HK1208731A1 - 用於檢測多特異性結合物的方法 - Google Patents

用於檢測多特異性結合物的方法

Info

Publication number
HK1208731A1
HK1208731A1 HK15109419.7A HK15109419A HK1208731A1 HK 1208731 A1 HK1208731 A1 HK 1208731A1 HK 15109419 A HK15109419 A HK 15109419A HK 1208731 A1 HK1208731 A1 HK 1208731A1
Authority
HK
Hong Kong
Prior art keywords
detection
multispecific binder
multispecific
binder
Prior art date
Application number
HK15109419.7A
Other languages
English (en)
Inventor
Kay-Gunnar Stubenrauch
Markus Zadak
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of HK1208731A1 publication Critical patent/HK1208731A1/zh

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G01N33/686—Anti-idiotype
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
HK15109419.7A 2012-07-13 2015-09-24 用於檢測多特異性結合物的方法 HK1208731A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12176342 2012-07-13
PCT/EP2013/064683 WO2014009474A1 (en) 2012-07-13 2013-07-11 Method for the detection of a multispecific binder

Publications (1)

Publication Number Publication Date
HK1208731A1 true HK1208731A1 (zh) 2016-03-11

Family

ID=48782335

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15109419.7A HK1208731A1 (zh) 2012-07-13 2015-09-24 用於檢測多特異性結合物的方法

Country Status (12)

Country Link
US (1) US9488662B2 (zh)
EP (1) EP2872893B1 (zh)
JP (1) JP6226976B2 (zh)
KR (1) KR20150038046A (zh)
CN (1) CN104471397B (zh)
BR (1) BR112015000665A2 (zh)
CA (1) CA2873829A1 (zh)
ES (1) ES2627482T3 (zh)
HK (1) HK1208731A1 (zh)
MX (1) MX346146B (zh)
RU (1) RU2636822C2 (zh)
WO (1) WO2014009474A1 (zh)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2810074B1 (en) 2012-02-01 2017-08-23 F. Hoffmann-La Roche AG Method for the detection of a binding partner of a multispecific binder
EP3066469B1 (en) * 2013-11-05 2017-10-11 Roche Diagnostics GmbH A method for determining the total amount and/or concentration of an analyte in the presence of a binding molecule as well as kits, compositions and uses relating thereto
JP6019254B2 (ja) 2014-04-23 2016-11-02 株式会社ニチレイバイオサイエンス 標的マーカー検出用組合せ物
AU2016344665C1 (en) * 2015-10-29 2023-07-27 F. Hoffmann-La Roche Ag Anti-variant Fc-region antibodies and methods of use
MX2018006030A (es) 2015-11-30 2018-08-01 Hoffmann La Roche Inmunoensayo para la determinacion de anticuerpos modificados en la region de fragmento cristalizable (fc).
WO2019235420A1 (ja) * 2018-06-04 2019-12-12 中外製薬株式会社 複合体を検出する方法
JP7273195B2 (ja) * 2019-05-13 2023-05-12 エフ． ホフマン－ラ ロシュ アーゲー 干渉抑制薬物動態イムノアッセイ

