CA2867481A1 - Tuberculosis biomarkers and uses thereof - Google Patents
Tuberculosis biomarkers and uses thereof Download PDFInfo
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- CA2867481A1 CA2867481A1 CA2867481A CA2867481A CA2867481A1 CA 2867481 A1 CA2867481 A1 CA 2867481A1 CA 2867481 A CA2867481 A CA 2867481A CA 2867481 A CA2867481 A CA 2867481A CA 2867481 A1 CA2867481 A1 CA 2867481A1
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- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
- G01N33/5695—Mycobacteria
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- C12Q2600/00—Oligonucleotides characterized by their use
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
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- G—PHYSICS
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- G—PHYSICS
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- G01N2800/00—Detection or diagnosis of diseases
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- G—PHYSICS
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- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis
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| US201261623732P | 2012-04-13 | 2012-04-13 | |
| US61/623,732 | 2012-04-13 | ||
| PCT/US2013/036447 WO2013155460A1 (en) | 2012-04-13 | 2013-04-12 | Tuberculosis biomarkers and uses thereof |
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| HK1205764A1 (en) | 2012-04-13 | 2015-12-24 | Somalogic, Inc. | Tuberculosis biomarkers and uses thereof |
| WO2015164616A1 (en) * | 2014-04-24 | 2015-10-29 | Somalogic, Inc. | Biomarkers for detection of tuberculosis |
| WO2016182967A1 (en) * | 2015-05-08 | 2016-11-17 | Somalogic, Inc. | Biomarkers for detection of tuberculosis risk |
| GB201519872D0 (en) * | 2015-11-11 | 2015-12-23 | Univ Cape Town And Ct For Infectious Disease Res | Biomarkers for prospective determination of risk for development of active tuberculosis |
| GB201602305D0 (en) * | 2016-02-09 | 2016-03-23 | Medical Res Council And Imp Innovations Ltd | TB Biomarkers |
| WO2017179008A1 (en) * | 2016-04-15 | 2017-10-19 | Stellenbosch University | Host biomarkers for immunodiagnosis and monitoring of tuberculosis disease |
| US10607228B1 (en) * | 2016-08-24 | 2020-03-31 | Jpmorgan Chase Bank, N.A. | Dynamic rule strategy and fraud detection system and method |
| US20200058369A1 (en) * | 2016-11-02 | 2020-02-20 | Biois Co., Ltd. | Quantitative Cluster Analysis Method Of Target Protein By Using Next-Generation Sequencing And Use Thereof |
| WO2018106481A1 (en) * | 2016-12-09 | 2018-06-14 | Basil Leaf Technologies, Llc | Computer-implemented methods, systems, and computer-readable media for diagnosing a condition |
| JP6812789B2 (ja) * | 2016-12-28 | 2021-01-13 | 富士通株式会社 | 情報処理装置、情報処理プログラム、および情報処理方法 |
| WO2019202448A1 (en) * | 2018-04-16 | 2019-10-24 | University Of Cape Town | A three-protein proteomic biomarker for prospective determination of risk for development of active tuberculosis |
| JPWO2020162441A1 (enExample) * | 2019-02-04 | 2020-08-13 | ||
| PH12022550773A1 (en) * | 2019-09-30 | 2023-05-03 | Univ Cape Town | Method for diagnosing tuberculosis in urine samples |
| CN112034176B (zh) * | 2020-07-09 | 2022-08-30 | 中国工程物理研究院材料研究所 | Cntn1作为长期低剂量电离辐射暴露诊断的分子标记物的用途 |
| US20220026417A1 (en) * | 2020-07-21 | 2022-01-27 | Industry-University Cooperation Foundation, Catholic University of Pusan | Method of simultaneously diagnosing active tuberculosis and latent tuberculosis infection using human whole blood sample-derived biomarker |
| CN112481369A (zh) * | 2020-12-03 | 2021-03-12 | 中国医学科学院病原生物学研究所 | Msrb1作为结核病诊断分子标识的用途 |
| US11676726B2 (en) * | 2021-06-22 | 2023-06-13 | David Haase | Apparatus and method for generating a treatment plan for salutogenesis |
| WO2023021262A1 (en) * | 2021-08-17 | 2023-02-23 | Scotland's Rural College | Methods of determining animal phenotypes |
