HK1204926A1 - Antibodies to matrix metalloproteinase - Google Patents
Antibodies to matrix metalloproteinaseInfo
- Publication number
- HK1204926A1 HK1204926A1 HK15105497.0A HK15105497A HK1204926A1 HK 1204926 A1 HK1204926 A1 HK 1204926A1 HK 15105497 A HK15105497 A HK 15105497A HK 1204926 A1 HK1204926 A1 HK 1204926A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- antibodies
- matrix metalloproteinase
- metalloproteinase
- matrix
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A61K2039/507—Comprising a combination of two or more separate antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Pulmonology (AREA)
- Endocrinology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Communicable Diseases (AREA)
- Rheumatology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Transplantation (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261605181P | 2012-02-29 | 2012-02-29 | |
PCT/US2012/027160 WO2013130078A1 (fr) | 2012-02-29 | 2012-02-29 | Anticorps dirigés contre la métalloprotéinase 9 de la matrice |
US201361755444P | 2013-01-22 | 2013-01-22 | |
PCT/US2013/028456 WO2013130905A1 (fr) | 2012-02-29 | 2013-02-28 | Anticorps dirigés contre la métalloprotéinase 9 de matrice |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1204926A1 true HK1204926A1 (en) | 2015-12-11 |
Family
ID=49003113
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK15105497.0A HK1204926A1 (en) | 2012-02-29 | 2015-06-10 | Antibodies to matrix metalloproteinase |
HK18103980.6A HK1244671A1 (zh) | 2012-02-29 | 2015-06-10 | 抗基質金屬蛋白酶9的抗體 |
HK18107631.0A HK1248246A1 (zh) | 2012-02-29 | 2015-06-19 | 抗基質金屬蛋白酶9的抗體 |
HK15105850.1A HK1204981A1 (en) | 2012-02-29 | 2015-06-19 | Antibodies to matrix metalloproteinase |
Family Applications After (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK18103980.6A HK1244671A1 (zh) | 2012-02-29 | 2015-06-10 | 抗基質金屬蛋白酶9的抗體 |
HK18107631.0A HK1248246A1 (zh) | 2012-02-29 | 2015-06-19 | 抗基質金屬蛋白酶9的抗體 |
HK15105850.1A HK1204981A1 (en) | 2012-02-29 | 2015-06-19 | Antibodies to matrix metalloproteinase |
Country Status (23)
Country | Link |
---|---|
US (2) | US9732156B2 (fr) |
EP (2) | EP3255063A3 (fr) |
JP (3) | JP6144286B2 (fr) |
KR (1) | KR20140130513A (fr) |
CN (2) | CN104271156B (fr) |
AP (1) | AP2014007921A0 (fr) |
AU (1) | AU2013203619B2 (fr) |
BR (1) | BR112014021081A2 (fr) |
CA (1) | CA2865501A1 (fr) |
CL (1) | CL2014002258A1 (fr) |
CO (1) | CO7061039A2 (fr) |
CR (1) | CR20140451A (fr) |
EA (1) | EA201491599A1 (fr) |
EC (1) | ECSP14020644A (fr) |
HK (4) | HK1204926A1 (fr) |
MD (1) | MD20140108A2 (fr) |
MX (2) | MX2014010447A (fr) |
MY (1) | MY167236A (fr) |
NZ (1) | NZ629178A (fr) |
PH (1) | PH12014501927A1 (fr) |
SG (2) | SG11201405273YA (fr) |
WO (1) | WO2013130905A1 (fr) |
ZA (1) | ZA201406318B (fr) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5878538B2 (ja) | 2010-08-27 | 2016-03-08 | ギリアド バイオロジクス, インク.Gilead Biologics, Inc. | マトリクスメタロプロティナーゼ9に対する抗体 |
CA2839792A1 (fr) | 2011-05-10 | 2012-11-15 | Nestec S.A. | Methodes de profilage de l'activite d'une maladie pour une prise en charge therapeutique personnalisee |
