HK1209453A1 - Methods of generating mesenchymal stem cells which secrete neurotrophic factors - Google Patents

Methods of generating mesenchymal stem cells which secrete neurotrophic factors

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Publication number
HK1209453A1
HK1209453A1 HK15109965.5A HK15109965A HK1209453A1 HK 1209453 A1 HK1209453 A1 HK 1209453A1 HK 15109965 A HK15109965 A HK 15109965A HK 1209453 A1 HK1209453 A1 HK 1209453A1
Authority
HK
Hong Kong
Prior art keywords
methods
stem cells
mesenchymal stem
neurotrophic factors
secrete neurotrophic
Prior art date
Application number
HK15109965.5A
Other languages
English (en)
Chinese (zh)
Inventor
Yael Gothelf
Yosef Levy
Alex Burshtein
Original Assignee
Brainstorm Cell Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Brainstorm Cell Therapeutics Ltd filed Critical Brainstorm Cell Therapeutics Ltd
Publication of HK1209453A1 publication Critical patent/HK1209453A1/xx

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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
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HK15109965.5A 2012-08-06 2015-10-13 Methods of generating mesenchymal stem cells which secrete neurotrophic factors HK1209453A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261679822P 2012-08-06 2012-08-06
PCT/IL2013/050660 WO2014024183A1 (en) 2012-08-06 2013-08-04 Methods of generating mesenchymal stem cells which secrete neurotrophic factors

Publications (1)

Publication Number Publication Date
HK1209453A1 true HK1209453A1 (en) 2016-04-01

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HK15109965.5A HK1209453A1 (en) 2012-08-06 2015-10-13 Methods of generating mesenchymal stem cells which secrete neurotrophic factors

Country Status (10)

Country Link
US (3) US10046010B2 (xx)
EP (1) EP2880151B1 (xx)
JP (2) JP6362596B2 (xx)
BR (1) BR112015001435B1 (xx)
CA (1) CA2877223C (xx)
DK (1) DK2880151T3 (xx)
ES (1) ES2813407T3 (xx)
HK (1) HK1209453A1 (xx)
IL (1) IL261441B (xx)
WO (1) WO2014024183A1 (xx)

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TWI648273B (zh) 2013-02-15 2019-01-21 英商葛蘭素史克智慧財產發展有限公司 作為激酶抑制劑之雜環醯胺類（三）
JP6628253B2 (ja) 2014-02-11 2020-01-08 ブレインストーム セル セラペウティクス リミテッド 細胞の適性を判定する方法
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EP3286300B1 (en) 2015-04-24 2020-10-21 University of Copenhagen Isolation of bona fide pancreatic progenitor cells
CN105169486B (zh) * 2015-10-11 2018-04-03 温州医科大学 一种结合去细胞神经应用的神经修复材料
EP3455367A1 (en) 2016-05-09 2019-03-20 Sistemic Scotland Ltd Functional prediction of cellular functions by means of microrna expression profiling in mesenchymal stem cells
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WO2018015945A2 (en) 2016-07-18 2018-01-25 Brainstorm Cell Therapeutics Ltd Methods for treating amyotrophic lateral sclerosis (als)
SG11201901494UA (en) * 2016-09-12 2019-03-28 Genethon Acid-alpha glucosidase variants and uses thereof
IL270114B2 (en) * 2017-04-24 2024-01-01 Pluri Biotech Ltd Methods and compounds for the treatment of neurological diseases
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US11286462B2 (en) 2017-09-14 2022-03-29 University Of Kansas Materials and methods for generating therapeutic mesenchymal stem cells
MX2020002760A (es) * 2017-09-15 2020-07-20 Cynata Therapeutics Ltd Metodo para tratar la enfermedad alergica de las vias respiratorias (aad)/asma.
CA2983845C (en) 2017-10-26 2024-01-30 University Of Copenhagen Generation of glucose-responsive beta cells
CA3095716A1 (en) * 2018-04-10 2019-10-17 Brainstorm Cell Therapeutics Ltd. Cell-type specific exosomes and use thereof
US20200000886A1 (en) * 2018-06-29 2020-01-02 University Of Washington Engineering the rrm2 subunit of ribonucleotide reductase to resist degradation
CN111484978A (zh) * 2019-01-28 2020-08-04 深圳市第二人民医院 miR-140-5p过表达修饰的人脐带间充质干细胞、其治疗制剂、制备方法和应用
JPWO2020184729A1 (xx) 2019-03-14 2020-09-17
KR102323056B1 (ko) * 2019-05-02 2021-11-09 에스씨엠생명과학 주식회사 hPL 함유 배지에서 배양된 중간엽 줄기세포의 배양액을 포함하는 화장료 조성물
EP3985104A4 (en) * 2019-06-11 2023-04-12 Kyoto University PROCEDURE FOR GENERATING A KIDNEY INTERSTITIAL CELL
AU2021236144A1 (en) * 2020-03-11 2022-09-15 Remotor Therapeutics, Inc. Methods and materials for disseminating a protein throughout the central nervous system
KR20230128452A (ko) * 2020-10-26 2023-09-05 하다지트 메디칼 리서치 써비시즈 앤드 디벨롭먼트 리미티드 중간엽 줄기 세포 및 이의 배양
JPWO2022210514A1 (xx) 2021-03-30 2022-10-06
CN113367123B (zh) * 2021-06-07 2022-05-13 南京三生生物技术股份有限公司 一种细胞冻存方法
CN113789333B (zh) * 2021-09-07 2023-07-14 中国人民解放军军事科学院军事医学研究院 Chi3l1在调控hUC-MSCs抑制Th17分化介导的免疫调节作用上的应用
WO2023219655A1 (en) * 2022-05-13 2023-11-16 University Of Utah Research Foundation Gja1-20k to limited cardiac arrhythmias
CN116410921B (zh) * 2023-02-09 2024-01-23 北京益华生物科技有限公司 一种人源脐带间充质干细胞诱导培养基、诱导方法及应用

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