (en) 2000-05-03 2001-11-08 Cornell Research Foundation, Inc. Enhanced biologically based chronotropic biosensing
US6602400B1 (en) 2000-06-15 2003-08-05 Motorola, Inc. Method for enhanced bio-conjugation events
US7125660B2 (en) 2000-09-13 2006-10-24 Archemix Corp. Nucleic acid sensor molecules and methods of using same
US6967074B2 (en) 2000-11-08 2005-11-22 Surface Logix, Inc. Methods of detecting immobilized biomolecules
US7422860B2 (en) 2001-02-07 2008-09-09 Massachusetts Institute Of Technology Optoelectronic detection system
US8216797B2 (en) 2001-02-07 2012-07-10 Massachusetts Institute Of Technology Pathogen detection biosensor
US7521019B2 (en) 2001-04-11 2009-04-21 Lifescan, Inc. Sensor device and methods for manufacture
US7052854B2 (en) 2001-05-23 2006-05-30 University Of Florida Research Foundation, Inc. Application of nanotechnology and sensor technologies for ex-vivo diagnostics
EP1390733B1 (en) 2001-05-30 2010-05-19 i-SENS, INC. Biosensor
US6795722B2 (en) * 2001-06-18 2004-09-21 Neotech Products, Inc. Electrode sensor package and application to the skin of a newborn or infant
US6544729B2 (en) 2001-07-20 2003-04-08 University Of Tennessee Bioluminescent biosensor device
US6751491B2 (en) 2001-09-01 2004-06-15 M Biotech Inc Analyte measuring biosensor chip using image scanning system
US6821529B2 (en) 2001-09-05 2004-11-23 Deanna Jean Nelson Oligo(ethylene glycoll)-terminated 1,2-dithiolanes and their conjugates useful for preparing self-assembled monolayers
WO2003036225A1 (en) 2001-10-26 2003-05-01 University Of Rochester Method for biomolecular sensing and system thereof
AUPS159702A0 (en) 2002-04-09 2002-05-16 Tong, Sun Wing Molecular detection and assay by magneto-thermal biochip micro-assay
US7687258B1 (en) 2002-05-20 2010-03-30 Maki Wusi C Direct electric biological agent detector
AU2003240561A1 (en) 2002-06-06 2003-12-22 Rutgers, The State University Of New Jersey MULTIFUNCTIONAL BIOSENSOR BASED ON ZnO NANOSTRUCTURES
US7309614B1 (en) 2002-12-04 2007-12-18 Sru Biosystems, Inc. Self-referencing biodetection method and patterned bioassays
EP1578260B1 (en) * 2002-12-16 2012-10-24 Given Imaging Ltd. Device, system and method for selective activation of in vivo sensors
WO2005016115A2 (en) 2003-01-23 2005-02-24 Montana State University Biosensors utilizing dendrimer-immobilized ligands and their use thereof
US7309566B2 (en) 2003-03-25 2007-12-18 Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of National Defense Genetically biotinylated recombinant antibody in immunofiltration assay by light addressable potentiometric sensor for identification of Venezuelan equine encephalitis virus
WO2004106891A2 (en) 2003-05-22 2004-12-09 University Of Hawaii Ultrasensitive biochemical sensor
KR100547015B1 (ko) 2003-05-23 2006-01-26 주식회사 올메디쿠스 일정한 크기 이상의 분석물질을 정량 분석하기 위한바이오센서 및 그 제조방법
US8886273B2 (en) 2003-08-01 2014-11-11 Dexcom, Inc. Analyte sensor
US8346482B2 (en) 2003-08-22 2013-01-01 Fernandez Dennis S Integrated biosensor and simulation system for diagnosis and therapy
US7317216B2 (en) 2003-10-31 2008-01-08 University Of Hawaii Ultrasensitive biochemical sensing platform
JP4526839B2 (ja) 2004-03-05 2010-08-18 株式会社資生堂 角層中の酸化タンパク質を指標とする角層の透明性・保水性を評価する方法
US7531002B2 (en) 2004-04-16 2009-05-12 Depuy Spine, Inc. Intervertebral disc with monitoring and adjusting capabilities
CA2566962A1 (en) 2004-05-21 2005-12-01 Atonomics A/S Surface acoustic wave sensor comprising a hydrogel
US20080204043A1 (en) * 2004-10-27 2008-08-28 University Of Florida Research Foundation, Inc. Real-Time Assessment of Biomarkers for Disease
US7349080B2 (en) 2004-12-30 2008-03-25 Corning Incorporated Label-independent detection of unpurified analytes
US8095198B2 (en) * 2006-01-31 2012-01-10 Warsaw Orthopedic. Inc. Methods for detecting osteolytic conditions in the body
EP2016408A2 (en) 2006-05-03 2009-01-21 Koninklijke Philips Electronics N.V. Biosensor device
US8349604B2 (en) 2006-06-15 2013-01-08 University Of South Florida Nano-based device for detection of disease biomarkers and other target molecules
JP4695025B2 (ja) 2006-06-19 2011-06-08 株式会社日立製作所 生体及び化学反応分析キット
KR100777973B1 (ko) * 2006-07-13 2007-11-29 한국표준과학연구원 다중선형전극 센서 유닛으로 이루어진 바이오센서
JP2010503856A (ja) * 2006-09-14 2010-02-04 エージェンシー フォー サイエンス， テクノロジー アンド リサーチ 櫛型微小電極と導電性ポリマーとを有する電気化学的センサ
