HK1204549A1 - 預防再激活的結核病 疫苗 - Google Patents
預防再激活的結核病 疫苗Info
- Publication number
- HK1204549A1 HK1204549A1 HK15103708.0A HK15103708A HK1204549A1 HK 1204549 A1 HK1204549 A1 HK 1204549A1 HK 15103708 A HK15103708 A HK 15103708A HK 1204549 A1 HK1204549 A1 HK 1204549A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- tuberculosis
- vaccine
- prevent reactivation
- reactivation
- prevent
- Prior art date
Links
- 230000007420 reactivation Effects 0.000 title 1
- 201000008827 tuberculosis Diseases 0.000 title 1
- 229960005486 vaccine Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/14—Peptides, e.g. proteins
- A61K49/16—Antibodies; Immunoglobulins; Fragments thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200900539 | 2009-04-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1204549A1 true HK1204549A1 (zh) | 2015-11-27 |
Family
ID=43010694
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK12106837.0A HK1166018A1 (zh) | 2009-04-24 | 2012-07-11 | 預防再激活的結核病 疫苗 |
| HK15103708.0A HK1204549A1 (zh) | 2009-04-24 | 2012-07-11 | 預防再激活的結核病 疫苗 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK12106837.0A HK1166018A1 (zh) | 2009-04-24 | 2012-07-11 | 預防再激活的結核病 疫苗 |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US9074001B2 (zh) |
| EP (1) | EP2421557B1 (zh) |
| JP (2) | JP5839361B2 (zh) |
| KR (2) | KR20120014176A (zh) |
| CN (2) | CN104107425B (zh) |
| AU (1) | AU2010238943B9 (zh) |
| BR (1) | BRPI1006452A2 (zh) |
| CA (1) | CA2759583C (zh) |
| DK (1) | DK2421557T3 (zh) |
| ES (1) | ES2714383T3 (zh) |
| HK (2) | HK1166018A1 (zh) |
| IL (1) | IL215591A (zh) |
| MX (2) | MX2011011186A (zh) |
| PL (1) | PL2421557T3 (zh) |
| TR (1) | TR201903223T4 (zh) |
| WO (1) | WO2010121618A1 (zh) |
| ZA (1) | ZA201108564B (zh) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1877426B1 (en) | 2005-04-29 | 2012-02-01 | GlaxoSmithKline Biologicals SA | Method for preventing or treating m tuberculosis infection |
| GB0618127D0 (en) * | 2006-09-14 | 2006-10-25 | Isis Innovation | Biomarker |
| AU2009273132B2 (en) | 2008-07-25 | 2015-09-03 | Glaxo Group Limited | The tuberculosis Rv2386c protein, compositions and uses thereof |
| KR20110060891A (ko) | 2008-07-25 | 2011-06-08 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 신규한 조성물 및 방법 |
| ES2602430T3 (es) * | 2008-07-25 | 2017-02-21 | Glaxosmithkline Biologicals S.A. | Polipéptidos, polinucleótidos y composiciones para uso en el tratamiento de tuberculosis latente |
| GB0906215D0 (en) | 2009-04-09 | 2009-05-20 | Lalvani Ajit | Diagnostic test |
| JP6010463B2 (ja) | 2010-01-27 | 2016-10-19 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | 改変された結核抗原 |
| LT2661253T (lt) * | 2011-01-04 | 2017-05-25 | Archivel Farma, Sl | Liposomų kompozicija, tinkama tuberkuliozės gydymui arba prevencijai |
| RU2602771C2 (ru) | 2012-01-12 | 2016-11-20 | Арчивель Фарма, С.Л. | Вакцина мбтк против астмы |
| EP2912056B1 (en) | 2012-10-23 | 2020-02-12 | Statens Serum Institut | M. tuberculosis vaccines |
| CN110075287A (zh) | 2013-03-15 | 2019-08-02 | 宾夕法尼亚大学理事会 | 用于结核病的预防或治疗的合成免疫原 |
| CA2933817C (en) * | 2013-12-16 | 2023-04-04 | Statens Serum Institut | Diagnostic reagents for improved in vivo or in vitro cell-mediated immunological diagnosis of tuberculosis |
