HK1202333A1 - Combination of kinase inhibitors and uses thereof - Google Patents
Combination of kinase inhibitors and uses thereofInfo
- Publication number
- HK1202333A1 HK1202333A1 HK15102758.1A HK15102758A HK1202333A1 HK 1202333 A1 HK1202333 A1 HK 1202333A1 HK 15102758 A HK15102758 A HK 15102758A HK 1202333 A1 HK1202333 A1 HK 1202333A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- combination
- kinase inhibitors
- kinase
- inhibitors
- Prior art date
Links
- 229940043355 kinase inhibitor Drugs 0.000 title 1
- 239000003757 phosphotransferase inhibitor Substances 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
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- A—HUMAN NECESSITIES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/423—Oxazoles condensed with carbocyclic rings
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- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
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- A—HUMAN NECESSITIES
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Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161558928P | 2011-11-11 | 2011-11-11 | |
PCT/US2012/064719 WO2013071264A1 (en) | 2011-11-11 | 2012-11-12 | Combination of kinase inhibitors and uses thereof |
Publications (1)
Publication Number | Publication Date |
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HK1202333A1 true HK1202333A1 (en) | 2015-09-25 |
Family
ID=48290670
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK15102758.1A HK1202333A1 (en) | 2011-11-11 | 2015-03-17 | Combination of kinase inhibitors and uses thereof |
Country Status (7)
Country | Link |
---|---|
US (1) | US9682141B2 (xx) |
EP (1) | EP2776837A4 (xx) |
JP (1) | JP6126615B2 (xx) |
CN (1) | CN104204804B (xx) |
CA (1) | CA2855666A1 (xx) |
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Families Citing this family (24)
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JP6434416B2 (ja) | 2012-11-08 | 2018-12-05 | ライゼン・ファーマシューティカルズ・エスアー | PDE4阻害剤とPI3δ阻害剤または二重PI3δ−γキナーゼ阻害剤とを含有する薬学的組成物 |
CN104177346A (zh) * | 2013-05-21 | 2014-12-03 | 苏州科捷生物医药有限公司 | 喹唑啉类化合物及其用途 |
EP3110801B1 (en) * | 2014-02-27 | 2019-01-30 | Council Of Scientific & Industrial Research | 6-aryl-4-phenylamino-quinazoline analogs as phosphoinositide-3-kinase inhibitors |
CN103864800A (zh) * | 2014-04-03 | 2014-06-18 | 定陶县友帮化工有限公司 | 6-氯咪唑并[1,2-b]哒嗪的合成方法 |
JP6377400B2 (ja) * | 2014-05-08 | 2018-08-22 | 株式会社小糸製作所 | 車両用灯具 |
WO2016004272A1 (en) | 2014-07-02 | 2016-01-07 | Pharmacyclics Llc | Inhibitors of bruton's tyrosine kinase |
US20160317438A1 (en) * | 2015-04-29 | 2016-11-03 | Psivida Us, Inc. | Injectable sustained release intraocular device |
US20160324836A1 (en) * | 2015-05-05 | 2016-11-10 | pSivida US.Inc. | Injectable depot formulations |
US10774068B2 (en) | 2015-06-25 | 2020-09-15 | The Scripps Research Institute | Composition and methods for inhibiting mammalian sterile 20-like kinase 1 |
CN105085503A (zh) * | 2015-09-20 | 2015-11-25 | 徐敬媛 | 一种治疗呼吸道感染的药物组合物 |
US11352328B2 (en) | 2016-07-12 | 2022-06-07 | Arisan Therapeutics Inc. | Heterocyclic compounds for the treatment of arenavirus |
