HK1201844A1 - 端經修飾的葡萄糖依賴性促胰島素多肽 的類似物 - Google Patents
端經修飾的葡萄糖依賴性促胰島素多肽 的類似物Info
- Publication number
- HK1201844A1 HK1201844A1 HK15101504.0A HK15101504A HK1201844A1 HK 1201844 A1 HK1201844 A1 HK 1201844A1 HK 15101504 A HK15101504 A HK 15101504A HK 1201844 A1 HK1201844 A1 HK 1201844A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- gip
- analogues
- glucose
- modified
- terminal
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
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- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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- A61P5/08—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH for decreasing, blocking or antagonising the activity of the anterior pituitary hormones
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- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Gastroenterology & Hepatology (AREA)
- Endocrinology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US18818708P | 2008-08-07 | 2008-08-07 | |
US20061208P | 2008-12-02 | 2008-12-02 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1201844A1 true HK1201844A1 (zh) | 2015-09-11 |
Family
ID=41664130
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK15101504.0A HK1201844A1 (zh) | 2008-08-07 | 2011-10-17 | 端經修飾的葡萄糖依賴性促胰島素多肽 的類似物 |
Country Status (12)
Country | Link |
---|---|
US (2) | US8999940B2 (zh) |
EP (2) | EP2769986A3 (zh) |
JP (3) | JP2011530509A (zh) |
KR (3) | KR101593158B1 (zh) |
CN (2) | CN102171243A (zh) |
AU (1) | AU2009280021B2 (zh) |
BR (1) | BRPI0917580A2 (zh) |
CA (1) | CA2733006A1 (zh) |
EA (1) | EA020091B1 (zh) |
HK (1) | HK1201844A1 (zh) |
MX (2) | MX339137B (zh) |
WO (1) | WO2010016944A2 (zh) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010016940A2 (en) | 2008-08-07 | 2010-02-11 | Ipsen Pharma S.A.S. | Analogues of glucose-dependent insulinotropic polypeptide |
KR20110043688A (ko) | 2008-08-07 | 2011-04-27 | 입센 파마 에스.에이.에스 | 포도당 의존적인 인슐린 분비 자극성 폴리펩타이드 유사체 |
JP2011530509A (ja) * | 2008-08-07 | 2011-12-22 | イプセン ファルマ ソシエテ パール アクシオン サンプリフィエ | N末端において修飾されたグルコース依存性インスリン分泌刺激ポリペプチド(gip)のアナログ |
WO2011018613A1 (en) | 2009-08-10 | 2011-02-17 | Ucl Business Plc | Functionalisation of solid substrates |
AR080592A1 (es) * | 2010-03-26 | 2012-04-18 | Lilly Co Eli | Peptido con actividad para el gip-r y glp-1-r, formulacion famaceutica que lo comprende, su uso para preparar un medicamento util para el tratamiento de diabetes mellitus y para inducir la perdida de peso |
DE102010015123A1 (de) | 2010-04-16 | 2011-10-20 | Sanofi-Aventis Deutschland Gmbh | Benzylamidische Diphenylazetidinone, diese Verbindungen enthaltende Arzneimittel und deren Verwendung |
US8530413B2 (en) | 2010-06-21 | 2013-09-10 | Sanofi | Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments |
TW201215387A (en) | 2010-07-05 | 2012-04-16 | Sanofi Aventis | Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament |
TW201221505A (en) | 2010-07-05 | 2012-06-01 | Sanofi Sa | Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament |
TW201215388A (en) | 2010-07-05 | 2012-04-16 | Sanofi Sa | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments |
