HK1208236A1 - Antigen binding proteins that bind ccr2 - Google Patents

Antigen binding proteins that bind ccr2 Download PDF

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Publication number
HK1208236A1
HK1208236A1 HK15108907.8A HK15108907A HK1208236A1 HK 1208236 A1 HK1208236 A1 HK 1208236A1 HK 15108907 A HK15108907 A HK 15108907A HK 1208236 A1 HK1208236 A1 HK 1208236A1
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Hong Kong
Prior art keywords
ccr2
antibodies
derivatives
polypeptides
methods
Prior art date
Application number
HK15108907.8A
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English (en)
Chinese (zh)
Inventor
Dingqiu HUANG
Barbara A. Swanson
Heyue Zhou
Guodi LU
Original Assignee
Sorrento Therapeutics, Inc.
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Publication date
Application filed by Sorrento Therapeutics, Inc. filed Critical Sorrento Therapeutics, Inc.
Publication of HK1208236A1 publication Critical patent/HK1208236A1/xx

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    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
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    • C07K16/30Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • C07K16/30Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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HK15108907.8A 2012-06-22 2013-06-21 Antigen binding proteins that bind ccr2 HK1208236A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261663496P 2012-06-22 2012-06-22
US61/663,496 2012-06-22
PCT/US2013/047192 WO2013192596A2 (en) 2012-06-22 2013-06-21 Antigen binding proteins that bind ccr2

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HK1208236A1 true HK1208236A1 (en) 2016-02-26

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US (3) US9315579B2 (https=)
EP (1) EP2864358B1 (https=)
JP (2) JP6438391B2 (https=)
CN (1) CN105051065A (https=)
CA (1) CA2877814A1 (https=)
HK (1) HK1208236A1 (https=)
WO (1) WO2013192596A2 (https=)

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WO2013192596A2 (en) * 2012-06-22 2013-12-27 Sorrento Therapeutics Inc. Antigen binding proteins that bind ccr2
DK3297438T3 (da) 2015-05-21 2022-01-17 Chemocentryx Inc Ccr2-modulatorer
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CA3293051A1 (en) 2017-09-25 2026-03-02 Chemocentryx, Inc. Combination therapy using a chemokine receptor 2 (ccr2) antagonist and a pd-1/pd-l1 inhibitor
EP3720881A1 (en) 2017-12-08 2020-10-14 Elstar Therapeutics, Inc. Multispecific molecules and uses thereof
CN112105353B (zh) * 2018-01-08 2024-04-19 凯莫森特里克斯股份有限公司 Ccr2拮抗剂治疗实体瘤的方法
US20190269664A1 (en) 2018-01-08 2019-09-05 Chemocentryx, Inc. Methods of treating solid tumors with ccr2 antagonists
EP3833762A4 (en) 2018-08-09 2022-09-28 Verseau Therapeutics, Inc. Oligonucleotide compositions for targeting ccr2 and csf1r and uses thereof
CN113164777B (zh) 2018-09-27 2024-12-13 马伦戈治疗公司 Csf1r/ccr2多特异性抗体
EP3883635A1 (en) 2018-11-19 2021-09-29 Progenity, Inc. Methods and devices for treating a disease with biotherapeutics
CN115666704B (zh) 2019-12-13 2025-09-26 比特比德科有限责任公司 用于将治疗剂递送至胃肠道的可摄取装置
MX2024004447A (es) 2021-10-27 2024-05-08 Granite Bio Ag Anticuerpos dirigidos a ccr2.
WO2024220548A2 (en) * 2023-04-17 2024-10-24 University Of Southern California Molecular-mri using ccr2-targeted micelles for detection of lymph node metastases
CN121399160A (zh) 2023-05-29 2026-01-23 花岗岩生物股份公司 靶向ccr2的抗体
WO2025231346A1 (en) * 2024-05-03 2025-11-06 The Wistar Institute Of Anatomy And Biology Anti-interferon-alpha and anti-interferon-beta antibodies, and methods of use thereof

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EP2864358A2 (en) 2015-04-29
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US20160289329A1 (en) 2016-10-06
EP2864358B1 (en) 2019-08-07
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WO2013192596A2 (en) 2013-12-27
JP6438391B2 (ja) 2018-12-12
US9315579B2 (en) 2016-04-19
CA2877814A1 (en) 2013-12-27
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