HK1210193A1 - 在原核細胞周質中產生多肽的方法 - Google Patents

在原核細胞周質中產生多肽的方法

Info

Publication number
HK1210193A1
HK1210193A1 HK15111137.4A HK15111137A HK1210193A1 HK 1210193 A1 HK1210193 A1 HK 1210193A1 HK 15111137 A HK15111137 A HK 15111137A HK 1210193 A1 HK1210193 A1 HK 1210193A1
Authority
HK
Hong Kong
Prior art keywords
periplasm
polypeptides
production
prokaryotic cells
prokaryotic
Prior art date
Application number
HK15111137.4A
Other languages
English (en)
Inventor
Christian Schantz
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of HK1210193A1 publication Critical patent/HK1210193A1/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/145Extraction; Separation; Purification by extraction or solubilisation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/21Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
HK15111137.4A 2012-09-17 2015-11-11 在原核細胞周質中產生多肽的方法 HK1210193A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12184738 2012-09-17
PCT/EP2013/068993 WO2014041116A1 (en) 2012-09-17 2013-09-13 Method for the production of polypeptides in the periplasm of prokaryotic cells

Publications (1)

Publication Number Publication Date
HK1210193A1 true HK1210193A1 (zh) 2016-04-15

Family

ID=47115284

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15111137.4A HK1210193A1 (zh) 2012-09-17 2015-11-11 在原核細胞周質中產生多肽的方法

Country Status (15)

Country Link
US (1) US9926582B2 (zh)
EP (1) EP2895497B1 (zh)
JP (1) JP6325544B2 (zh)
KR (1) KR20150056552A (zh)
CN (1) CN104619716B (zh)
AU (1) AU2013314264B2 (zh)
BR (1) BR112015004415A2 (zh)
CA (1) CA2880469A1 (zh)
HK (1) HK1210193A1 (zh)
IL (1) IL237100A0 (zh)
MX (1) MX2015003028A (zh)
RU (1) RU2644652C2 (zh)
SG (1) SG11201501191XA (zh)
WO (1) WO2014041116A1 (zh)
ZA (1) ZA201500792B (zh)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2018329671B2 (en) * 2017-09-05 2023-12-07 Scarab Genomics, Llc Methods and compositions for improved expression of recombinant proteins
WO2022191223A1 (ja) * 2021-03-10 2022-09-15 株式会社カネカ 原核生物細胞から標的タンパク質を抽出する方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07184680A (ja) * 1993-12-28 1995-07-25 Mitsui Toatsu Chem Inc ペリプラズムタンパク質の回収法
WO2000049164A1 (en) * 1999-02-16 2000-08-24 Senesco, Inc. Dna encoding a plant lipase, transgenic plants and a method for controlling senescence in plants
CN1137139C (zh) * 2000-03-03 2004-02-04 上海复旦张江生物医药股份有限公司 重组淋巴毒素衍生物的生产工艺
ATE318890T1 (de) * 2000-12-14 2006-03-15 Genentech Inc Bakterielle wirtstämme
AU2003205623A1 (en) * 2002-01-18 2003-07-30 Cytos Biotechnology Ag Prion protein carrier-conjugates
US20060173167A1 (en) * 2003-08-13 2006-08-03 Gunter Stempfer Process for the purification of recombinant polypeptides
GB201001791D0 (en) * 2010-02-03 2010-03-24 Ucb Pharma Sa Process for obtaining antibodies
RU2488635C1 (ru) 2012-03-22 2013-07-27 Государственное бюджетное образовательное учреждение высшего профессионального образования Первый Московский государственный медицинский университет им. И.М. Сеченова Министерства здравоохранения и социального развития Российской Федерации (ГБОУ ВПО Первый МГМУ им. И.М. Сеченова Минздравсоцразвития Способ получения рекомбинантного антиангиогенного полипептида

Also Published As

Publication number Publication date
RU2644652C2 (ru) 2018-02-13
JP6325544B2 (ja) 2018-05-16
US9926582B2 (en) 2018-03-27
WO2014041116A1 (en) 2014-03-20
AU2013314264A1 (en) 2015-02-19
SG11201501191XA (en) 2015-04-29
ZA201500792B (en) 2016-01-27
AU2013314264B2 (en) 2017-08-31
CN104619716B (zh) 2018-05-11
CA2880469A1 (en) 2014-03-20
MX2015003028A (es) 2015-06-10
EP2895497A1 (en) 2015-07-22
JP2015528477A (ja) 2015-09-28
EP2895497B1 (en) 2017-11-22
RU2015114092A (ru) 2016-11-10
KR20150056552A (ko) 2015-05-26
IL237100A0 (en) 2015-03-31
CN104619716A (zh) 2015-05-13
US20150275260A1 (en) 2015-10-01
BR112015004415A2 (pt) 2017-07-04

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