HK1205139A1 - Protease resistant mutants of stromal cell derived factor-1 in the repair of tissue damage - Google Patents
Protease resistant mutants of stromal cell derived factor-1 in the repair of tissue damageInfo
- Publication number
- HK1205139A1 HK1205139A1 HK15105619.3A HK15105619A HK1205139A1 HK 1205139 A1 HK1205139 A1 HK 1205139A1 HK 15105619 A HK15105619 A HK 15105619A HK 1205139 A1 HK1205139 A1 HK 1205139A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- repair
- tissue damage
- cell derived
- stromal cell
- derived factor
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/521—Chemokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/735—Fusion polypeptide containing domain for protein-protein interaction containing a domain for self-assembly, e.g. a viral coat protein (includes phage display)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Diabetes (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Emergency Medicine (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Dermatology (AREA)
- Neurology (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US85344106P | 2006-10-23 | 2006-10-23 | |
US92935307P | 2007-06-22 | 2007-06-22 | |
US11/976,032 US7696309B2 (en) | 2006-10-23 | 2007-10-19 | Protease resistant mutants of stromal cell derived factor-1 in the repair of tissue damage |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1205139A1 true HK1205139A1 (en) | 2015-12-11 |
Family
ID=39318162
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK10103057.2A HK1136211A1 (en) | 2006-10-23 | 2010-03-23 | Protease resistant mutants of stromal cell derived factor-1 in the repair of tissue damage |
HK15105619.3A HK1205139A1 (en) | 2006-10-23 | 2015-06-15 | Protease resistant mutants of stromal cell derived factor-1 in the repair of tissue damage |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK10103057.2A HK1136211A1 (en) | 2006-10-23 | 2010-03-23 | Protease resistant mutants of stromal cell derived factor-1 in the repair of tissue damage |
Country Status (10)
Country | Link |
---|---|
US (6) | US7696309B2 (xx) |
EP (2) | EP2094288A4 (xx) |
JP (2) | JP5695318B2 (xx) |
CN (2) | CN104211800B (xx) |
AU (1) | AU2007309479A1 (xx) |
CA (1) | CA2667280C (xx) |
HK (2) | HK1136211A1 (xx) |
IL (2) | IL198021A (xx) |
NZ (1) | NZ576188A (xx) |
WO (1) | WO2008051505A2 (xx) |
Families Citing this family (22)
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US20050260258A1 (en) | 2003-12-18 | 2005-11-24 | The Texas A&M University System | Use of vitelline protein B as a microencapsulating additive |
US7696309B2 (en) | 2006-10-23 | 2010-04-13 | The Brigham And Women's Hospital, Inc. | Protease resistant mutants of stromal cell derived factor-1 in the repair of tissue damage |
WO2010101628A2 (en) * | 2009-03-02 | 2010-09-10 | Massachusetts Institute Of Technology | Methods and products for in vivo enzyme profiling |
US9308277B2 (en) * | 2010-02-25 | 2016-04-12 | Mesoblast International Sàrl | Protease-resistant mutants of stromal cell derived factor-1 in the repair of tissue damage |
US8741833B2 (en) * | 2010-07-16 | 2014-06-03 | Massachusetts Institute Of Technology | Self-assembling peptides incorporating modifications and methods of use thereof |
WO2012027170A1 (en) * | 2010-08-23 | 2012-03-01 | Provasculon, Inc. | Methods for repairing tissue damage using protease-resistant mutants of stromal cell derived factor-1 |
WO2012125808A1 (en) * | 2011-03-15 | 2012-09-20 | Massachusetts Institute Of Technology | Multiplexed detection with isotope-coded reporters |
