HK1209726A1 - Protein kinase inhibitors - Google Patents

Protein kinase inhibitors

Info

Publication number
HK1209726A1
HK1209726A1 HK15110338.3A HK15110338A HK1209726A1 HK 1209726 A1 HK1209726 A1 HK 1209726A1 HK 15110338 A HK15110338 A HK 15110338A HK 1209726 A1 HK1209726 A1 HK 1209726A1
Authority
HK
Hong Kong
Prior art keywords
protein kinase
kinase inhibitors
inhibitors
protein
kinase
Prior art date
Application number
HK15110338.3A
Other languages
English (en)
Chinese (zh)
Inventor
Alain Laurent
Yannick Rose
Original Assignee
Pharmascience Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmascience Inc filed Critical Pharmascience Inc
Publication of HK1209726A1 publication Critical patent/HK1209726A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4162—1,2-Diazoles condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK15110338.3A 2012-07-06 2015-10-21 Protein kinase inhibitors HK1209726A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CA2782774A CA2782774A1 (fr) 2012-07-06 2012-07-06 Inhibiteurs de proteine kinase
PCT/CA2013/000612 WO2014005217A1 (fr) 2012-07-06 2013-07-03 Inhibiteurs de protéines kinases

Publications (1)

Publication Number Publication Date
HK1209726A1 true HK1209726A1 (en) 2016-04-08

Family

ID=49881186

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15110338.3A HK1209726A1 (en) 2012-07-06 2015-10-21 Protein kinase inhibitors

Country Status (12)

Country Link
US (2) US9447102B2 (fr)
EP (1) EP2870158B1 (fr)
JP (1) JP6190881B2 (fr)
KR (2) KR101903123B1 (fr)
CN (1) CN104718207B (fr)
BR (1) BR112014033056A2 (fr)
CA (2) CA2782774A1 (fr)
ES (1) ES2631228T3 (fr)
HK (1) HK1209726A1 (fr)
IN (1) IN2014MN02554A (fr)
RU (1) RU2679122C2 (fr)
WO (1) WO2014005217A1 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2782774A1 (fr) * 2012-07-06 2014-01-06 Pharmascience Inc. Inhibiteurs de proteine kinase
CA2833701A1 (fr) * 2013-11-19 2015-05-19 Pharmascience Inc. Inhibiteurs de proteine kinase
CA2833867A1 (fr) * 2013-11-21 2015-05-21 Pharmascience Inc. Inhibiteurs de proteine kinase
CA2834528A1 (fr) * 2013-11-26 2015-05-26 Pharmascience Inc. Inhibiteurs de proteines kinases
CN103787839B (zh) * 2014-01-21 2015-12-02 苏州昊帆生物科技有限公司 合成2,3,4,5,6-五氟苯酚的方法
EP3337805A4 (fr) * 2015-05-27 2019-04-03 Pharmascience Inc. Inhibiteurs de la famille des enzymes kinases tec
CN108431007B (zh) * 2015-09-16 2022-06-07 洛克索肿瘤学股份有限公司 用于治疗癌症的作为btk抑制剂的吡唑并嘧啶衍生物
WO2017134685A2 (fr) * 2016-02-02 2017-08-10 Sun Pharma Advanced Research Company Limited Nouveaux composés hydrazino utilisés comme inhibiteurs de btk
CN108368119B (zh) * 2016-08-17 2019-04-23 深圳市塔吉瑞生物医药有限公司 用于抑制酪氨酸激酶活性的稠合双环类化合物
CA3129665A1 (fr) 2019-03-21 2020-09-24 Onxeo Molecule dbait associee a un inhibiteur de kinase pour le traitement du cancer
KR20220098759A (ko) 2019-11-08 2022-07-12 인쎄름 (엥스띠뛰 나씨오날 드 라 쌍떼 에 드 라 흐쉐르슈 메디깔) 키나제 억제제에 대해 내성을 획득한 암의 치료 방법
WO2021148581A1 (fr) 2020-01-22 2021-07-29 Onxeo Nouvelle molécule dbait et son utilisation

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3736728A1 (de) * 1987-10-29 1989-05-11 Siemens Ag Druckertinte
EP0589335B1 (fr) * 1992-09-24 2003-06-18 Hoechst Aktiengesellschaft (1H)-1,2,3-Triazolo(4,5-d) pyrimidines substituées en N1, procédé pour leur préparation de même que leur utilisation comme moyens antiviraux
TR200201506T2 (tr) * 1999-09-17 2002-10-21 Abbott Gmbh & Co. Kg Terapötik maddeler olarak kinaz inhibitörleri
DE10031584A1 (de) * 2000-06-29 2002-01-10 Merck Patent Gmbh 5-Aminoalkyl-pyrazolo[4,3-d]pyrimidine
US20030199525A1 (en) * 2002-03-21 2003-10-23 Hirst Gavin C. Kinase inhibitors
EP2954900A1 (fr) 2007-03-28 2015-12-16 Pharmacyclics, Inc. Inhibiteurs de la tyrosine-kinase de bruton
CA2782774A1 (fr) * 2012-07-06 2014-01-06 Pharmascience Inc. Inhibiteurs de proteine kinase
LT2914296T (lt) * 2012-11-01 2018-09-25 Infinity Pharmaceuticals, Inc. Vėžio gydymas, panaudojant p13 kinazės izoformos moduliatorius

Also Published As

Publication number Publication date
WO2014005217A1 (fr) 2014-01-09
BR112014033056A2 (pt) 2017-06-27
EP2870158A4 (fr) 2015-12-09
IN2014MN02554A (fr) 2015-07-24
KR20180107328A (ko) 2018-10-01
RU2014151421A (ru) 2016-08-27
CA2878332C (fr) 2019-04-30
US20150344478A1 (en) 2015-12-03
EP2870158B1 (fr) 2017-05-31
CN104718207B (zh) 2017-08-15
US9447102B2 (en) 2016-09-20
KR20150041784A (ko) 2015-04-17
CA2878332A1 (fr) 2014-01-09
CN104718207A (zh) 2015-06-17
EP2870158A1 (fr) 2015-05-13
KR101903123B1 (ko) 2018-10-01
JP2015521987A (ja) 2015-08-03
JP6190881B2 (ja) 2017-08-30
US20160375027A1 (en) 2016-12-29
RU2679122C2 (ru) 2019-02-06
ES2631228T3 (es) 2017-08-29
CA2782774A1 (fr) 2014-01-06
US9795608B2 (en) 2017-10-24

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