US9023986B2 (en) * | 2010-10-25 | 2015-05-05 | Hoffmann-La Roche Inc. | Glucose-dependent insulinotropic peptide analogs |
EP2567959B1 (en) | 2011-09-12 | 2014-04-16 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
WO2013037390A1 (en) | 2011-09-12 | 2013-03-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
WO2013045413A1 (en) | 2011-09-27 | 2013-04-04 | Sanofi | 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
FR2994848B1 (fr) | 2012-08-30 | 2014-08-22 | Univ Paris Curie | Traitement de l'arthrose par les hormones incretines ou leurs analogues |
SE536738C2 (sv) | 2012-11-02 | 2014-07-01 | Heatcore Ab | Värmeväxlarplatta för plattvärmeväxlare, plattvärmeväxlare innefattande sådana värmeväxlarplattor och anordning för uppvärmning innefattande plattvärmeväxlaren |
CN116440247A (zh) | 2013-03-01 | 2023-07-18 | 康德生物医疗有限公司 | 治疗线粒体疾病的方法 |
ES2750258T3 (es) | 2013-03-01 | 2020-03-25 | Stealth Biotherapeutics Corp | Métodos y composiciones para la prevención o tratamiento del síndrome de Barth |
GEP201706762B (en) * | 2013-05-28 | 2017-10-25 | Takeda Pharmaceuticals Co | Peptide compound |
US10047395B2 (en) | 2013-06-26 | 2018-08-14 | Stealth Biotherapeutics Corp | Methods and compositions for detecting and diagnosing diseases and conditions |
PL3189072T3 (pl) | 2014-09-05 | 2019-04-30 | Univ Copenhagen | Analogi peptydowe gip |
JP2018012644A (ja) * | 2014-11-26 | 2018-01-25 | 武田薬品工業株式会社 | ペプチド化合物 |
CN105061566A (zh) * | 2015-09-05 | 2015-11-18 | 苏州普罗达生物科技有限公司 | 拟胰岛素多肽及其应用 |
NZ743474A (en) | 2015-12-23 | 2023-03-31 | Amgen Inc | Method of treating or ameliorating metabolic disorders using binding proteins for gastric inhibitory peptide receptor (gipr) in combination with glp-1 agonists |
US10501516B2 (en) | 2016-05-24 | 2019-12-10 | Takeda Pharmaceutical Company Limited | Peptide compound |
EP3538541A4 (en) * | 2016-11-09 | 2020-12-02 | Nanyang Technological University | MANUFACTURING AND USE OF GINSENTIDES AND GINSENTID-LIKE PEPTIDES |
JOP20190177A1 (ar) | 2017-01-17 | 2019-07-16 | Amgen Inc | طريقة لعلاج أو تحسين اضطرابات أيضية باستخدام مساعدات مستقبل glp-1 مقترنة بمناهضات لمستقبل ببتيد مثبط معوي (gipr) |
JOP20180028A1 (ar) | 2017-03-31 | 2019-01-30 | Takeda Pharmaceuticals Co | مركب ببتيد |
US11572399B2 (en) | 2017-05-31 | 2023-02-07 | University Of Copenhagen | Long-acting GIP peptide analogues |
PE20210473A1 (es) | 2018-05-04 | 2021-03-08 | Novo Nordisk As | Derivados de gip y usos de estos |
CN110684082B (zh) * | 2019-10-08 | 2021-12-10 | 江苏诺泰澳赛诺生物制药股份有限公司 | Gip和glp-1双激动多肽化合物及药学上可接受的盐与用途 |
AU2021243671A1 (en) * | 2020-03-25 | 2022-10-13 | Takeda Pharmaceutical Company Limited | GIF receptor agonist peptide compounds and uses thereof |
Family Cites Families (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4562175A (en) * | 1984-02-03 | 1985-12-31 | Ding Chang | Synthetic peptides |
US5672659A (en) | 1993-01-06 | 1997-09-30 | Kinerton Limited | Ionic molecular conjugates of biodegradable polyesters and bioactive polypeptides |
US5595760A (en) | 1994-09-02 | 1997-01-21 | Delab | Sustained release of peptides from pharmaceutical compositions |
