HK1210960A1 - 用於治療溶酶體貯積症的環糊精 - Google Patents
用於治療溶酶體貯積症的環糊精Info
- Publication number
- HK1210960A1 HK1210960A1 HK15111861.6A HK15111861A HK1210960A1 HK 1210960 A1 HK1210960 A1 HK 1210960A1 HK 15111861 A HK15111861 A HK 15111861A HK 1210960 A1 HK1210960 A1 HK 1210960A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- cyclodextrin
- treatment
- lysosomal storage
- storage diseases
- diseases
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/724—Cyclodextrins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A61K31/355—Tocopherols, e.g. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
- C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Materials Engineering (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Neurology (AREA)
- Emergency Medicine (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261679668P | 2012-08-03 | 2012-08-03 | |
PCT/US2013/053527 WO2014022841A1 (en) | 2012-08-03 | 2013-08-03 | Cyclodextrin for the treatment of lysosomal storage diseases |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1210960A1 true HK1210960A1 (zh) | 2016-05-13 |
Family
ID=49170855
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK15111861.6A HK1210960A1 (zh) | 2012-08-03 | 2015-12-02 | 用於治療溶酶體貯積症的環糊精 |
Country Status (8)
Country | Link |
---|---|
US (2) | US20150216895A1 (zh) |
EP (1) | EP2879714B1 (zh) |
JP (3) | JP2015524444A (zh) |
CN (2) | CN104684585A (zh) |
AU (2) | AU2013296170A1 (zh) |
CA (1) | CA2880880C (zh) |
HK (1) | HK1210960A1 (zh) |
WO (1) | WO2014022841A1 (zh) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2015524444A (ja) | 2012-08-03 | 2015-08-24 | ザ ユナイテッド ステイツ オブ アメリカ, アズ リプレゼンテッド バイ ザ セクレタリー, デパートメント オブ ヘルス アンド ヒューマン サービシーズ | ライソゾーム蓄積症を治療するためのシクロデキストリン |
JP6452115B2 (ja) | 2013-12-05 | 2019-01-16 | 国立大学法人 熊本大学 | コレステロール蓄積疾患治療薬 |
KR20170012555A (ko) | 2014-06-12 | 2017-02-02 | 더 유니버시티 오브 노트르 담 듀락 | 신경 질환 및 대뇌 상해의 치료를 위한 조성물 및 방법 |
CA2976449C (en) * | 2015-02-11 | 2022-08-09 | Icahn School Of Medicine At Mount Sinai | Benzenesulfonamide upregulators of npc1 for neimann-pick disease and other lysosomal storage disorders |
KR20180035787A (ko) * | 2015-06-10 | 2018-04-06 | 브이테스, 인코포레이티드 | 히드록시프로필 베타-시클로덱스트린 조성물 및 방법 |
MX2018008888A (es) * | 2016-01-21 | 2019-06-13 | Aten Porus Lifesciences | Polimeros a base de ciclodextrina, metodos, composiciones y aplicaciones de los mismos. |
CN109982718A (zh) | 2016-09-19 | 2019-07-05 | 阿托恩波罗斯生命科学 | 基于环糊精的聚合物、方法、组合物及其应用 |
JPWO2018199287A1 (ja) * | 2017-04-28 | 2020-03-12 | 国立大学法人京都大学 | クリスタリン網膜症の処置および/または予防方法 |
US20200268788A1 (en) * | 2017-08-28 | 2020-08-27 | Asdera Llc | Use of cyclodextrins in diseases and disorders involving phospholipid dysregulation |
AU2018341235A1 (en) | 2017-09-28 | 2020-05-07 | Asdera Llc | Use of cyclodextrins in diseases and disorders involving phospholipid dysregulation |
CN112996562A (zh) | 2018-10-29 | 2021-06-18 | 赛克洛治疗股份有限公司 | 治疗阿尔茨海默病的方法 |
JP2022518147A (ja) | 2019-01-03 | 2022-03-14 | アンダードッグ・ファーマシューティカルズ・インコーポレイテッド | シクロデキストリン二量体、それらの組成物、及びそれらの使用 |
JP7264452B2 (ja) * | 2019-04-15 | 2023-04-25 | 塩水港精糖株式会社 | ライソゾーム病の治療または予防のための医薬組成物 |
EP4208189A1 (en) * | 2020-09-03 | 2023-07-12 | University of Notre Dame du Lac | Therapy to stimulate hippocampal neural progenitors and adult neurogenesis |
US11958917B2 (en) | 2022-02-18 | 2024-04-16 | Beren Therapeutics P.B.C. | Compositions of hydroxypropyl-beta-cyclodextrin and methods of purifying the same |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4727064A (en) | 1984-04-25 | 1988-02-23 | The United States Of America As Represented By The Department Of Health And Human Services | Pharmaceutical preparations containing cyclodextrin derivatives |
US6407079B1 (en) | 1985-07-03 | 2002-06-18 | Janssen Pharmaceutica N.V. | Pharmaceutical compositions containing drugs which are instable or sparingly soluble in water and methods for their preparation |
