HK1209632A1 - Irak inhibitors and uses thereof -1 (irak) - Google Patents

Irak inhibitors and uses thereof -1 (irak)

Info

Publication number
HK1209632A1
HK1209632A1 HK15110420.2A HK15110420A HK1209632A1 HK 1209632 A1 HK1209632 A1 HK 1209632A1 HK 15110420 A HK15110420 A HK 15110420A HK 1209632 A1 HK1209632 A1 HK 1209632A1
Authority
HK
Hong Kong
Prior art keywords
irak
inhibitors
irak inhibitors
Prior art date
Application number
HK15110420.2A
Other languages
English (en)
Chinese (zh)
Inventor
杰拉爾丁‧
‧哈里曼
羅納德‧
‧韋斯特
唐娜‧
‧羅梅羅
肖奈希‧羅賓遜
米‧雪萊
馬修‧戴維‧韋塞爾
杰里米‧羅伯特‧格林伍德
克雷格‧
‧馬斯
羅薩娜‧卡佩勒-利伯曼
Original Assignee
Nimbus Iris Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nimbus Iris Inc filed Critical Nimbus Iris Inc
Publication of HK1209632A1 publication Critical patent/HK1209632A1/xx

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
HK15110420.2A 2012-01-10 2015-10-22 Irak inhibitors and uses thereof -1 (irak) HK1209632A1 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201261585194P 2012-01-10 2012-01-10
US201261663227P 2012-06-22 2012-06-22
US201261682637P 2012-08-13 2012-08-13
US201261724695P 2012-11-09 2012-11-09
US201261734133P 2012-12-06 2012-12-06
PCT/US2013/020981 WO2013106535A1 (en) 2012-01-10 2013-01-10 Irak inhibitors and uses thereof

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BR112014017021A8 (pt) 2017-07-04
TW201728592A (zh) 2017-08-16
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CA2863259A1 (en) 2013-07-18
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CN104582705A (zh) 2015-04-29
EP2802330A4 (en) 2015-10-21
AU2013207972A1 (en) 2014-07-31
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EP2802330A1 (en) 2014-11-19
US20160193216A1 (en) 2016-07-07
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AU2017228639A1 (en) 2017-10-26

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