| JP6605480B2 (ja) * | 2014-01-09 | 2019-11-13 | トランスジェン・ソシエテ・アノニム | ヘテロオリゴマーマイコバクテリア抗原の融合物 |
| US10004793B2 (en) | 2014-04-24 | 2018-06-26 | Statens Serum Institut | M.tuberculosis vaccines |
| CN104151433A (zh) * | 2014-08-11 | 2014-11-19 | 兰州大学 | 一种结核分枝杆菌融合蛋白及其制备方法和应用 |
| CN104225591A (zh) * | 2014-09-15 | 2014-12-24 | 兰州大学 | 一种免疫佐剂及含有该免疫佐剂的疫苗 |
| EP3458088A2 (en) * | 2016-05-21 | 2019-03-27 | Infectious Disease Research Institute | Compositions and methods for treating secondary tuberculosis and nontuberculous mycobacterium infections |
| US20210290747A1 (en) * | 2018-04-26 | 2021-09-23 | Children's National Medical Center | Mycobacterial antigen compositions and methods of use |
| CN110423279B (zh) * | 2019-06-20 | 2021-07-27 | 扩增生物科技(北京)有限公司 | 结核分枝杆菌重组融合蛋白eecc及其制备方法和应用 |
| KR102577332B1 (ko) * | 2021-12-29 | 2023-09-11 | 재단법인 오송첨단의료산업진흥재단 | 항원성 및 안정성이 개선된 항원을 포함하는 잠복결핵 진단용 조성물 |
| CN117777259A (zh) * | 2024-02-23 | 2024-03-29 | 上海科新生物技术股份有限公司 | 检测结核感染的抗原组合物、试剂盒及其应用 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4599231A (en) | 1984-03-09 | 1986-07-08 | Scripps Clinic And Research Foundation | Synthetic hepatitis B virus vaccine including both T cell and B cell determinants |
| US4599230A (en) | 1984-03-09 | 1986-07-08 | Scripps Clinic And Research Foundation | Synthetic hepatitis B virus vaccine including both T cell and B cell determinants |
| US4608251A (en) | 1984-11-09 | 1986-08-26 | Pitman-Moore, Inc. | LHRH analogues useful in stimulating anti-LHRH antibodies and vaccines containing such analogues |
| US4601903A (en) | 1985-05-01 | 1986-07-22 | The United States Of America As Represented By The Department Of Health And Human Services | Vaccine against Neisseria meningitidis Group B serotype 2 invasive disease |
| US5955077A (en) * | 1993-07-02 | 1999-09-21 | Statens Seruminstitut | Tuberculosis vaccine |
| US6641814B1 (en) * | 1997-04-02 | 2003-11-04 | Statens Serum Institut | Nucleic acids fragments and polypeptide fragments derived from M. tuberculosis |
| CN1105236A (zh) * | 1993-11-13 | 1995-07-19 | 丛繁滋 | 肺结核防传播及治疗用气雾剂及其制备方法 |
| CN1051234C (zh) * | 1994-04-15 | 2000-04-12 | 焦安国 | 一种治疗结核病的药物 |
| EP1741718A3 (en) | 1995-06-07 | 2007-03-28 | Sanofi Pasteur Inc. | Expression of lipoproteins |
| US6338852B1 (en) * | 1995-09-01 | 2002-01-15 | Corixa Corporation | Compounds and methods for diagnosis of tuberculosis |
| US6982085B2 (en) * | 1997-04-02 | 2006-01-03 | Statens Serum Institut | TB diagnostic based on antigens from M. tuberculosis |
| AU779495B2 (en) | 1999-07-13 | 2005-01-27 | Statens Serum Institut | Tuberculosis vaccine and diagnostics based on the mycobacterium tuberculosis esat-6 gene family |
| WO2001079274A2 (en) | 2000-04-19 | 2001-10-25 | Statens Serum Institut | Tuberculosis antigens and methods of use thereof |
| GB0030368D0 (en) | 2000-12-13 | 2001-01-24 | Inst Of Molecul & Cell Biology | Dormancy-induced mycobacterium proteins |
| CZ20031866A3 (cs) * | 2001-01-08 | 2004-03-17 | Isis Innovation Limited | Způsob pro stanovení účinnosti léčení mykobakteriální infekce |
