HK1205764A1 - Tuberculosis biomarkers and uses thereof - Google Patents

Tuberculosis biomarkers and uses thereof Download PDF

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Publication number
HK1205764A1
HK1205764A1 HK15106261.2A HK15106261A HK1205764A1 HK 1205764 A1 HK1205764 A1 HK 1205764A1 HK 15106261 A HK15106261 A HK 15106261A HK 1205764 A1 HK1205764 A1 HK 1205764A1
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HK
Hong Kong
Prior art keywords
biomarkers
individual
methods
tables
used alone
Prior art date
Application number
HK15106261.2A
Other languages
English (en)
Chinese (zh)
Inventor
Ochsner Urs
G. Sterling David
Janjic Nebojsa
Original Assignee
Somalogic, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Somalogic, Inc. filed Critical Somalogic, Inc.
Publication of HK1205764A1 publication Critical patent/HK1205764A1/xx

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • G01N33/5695Mycobacteria
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2570/00Omics, e.g. proteomics, glycomics or lipidomics; Methods of analysis focusing on the entire complement of classes of biological molecules or subsets thereof, i.e. focusing on proteomes, glycomes or lipidomes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/60Complex ways of combining multiple protein biomarkers for diagnosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
HK15106261.2A 2012-04-13 2013-04-12 Tuberculosis biomarkers and uses thereof HK1205764A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261623732P 2012-04-13 2012-04-13
US61/623,732 2012-04-13
PCT/US2013/036447 WO2013155460A1 (en) 2012-04-13 2013-04-12 Tuberculosis biomarkers and uses thereof

Publications (1)

Publication Number Publication Date
HK1205764A1 true HK1205764A1 (en) 2015-12-24

Family

ID=49328218

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15106261.2A HK1205764A1 (en) 2012-04-13 2013-04-12 Tuberculosis biomarkers and uses thereof

Country Status (6)

Country Link
US (3) US20140155411A1 (enExample)
EP (1) EP2836608A4 (enExample)
JP (1) JP2015514227A (enExample)
CA (1) CA2867481A1 (enExample)
HK (1) HK1205764A1 (enExample)
WO (1) WO2013155460A1 (enExample)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HK1205764A1 (en) 2012-04-13 2015-12-24 Somalogic, Inc. Tuberculosis biomarkers and uses thereof
WO2015164616A1 (en) * 2014-04-24 2015-10-29 Somalogic, Inc. Biomarkers for detection of tuberculosis
WO2016182967A1 (en) * 2015-05-08 2016-11-17 Somalogic, Inc. Biomarkers for detection of tuberculosis risk
GB201519872D0 (en) * 2015-11-11 2015-12-23 Univ Cape Town And Ct For Infectious Disease Res Biomarkers for prospective determination of risk for development of active tuberculosis
GB201602305D0 (en) * 2016-02-09 2016-03-23 Medical Res Council And Imp Innovations Ltd TB Biomarkers
WO2017179008A1 (en) * 2016-04-15 2017-10-19 Stellenbosch University Host biomarkers for immunodiagnosis and monitoring of tuberculosis disease
US10607228B1 (en) * 2016-08-24 2020-03-31 Jpmorgan Chase Bank, N.A. Dynamic rule strategy and fraud detection system and method
US20200058369A1 (en) * 2016-11-02 2020-02-20 Biois Co., Ltd. Quantitative Cluster Analysis Method Of Target Protein By Using Next-Generation Sequencing And Use Thereof
WO2018106481A1 (en) * 2016-12-09 2018-06-14 Basil Leaf Technologies, Llc Computer-implemented methods, systems, and computer-readable media for diagnosing a condition
JP6812789B2 (ja) * 2016-12-28 2021-01-13 富士通株式会社 情報処理装置、情報処理プログラム、および情報処理方法
WO2019202448A1 (en) * 2018-04-16 2019-10-24 University Of Cape Town A three-protein proteomic biomarker for prospective determination of risk for development of active tuberculosis
JPWO2020162441A1 (enExample) * 2019-02-04 2020-08-13
PH12022550773A1 (en) * 2019-09-30 2023-05-03 Univ Cape Town Method for diagnosing tuberculosis in urine samples
CN112034176B (zh) * 2020-07-09 2022-08-30 中国工程物理研究院材料研究所 Cntn1作为长期低剂量电离辐射暴露诊断的分子标记物的用途
US20220026417A1 (en) * 2020-07-21 2022-01-27 Industry-University Cooperation Foundation, Catholic University of Pusan Method of simultaneously diagnosing active tuberculosis and latent tuberculosis infection using human whole blood sample-derived biomarker
CN112481369A (zh) * 2020-12-03 2021-03-12 中国医学科学院病原生物学研究所 Msrb1作为结核病诊断分子标识的用途
US11676726B2 (en) * 2021-06-22 2023-06-13 David Haase Apparatus and method for generating a treatment plan for salutogenesis
WO2023021262A1 (en) * 2021-08-17 2023-02-23 Scotland's Rural College Methods of determining animal phenotypes
CZ2021389A3 (cs) * 2021-08-20 2022-03-16 GeneSpector Innovations s.r.o. Způsob predikce závažnosti průběhu infekčního onemocnění a biomarker pro použití při provádění tohoto způsobu a monitoringu terapie infekčního onemocnění
CN114250310B (zh) * 2021-11-15 2023-12-08 四川大学华西医院 用于检测结核病的dna甲基化标志物、诊断模型、甲基化探针及试剂盒
CN115466797A (zh) * 2022-06-06 2022-12-13 四川大学华西第二医院 用于检测rs4770965和rs9507713的试剂在制备结核筛查试剂盒中的用途
WO2024091936A1 (en) * 2022-10-24 2024-05-02 Inflammatix, Inc. A fluidic device and methods for characterization of an infection or other condition
EP4467662A1 (en) 2023-05-26 2024-11-27 Forschungszentrum Borstel, Leibniz Lungenzentrum Method for predicting the time point of culture conversion in individuals
CN119689002B (zh) * 2025-02-25 2025-06-06 山东大学 用于预测胚胎反复种植失败的生物标志物组合、试剂盒及其应用和联合药物及其应用