CA2838155C (en) | 2011-06-07 | 2021-10-19 | Provasculon, Inc. | Methods for repairing tissue damage using protease-resistant mutants of stromal cell derived factor-1 |
CN103740662B (zh) * | 2012-05-10 | 2015-08-19 | 江南大学 | 一种提高酶热稳定性的方法 |
EP3004374B1 (en) | 2013-06-07 | 2020-08-12 | Massachusetts Institute of Technology | Affinity-based detection of ligand-encoded synthetic biomarkers |
CA2933620A1 (en) * | 2013-12-13 | 2015-06-18 | Mesoblast International Sarl | Methods for repairing tissue damage using protease-resistant mutants of stromal cell derived factor-1 |
CN104650192B (zh) * | 2015-03-26 | 2017-06-23 | 罗忠礼 | 一类能用于修复子宫和保护心肌的自组装短肽及其应用 |
WO2017177115A1 (en) | 2016-04-08 | 2017-10-12 | Massachusetts Institute Of Technology | Methods to specifically profile protease activity at lymph nodes |
US11428689B2 (en) | 2016-05-05 | 2022-08-30 | Massachusetts Institute Of Technology | Methods and uses for remotely triggered protease activity measurements |
AU2018248327A1 (en) | 2017-04-07 | 2019-10-17 | Massachusetts Institute Of Technology | Methods to spatially profile protease activity in tissue and sections |
WO2019173332A1 (en) | 2018-03-05 | 2019-09-12 | Massachusetts Institute Of Technology | Inhalable nanosensors with volatile reporters and uses thereof |
CN109321481B (zh) * | 2018-11-22 | 2020-12-29 | 湖南汇升生物科技有限公司 | 一种生麦芽糖淀粉酶生产菌株 |
CN109486792B (zh) * | 2018-11-22 | 2019-12-10 | 湖南汇升生物科技有限公司 | 一种生麦芽糖淀粉酶突变体的制备及其应用 |
CN109439641B (zh) * | 2018-11-22 | 2020-12-29 | 湖南汇升生物科技有限公司 | 一种生麦芽糖淀粉酶生产菌株的应用 |
CN109234339B (zh) * | 2018-11-22 | 2020-12-29 | 湖南汇升生物科技有限公司 | 一种高纯度结晶麦芽糖的生产方法 |
EP3892330A4 (en) * | 2018-12-04 | 2022-10-26 | Chugai Seiyaku Kabushiki Kaisha | CXCR3 LIGAND |
US11835522B2 (en) | 2019-01-17 | 2023-12-05 | Massachusetts Institute Of Technology | Sensors for detecting and imaging of cancer metastasis |
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US5670483A (en) | 1992-12-28 | 1997-09-23 | Massachusetts Insititute Of Technology | Stable macroscopic membranes formed by self-assembly of amphiphilic peptides and uses therefor |
JP3367581B2 (ja) | 1993-10-14 | 2003-01-14 | 小野薬品工業株式会社 | 新規なポリペプチド、その製造方法、そのポリペプチドをコードするdna、そのdnaからなるベクター、そのベクターで形質転換された宿主細胞 |
JP3329109B2 (ja) * | 1994-12-02 | 2002-09-30 | ソニー株式会社 | プラズマアドレス表示装置 |
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US6214540B1 (en) * | 1997-03-26 | 2001-04-10 | University Of Maryland Biotechnology Institute | Chemokines that inhibit immunodeficiency virus infection and methods based thereon |
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CA2245224A1 (en) | 1998-08-14 | 2000-02-14 | Jiang-Hong Giong | Chemokine receptor antagonists and chemotherapeutics |
CA2305787A1 (en) * | 2000-05-09 | 2001-11-09 | The University Of British Columbia | Cxcr4 antagonist treatment of hematopoietic cells |
US20020107195A1 (en) | 1998-07-21 | 2002-08-08 | Smithkline Beecham Corporation | Method for inducing chemotaxis in endothelial cells by administering stromal cell derived factor-1alpha |
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US7378098B2 (en) | 2000-04-12 | 2008-05-27 | The University Of British Columbia | CXC chemokine receptor 4 agonist peptides |
US7368425B2 (en) | 2006-03-24 | 2008-05-06 | Chemokine Therapeutics Corp. | Cyclic peptides for modulating growth of neo-vessels and their use in therapeutic angiogenesis |