US5665702A (en) | 1995-06-06 | 1997-09-09 | Biomeasure Incorporated | Ionic molecular conjugates of N-acylated derivatives of poly(2-amino-2-deoxy-D-glucose) and polypeptides |
US5916883A (en) | 1996-11-01 | 1999-06-29 | Poly-Med, Inc. | Acylated cyclodextrin derivatives |
US7091183B1 (en) * | 1996-12-03 | 2006-08-15 | Boston Medical Center Corporation | Specific antagonists for glucose-dependent insulinotropic polypeptide (GIP) |
AU5518798A (en) | 1996-12-03 | 1998-06-29 | Trustees Of Boston University | Specific antagonists for glucose-dependent insulinotropic polypeptide (gip) |
ATE262926T1 (de) | 1998-01-29 | 2004-04-15 | Poly Med Inc | Asorbierbare mikropartikel |
WO2000004916A1 (en) | 1998-07-23 | 2000-02-03 | Societe De Conseils De Recherches Et D'applications Scientifiques Sas | Encapsulation of water soluble peptides |
AR020650A1 (es) | 1998-08-10 | 2002-05-22 | Poly Med Inc | Polimeros fosforilados y conjugados de los mismos |
EP1144013B1 (en) | 1998-11-02 | 2007-03-21 | Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. | Lactone bearing absorbable polymers |
DE69922043T2 (de) * | 1998-12-07 | 2005-11-24 | Société de Conseils de Recherches et d'Applications Scientifiques S.A.S. | Glp-1 analoge |
PL189664B1 (pl) | 1998-12-07 | 2005-09-30 | Sod Conseils Rech Applic | Nowy analog GLP-1, kompozycja farmaceutyczna go zawierająca oraz zastosowanie nowego analogu GLP-1 |
CA2367856C (en) | 1999-03-29 | 2013-10-15 | Uutech Limited | Analogs of gastric inhibitory peptide and their use for treatment of diabetes |
US20050272652A1 (en) * | 1999-03-29 | 2005-12-08 | Gault Victor A | Peptide analogues of GIP for treatment of diabetes, insulin resistance and obesity |
GB0404124D0 (en) * | 2004-02-25 | 2004-03-31 | Univ Ulster | Antagonists of GIP |
WO2002082047A2 (en) * | 2001-04-06 | 2002-10-17 | California Institute Of Technology | High throughput screening of crystallization of materials |
TWI284539B (en) * | 2001-07-30 | 2007-08-01 | Epix Pharm Inc | A method for making a magnetic resonance (MR) imaging agent, a MR imaging contrast agent, a method for altering stability of a peptide and a modified peptide |
US20030232761A1 (en) * | 2002-03-28 | 2003-12-18 | Hinke Simon A. | Novel analogues of glucose-dependent insulinotropic polypeptide |
US20060189520A1 (en) | 2002-10-22 | 2006-08-24 | Brand Stephen J | Treatment of diabetes |
RU2339398C2 (ru) * | 2002-10-22 | 2008-11-27 | Уэйрейта Фармасьютиклз, Инк. | Лечение диабета |
JP5216216B2 (ja) * | 2003-11-13 | 2013-06-19 | ハンミ サイエンス カンパニー リミテッド | 免疫グロブリンFc領域をキャリアとして含む薬剤学的組成物 |
EP2210900A3 (en) * | 2003-12-16 | 2010-08-11 | Ipsen Pharma | Analogues of GLP-1 |
EP2392595A1 (en) * | 2005-02-11 | 2011-12-07 | Amylin Pharmaceuticals Inc. | GIP analog and hybrid polypeptides with selectable properties |
WO2006121904A1 (en) * | 2005-05-06 | 2006-11-16 | Bayer Pharmaceuticals Corporation | Glucose-dependent insulinotropic polypeptide (gip) receptor agonists and their pharmacological methods of use |
CA2622069A1 (en) * | 2005-09-08 | 2007-03-15 | Uutech Limited | Treatment of diabetes related obesity |
