HK1211930A1 - Haptens of risperidone and paliperidone - Google Patents

Haptens of risperidone and paliperidone

Info

Publication number
HK1211930A1
HK1211930A1 HK15112817.9A HK15112817A HK1211930A1 HK 1211930 A1 HK1211930 A1 HK 1211930A1 HK 15112817 A HK15112817 A HK 15112817A HK 1211930 A1 HK1211930 A1 HK 1211930A1
Authority
HK
Hong Kong
Prior art keywords
paliperidone
risperidone
haptens
Prior art date
Application number
HK15112817.9A
Other languages
English (en)
Chinese (zh)
Inventor
Pieter Rik Haspeslagh
Maarten Vliegen
Eric Hryhorenko
Thomas R Decory
Banumathi Sankaran
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of HK1211930A1 publication Critical patent/HK1211930A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/44Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76Albumins
    • C07K14/77Ovalbumin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795Porphyrin- or corrin-ring-containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK15112817.9A 2012-08-21 2015-12-30 Haptens of risperidone and paliperidone HK1211930A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261691469P 2012-08-21 2012-08-21
PCT/US2013/055729 WO2014031601A1 (en) 2012-08-21 2013-08-20 Haptens of risperidone and paliperidone

Publications (1)

Publication Number Publication Date
HK1211930A1 true HK1211930A1 (en) 2016-06-03

Family

ID=49083786

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15112817.9A HK1211930A1 (en) 2012-08-21 2015-12-30 Haptens of risperidone and paliperidone

Country Status (12)

Country Link
US (1) US9012648B2 (pt)
EP (2) EP3415516B1 (pt)
JP (2) JP6131500B2 (pt)
CN (2) CN107082778A (pt)
AU (1) AU2013305936B2 (pt)
CA (1) CA2882560C (pt)
ES (2) ES2669565T3 (pt)
HK (1) HK1211930A1 (pt)
PL (2) PL2888263T3 (pt)
PT (2) PT3415516T (pt)
TR (1) TR201809424T4 (pt)
WO (1) WO2014031601A1 (pt)

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* Cited by examiner, † Cited by third party
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CA2882615C (en) 2012-08-21 2019-07-09 Ortho-Clinical Diagnostics, Inc. Antibodies to quetiapine and use thereof
AU2013305895B2 (en) 2012-08-21 2017-10-19 Saladax Biomedical Inc. Antibodies to olanzapine haptens and use thereof
AU2013305970B2 (en) 2012-08-21 2017-08-17 Saladax Biomedical Inc. Antibodies to aripiprazole haptens and use thereof
WO2014031603A1 (en) 2012-08-21 2014-02-27 Ortho-Clinical Diagnostics, Inc Antibodies to paliperidone haptens and use thereof
AU2013305879B2 (en) 2012-08-21 2017-10-12 Saladax Biomedical Inc. Antibodies to aripiprazole and use thereof
CA2882597C (en) 2012-08-21 2020-04-14 Ortho-Clinical Diagnostics, Inc. Antibodies to quetiapine haptens and use thereof
EP3933406A3 (en) 2012-08-21 2022-04-20 Janssen Pharmaceutica NV Antibodies to risperidone and use thereof
ES2669565T3 (es) * 2012-08-21 2018-05-28 Janssen Pharmaceutica Nv Haptenos de risperidona y paliperidona
CA2882563C (en) * 2012-08-21 2022-11-29 Eric Hryhorenko Antibodies to risperidone haptens and use thereof
JP6216926B2 (ja) 2012-08-21 2017-10-25 ヤンセン ファーマシューティカ エヌ.ベー. オランザピンに対する抗体及びその使用
PL2888234T3 (pl) 2012-08-21 2018-07-31 Janssen Pharmaceutica Nv Hapteny arypiprazolu i ich zastosowanie w testach immunologicznych
JP2015527365A (ja) 2012-08-21 2015-09-17 オルソ−クリニカル ダイアグノスティクス,インコーポレイティド パリペリドンに対する抗体及びその使用
JP6994461B2 (ja) 2015-12-17 2022-02-04 ヤンセン ファーマシューティカ エヌ.ベー. クエチアピンに対する抗体及びその使用
US10444250B2 (en) 2015-12-17 2019-10-15 Janssen Pharmaceutica Nv Antibodies to risperidone and use thereof
CN107137715B (zh) * 2017-04-26 2019-02-19 石家庄蒎格医药科技有限公司 一种帕利哌酮聚乙二醇缀合前药及制备
CN110938072A (zh) * 2019-10-30 2020-03-31 杭州博拓生物科技股份有限公司 一种利培酮人工抗原及其制备方法
CN112608310B (zh) * 2020-12-17 2022-03-29 北京丹大生物技术有限公司 一种利培酮和9-羟基利培酮半抗原、抗原和抗体以及其应用
CN114685470B (zh) * 2020-12-25 2023-08-18 长沙博源医疗科技有限公司 一种利培酮关键基团衍生物、免疫原、抗利培酮特异性抗体及其制备方法与应用
CN116003404A (zh) * 2022-12-14 2023-04-25 杭州同舟生物技术有限公司 一种利培酮人工半抗原、人工抗原及其制备方法和应用

