HK1208804A1 - Tumor tissue based biomarkers for bevacizumab combination therapies - Google Patents

Tumor tissue based biomarkers for bevacizumab combination therapies

Info

Publication number
HK1208804A1
HK1208804A1 HK15109509.8A HK15109509A HK1208804A1 HK 1208804 A1 HK1208804 A1 HK 1208804A1 HK 15109509 A HK15109509 A HK 15109509A HK 1208804 A1 HK1208804 A1 HK 1208804A1
Authority
HK
Hong Kong
Prior art keywords
tumor tissue
combination therapies
tissue based
based biomarkers
bevacizumab combination
Prior art date
Application number
HK15109509.8A
Other languages
English (en)
Chinese (zh)
Inventor
‧德爾馬
‧福恩茲勒
‧謝勒
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of HK1208804A1 publication Critical patent/HK1208804A1/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966Animal cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57419Specifically defined cancers of colon
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57446Specifically defined cancers of stomach or intestine
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475Assays involving growth factors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/71Assays involving receptors, cell surface antigens or cell surface determinants for growth factors; for growth regulators
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Hospice & Palliative Care (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Zoology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK15109509.8A 2010-01-19 2013-04-03 Tumor tissue based biomarkers for bevacizumab combination therapies HK1208804A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP10151109 2010-01-19

Publications (1)

Publication Number Publication Date
HK1208804A1 true HK1208804A1 (en) 2016-03-18

Family

ID=43770611

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15109509.8A HK1208804A1 (en) 2010-01-19 2013-04-03 Tumor tissue based biomarkers for bevacizumab combination therapies

Country Status (16)

Country Link
US (2) US20110182892A1 (es)
EP (2) EP2857040A1 (es)
JP (2) JP6057718B2 (es)
KR (1) KR101523419B1 (es)
CN (2) CN102711830A (es)
AU (1) AU2011208805A1 (es)
BR (1) BR112012016229A2 (es)
CA (2) CA2785774A1 (es)
HK (1) HK1208804A1 (es)
IL (1) IL220084A (es)
MX (1) MX2012007940A (es)
MY (1) MY172580A (es)
RU (1) RU2605282C2 (es)
SG (2) SG10201500479XA (es)
WO (1) WO2011089101A1 (es)
ZA (1) ZA201205014B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013539460A (ja) * 2010-08-13 2013-10-24 エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト ベバシズマブ併用療法のためのバイオマーカーとしてのニューロピリン
SG11201403927XA (en) 2012-01-13 2014-08-28 Genentech Inc Biological markers for identifying patients for treatment with vegf antagonists
US9116159B2 (en) 2012-05-22 2015-08-25 Regeneron Pharmaceuticals, Inc. VEGF-A121 assay
US20170051062A1 (en) * 2014-02-18 2017-02-23 Inserm (Institut National De La Sante Et De La Recherche Medicale) Methods and Pharmaceutical Compositions for the Treatment of Diseases Mediated by the NRP-1/OBR Complex Signaling Pathway
CN107076749B (zh) 2014-09-16 2020-12-29 瑞泽恩制药公司 转移性结直肠癌抗血管发生治疗相关预测和预后生物标志
RU2017120388A (ru) * 2014-11-14 2018-12-14 Дженентек, Инк. Прогнозирование ответа на антагонист vegf
WO2016115149A1 (en) * 2015-01-12 2016-07-21 Aveo Pharmaceuticals, Inc. Neuropilin-1 as a serum based biomarker
CN104531714A (zh) * 2015-01-23 2015-04-22 香港中文大学深圳研究院 适用于植物表达体系的表达贝伐单抗的基因、重组载体及产贝伐单抗植物的构建方法及应用
CN105424682A (zh) * 2015-11-17 2016-03-23 苏州浩欧博生物医药有限公司 一种贝伐单抗试剂盒及其抗药抗体试剂盒
WO2020165483A1 (es) * 2019-02-15 2020-08-20 Universidad de Córdoba Método de predicción de respuesta a tratamiento del cáncer con agentes antiangiogénicos
CN111773388B (zh) * 2019-04-04 2023-07-18 上海奥奇医药科技有限公司 A-失碳-5α雄甾烷化合物类药物与抗癌药物的联合应用
GR1009946B (el) * 2019-06-25 2021-03-04 ΕΝΟΡΑΣΙΣ ΑΝΩΝΥΜΗ ΕΜΠΟΡΙΚΗ ΕΤΑΙΡΕΙΑ ΦΑΡΜΑΚΕΥΤΙΚΩΝ ΚΑΙ ΙΑΤΡΙΚΩΝ ΥΛΙΚΩΝ ΚΑΙ ΜΗΧΑΝΗΜΑΤΩΝ με δ.τ. "ΕΝΟΡΑΣΙΣ Α.Ε." Οι συγκεντρωσεις της μπεβασιζουμαμπης σαν δεικτης στην ανταποκριση στη θεραπεια και στη συνολικη επιβιωση
RU2740361C1 (ru) * 2020-07-31 2021-01-13 Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр онкологии имени Н.Н. Блохина" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ онкологии им. Н.Н. Блохина" Минздрава России) Способ органосохраняющего лечения операбельного рака прямой кишки