US5376645A (en) | 1990-01-23 | 1994-12-27 | University Of Kansas | Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof |
US5262404A (en) | 1990-02-15 | 1993-11-16 | The Trustees Of The University Of Pennsylvania/Childrens Hospital Corporation | Cyclodextrin polymers and cyclodextrins immobilized on a solid surface |
EP0803243B1 (en) | 1996-04-24 | 2003-03-19 | Pfizer Inc. | Cyclodextrins and phenolic compounds in dental products |
FR2767834B1 (fr) | 1997-08-29 | 1999-12-03 | Inst Francais Du Petrole | Mono et di-derives de cyclodextrines, leurs synthese et purification et leur utilisation en support |
AU2001259725A1 (en) | 2000-05-15 | 2001-11-26 | The Procter And Gamble Company | Compositions comprising cyclodextrin derivatives |
US7442372B2 (en) * | 2003-08-29 | 2008-10-28 | Biomarin Pharmaceutical Inc. | Delivery of therapeutic compounds to the brain and other tissues |
WO2005112637A1 (en) * | 2004-05-14 | 2005-12-01 | Decode Chemistry, Inc. | Formulations for non-parenteral use including hydrophobic cyclodextrins |
EP1655034A1 (en) | 2004-10-10 | 2006-05-10 | Université de Liège | Use of cyclodextrin for treatment and prevention of bronchial inflammatory diseases. |
NZ573132A (en) * | 2006-06-06 | 2012-05-25 | Glaxo Group Ltd | Administration of anti-cd3 antibodies in the treatment of autoimmune diseases |
WO2010138802A2 (en) * | 2009-05-28 | 2010-12-02 | Cornell University | Compositions and their use for removing cholesterol |
US9044451B2 (en) * | 2010-07-19 | 2015-06-02 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Use of delta tocopherol for the treatment of lysosomal storage disorders |
WO2012100142A2 (en) * | 2011-01-20 | 2012-07-26 | Cornell University | Treatments for retinal disorders |
JP2015524444A (ja) | 2012-08-03 | 2015-08-24 | ザ ユナイテッド ステイツ オブ アメリカ, アズ リプレゼンテッド バイ ザ セクレタリー, デパートメント オブ ヘルス アンド ヒューマン サービシーズ | ライソゾーム蓄積症を治療するためのシクロデキストリン |
FR3014694B1 (fr) | 2013-12-13 | 2016-11-11 | Roquette Freres | Compositions a base de methyl-cyclodextrines pour le traitement et/ou la prevention de maladies par augmentation du taux de cholesterol-hdl |
-
2013
- 2013-08-03 JP JP2015525640A patent/JP2015524444A/ja active Pending
- 2013-08-03 WO PCT/US2013/053527 patent/WO2014022841A1/en active Application Filing
- 2013-08-03 CA CA2880880A patent/CA2880880C/en active Active
- 2013-08-03 CN CN201380052023.0A patent/CN104684585A/zh active Pending
- 2013-08-03 EP EP13762617.2A patent/EP2879714B1/en active Active
- 2013-08-03 AU AU2013296170A patent/AU2013296170A1/en not_active Abandoned
- 2013-08-03 CN CN201711057517.4A patent/CN107865968B/zh active Active
- 2013-08-03 US US14/419,471 patent/US20150216895A1/en not_active Abandoned
-
2015
- 2015-12-02 HK HK15111861.6A patent/HK1210960A1/zh unknown
-
2017
- 2017-06-12 US US15/620,753 patent/US11020422B2/en active Active
-
2018
- 2018-04-30 AU AU2018202964A patent/AU2018202964B2/en active Active
- 2018-06-20 JP JP2018116666A patent/JP2018162277A/ja active Pending
-
2020
- 2020-02-20 JP JP2020026808A patent/JP6858286B2/ja active Active
Also Published As
Publication number | Publication date |
---|---|
WO2014022841A1 (en) | 2014-02-06 |
US11020422B2 (en) | 2021-06-01 |
CN104684585A (zh) | 2015-06-03 |
JP2020097620A (ja) | 2020-06-25 |
EP2879714B1 (en) | 2021-04-14 |
AU2018202964B2 (en) | 2019-08-22 |
CN107865968A (zh) | 2018-04-03 |
US20180110798A1 (en) | 2018-04-26 |
AU2013296170A1 (en) | 2015-03-12 |
CA2880880C (en) | 2021-01-26 |
JP2015524444A (ja) | 2015-08-24 |
JP2018162277A (ja) | 2018-10-18 |
CN107865968B (zh) | 2021-03-05 |
AU2018202964A1 (en) | 2018-05-17 |
JP6858286B2 (ja) | 2021-04-14 |
US20150216895A1 (en) | 2015-08-06 |
EP2879714A1 (en) | 2015-06-10 |
CA2880880A1 (en) | 2014-02-06 |
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