| CZ2021389A3 (cs) * | 2021-08-20 | 2022-03-16 | GeneSpector Innovations s.r.o. | Způsob predikce závažnosti průběhu infekčního onemocnění a biomarker pro použití při provádění tohoto způsobu a monitoringu terapie infekčního onemocnění |
| CN114250310B (zh) * | 2021-11-15 | 2023-12-08 | 四川大学华西医院 | 用于检测结核病的dna甲基化标志物、诊断模型、甲基化探针及试剂盒 |
| CN115466797A (zh) * | 2022-06-06 | 2022-12-13 | 四川大学华西第二医院 | 用于检测rs4770965和rs9507713的试剂在制备结核筛查试剂盒中的用途 |
| WO2024091936A1 (en) * | 2022-10-24 | 2024-05-02 | Inflammatix, Inc. | A fluidic device and methods for characterization of an infection or other condition |
| EP4467662A1 (en) | 2023-05-26 | 2024-11-27 | Forschungszentrum Borstel, Leibniz Lungenzentrum | Method for predicting the time point of culture conversion in individuals |
| CN119689002B (zh) * | 2025-02-25 | 2025-06-06 | 山东大学 | 用于预测胚胎反复种植失败的生物标志物组合、试剂盒及其应用和联合药物及其应用 |
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| US6143506A (en) * | 1998-08-13 | 2000-11-07 | The Research Foundation Of State Of Ny | Diagnostic method for detection of periodontitis or peri-implantitis |
| AU2003241055A1 (en) * | 2002-06-20 | 2004-01-06 | Glaxo Group Limited | Surrogate markers for the determination of the disease status of an individual infected by mycobacterium tuberculosis |
| US20060009378A1 (en) * | 2002-11-14 | 2006-01-12 | Itshak Golan | Novel galectin sequences and compositions and methods utilizing same for treating or diagnosing arthritis and other chronic inflammatory diseases |
| KR20060015646A (ko) * | 2003-06-13 | 2006-02-17 | 유니버시티 오브 피츠버그 | 면역, 혈액 및 염증성 질환의 모니터링 방법 |
| GB0510511D0 (en) * | 2005-05-23 | 2005-06-29 | St Georges Entpr Ltd | Diagnosis of tuberculosis |
| JP2007024631A (ja) | 2005-07-14 | 2007-02-01 | Human Science Shinko Zaidan | 同位体標識法 |
| DE602006020467D1 (de) * | 2005-09-26 | 2011-04-14 | Enzo Life Sciences Els Ag | Antikörper gegen april als biomarker zur frühen prognose in lymphompatienten |
| US20070292869A1 (en) * | 2006-03-02 | 2007-12-20 | Ppd Biomarker Discovery Sciences, Llc | Compositions and Methods for Analyzing Renal Cancer |
| US20080085524A1 (en) | 2006-08-15 | 2008-04-10 | Prometheus Laboratories Inc. | Methods for diagnosing irritable bowel syndrome |
| KR100961926B1 (ko) * | 2007-08-30 | 2010-06-10 | 서울대학교산학협력단 | 당뇨병성 망막병증 검출용 바이오 마커 조성물 및 진단키트 |
| AT505727B1 (de) * | 2007-09-04 | 2009-06-15 | Univ Innsbruck | Verfahren zur diagnose des metabolischen syndroms |
| US20110129817A1 (en) * | 2009-11-30 | 2011-06-02 | Baylor Research Institute | Blood transcriptional signature of active versus latent mycobacterium tuberculosis infection |
| MX2010014556A (es) * | 2008-06-25 | 2011-07-28 | Baylor Res Inst | Firma transcripcional de sangre por infeccion de mycobacterium tuberculosis. |
| EP2430451B1 (en) * | 2009-05-14 | 2014-08-13 | The Chancellors, Masters and Scholars of the University of Oxford | Clinical diagnosis of hepatic fibrosis / cirrhosis using low abundant human plasma protein biomarkers |
| MX2012010554A (es) * | 2010-03-31 | 2012-10-05 | Firmenich & Cie | Preparacion de capsulas solidas que comprenden sabores. |
| EP2558586B1 (en) * | 2010-04-12 | 2016-10-12 | Somalogic, Inc. | APTAMERS TO ß-NGF AND THEIR USE IN TREATING ß-NGF MEDIATED DISEASES AND DISORDERS |
| HK1205764A1 (en) | 2012-04-13 | 2015-12-24 | Somalogic, Inc. | Tuberculosis biomarkers and uses thereof |
| CN103065065A (zh) * | 2012-11-18 | 2013-04-24 | 浙江大学 | 一种活动性肺结核蛋白表达差异质谱模型及构建方法 |
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| EP2836608A4 (en) | 2016-02-24 |
| US20180128839A1 (en) | 2018-05-10 |
| US20140155411A1 (en) | 2014-06-05 |
| WO2013155460A1 (en) | 2013-10-17 |
| EP2836608A1 (en) | 2015-02-18 |
| HK1205764A1 (en) | 2015-12-24 |
| JP2015514227A (ja) | 2015-05-18 |
| US10408847B2 (en) | 2019-09-10 |
| US20160109462A1 (en) | 2016-04-21 |
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