US8153445B2 (en) 2006-09-19 2012-04-10 Cmed Technologies Ltd. Method for screening of infectious agents in blood
US8158342B2 (en) 2006-09-25 2012-04-17 Cmed Technologies Ltd. Method for the identification of human immunodeficiency virus related antibodies in blood
ATE519423T1 (de) 2006-09-27 2011-08-15 Univ Connecticut Implantierbarer biosensor und anwendungsverfahren
US7863035B2 (en) * 2007-02-15 2011-01-04 Osmetech Technology Inc. Fluidics devices
US7766862B2 (en) 2007-04-19 2010-08-03 Medtronic, Inc. Baseline acquisition for infection monitoring
US8017408B2 (en) 2007-04-27 2011-09-13 The Regents Of The University Of California Device and methods of detection of airborne agents
US8623196B2 (en) 2007-05-16 2014-01-07 Michigan State University Nanostructured biosensor containing neuropathy target esterase activity
WO2008154416A2 (en) 2007-06-07 2008-12-18 Microchips, Inc. Electrochemical biosensors and arrays
EP2008584A1 (en) 2007-06-26 2008-12-31 Julius-Maximilians-Universität Würzburg In vivo device, system and usage thereof
US8465981B2 (en) * 2007-08-06 2013-06-18 University Of Kentucky Research Foundation Polypeptides, systems, and methods useful for detecting glucose
US9439585B2 (en) 2008-02-04 2016-09-13 Ascensia Diabetes Care Holdings Ag Semiconductor based analyte sensors and methods
US8450056B2 (en) 2008-05-02 2013-05-28 University Of Rochester Arrayed imaging reflectometry (AIR) sensor chip comprising virus-like particles suitable for the detection of antiviral immune responses
CN102084252B (zh) 2008-05-02 2017-03-22 罗切斯特大学 用于流感免疫应答测量的阵列检测器系统
US8679772B2 (en) * 2008-06-06 2014-03-25 Agency For Science, Technology And Research Immunoassay
US9474831B2 (en) * 2008-12-04 2016-10-25 Gearbox, Llc Systems, devices, and methods including implantable devices with anti-microbial properties
US20120209090A1 (en) * 2011-02-14 2012-08-16 Searete Llc, A Limited Liability Corporation Of The Sate Of Delaware Systems, devices, and methods including implantable devices with anti-microbial properties
US8106428B2 (en) 2009-03-03 2012-01-31 Board Of Regents, The University Of Texas System Nano-scale bridge biosensors
EP2264460A1 (en) * 2009-06-18 2010-12-22 Nxp B.V. Device having self-assembled-monolayer
US20100326842A1 (en) * 2009-06-30 2010-12-30 Abbott Diabetes Care Inc. Extruded Electrode Structures and Methods of Using Same
CN102471796A (zh) * 2009-07-27 2012-05-23 舒尔传感器有限公司 传感器设备的改进
US8898069B2 (en) 2009-08-28 2014-11-25 The Invention Science Fund I, Llc Devices and methods for detecting an analyte in salivary fluid
US8653833B2 (en) * 2009-11-19 2014-02-18 The Royal Institution For The Advancement Of Learning / Mcgill University Self calibrating high throughput integrated impedance spectrometer for biological applications
US8591459B2 (en) 2009-12-21 2013-11-26 Ethicon Endo-Surgery, Inc. Use of biomarkers and therapeutic agents with surgical devices
CN102939543B (zh) * 2010-02-12 2015-06-24 西北大学 用于样本采集、处理和反应的测定卡
US8841137B2 (en) 2010-02-25 2014-09-23 University Of Rochester Hybrid target analyte responsive polymer sensor with optical amplification
US9267919B1 (en) 2010-05-06 2016-02-23 The Florida International University Board Of Trustees Nanotip sensor
US9029168B2 (en) 2010-06-28 2015-05-12 The Trustees Of Princeton University Use and making of biosensors utilizing antimicrobial peptides for highly sensitive biological monitoring
US8920857B2 (en) 2010-12-22 2014-12-30 Michael T. Abramson System and method for detection of a contaminated beverage
US20130053666A1 (en) * 2011-08-26 2013-02-28 Dexcom, Inc. Polymer membranes for continuous analyte sensors
US9228972B2 (en) * 2012-02-22 2016-01-05 Advanced Diamond Technologies, Inc. Electroanalytical sensor based on nanocrystalline diamond electrodes and microelectrode arrays
CN102608185B (zh) * 2012-03-26 2014-02-19 清华大学 金电极及其制备方法
US8900879B2 (en) 2012-06-06 2014-12-02 National Taiwan University Sensor for detection of a target of interest

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US10849540B2 (en) 2020-12-01
EP2972333A4 (en) 2016-11-09
EP2972333B1 (en) 2018-09-19
US20160022185A1 (en) 2016-01-28
CN105190310B (zh) 2018-04-10
WO2014164654A1 (en) 2014-10-09
CN105190310A (zh) 2015-12-23

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