HK1201072A1 - 體外雙相軟骨-骨構建物 - Google Patents

體外雙相軟骨-骨構建物

Info

Publication number
HK1201072A1
HK1201072A1 HK15101554.9A HK15101554A HK1201072A1 HK 1201072 A1 HK1201072 A1 HK 1201072A1 HK 15101554 A HK15101554 A HK 15101554A HK 1201072 A1 HK1201072 A1 HK 1201072A1
Authority
HK
Hong Kong
Prior art keywords
vitro
bone construct
phasic cartilage
phasic
cartilage
Prior art date
Application number
HK15101554.9A
Other languages
English (en)
Inventor
‧羅索夫斯基
‧法特稀-瓦爾卡尼
‧勞斯特爾
‧馬克思
Original Assignee
Tissuse Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tissuse Gmbh filed Critical Tissuse Gmbh
Publication of HK1201072A1 publication Critical patent/HK1201072A1/zh

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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0697—Artificial constructs associating cells of different lineages, e.g. tissue equivalents
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    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/10—Ceramics or glasses
    • A—HUMAN NECESSITIES
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    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3834—Cells able to produce different cell types, e.g. hematopoietic stem cells, mesenchymal stem cells, marrow stromal cells, embryonic stem cells
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    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
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    • A—HUMAN NECESSITIES
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    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0655—Chondrocytes; Cartilage
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
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    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
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    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
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    • G01N33/5082—Supracellular entities, e.g. tissue, organisms
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    • G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • A—HUMAN NECESSITIES
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    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/06—Materials or treatment for tissue regeneration for cartilage reconstruction, e.g. meniscus
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    • C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
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    • C12N2502/1317—Chondrocytes
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    • C12N2502/1352—Mesenchymal stem cells
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    • C12N2506/13—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
    • C12N2506/1346—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells
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HK15101554.9A 2012-02-29 2015-02-12 體外雙相軟骨-骨構建物 HK1201072A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12157484.2A EP2634251A1 (en) 2012-02-29 2012-02-29 3D in vitro bi-phasic cartilage-bone construct
PCT/EP2013/054030 WO2013127921A1 (en) 2012-02-29 2013-02-28 3d in vitro bi-phasic cartilage-bone construct

Publications (1)

Publication Number Publication Date
HK1201072A1 true HK1201072A1 (zh) 2015-08-21

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Application Number Title Priority Date Filing Date
HK15101554.9A HK1201072A1 (zh) 2012-02-29 2015-02-12 體外雙相軟骨-骨構建物

Country Status (12)

Country Link
US (1) US9856458B2 (zh)
EP (2) EP2634251A1 (zh)
JP (1) JP2015511482A (zh)
CN (1) CN104204191B (zh)
DK (1) DK2834348T3 (zh)
ES (1) ES2739201T3 (zh)
HK (1) HK1201072A1 (zh)
HU (1) HUE044561T2 (zh)
RU (1) RU2615439C2 (zh)
SG (2) SG10201607179SA (zh)
TR (1) TR201911258T4 (zh)
WO (1) WO2013127921A1 (zh)

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* Cited by examiner, † Cited by third party
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US9719068B2 (en) 2010-05-06 2017-08-01 Children's Hospital Medical Center Methods and systems for converting precursor cells into intestinal tissues through directed differentiation
US10174289B2 (en) 2014-05-28 2019-01-08 Children's Hospital Medical Center Methods and systems for converting precursor cells into gastric tissues through directed differentiation
WO2016061464A1 (en) 2014-10-17 2016-04-21 Children's Hospital Center, D/B/A Cincinnati Children's Hospital Medical Center In vivo model of human small intetine using pluripotent stem cells and methods of making and using same
US9238090B1 (en) 2014-12-24 2016-01-19 Fettech, Llc Tissue-based compositions
CN110582564A (zh) * 2015-09-15 2019-12-17 新加坡科技研究局 从人类多能干细胞衍生肝类器官
KR101733137B1 (ko) * 2015-12-30 2017-05-08 (주)엑셀세라퓨틱스 연골조직 제조를 위한 3차원 오가노이드 블록 제작 방법
CN105754855B (zh) * 2016-04-12 2018-08-21 中国航天员科研训练中心 一种流加式两层细胞共培养器官芯片
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US9856458B2 (en) 2018-01-02
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