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090275057A1 (en) * 2006-03-31 2009-11-05 Linke Steven P Diagnostic markers predictive of outcomes in colorectal cancer treatment and progression and methods of use thereof
EP2126126A2 (en) * 2007-01-18 2009-12-02 University Of Southern California Gene polymorphisms in vegf and vegf receptor 2 as markers for cancer therapy
EP2109686A2 (en) * 2007-01-18 2009-10-21 University Of Southern California Genetic markers for predicting responsiveness to combination therapy

Also Published As

Publication number Publication date
RU2605282C2 (ru) 2016-12-20
EP2857040A1 (en) 2015-04-08
JP2015178500A (ja) 2015-10-08
CA2785774A1 (en) 2011-07-18
IL220084A0 (en) 2012-09-24
BR112012016229A2 (pt) 2017-03-07
US20110182892A1 (en) 2011-07-28
KR20120123426A (ko) 2012-11-08
CN104474545A (zh) 2015-04-01
CN102711830A (zh) 2012-10-03
AU2011208805A1 (en) 2012-06-21
WO2011089101A1 (en) 2011-07-28
ZA201205014B (en) 2013-03-27
IL220084A (en) 2016-11-30
MX2012007940A (es) 2012-08-03
CA2891047A1 (en) 2011-07-18
JP6057718B2 (ja) 2017-01-11
MY172580A (en) 2019-12-04
US20140099302A1 (en) 2014-04-10
SG182520A1 (en) 2012-08-30
JP2013517258A (ja) 2013-05-16
EP2525821A1 (en) 2012-11-28
RU2012133472A (ru) 2014-02-27
SG10201500479XA (en) 2015-03-30
KR101523419B1 (ko) 2015-05-27

Similar Documents

Publication Publication Date Title
IL258740B (en) Combined liposome preparations for cancer treatment
HK1208804A1 (en) Tumor tissue based biomarkers for bevacizumab combination therapies
IL222481A0 (en) Combination therapy
EP2552323A4 (en) COMBINATION THERAPY
PT2829881T (pt) Diagnóstico para cancro colo-rectal
EP2542583B8 (en) Methods for treating breast cancer
GB201016139D0 (en) Cancer phosholipidome
GB2496805B (en) Compounds for photodynamic therapy
EP2748608A4 (en) LUNG CANCER TESTS
EP2635286A4 (en) METHOD FOR THE TREATMENT OF CANCER
EP2524702A4 (en) DIAGNOSTIC TO CANCER
IL222958A0 (en) Cancer treatment
GB201012590D0 (en) Methods for diagnosing cancer
HRP20181757T1 (hr) Kombinirana terapija za liječenje raka dojke
HK1179145A1 (en) Medical stapler
EP2715354A4 (en) CLEAR MARKING DURING A CANCER SURGERY
EP2585115A4 (en) ANTICANCER TREATMENT
GB201005394D0 (en) Therapy
GB201106630D0 (en) Cancer therapy
EP2629766A4 (en) COMBINATION THERAPY
GB201019034D0 (en) Treatment for tumors
GB201020513D0 (en) Cancer therapy
HK1169926A1 (en) Healthy shoe
ZA201208905B (en) Cancer therapy method
GB201118220D0 (en) Cancer therapy