CN105051065A - 与ccr2结合的抗原结合蛋白 - Google Patents

与ccr2结合的抗原结合蛋白 Download PDF

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Publication number
CN105051065A
CN105051065A CN201380043633.4A CN201380043633A CN105051065A CN 105051065 A CN105051065 A CN 105051065A CN 201380043633 A CN201380043633 A CN 201380043633A CN 105051065 A CN105051065 A CN 105051065A
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seqidno
seq
ccr2
called
variable domain
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Chinese (zh)
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黄定秋
芭芭拉·A.·斯旺森
周贺钺
陆国弟
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Sorrento Therapeutics Inc
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Sorrento Therapeutics Inc
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CN201380043633.4A 2012-06-22 2013-06-21 与ccr2结合的抗原结合蛋白 Pending CN105051065A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261663496P 2012-06-22 2012-06-22
US61/663,496 2012-06-22
PCT/US2013/047192 WO2013192596A2 (en) 2012-06-22 2013-06-21 Antigen binding proteins that bind ccr2

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CN105051065A true CN105051065A (zh) 2015-11-11

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CN201380043633.4A Pending CN105051065A (zh) 2012-06-22 2013-06-21 与ccr2结合的抗原结合蛋白

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US (3) US9315579B2 (https=)
EP (1) EP2864358B1 (https=)
JP (2) JP6438391B2 (https=)
CN (1) CN105051065A (https=)
CA (1) CA2877814A1 (https=)
HK (1) HK1208236A1 (https=)
WO (1) WO2013192596A2 (https=)

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WO2017165125A1 (en) * 2016-03-24 2017-09-28 Millennium Pharmaceuticals, Inc. Use of a pd-1 antagonist and an anti-ccr2 antibody in the treatment of cancer

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BR112014013138B1 (pt) 2011-12-01 2022-06-28 Chemocentryx, Inc Compostos de anilinas substituídas como antagonistas de ccr(4) e composição farmacêutica compreendendo os mesmos
CN105050618B (zh) * 2012-06-21 2018-11-16 索伦托治疗有限公司 与c-Met结合的抗原结合蛋白
WO2013192596A2 (en) * 2012-06-22 2013-12-27 Sorrento Therapeutics Inc. Antigen binding proteins that bind ccr2
DK3297438T3 (da) 2015-05-21 2022-01-17 Chemocentryx Inc Ccr2-modulatorer
US20170348442A1 (en) 2016-06-02 2017-12-07 Washington University Compositions and methods for detecting ccr2 receptors
WO2018106945A1 (en) 2016-12-07 2018-06-14 Progenity Inc. Gastrointestinal tract detection methods, devices and systems
EP3554541B1 (en) 2016-12-14 2023-06-07 Biora Therapeutics, Inc. Treatment of a disease of the gastrointestinal tract with a chemokine/chemokine receptor inhibitor
CN110709422B (zh) * 2017-04-19 2023-12-26 马伦戈治疗公司 多特异性分子及其用途
CA3293051A1 (en) 2017-09-25 2026-03-02 Chemocentryx, Inc. Combination therapy using a chemokine receptor 2 (ccr2) antagonist and a pd-1/pd-l1 inhibitor
EP3720881A1 (en) 2017-12-08 2020-10-14 Elstar Therapeutics, Inc. Multispecific molecules and uses thereof
CN112105353B (zh) * 2018-01-08 2024-04-19 凯莫森特里克斯股份有限公司 Ccr2拮抗剂治疗实体瘤的方法
US20190269664A1 (en) 2018-01-08 2019-09-05 Chemocentryx, Inc. Methods of treating solid tumors with ccr2 antagonists
EP3833762A4 (en) 2018-08-09 2022-09-28 Verseau Therapeutics, Inc. Oligonucleotide compositions for targeting ccr2 and csf1r and uses thereof
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