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ATE198891T1 (de) 1992-05-29 2001-02-15 Lilly Co Eli Thienobenzodiazepinderivate zur behandlung von störungen des zentralnervensystems
US5395933A (en) 1992-08-07 1995-03-07 Eastman Kodak Company Carbamazepine hapten analogues
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EP1492794B1 (en) 2002-03-28 2007-12-12 Eli Lilly And Company Piperazine substituted aryl benzodiazepines and their use as dopamine receptor antagonists for the treatment of psychotic disorders
ES2285227T3 (es) 2002-08-05 2007-11-16 Eli Lilly And Company Arilbenzodiazepinas sustituidas con piperazina.
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US20080214808A1 (en) * 2005-04-25 2008-09-04 Thomas Frederik Ernestine Spittaels Preparation of Aseptic 3-[2-[4-((6-Fluoro-1,2-Benzisoxazol-3-Yl)-1-Piperidinyl]-6,7,8,9-Tetrahydro-9-Hydroxy-2-Methyl-4H-Pyrido[1,2-a]Pyrimidin-4-One Palmitate Ester
CN101245065B (zh) * 2007-02-14 2010-05-19 江苏恩华药业股份有限公司 制备苯并异噁唑衍生物的方法及其中间体
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US8088594B2 (en) 2010-03-16 2012-01-03 Saladax Biomedical Inc. Risperidone immunoassay
US8530413B2 (en) 2010-06-21 2013-09-10 Sanofi Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
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ES2669565T3 (es) * 2012-08-21 2018-05-28 Janssen Pharmaceutica Nv Haptenos de risperidona y paliperidona

Also Published As

Publication number Publication date
JP6667472B2 (ja) 2020-03-18
PL2888263T3 (pl) 2018-10-31
PL3415516T3 (pl) 2022-03-28
CN107082778A (zh) 2017-08-22
TR201809424T4 (tr) 2018-07-23
US20140155585A1 (en) 2014-06-05
JP2017149731A (ja) 2017-08-31
EP3415516B1 (en) 2021-12-15
EP2888263B1 (en) 2018-05-09
CA2882560A1 (en) 2014-02-27
JP2015526470A (ja) 2015-09-10
PT2888263T (pt) 2018-07-30
CA2882560C (en) 2020-10-27
ES2904838T3 (es) 2022-04-06
WO2014031601A1 (en) 2014-02-27
JP6131500B2 (ja) 2017-05-24
CN104755479A (zh) 2015-07-01
US9012648B2 (en) 2015-04-21
AU2013305936A1 (en) 2015-03-05
CN104755479B (zh) 2016-11-09
ES2669565T3 (es) 2018-05-28
PT3415516T (pt) 2022-01-28
AU2013305936B2 (en) 2017-08-03
EP3415516A1 (en) 2018-12-19
EP2888263A1 (en) 2015-07-01

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Legal Events

Date Code Title Description
AM Amended specification (according sect 146 of patent law)

Free format text: CORRECTION OF THE NAME OF APPLICANT FROM JANSSEN PHARMACEUTICA, N.V. T

Effective date: 20190318