HK1208621A1 - Combination of sglt2 inhibitor and anti-hypertension drug - Google Patents

Combination of sglt2 inhibitor and anti-hypertension drug Download PDF

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Publication number
HK1208621A1
HK1208621A1 HK15109273.2A HK15109273A HK1208621A1 HK 1208621 A1 HK1208621 A1 HK 1208621A1 HK 15109273 A HK15109273 A HK 15109273A HK 1208621 A1 HK1208621 A1 HK 1208621A1
Authority
HK
Hong Kong
Prior art keywords
diabetes
disease
medicament
hypertension
glucitol
Prior art date
Application number
HK15109273.2A
Other languages
English (en)
Chinese (zh)
Inventor
Naoki Kojima
Richard J. Roman
Noriyuki Miyata
Teisuke Takahashi
Hideki Tomoike
Takuya TAKEDA
Original Assignee
大正制药株式会社
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 大正制药株式会社 filed Critical 大正制药株式会社
Publication of HK1208621A1 publication Critical patent/HK1208621A1/xx

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/382Heterocyclic compounds having sulfur as a ring hetero atom having six-membered rings, e.g. thioxanthenes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/401Proline; Derivatives thereof, e.g. captopril
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK15109273.2A 2012-08-30 2013-08-30 Combination of sglt2 inhibitor and anti-hypertension drug HK1208621A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261695016P 2012-08-30 2012-08-30
US61/695,016 2012-08-30
PCT/JP2013/073300 WO2014034842A1 (ja) 2012-08-30 2013-08-30 Sglt2阻害薬と抗高血圧薬との組み合わせ

Publications (1)

Publication Number Publication Date
HK1208621A1 true HK1208621A1 (en) 2016-03-11

Family

ID=50183647

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15109273.2A HK1208621A1 (en) 2012-08-30 2013-08-30 Combination of sglt2 inhibitor and anti-hypertension drug

Country Status (17)

Country Link
US (1) US9320727B2 (enExample)
EP (1) EP2891499A4 (enExample)
JP (2) JP6198013B2 (enExample)
KR (1) KR20150046125A (enExample)
CN (1) CN104780942A (enExample)
AU (1) AU2013309904A1 (enExample)
BR (1) BR112015004012A2 (enExample)
CA (1) CA2883118A1 (enExample)
HK (1) HK1208621A1 (enExample)
IN (1) IN2015DN01975A (enExample)
MX (1) MX2015002572A (enExample)
PH (1) PH12015500434B1 (enExample)
RU (1) RU2015110979A (enExample)
SG (1) SG11201501510SA (enExample)
TW (1) TW201414472A (enExample)
WO (1) WO2014034842A1 (enExample)
ZA (1) ZA201502009B (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101943382B1 (ko) * 2017-09-19 2019-01-29 오토텔릭바이오 주식회사 Sglt-2 저해제 및 안지오텐신 수용체 차단제를 포함하는 의약 조성물
CN109806397A (zh) * 2017-11-20 2019-05-28 江苏恒瑞医药股份有限公司 Sglt2抑制剂与arb联合在制备治疗高血压等疾病的药物中的用途
KR102131359B1 (ko) * 2018-09-07 2020-07-07 오토텔릭바이오 주식회사 안정성이 향상된 의약 조성물
JP7659783B2 (ja) 2019-09-13 2025-04-10 国立大学法人富山大学 急性心不全における体液貯留改善薬
CA3180674A1 (en) * 2020-04-22 2021-10-28 Bayer Aktiengesellschaft Combination of finerenone and a sglt2 inhibitor for the treatment and/or prevention of cardiovascular and/or renal diseases
US20230346817A1 (en) * 2020-08-17 2023-11-02 Beijing Creatron Institute Of Pharmaceutical Research Co. Ltd. Composition and use of sglt-2 inhibitor and angiotensin receptor blockers
WO2022176981A1 (ja) * 2021-02-19 2022-08-25 大正製薬株式会社 経口フィルム製剤
KR102707874B1 (ko) * 2021-10-27 2024-09-25 주식회사 메디테이크 안지오텐신 수용체 차단제 및 sglt2 억제제를 포함하는 복합 조성물
EP4640223A1 (en) * 2022-12-20 2025-10-29 THPharm Corp. Pharmaceutical composition for prevention or treatment of cardiovascular disease, comprising sodium-glucose cotransporter-2 inhibitor and angiotensin ii receptor blocker

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH12000002657B1 (en) * 1999-10-12 2006-02-21 Bristol Myers Squibb Co C-aryl glucoside SGLT2 inhibitors
US6515117B2 (en) * 1999-10-12 2003-02-04 Bristol-Myers Squibb Company C-aryl glucoside SGLT2 inhibitors and method
DE102004048388A1 (de) 2004-10-01 2006-04-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg D-Pyranosyl-substituierte Phenyle, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung
TW200637839A (en) * 2005-01-07 2006-11-01 Taisho Pharmaceutical Co Ltd 1-thio-d-glucitol derivatives
JP5194588B2 (ja) * 2006-07-06 2013-05-08 大正製薬株式会社 1−チオ−d−グルシトール誘導体を有効成分として含有する糖尿病の予防又は治療剤
PE20090185A1 (es) * 2007-03-22 2009-02-28 Bristol Myers Squibb Co Formulaciones farmaceuticas que contienen un inhibidor sglt2
US20080287529A1 (en) * 2007-05-18 2008-11-20 Bristol-Myers Squibb Company Crystal structures of sglt2 inhibitors and processes for preparing same
WO2010048358A2 (en) * 2008-10-22 2010-04-29 Auspex Pharmaceutical, Inc. Ethoxyphenylmethyl inhibitors of sglt2
SG2014012462A (en) 2009-04-16 2014-05-29 Taisho Pharmaceutical Co Ltd Pharmaceutical compositions
US8685934B2 (en) * 2009-05-27 2014-04-01 Bristol-Myers Squibb Company Methods for treating extreme insulin resistance in patients resistant to previous treatment with other anti-diabetic drugs employing an SGLT2 inhibitor and compositions thereof

Also Published As

Publication number Publication date
EP2891499A4 (en) 2016-02-24
KR20150046125A (ko) 2015-04-29
BR112015004012A2 (pt) 2017-07-04
CN104780942A (zh) 2015-07-15
JPWO2014034842A1 (ja) 2016-08-08
TW201414472A (zh) 2014-04-16
JP2017186353A (ja) 2017-10-12
US9320727B2 (en) 2016-04-26
PH12015500434A1 (en) 2015-04-20
IN2015DN01975A (enExample) 2015-08-14
MX2015002572A (es) 2015-06-05
CA2883118A1 (en) 2014-03-06
ZA201502009B (en) 2016-07-27
RU2015110979A (ru) 2016-10-20
AU2013309904A1 (en) 2015-03-19
JP6198013B2 (ja) 2017-09-20
WO2014034842A1 (ja) 2014-03-06
SG11201501510SA (en) 2015-04-29
PH12015500434B1 (en) 2022-04-22
JP6358515B2 (ja) 2018-07-18
EP2891499A1 (en) 2015-07-08
US20150320721A1 (en) 2015-11-12

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