US9732156B2 (en) | 2012-02-29 | 2017-08-15 | Gilead Biologics, Inc. | Methods of treating rheumatoid arthritis using antibodies to matrix metalloproteinase 9 |
BR112014021477A2 (pt) | 2012-02-29 | 2018-06-12 | Gilead Sciences Inc | anticorpos para metaloproteinase de matriz 9 |
KR102332302B1 (ko) * | 2013-09-13 | 2021-12-01 | 제넨테크, 인크. | 세포주에서 숙주 세포 단백질 및 재조합 폴리펩티드 생성물을 검출 및 정량화하기 위한 조성물 및 방법 |
EP3683232A1 (fr) | 2013-09-13 | 2020-07-22 | F. Hoffmann-La Roche AG | Procédés et compositions comprenant des polypeptides recombinants purifiés |
WO2015116820A1 (fr) * | 2014-01-30 | 2015-08-06 | Coherus Biosciences, Inc. | Milieux de perfusion |
EA201691414A1 (ru) * | 2014-02-27 | 2017-03-31 | Джилид Сайэнс, Инк. | Антитела к матриксной металлопротеиназе 9 и способы их применения |
EP2985296A1 (fr) * | 2014-08-13 | 2016-02-17 | Calypso Biotech SA | Anticorps spécifiques de MMP9 |
UA122395C2 (uk) | 2014-08-19 | 2020-11-10 | Мерк Шарп Енд Доум Корп. | Антитіло проти tigit |
JP6976241B2 (ja) | 2015-08-14 | 2021-12-08 | メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. | 抗tigit抗体 |
WO2017106566A1 (fr) * | 2015-12-17 | 2017-06-22 | Gilead Sciences, Inc. | Combinaison d'un inhibiteur des jak et d'une protéine fixant mmp9 pour traiter des troubles inflammatoires |
KR101783907B1 (ko) * | 2016-03-15 | 2017-10-10 | 다이노나(주) | CD66c에 대한 항체와 화학치료제를 포함하는 폐암 예방 또는 치료용 약학조성물 |
EP3440113A1 (fr) * | 2016-04-08 | 2019-02-13 | Gilead Sciences, Inc. | Compositions et méthodes de traitement du cancer, de maladies inflammatoires et de maladies autoimmunes |
TWI676482B (zh) * | 2017-03-23 | 2019-11-11 | 高雄醫學大學 | 盤基蛋白結構域受體1的抑制劑及活化劑及其用途 |
WO2018220588A1 (fr) | 2017-05-31 | 2018-12-06 | Nestec S.A. | Procédés d'évaluation de la cicatrisation des muqueuses chez des patients atteints de la maladie de crohn |
CN111051339A (zh) | 2017-07-18 | 2020-04-21 | 第一三共株式会社 | 活性mmp-9-结合肽 |
WO2019094608A1 (fr) | 2017-11-08 | 2019-05-16 | Denali Therapeutics Inc. | Anticorps anti-bace1 et leurs procédés d'utilisation |
US20210332145A1 (en) * | 2018-10-09 | 2021-10-28 | Single Cell Technology, Inc. | Anti-bcma antibodies |
IL264768A (en) * | 2019-02-10 | 2020-08-31 | Sagi Irit | ANTI-MATRIX METALLOPROTEINASE 7 (MMP-7) inhibitory antibody and its use |
US11332546B2 (en) | 2019-05-21 | 2022-05-17 | The Regents Of The University Of California | Protease inhibitory antibodies and methods of use thereof |
US20230074615A1 (en) * | 2019-05-21 | 2023-03-09 | The Regents Of The University Of California | Mmp-9 antibodies and methods of use thereof |
WO2021202592A2 (fr) * | 2020-03-30 | 2021-10-07 | Oregon Health & Science University | Anticorps monoclonaux pour l'administration intracellulaire de charges utiles |
WO2023154814A2 (fr) * | 2022-02-09 | 2023-08-17 | Sera Prognostics, Inc. | Anticorps anti-shbg et anti-ibp4 et leurs procédés d'utilisation |
CN114292834B (zh) * | 2022-03-09 | 2022-05-31 | 天津辅元生物医药科技有限公司 | 一种融合蛋白酶及其制备方法、其在提取i型胶原蛋白中的应用以及该i型胶原蛋白的用途 |
Family Cites Families (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
