HK1211491A1 - Ph-dependent controlled release pharmaceutical composition for non- opioids with resistance against the influence of ethanol ph - Google Patents

Ph-dependent controlled release pharmaceutical composition for non- opioids with resistance against the influence of ethanol ph

Info

Publication number
HK1211491A1
HK1211491A1 HK15112452.9A HK15112452A HK1211491A1 HK 1211491 A1 HK1211491 A1 HK 1211491A1 HK 15112452 A HK15112452 A HK 15112452A HK 1211491 A1 HK1211491 A1 HK 1211491A1
Authority
HK
Hong Kong
Prior art keywords
opioids
ethanol
influence
pharmaceutical composition
controlled release
Prior art date
Application number
HK15112452.9A
Other languages
English (en)
Chinese (zh)
Inventor
．巴爾
．福爾斯特
．雷恩納
．古特斯查克
Original Assignee
Evonik Roehm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evonik Roehm Gmbh filed Critical Evonik Roehm Gmbh
Publication of HK1211491A1 publication Critical patent/HK1211491A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK15112452.9A 2008-09-24 2015-12-17 Ph-dependent controlled release pharmaceutical composition for non- opioids with resistance against the influence of ethanol ph HK1211491A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/EP2008/062767 WO2010034344A1 (en) 2008-09-24 2008-09-24 Ph-dependent controlled release pharmaceutical composition for non-opioids with resistance against the influence of ethanol
CN2008801312249A CN102164589A (zh) 2008-09-24 2008-09-24 耐受乙醇影响的非阿片类药物的pH依赖性受控释放的药物组合物

Publications (1)

Publication Number Publication Date
HK1211491A1 true HK1211491A1 (en) 2016-05-27

Family

ID=40756228

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15112452.9A HK1211491A1 (en) 2008-09-24 2015-12-17 Ph-dependent controlled release pharmaceutical composition for non- opioids with resistance against the influence of ethanol ph

Country Status (14)