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EP0170302A1 (fr) 1984-06-27 1986-02-05 l'Association internationale à but scientifique, dite: Institut international de pathologie cellulaire et moléculaire Procédé de dosage immunologique d'une substance dans un échantillon liquide au moyen d'anticorps anti-idiotypiques
US5238808A (en) 1984-10-31 1993-08-24 Igen, Inc. Luminescent metal chelate labels and means for detection
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US5068088A (en) 1988-11-03 1991-11-26 Igen, Inc. Method and apparatus for conducting electrochemiluminescent measurements
IL100866A (en) 1991-02-06 1995-10-31 Igen Inc Luminescence test method and device based on magnetic tiny particles, containing many magnets
ATE225801T1 (de) 1992-07-13 2002-10-15 Bionebraska Inc Verfahren zur modifizierung rekombinanter polypeptide
GB9316369D0 (en) 1993-08-06 1993-09-22 Surface Active Ltd Diagnostic method
US6753189B1 (en) 1998-06-04 2004-06-22 Mizuho Medy Co., Ltd. Detection apparatus and method for the same
IL149171A0 (en) 1999-11-16 2002-11-10 Genentech Inc Elisa for vegf
DE60233744D1 (de) 2001-09-20 2009-10-29 Univ Texas Bestimmung der zirkulierenden therapeutischen antikörper, antigene sowie antigen-antikörper-komplexe mit elisa-tests
WO2006096697A2 (en) * 2005-03-08 2006-09-14 Tanox, Inc. Methods for determining the bivalency of protein and antibody therapeutics
DK2069798T3 (da) 2006-10-04 2014-06-16 Genentech Inc Elisa til vegf
EP1917854A1 (en) 2006-11-06 2008-05-07 F. Hoffmann-La Roche Ag Method for producing anti idiotypic antibodies
NZ614857A (en) * 2007-03-29 2015-04-24 Genmab As Bispecific antibodies and methods for production thereof
TWI570135B (zh) * 2007-04-27 2017-02-11 建南德克公司 高效、穩定且非免疫抑制之抗－ｃｄ４抗體
US8242247B2 (en) 2007-12-21 2012-08-14 Hoffmann-La Roche Inc. Bivalent, bispecific antibodies
US8227577B2 (en) 2007-12-21 2012-07-24 Hoffman-La Roche Inc. Bivalent, bispecific antibodies
US20090162359A1 (en) 2007-12-21 2009-06-25 Christian Klein Bivalent, bispecific antibodies
US9266967B2 (en) 2007-12-21 2016-02-23 Hoffmann-La Roche, Inc. Bivalent, bispecific antibodies
US20110195524A1 (en) * 2008-10-07 2011-08-11 Mats Inganas Semi-sequential assay for detection of an analyte in a sample
US8268314B2 (en) * 2008-10-08 2012-09-18 Hoffmann-La Roche Inc. Bispecific anti-VEGF/anti-ANG-2 antibodies
KR101431318B1 (ko) 2009-04-02 2014-08-20 로슈 글리카트 아게 전장 항체 및 단일쇄 ｆａｂ 단편을 포함하는 다중특이성 항체
SG175077A1 (en) 2009-04-07 2011-11-28 Roche Glycart Ag Trivalent, bispecific antibodies
KR101431319B1 (ko) 2009-05-27 2014-08-20 에프. 호프만-라 로슈 아게 삼중특이성 또는 사중특이성 항체
US9676845B2 (en) 2009-06-16 2017-06-13 Hoffmann-La Roche, Inc. Bispecific antigen binding proteins
US8703132B2 (en) 2009-06-18 2014-04-22 Hoffmann-La Roche, Inc. Bispecific, tetravalent antigen binding proteins
CN102207504A (zh) 2011-03-23 2011-10-05 北京华创远航科技有限公司 一种酶联检测试剂盒及其制备方法
BR112014011535A2 (pt) 2011-12-19 2017-05-09 Hoffmann La Roche método para a determinação in vitro e imunológica de presença da presença e/ou da quantidade de um parceiro de ligação, método in vitro e utilização de um anticorpo
EP2810074B1 (en) 2012-02-01 2017-08-23 F. Hoffmann-La Roche AG Method for the detection of a binding partner of a multispecific binder

Also Published As

Publication number Publication date
BR112015000665A2 (pt) 2017-06-27
JP2015522171A (ja) 2015-08-03
CN104471397B (zh) 2018-03-23
JP6226976B2 (ja) 2017-11-08
ES2627482T3 (es) 2017-07-28
US9488662B2 (en) 2016-11-08
MX2014014566A (es) 2015-02-20
CA2873829A1 (en) 2014-01-16
RU2015104737A (ru) 2016-08-27
US20150198608A1 (en) 2015-07-16
EP2872893B1 (en) 2017-03-29
CN104471397A (zh) 2015-03-25
EP2872893A1 (en) 2015-05-20
MX346146B (es) 2017-03-09
KR20150038046A (ko) 2015-04-08
RU2636822C2 (ru) 2017-11-28
WO2014009474A1 (en) 2014-01-16

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