DE3920358A1 (de) | 1989-06-22 | 1991-01-17 | Behringwerke Ag | Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung |
US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
US5661016A (en) | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
US5633425A (en) | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
WO1992003918A1 (fr) | 1990-08-29 | 1992-03-19 | Genpharm International, Inc. | Animaux non humains transgeniques capables de produire des anticorps heterologues |
GB9022788D0 (en) | 1990-10-19 | 1990-12-05 | Cortecs Ltd | Pharmaceutical formulations |
DK1136556T3 (da) | 1991-11-25 | 2005-10-03 | Enzon Inc | Fremgangsmåde til fremstilling af multivalente antigen-bindende proteiner |
WO1995015374A1 (fr) | 1993-11-30 | 1995-06-08 | Fuji Yakuhin Kogyo Kabushiki Kaisha | Nouvelle metalloprotease et adn codant pour cette derniere |
US5612030A (en) | 1995-01-17 | 1997-03-18 | University Of Kentucky Research Foundation | Anti-idiotype monoclonal antibody 1A7 and use for the treatment of melanoma and small cell carcinoma |
CA2329940A1 (fr) | 1998-06-05 | 1999-12-09 | Mayo Foundation For Medical Education And Research | Traitement du myelome multiple au moyen d'anticorps du cd38 obtenus par genie genetique |
US7101975B1 (en) | 1999-07-13 | 2006-09-05 | University Of Southern California | Method and composition for inhibition of angiogenesis using antagonists based on MMP-9 and β1 integrins |
CN1379685A (zh) | 1999-07-13 | 2002-11-13 | 南加利福尼亚大学 | 用基于MMP-9和β1整联蛋白的拮抗剂抑制血管发生的新方法和组合物 |
AU2002235692A1 (en) | 2001-02-23 | 2002-09-04 | Biophage Inc. | Methods and compositions for preventing and treating neutrophil-mediated diseases |
SE0102298D0 (sv) | 2001-06-27 | 2001-06-27 | Astrazeneca Ab | Crystal structure of enzyme and uses thereof |
WO2003006006A1 (fr) | 2001-07-09 | 2003-01-23 | The Regents Of The University Of California | Utilisation d'inhibiteurs de metalloproteinases matricielles pour limiter les atteintes nerveuses |
AU2002352089A1 (en) | 2001-11-23 | 2003-06-10 | Universite Catholique De Louvain | Medical use of antibodies directed against human matrix metalloproteinases or related tissue proteinases for the treatment of abnormal uterine bleeding and endometriosis |
US20040115194A1 (en) | 2002-09-06 | 2004-06-17 | Yi Wang | Method of treatment of asthma using antibodies to complement component C5 |
WO2004076614A2 (fr) | 2003-02-27 | 2004-09-10 | Bernd Hinzmann | Sequences d'acide nucleique humaines issues de carcinomes de la prostate |
ATE517926T1 (de) | 2003-04-04 | 2011-08-15 | Yeda Res & Dev | Antikörper zur hemmung der aktivität von mmp-2 und mmp-9 |
CA2550551C (fr) * | 2004-01-16 | 2013-10-29 | Regeneron Pharmaceuticals, Inc. | Polypeptides hybrides capables d'activer des recepteurs |
WO2006037513A1 (fr) | 2004-10-09 | 2006-04-13 | Bayer Healthcare Ag | Agents diagnostiques et agents therapeutiques utilises dans le cadre de maladies associees a la metalloproteinase 9 matricielle (mmp9) |
WO2007005426A2 (fr) | 2005-06-29 | 2007-01-11 | Rules-Based Medicine, Inc. | Methodes et trousses pour le diagnostic du syndrome coronaire aigu |