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6143506A (en) * 1998-08-13 2000-11-07 The Research Foundation Of State Of Ny Diagnostic method for detection of periodontitis or peri-implantitis
AU2003241055A1 (en) * 2002-06-20 2004-01-06 Glaxo Group Limited Surrogate markers for the determination of the disease status of an individual infected by mycobacterium tuberculosis
US20060009378A1 (en) * 2002-11-14 2006-01-12 Itshak Golan Novel galectin sequences and compositions and methods utilizing same for treating or diagnosing arthritis and other chronic inflammatory diseases
KR20060015646A (ko) * 2003-06-13 2006-02-17 유니버시티 오브 피츠버그 면역, 혈액 및 염증성 질환의 모니터링 방법
GB0510511D0 (en) * 2005-05-23 2005-06-29 St Georges Entpr Ltd Diagnosis of tuberculosis
JP2007024631A (ja) 2005-07-14 2007-02-01 Human Science Shinko Zaidan 同位体標識法
DE602006020467D1 (de) * 2005-09-26 2011-04-14 Enzo Life Sciences Els Ag Antikörper gegen april als biomarker zur frühen prognose in lymphompatienten
US20070292869A1 (en) * 2006-03-02 2007-12-20 Ppd Biomarker Discovery Sciences, Llc Compositions and Methods for Analyzing Renal Cancer
US20080085524A1 (en) 2006-08-15 2008-04-10 Prometheus Laboratories Inc. Methods for diagnosing irritable bowel syndrome
KR100961926B1 (ko) * 2007-08-30 2010-06-10 서울대학교산학협력단 당뇨병성 망막병증 검출용 바이오 마커 조성물 및 진단키트
AT505727B1 (de) * 2007-09-04 2009-06-15 Univ Innsbruck Verfahren zur diagnose des metabolischen syndroms
US20110129817A1 (en) * 2009-11-30 2011-06-02 Baylor Research Institute Blood transcriptional signature of active versus latent mycobacterium tuberculosis infection
MX2010014556A (es) * 2008-06-25 2011-07-28 Baylor Res Inst Firma transcripcional de sangre por infeccion de mycobacterium tuberculosis.
EP2430451B1 (en) * 2009-05-14 2014-08-13 The Chancellors, Masters and Scholars of the University of Oxford Clinical diagnosis of hepatic fibrosis / cirrhosis using low abundant human plasma protein biomarkers
MX2012010554A (es) * 2010-03-31 2012-10-05 Firmenich & Cie Preparacion de capsulas solidas que comprenden sabores.
EP2558586B1 (en) * 2010-04-12 2016-10-12 Somalogic, Inc. APTAMERS TO ß-NGF AND THEIR USE IN TREATING ß-NGF MEDIATED DISEASES AND DISORDERS
HK1205764A1 (en) 2012-04-13 2015-12-24 Somalogic, Inc. Tuberculosis biomarkers and uses thereof
CN103065065A (zh) * 2012-11-18 2013-04-24 浙江大学 一种活动性肺结核蛋白表达差异质谱模型及构建方法

Also Published As

Publication number Publication date
EP2836608A4 (en) 2016-02-24
US20180128839A1 (en) 2018-05-10
US20140155411A1 (en) 2014-06-05
CA2867481A1 (en) 2013-10-17
WO2013155460A1 (en) 2013-10-17
EP2836608A1 (en) 2015-02-18
JP2015514227A (ja) 2015-05-18
US10408847B2 (en) 2019-09-10
US20160109462A1 (en) 2016-04-21

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