Country Link
US (1) US10933024B2 (ko)
EP (1) EP2326313B1 (ko)
JP (1) JP5453434B2 (ko)
KR (1) KR101535701B1 (ko)
CN (1) CN102164589A (ko)
BR (1) BRPI0823128B8 (ko)
CA (1) CA2738197C (ko)
ES (1) ES2537622T3 (ko)
HK (1) HK1211491A1 (ko)
IL (1) IL211305A (ko)
MX (1) MX2011003050A (ko)
PL (1) PL2326313T3 (ko)
SI (1) SI2326313T1 (ko)
WO (1) WO2010034344A1 (ko)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE032817T2 (en) 2009-03-18 2017-11-28 Evonik Roehm Gmbh Regulated release pharmaceutical composition comprising a coating containing neutral vinyl polymers and excipients and resistant to the influence of ethanol
BR112012028773A2 (pt) 2010-05-10 2016-07-19 Euro Celtique Sa composições farmacêuticas compreendendo hidromorfona e naloxona
US9993433B2 (en) 2010-05-10 2018-06-12 Euro-Celtique S.A. Manufacturing of active-free granules and tablets comprising the same
JP5840201B2 (ja) 2010-05-10 2016-01-06 ユーロ−セルティーク エス．エイ． 活性剤を負荷した顆粒と追加の活性剤の組合せ
PL2720681T3 (pl) 2011-06-17 2017-05-31 Evonik Röhm Gmbh Kompozycja powlekająca odpowiednia do farmaceutycznych lub nutraceutycznych postaci dawkowania
WO2012171575A1 (en) 2011-06-17 2012-12-20 Evonik Röhm Gmbh Coating composition suitable for pharmaceutical or nutraceutical dosage forms
WO2012171884A1 (en) * 2011-06-17 2012-12-20 Evonik Röhm Gmbh Gastric resistant pharmaceutical or nutraceutical composition with resistance against the influence of ethanol
US10195153B2 (en) 2013-08-12 2019-02-05 Pharmaceutical Manufacturing Research Services, Inc. Extruded immediate release abuse deterrent pill
US9814710B2 (en) 2013-11-13 2017-11-14 Euro-Celtique S.A. Hydromorphone and naloxone for treatment of pain and opioid bowel dysfunction syndrome
WO2015095391A1 (en) 2013-12-17 2015-06-25 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
US9492444B2 (en) 2013-12-17 2016-11-15 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
CA2955229C (en) 2014-07-17 2020-03-10 Pharmaceutical Manufacturing Research Services, Inc. Immediate release abuse deterrent liquid fill dosage form
ES2919874T3 (es) * 2014-09-24 2022-07-28 Vital Beverages Global Inc Composiciones y métodos para el suministro selectivo en el tubo gastrointestinal
EP3209282A4 (en) 2014-10-20 2018-05-23 Pharmaceutical Manufacturing Research Services, Inc. Extended release abuse deterrent liquid fill dosage form
EP3244881A4 (en) 2015-01-12 2018-08-15 Nano Pharmaceutical Laboratories LLC Layered sustained-release microbeads and methods of making the same
WO2016174664A1 (en) 2015-04-29 2016-11-03 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions
WO2019052845A1 (en) 2017-09-14 2019-03-21 Evonik Röhm Gmbh POLYMER AND PHARMACEUTICAL FORM WITH PROLONGED RELEASE PROPERTIES AND RESISTANCE TO THE INFLUENCE OF ETHANOL
MX2020009385A (es) 2018-03-09 2020-10-28 Evonik Operations Gmbh Mezcla de polimeros con resistencia a la influencia del etanol.
CN114983973B (zh) * 2022-05-31 2023-05-05 石家庄四药有限公司 一种乌拉地尔缓释胶囊及其制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4996047A (en) * 1988-11-02 1991-02-26 Richardson-Vicks, Inc. Sustained release drug-resin complexes
FR2655266B1 (fr) 1989-12-05 1992-04-03 Smith Kline French Lab Compositions pharmaceutiques a base de cimetidine.
US7374779B2 (en) 1999-02-26 2008-05-20 Lipocine, Inc. Pharmaceutical formulations and systems for improved absorption and multistage release of active agents
US20030118641A1 (en) 2000-07-27 2003-06-26 Roxane Laboratories, Inc. Abuse-resistant sustained-release opioid formulation
ES2230154T3 (es) 1999-08-27 2005-05-01 Southern Research Institute Composiciones inyectables de buprenorfina y su utilizacion para reduccion del consumo de heroina y alcohol.
DE10250543A1 (de) 2002-10-29 2004-05-19 Röhm GmbH & Co. KG Mehrschichtige Arzneiform
DE102005024614A1 (de) * 2005-05-25 2006-11-30 Röhm Gmbh Verwendung von Polymermischungen zur Herstellung von überzogenen Arzneiformen sowie Arzneiform mit polymerem Mischüberzug
WO2007085024A2 (en) * 2006-01-21 2007-07-26 Abbott Gmbh & Co. Kg Dosage form and method for the delivery of drugs of abuse
ES2385612T3 (es) * 2006-06-19 2012-07-27 Alpharma Pharmaceuticals, Llc Composiciones farmacéuticas
DE102006051020A1 (de) * 2006-10-26 2008-04-30 Evonik Röhm Gmbh Verwendung von (Meth)acrylat-Copolymeren in Retard-Arzneiformen zur Verringerung des Einflusses von Ethanol auf die Wirkstofffreisetzung
KR101424653B1 (ko) 2007-09-21 2014-08-06 에보니크 룀 게엠베하 에탄올의 영향에 대하여 내성을 가지는 ｐｈ-의존성 조절 방출 제약학적 오피오이드 조성물
US9555006B2 (en) 2007-09-21 2017-01-31 Evonik Roehm Gmbh PH-dependent controlled release pharmaceutical composition for non-opioids with resistance against the influence of ethanol

Also Published As

Publication number Publication date
JP2012503609A (ja) 2012-02-09
IL211305A (en) 2015-01-29
US10933024B2 (en) 2021-03-02
EP2326313A1 (en) 2011-06-01
IL211305A0 (en) 2011-04-28
PL2326313T3 (pl) 2015-08-31
CA2738197A1 (en) 2010-04-01
CA2738197C (en) 2016-01-05
BRPI0823128B1 (pt) 2019-05-07
WO2010034344A1 (en) 2010-04-01
SI2326313T1 (sl) 2015-06-30
US20110229562A1 (en) 2011-09-22
BRPI0823128A2 (pt) 2015-06-16
JP5453434B2 (ja) 2014-03-26
KR20110058836A (ko) 2011-06-01
ES2537622T3 (es) 2015-06-10
CN102164589A (zh) 2011-08-24
EP2326313B1 (en) 2015-03-04
BRPI0823128B8 (pt) 2022-07-05
MX2011003050A (es) 2011-04-11
KR101535701B1 (ko) 2015-07-09

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20230927