WO2007028632A2 (en) * | 2005-09-08 | 2007-03-15 | Uutech Limited | Analogs of gastric inhibitory polypeptide as a treatment for age related decreased pancreatic beta cell function |
JPWO2007049695A1 (ja) | 2005-10-26 | 2009-04-30 | 中外製薬株式会社 | 凝集性glp−1アナログおよび徐放性医薬組成物 |
EP2057188B1 (en) * | 2006-08-17 | 2013-07-31 | Amylin Pharmaceuticals, LLC | Dpp-iv resistant gip hybrid polypeptides with selectable properties |
JP2011530509A (ja) * | 2008-08-07 | 2011-12-22 | イプセン ファルマ ソシエテ パール アクシオン サンプリフィエ | N末端において修飾されたグルコース依存性インスリン分泌刺激ポリペプチド(gip)のアナログ |
-
2009
- 2009-08-07 JP JP2011522071A patent/JP2011530509A/ja active Pending
- 2009-08-07 CA CA2733006A patent/CA2733006A1/en not_active Abandoned
- 2009-08-07 AU AU2009280021A patent/AU2009280021B2/en not_active Ceased
- 2009-08-07 CN CN2009801394417A patent/CN102171243A/zh active Pending
- 2009-08-07 CN CN201410406367.3A patent/CN104231070B/zh not_active Expired - Fee Related
- 2009-08-07 BR BRPI0917580A patent/BRPI0917580A2/pt active Search and Examination
- 2009-08-07 KR KR1020157011870A patent/KR101593158B1/ko not_active IP Right Cessation
- 2009-08-07 KR KR1020137031534A patent/KR20130133103A/ko active Application Filing
- 2009-08-07 EP EP13195741.7A patent/EP2769986A3/en not_active Withdrawn
- 2009-08-07 EP EP09805295A patent/EP2318433A4/en not_active Withdrawn
- 2009-08-07 US US13/057,966 patent/US8999940B2/en not_active Expired - Fee Related
- 2009-08-07 MX MX2014009529A patent/MX339137B/es unknown
- 2009-08-07 EA EA201170305A patent/EA020091B1/ru not_active IP Right Cessation
- 2009-08-07 WO PCT/US2009/004559 patent/WO2010016944A2/en active Application Filing
- 2009-08-07 MX MX2011001032A patent/MX2011001032A/es not_active Application Discontinuation
- 2009-08-07 KR KR1020117003756A patent/KR20110043689A/ko active Application Filing
-
2011
- 2011-10-17 HK HK15101504.0A patent/HK1201844A1/zh unknown
-
2013
- 2013-10-02 JP JP2013207223A patent/JP5986550B2/ja not_active Expired - Fee Related
-
2015
- 2015-03-05 US US14/639,210 patent/US20150175665A1/en not_active Abandoned
-
2016
- 2016-02-19 JP JP2016029639A patent/JP2016175892A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
JP5986550B2 (ja) | 2016-09-06 |
WO2010016944A2 (en) | 2010-02-11 |
CN104231070A (zh) | 2014-12-24 |
US20150175665A1 (en) | 2015-06-25 |
EP2769986A2 (en) | 2014-08-27 |
CA2733006A1 (en) | 2010-02-11 |
EA201170305A1 (ru) | 2011-10-31 |
KR20130133103A (ko) | 2013-12-05 |
AU2009280021B2 (en) | 2012-10-04 |
EP2318433A4 (en) | 2012-08-08 |
AU2009280021A1 (en) | 2010-02-11 |
EA020091B1 (ru) | 2014-08-29 |
EP2318433A2 (en) | 2011-05-11 |
CN104231070B (zh) | 2017-09-01 |
US20110136725A1 (en) | 2011-06-09 |
JP2011530509A (ja) | 2011-12-22 |
MX2011001032A (es) | 2011-08-12 |
JP2014051501A (ja) | 2014-03-20 |
MX339137B (es) | 2016-05-13 |
EP2769986A3 (en) | 2014-11-26 |
BRPI0917580A2 (pt) | 2016-10-11 |
KR101593158B1 (ko) | 2016-02-12 |
KR20150056668A (ko) | 2015-05-26 |
JP2016175892A (ja) | 2016-10-06 |
WO2010016944A3 (en) | 2010-04-29 |
US8999940B2 (en) | 2015-04-07 |
CN102171243A (zh) | 2011-08-31 |
KR20110043689A (ko) | 2011-04-27 |
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