HK1207991A1 - Bicyclic sulfone compounds for inhibition of rory activity and the treatment of disease ror - Google Patents

Bicyclic sulfone compounds for inhibition of rory activity and the treatment of disease ror

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Publication number
HK1207991A1
HK1207991A1 HK15108738.3A HK15108738A HK1207991A1 HK 1207991 A1 HK1207991 A1 HK 1207991A1 HK 15108738 A HK15108738 A HK 15108738A HK 1207991 A1 HK1207991 A1 HK 1207991A1
Authority
HK
Hong Kong
Prior art keywords
ror
inhibition
disease
treatment
sulfone compounds
Prior art date
Application number
HK15108738.3A
Other languages
English (en)
Chinese (zh)
Inventor
Thomas Aicher
Kenneth Barr
Vladimir Simov
William Thomas
Peter Toogood
Chad Van Huis
Original Assignee
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
Publication of HK1207991A1 publication Critical patent/HK1207991A1/xx

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    • C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C317/34—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring
    • C07C317/38—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring with the nitrogen atom of at least one amino group being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfones
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HK15108738.3A 2012-05-08 2015-09-08 Bicyclic sulfone compounds for inhibition of rory activity and the treatment of disease ror HK1207991A1 (en)

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JP2015517495A (ja) 2015-06-22
US20150126493A1 (en) 2015-05-07
US9266827B2 (en) 2016-02-23
MX363350B (es) 2019-03-20
AU2013259904A1 (en) 2014-10-02
KR20150013500A (ko) 2015-02-05
CA2871504C (fr) 2020-07-21
BR112014028023A2 (pt) 2017-06-27
EP2846794A1 (fr) 2015-03-18
CA2871504A1 (fr) 2013-11-14
MX2014013554A (es) 2015-07-14
CN104284657A (zh) 2015-01-14
JP6236067B2 (ja) 2017-11-22
WO2013169588A1 (fr) 2013-11-14
EP2846794A4 (fr) 2015-12-16
IN2014DN08025A (fr) 2015-05-01
RU2014149149A (ru) 2016-07-10

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