HK1207587A1 - A dual met - vegf modulator for treating osteolytic bone metastases met-vegf - Google Patents

A dual met - vegf modulator for treating osteolytic bone metastases met-vegf

Info

Publication number
HK1207587A1
HK1207587A1 HK15108354.6A HK15108354A HK1207587A1 HK 1207587 A1 HK1207587 A1 HK 1207587A1 HK 15108354 A HK15108354 A HK 15108354A HK 1207587 A1 HK1207587 A1 HK 1207587A1
Authority
HK
Hong Kong
Prior art keywords
met
vegf
bone metastases
dual
modulator
Prior art date
Application number
HK15108354.6A
Other languages
English (en)
Chinese (zh)
Inventor
Dana T Aftab
Original Assignee
Exelixis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Exelixis Inc filed Critical Exelixis Inc
Publication of HK1207587A1 publication Critical patent/HK1207587A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK15108354.6A 2012-05-02 2015-08-27 A dual met - vegf modulator for treating osteolytic bone metastases met-vegf HK1207587A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261641837P 2012-05-02 2012-05-02
PCT/US2013/039284 WO2013166296A1 (en) 2012-05-02 2013-05-02 A dual met - vegf modulator for treating osteolytic bone metastases

Publications (1)

Publication Number Publication Date
HK1207587A1 true HK1207587A1 (en) 2016-02-05

Family

ID=48428691

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15108354.6A HK1207587A1 (en) 2012-05-02 2015-08-27 A dual met - vegf modulator for treating osteolytic bone metastases met-vegf

Country Status (5)

Country Link
US (1) US9861624B2 (xx)
EP (1) EP2844254A1 (xx)
JP (2) JP2015515988A (xx)
HK (1) HK1207587A1 (xx)
WO (1) WO2013166296A1 (xx)

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WO2013059788A1 (en) 2011-10-20 2013-04-25 Exelixis, Inc. Process for preparing quinoline derivatives
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US10159666B2 (en) 2014-03-17 2018-12-25 Exelixis, Inc. Dosing of cabozantinib formulations
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EP3174854B1 (en) 2014-07-31 2022-08-24 Exelixis, Inc. Method of preparing fluorine-18 labeled cabozantinib and its analogs
MX2017001490A (es) 2014-08-05 2017-05-11 Exelixis Inc Combinaciones de farmacos para tratar mieloma multiple.
US11141413B2 (en) 2016-04-15 2021-10-12 Exelixis, Inc. Method of treating renal cell carcinoma using N-(4-(6,7-dimethoxyquinolin-4-yloxy)phenyl)-N′-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide, (2S)-hydroxybutanedioate
CR20200358A (es) 2018-01-26 2021-02-22 Exelixis Inc Compuestos para el tratamiento de trastornos dependientes de cinasas
WO2024110606A1 (en) * 2022-11-25 2024-05-30 Synthon B.V. A process for preparation of cabozantinib or tivozanib

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Also Published As

Publication number Publication date
US20150133494A1 (en) 2015-05-14
JP2015515988A (ja) 2015-06-04
WO2013166296A1 (en) 2013-11-07
US9861624B2 (en) 2018-01-09
EP2844254A1 (en) 2015-03-11
JP2018115174A (ja) 2018-07-26

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