CN101370832B (zh) * | 2005-12-02 | 2014-07-02 | 健泰科生物技术公司 | 结合多肽及其用途 |
US8957187B2 (en) | 2005-12-02 | 2015-02-17 | Genentech, Inc. | Binding polypeptides and uses thereof |
WO2007144781A2 (fr) | 2006-04-21 | 2007-12-21 | Diagnotech Pty. Ltd. | Procédés de diagnostic et trousses utilisant des anticorps dirigés contre des métalloprotéases |
WO2008088864A2 (fr) | 2007-01-18 | 2008-07-24 | The Trustess Of Columbia University In The City Of New York | Procédés associés à une métalloprotéinase-9 matricielle |
JP5513130B2 (ja) | 2007-02-23 | 2014-06-04 | イェダ リサーチ アンド デベロップメント カンパニー リミテッド | 金属タンパク質の活性を阻害するために有用な抗体および該抗体を含有する医薬組成物 |
WO2008154439A1 (fr) * | 2007-06-08 | 2008-12-18 | Irm Llc | Procédés et compositions pour induire une apoptose dans des cellules cancéreuses |
HUE025283T2 (en) | 2007-08-02 | 2016-03-29 | Gilead Biologics Inc | LOX and LOX2 inhibitors and their use |
KR20100071972A (ko) | 2007-08-15 | 2010-06-29 | 예다 리서치 앤드 디벨럽먼트 캄파니 리미티드 | Mmp-9의 조절인자 및 그의 용도 |
AU2008338421A1 (en) | 2007-12-17 | 2009-06-25 | Dyax Corp. | Compositions and methods for treating osteolytic disorders comprising MMP-14 binding proteins |
EP2262529A4 (fr) * | 2008-03-03 | 2013-05-08 | Dyax Corp | Protéines de liaison à la métalloprotéinase 9 |
JP2011517320A (ja) | 2008-03-03 | 2011-06-02 | ダイアックス コーポレーション | メタロプロテアーゼ9結合タンパク質およびメタロプロテアーゼ2結合タンパク質 |
US20100098659A1 (en) * | 2008-10-22 | 2010-04-22 | Revalesio Corporation | Compositions and methods for treating matrix metalloproteinase 9 (mmp9)-mediated conditions |
CA2741492A1 (fr) | 2008-10-22 | 2010-04-29 | Dyax Corp. | Polytherapie comportant des proteines de liaison de protease pour des troubles inflammatoires |
US20110286916A1 (en) * | 2008-11-20 | 2011-11-24 | Jose Miguel Aste-Amezaga | Generation and characterization of anti-notch antibodies for therapeutic and diagnostic use |
DE102009030321A1 (de) * | 2009-06-24 | 2011-01-05 | Siemens Aktiengesellschaft | Verfahren zur Abbildung von Tumorgewebe |
AU2011210362B2 (en) | 2010-01-27 | 2015-09-10 | Yeda Research And Development Co. Ltd. | Antibodies that inhibit metalloproteins |
AU2011212830B2 (en) | 2010-02-04 | 2014-05-22 | Gilead Biologics, Inc. | Antibodies that bind to lysyl oxidase-like 2 (LOXL2) and methods of use therefor |
US8896483B2 (en) * | 2010-07-15 | 2014-11-25 | Evgeny Markin | Method of automatic target angle tracking by monopulse radar under conditions of interference distorting location characteristic |
JP5878538B2 (ja) | 2010-08-27 | 2016-03-08 | ギリアド バイオロジクス, インク.Gilead Biologics, Inc. | マトリクスメタロプロティナーゼ9に対する抗体 |
US8003110B1 (en) * | 2011-01-24 | 2011-08-23 | Matthias W. Rath | Metalloproteinase oligopeptides and their therapeutic use |
US9732156B2 (en) | 2012-02-29 | 2017-08-15 | Gilead Biologics, Inc. | Methods of treating rheumatoid arthritis using antibodies to matrix metalloproteinase 9 |
BR112014021477A2 (pt) * | 2012-02-29 | 2018-06-12 | Gilead Sciences Inc | anticorpos para metaloproteinase de matriz 9 |
-
2013
- 2013-02-28 US US13/781,662 patent/US9732156B2/en active Active
