HK1201841A1 - 穩定固體形式的瑞加德松 - Google Patents

穩定固體形式的瑞加德松

Info

Publication number
HK1201841A1
HK1201841A1 HK15102255.9A HK15102255A HK1201841A1 HK 1201841 A1 HK1201841 A1 HK 1201841A1 HK 15102255 A HK15102255 A HK 15102255A HK 1201841 A1 HK1201841 A1 HK 1201841A1
Authority
HK
Hong Kong
Prior art keywords
regadenoson
solid forms
stable solid
stable
forms
Prior art date
Application number
HK15102255.9A
Other languages
English (en)
Inventor
Paride Grisenti
Reza Elahi Shahrzad
Giuseppe Guazzi
Maria Argese
Original Assignee
Euticals Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euticals Spa filed Critical Euticals Spa
Publication of HK1201841A1 publication Critical patent/HK1201841A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/167—Purine radicals with ribosyl as the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
HK15102255.9A 2013-04-11 2015-03-05 穩定固體形式的瑞加德松 HK1201841A1 (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP13163400.8A EP2789624B1 (en) 2013-04-11 2013-04-11 Stable solid forms of regadenoson

Publications (1)

Publication Number Publication Date
HK1201841A1 true HK1201841A1 (zh) 2015-09-11

Family

ID=48050597

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15102255.9A HK1201841A1 (zh) 2013-04-11 2015-03-05 穩定固體形式的瑞加德松

Country Status (6)

Country Link
US (1) US10144756B2 (zh)
EP (3) EP2789624B1 (zh)
CN (1) CN105121453B (zh)
ES (1) ES2837751T3 (zh)
HK (1) HK1201841A1 (zh)
WO (1) WO2014167046A1 (zh)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016126734A1 (en) * 2015-02-06 2016-08-11 Apicore Us Llc Process of making regadenoson and novel polymorph thereof
US9809617B2 (en) * 2015-07-03 2017-11-07 Shanghai Ziyuan Pharmaceutical Co., Ltd. Crystal form of regadenoson and preparation method thereof
WO2017042837A2 (en) * 2015-09-11 2017-03-16 Sun Pharmaceutical Industries Limited Stable crystalline form of regadenoson
US10392417B2 (en) 2016-11-04 2019-08-27 Apicore Us Llc Polymorph of regadenoson and process for preparation thereof
CN110117305B (zh) * 2018-02-06 2023-06-02 上海键合医药科技有限公司 一种瑞加德松纯化方法及其新晶型
WO2019191389A1 (en) * 2018-03-29 2019-10-03 Johnson Matthey Public Limited Company Solid-state forms of regadenoson, their use and preparation
US10815265B2 (en) * 2018-06-29 2020-10-27 Usv Private Limited Process for preparation of regadenoson and polymorphs thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6403567B1 (en) 1999-06-22 2002-06-11 Cv Therapeutics, Inc. N-pyrazole A2A adenosine receptor agonists
KR101494125B1 (ko) * 2006-02-03 2015-02-16 길리애드 사이언시즈, 인코포레이티드 Ａ2ａ-아데노신 수용체 효능제 및 이의 다형체의 제조 방법
RU2459626C2 (ru) * 2006-09-01 2012-08-27 Гайлид Сайэнсиз, Инк. Способы и композиции, повышающие переносимость пациентом методов визуализации миокарда
US8859522B2 (en) * 2011-04-27 2014-10-14 Reliable Biopharmaceutical Corporation Processes for the preparation of regadenoson and a new crystalline form thereof
CZ304053B6 (cs) * 2011-08-22 2013-09-04 Farmak, A. S. Zpusob prípravy 2-[4-[(methylamino)karbonyl]-1-H-pyrazol-1-yl]adenosinu monohydrátu

Also Published As

Publication number Publication date
EP3760637A2 (en) 2021-01-06
WO2014167046A1 (en) 2014-10-16
EP2789624B1 (en) 2020-09-23
EP2984099A1 (en) 2016-02-17
CN105121453B (zh) 2019-05-28
EP2789624A1 (en) 2014-10-15
ES2837751T3 (es) 2021-07-01
US10144756B2 (en) 2018-12-04
US20160024137A1 (en) 2016-01-28
CN105121453A (zh) 2015-12-02
EP3760637A3 (en) 2021-04-07

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