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US20040037811A1 (en) | 2002-08-22 | 2004-02-26 | The Cleveland Clinic Foundation | Stromal cell-derived factor-1 mediates stem cell homing and tissue regeneration in ischemic cardiomyopathy |
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US20070060512A1 (en) | 2003-03-04 | 2007-03-15 | Homayoun Sadeghi | Dipeptidyl-peptidase protected protein |
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CN1252089C (zh) * | 2003-09-16 | 2006-04-19 | 广州润兴生物科技有限公司 | 基质细胞衍生因子-1α重组突变体的构建和制备 |
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CA2584553A1 (en) * | 2004-09-17 | 2006-03-23 | Cellgentech, Inc. | External agent for treatment of skin ulcer |
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US20060110374A1 (en) * | 2004-11-24 | 2006-05-25 | Dudy Czeiger | Method to accelerate stem cell recruitment and homing |
JP2008526749A (ja) | 2005-01-04 | 2008-07-24 | ザ ブライハム アンド ウイメンズ ホスピタル, インコーポレイテッド | 自己アセンブリするペプチドナノファイバーを用いたpdgfの徐放性の送達 |
US8153592B2 (en) | 2005-01-10 | 2012-04-10 | Mayo Foundation For Medical Education And Research | Modulating toll-like receptor activity |
KR20100102750A (ko) * | 2005-04-25 | 2010-09-24 | 메사추세츠 인스티튜트 오브 테크놀로지 | 지혈 및 다른 생리학적 활성을 촉진하기 위한 조성물 및 방법 |
UA96926C2 (ru) | 2005-10-31 | 2011-12-26 | Мерк Сероно Са | Применение sdf-1 для лечения и/или профилактики неврологических заболеваний |
WO2007079460A2 (en) | 2006-01-04 | 2007-07-12 | Chemokine Therapeutics Corporation | Design of cxc chemokine analogs for the treatment of human diseases |
US7696309B2 (en) | 2006-10-23 | 2010-04-13 | The Brigham And Women's Hospital, Inc. | Protease resistant mutants of stromal cell derived factor-1 in the repair of tissue damage |
US20080194478A1 (en) * | 2007-02-09 | 2008-08-14 | Gene Signal International Sa | Wound healing agent and composition |
JPWO2010024300A1 (ja) * | 2008-08-26 | 2012-01-26 | 国立大学法人北海道大学 | 骨充填型軟骨組織再生誘導剤 |
CA2763156A1 (en) * | 2009-05-20 | 2010-11-25 | Board Of Regents, The University Of Texas System | Identification of micro-rnas involved in post-myocardial infarction remodeling and heart failure |
-
2007
- 2007-10-19 US US11/976,032 patent/US7696309B2/en active Active
- 2007-10-22 NZ NZ576188A patent/NZ576188A/xx unknown
- 2007-10-22 WO PCT/US2007/022394 patent/WO2008051505A2/en active Application Filing
- 2007-10-22 AU AU2007309479A patent/AU2007309479A1/en not_active Abandoned
- 2007-10-22 CN CN201410353635.XA patent/CN104211800B/zh active Active
- 2007-10-22 EP EP07867257A patent/EP2094288A4/en not_active Withdrawn
- 2007-10-22 CA CA2667280A patent/CA2667280C/en active Active
- 2007-10-22 CN CN200780039382.7A patent/CN101553243B/zh active Active
- 2007-10-22 EP EP13185216.2A patent/EP2676674B1/en active Active
- 2007-10-22 JP JP2009534607A patent/JP5695318B2/ja active Active
-
2009
- 2009-04-06 IL IL198021A patent/IL198021A/en active IP Right Grant
-
2010
- 2010-01-06 US US12/683,253 patent/US7999067B2/en active Active
- 2010-03-23 HK HK10103057.2A patent/HK1136211A1/xx unknown
-
2011
- 2011-07-01 US US13/175,070 patent/US20110269685A1/en not_active Abandoned
-
2013
- 2013-09-27 US US14/039,580 patent/US9631005B2/en active Active
-
2014
- 2014-03-27 IL IL231752A patent/IL231752A0/en unknown
- 2014-10-06 JP JP2014205586A patent/JP2015057058A/ja active Pending
-
2015
- 2015-06-15 HK HK15105619.3A patent/HK1205139A1/xx unknown
-
2016
- 2016-12-09 US US15/374,539 patent/US10774124B2/en active Active
-
2020
- 2020-09-14 US US17/020,237 patent/US20220009984A9/en active Pending
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