| EP1350839B1 (en) | 2002-04-05 | 2010-06-02 | Institut Pasteur | Identification of virulence associated regions RD1 and RD5 enabling the development of improved vaccines of M. bovis BCG and M. microti |
| WO2004006952A2 (en) | 2002-07-13 | 2004-01-22 | Statens Serum Institut | Therapeutic tuberculosis vaccines |
| WO2004067718A2 (en) | 2003-01-24 | 2004-08-12 | Emory University | Necrosis-deficient mutants of tuberculosis bacteria |
| EP1781313A4 (en) * | 2004-06-17 | 2009-08-26 | Beckman Coulter Inc | MYCOBACTERIUM TUBERCULOSIS EPITOPES AND METHODS OF USE |
| NZ555907A (en) * | 2004-11-16 | 2009-12-24 | Aeras Global Tb Vaccine Found | Multivalent vaccines comprising recombinant viral vectors |
| NZ560468A (en) | 2005-01-05 | 2010-05-28 | Isis Innovation | Compositions for immunizing against mycobacterium using Ag85A |
| EP1877426B1 (en) | 2005-04-29 | 2012-02-01 | GlaxoSmithKline Biologicals SA | Method for preventing or treating m tuberculosis infection |
| JP5219808B2 (ja) | 2005-06-23 | 2013-06-26 | ステイテンス・セラム・インスティテュート | 改良された結核ワクチン |
| WO2008000261A2 (en) * | 2006-06-28 | 2008-01-03 | Statens Serum Institut | Expanding the t cell repertoire to include subdominant epitopes by vaccination with antigens delivered as protein fragments or peptide cocktails |
| ES2602430T3 (es) | 2008-07-25 | 2017-02-21 | Glaxosmithkline Biologicals S.A. | Polipéptidos, polinucleótidos y composiciones para uso en el tratamiento de tuberculosis latente |
-
2010
- 2010-04-23 US US13/262,914 patent/US9074001B2/en active Active
- 2010-04-23 BR BRPI1006452A patent/BRPI1006452A2/pt not_active Application Discontinuation
- 2010-04-23 CN CN201410141208.5A patent/CN104107425B/zh active Active
- 2010-04-23 TR TR2019/03223T patent/TR201903223T4/tr unknown
- 2010-04-23 CA CA2759583A patent/CA2759583C/en active Active
- 2010-04-23 KR KR1020117028104A patent/KR20120014176A/ko active Search and Examination
- 2010-04-23 ES ES10766664T patent/ES2714383T3/es active Active
- 2010-04-23 CN CN201080017717.7A patent/CN102413837B/zh active Active
- 2010-04-23 PL PL10766664T patent/PL2421557T3/pl unknown
- 2010-04-23 WO PCT/DK2010/000054 patent/WO2010121618A1/en active Application Filing
- 2010-04-23 KR KR1020177016378A patent/KR20170072366A/ko active Search and Examination
- 2010-04-23 MX MX2011011186A patent/MX2011011186A/es active IP Right Grant
- 2010-04-23 MX MX2015009347A patent/MX370744B/es unknown
- 2010-04-23 AU AU2010238943A patent/AU2010238943B9/en active Active
- 2010-04-23 JP JP2012506340A patent/JP5839361B2/ja active Active
- 2010-04-23 EP EP10766664.6A patent/EP2421557B1/en active Active
- 2010-04-23 DK DK10766664.6T patent/DK2421557T3/en active
-
2011
- 2011-10-06 IL IL215591A patent/IL215591A/en active IP Right Grant
- 2011-11-22 ZA ZA2011/08564A patent/ZA201108564B/en unknown
-
2012
- 2012-07-11 HK HK12106837.0A patent/HK1166018A1/zh unknown
- 2012-07-11 HK HK15103708.0A patent/HK1204549A1/zh unknown
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2014
- 2014-12-12 US US14/569,341 patent/US10519202B2/en active Active
-
2015
- 2015-06-24 JP JP2015127000A patent/JP6215260B2/ja active Active
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