CN106483293A (zh) * | 2016-10-13 | 2017-03-08 | 广州华弘生物科技有限公司 | He4a 临床免疫检测试剂盒及其制备方法 |
CN106632351A (zh) * | 2016-11-18 | 2017-05-10 | 山东友帮生化科技有限公司 | 6‑溴咪唑并[1,2‑a]吡嗪‑3‑羧酸乙酯的制法 |
EP3348144A3 (en) * | 2017-01-17 | 2018-10-03 | OxiScience LLC | Composition for the prevention and elimination of odors |
US11337965B2 (en) | 2017-08-25 | 2022-05-24 | Memorial Sloan Kettering Cancer Center | Kinase mutation-associated neurodegenerative disorders |
MX2020014116A (es) * | 2018-06-27 | 2021-06-15 | Reborna Biosciences Inc | Agente profilactico o terapeutico para atrofia muscular espinal. |
MX2021005875A (es) * | 2018-11-20 | 2021-09-23 | Univ Georgetown | Composiciones y métodos para el tratamiento de trastornos neurodegenerativos, miodegenerativos y de almacenamiento lisosómico. |
WO2020219963A1 (en) * | 2019-04-26 | 2020-10-29 | University Of Houston System | Methods and compositions for treating chronic inflammatory injury, metaplasia, dysplasia and cancers of epithelial tissues |
CN110051859B (zh) * | 2019-06-06 | 2020-06-12 | 鲁南制药集团股份有限公司 | 一种阿昔替尼环糊精包合物 |
CN111187181B (zh) * | 2019-11-22 | 2023-05-05 | 吉林大学 | 一种2-(4-氨基苯基)-2-甲基丙腈化合物的制备方法 |
US11857551B1 (en) | 2020-07-10 | 2024-01-02 | Ting Therapeutics Llc | Methods for the prevention and treatment of hearing loss |
TW202337433A (zh) * | 2022-02-08 | 2023-10-01 | 美商德洛斯股份有限公司 | 用於治療癌症及其他適應症之組成物及方法 |
WO2024008799A1 (en) * | 2022-07-06 | 2024-01-11 | Institut National de la Santé et de la Recherche Médicale | Methods for the treatment of proliferative glomerulonephritis |
CN116425743A (zh) * | 2022-12-30 | 2023-07-14 | 贵州医科大学 | 一种作为PI3Kα激酶抑制剂的苯并杂环类化合物及其制备方法与应用 |
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EP1871345B1 (en) | 2005-04-12 | 2012-08-01 | Elan Pharma International Limited | Nanoparticulate erlotinib formulations |
AR060632A1 (es) * | 2006-04-26 | 2008-07-02 | Genentech Inc | Compuestos inhibidores de fosfoinositida 3- quinasa y metodos de uso |
WO2008124161A1 (en) * | 2007-04-10 | 2008-10-16 | Exelixis, Inc. | Methods of treating cancer using pyridopyrimidinone inhibitors of pi3k alpha |
TWI471134B (zh) * | 2007-09-12 | 2015-02-01 | Genentech Inc | 肌醇磷脂3-激酶抑制劑化合物及化療劑之組合及使用方法 |
WO2010008847A2 (en) * | 2008-06-24 | 2010-01-21 | Takeda Pharmaceutical Company Limited | Pi3k/m tor inhibitors |
IN2012DN01961A (xx) | 2009-08-17 | 2015-08-21 | Intellikine Llc | |
WO2011031861A1 (en) | 2009-09-09 | 2011-03-17 | Quintiles Transnational Corp. | Methods for predicting responsiveness of a disease or disorder to a receptor tyrosine kinase inhibitor by analysis of mutations in pik3ca |
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JP2014533284A (ja) | 2014-12-11 |
EP2776837A1 (en) | 2014-09-17 |
CN104204804B (zh) | 2016-09-28 |
US9682141B2 (en) | 2017-06-20 |
JP6126615B2 (ja) | 2017-05-10 |
EP2776837A4 (en) | 2015-05-20 |
CN104204804A (zh) | 2014-12-10 |
CA2855666A1 (en) | 2013-05-16 |
WO2013071264A1 (en) | 2013-05-16 |
US20150030588A1 (en) | 2015-01-29 |
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