- 2013-02-28 CA CA2865501A patent/CA2865501A1/fr not_active Abandoned
- 2013-02-28 CN CN201380022489.6A patent/CN104271156B/zh active Active
- 2013-02-28 WO PCT/US2013/028456 patent/WO2013130905A1/fr active Application Filing
- 2013-02-28 JP JP2014560065A patent/JP6144286B2/ja active Active
- 2013-02-28 KR KR1020147026830A patent/KR20140130513A/ko active IP Right Grant
- 2013-02-28 NZ NZ629178A patent/NZ629178A/en not_active IP Right Cessation
- 2013-02-28 MX MX2014010447A patent/MX2014010447A/es unknown
- 2013-02-28 AU AU2013203619A patent/AU2013203619B2/en active Active
- 2013-02-28 BR BR112014021081A patent/BR112014021081A2/pt not_active IP Right Cessation
- 2013-02-28 SG SG11201405273YA patent/SG11201405273YA/en unknown
- 2013-02-28 SG SG10201610788VA patent/SG10201610788VA/en unknown
- 2013-02-28 EP EP17168528.2A patent/EP3255063A3/fr not_active Withdrawn
- 2013-02-28 MY MYPI2014002488A patent/MY167236A/en unknown
- 2013-02-28 EP EP13754254.4A patent/EP2819697A4/fr not_active Withdrawn
- 2013-02-28 EA EA201491599A patent/EA201491599A1/ru unknown
- 2013-02-28 AP AP2014007921A patent/AP2014007921A0/xx unknown
- 2013-02-28 MD MDA20140108A patent/MD20140108A2/ro not_active Application Discontinuation
- 2013-02-28 CN CN201710291984.7A patent/CN107184974A/zh active Pending
-
2014
- 2014-08-26 CL CL2014002258A patent/CL2014002258A1/es unknown
- 2014-08-27 PH PH12014501927A patent/PH12014501927A1/en unknown
- 2014-08-27 ZA ZA2014/06318A patent/ZA201406318B/en unknown
- 2014-08-29 MX MX2018007630A patent/MX2018007630A/es unknown
- 2014-08-29 CO CO14190938A patent/CO7061039A2/es unknown
- 2014-09-25 CR CR20140451A patent/CR20140451A/es unknown
- 2014-09-29 EC ECIEPI201420644A patent/ECSP14020644A/es unknown
-
2015
- 2015-06-10 HK HK15105497.0A patent/HK1204926A1/xx unknown
- 2015-06-10 HK HK18103980.6A patent/HK1244671A1/zh unknown
- 2015-06-19 HK HK18107631.0A patent/HK1248246A1/zh unknown
- 2015-06-19 HK HK15105850.1A patent/HK1204981A1/xx unknown
-
2017
- 2017-05-10 JP JP2017093971A patent/JP6343368B2/ja active Active
- 2017-07-07 US US15/644,405 patent/US20180002446A1/en not_active Abandoned
-
2018
- 2018-05-17 JP JP2018095361A patent/JP2018150343A/ja active Pending
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL289241A (en) | Antibodies to tau | |
HK1204981A1 (en) | Antibodies to matrix metalloproteinase | |
IL255300A0 (en) | Antibodies to matrix metalloproteinase 9 (mmp9) | |
HK1208036A1 (en) | Antibodies to matrix metalloproteinase | |
EP2878852A4 (fr) | Amortisseur hydraulique | |
EP2844290A4 (fr) | Nouveaux anticorps | |
EP2832855A4 (fr) | Nouvel anticorps anti-siglec-15 | |
GB201303603D0 (en) | Improvements relating to valves | |
EP2804876A4 (fr) | Nouveaux anticorps | |
EP2863742A4 (fr) | Microcapsule | |
GB2507762B (en) | Improvements to dartboards | |
SG10201700568RA (en) | Antibodies to matrix metalloproteinase 9 | |
GB201209623D0 (en) | Improvements relating to mobile technology | |
GB201208097D0 (en) | Improvements relating to mobile technology | |
UA22128S (uk) | Причеп до мотоблоку | |
GB201209584D0 (en) | Modified antibodies |