HK1201068A1 - Peptide antagonists of the calcitonin cgrp family of peptide hormones and their use cgrp - Google Patents
Peptide antagonists of the calcitonin cgrp family of peptide hormones and their use cgrpInfo
- Publication number
- HK1201068A1 HK1201068A1 HK15101555.8A HK15101555A HK1201068A1 HK 1201068 A1 HK1201068 A1 HK 1201068A1 HK 15101555 A HK15101555 A HK 15101555A HK 1201068 A1 HK1201068 A1 HK 1201068A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- cgrp
- peptide
- calcitonin
- family
- antagonists
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/57527—Calcitonin gene related peptide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/225—Calcitonin gene related peptide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/23—Calcitonins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
- A61P5/22—Drugs for disorders of the endocrine system of the parathyroid hormones for decreasing, blocking or antagonising the activity of calcitonin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/585—Calcitonins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Endocrinology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261591236P | 2012-01-26 | 2012-01-26 | |
| PCT/US2013/023260 WO2013112912A1 (en) | 2012-01-26 | 2013-01-25 | Peptide antagonists of the calcitonin cgrp family of peptide hormones and their use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1201068A1 true HK1201068A1 (en) | 2015-08-21 |
Family
ID=47682066
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK15101555.8A HK1201068A1 (en) | 2012-01-26 | 2015-02-12 | Peptide antagonists of the calcitonin cgrp family of peptide hormones and their use cgrp |
| HK18109409.6A HK1249915A1 (zh) | 2012-01-26 | 2018-07-20 | 肽激素的降鈣素cgrp家族的肽拮抗劑和它們的用途 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK18109409.6A HK1249915A1 (zh) | 2012-01-26 | 2018-07-20 | 肽激素的降鈣素cgrp家族的肽拮抗劑和它們的用途 |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US9193776B2 (es) |
| EP (2) | EP3272769B1 (es) |
| JP (3) | JP6025871B2 (es) |
| KR (2) | KR102052983B1 (es) |
| CN (2) | CN108997490A (es) |
| AU (2) | AU2013211929B2 (es) |
| CA (1) | CA2861392C (es) |
| DK (1) | DK2807187T3 (es) |
| ES (2) | ES2819825T3 (es) |
| HK (2) | HK1201068A1 (es) |
| IL (2) | IL233655A (es) |
| MX (1) | MX347229B (es) |
| NO (1) | NO2864579T3 (es) |
| RU (2) | RU2624016C2 (es) |
| WO (1) | WO2013112912A1 (es) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3272769B1 (en) | 2012-01-26 | 2020-06-17 | Christopher J. Soares | Peptide antagonists of the calcitonin cgrp family of peptide hormones and their use |
| JP6538682B2 (ja) * | 2013-07-30 | 2019-07-03 | ソアレス クリストファー ジェイ． | Ｃｇｒｐアゴニストペプチド |
| JO3669B1 (ar) * | 2015-01-06 | 2020-08-27 | Ferring Bv | بيبتيدات مضَادَّة لببتيد المرتبط بجين الكالسيتونين |
| US11034745B2 (en) * | 2016-01-04 | 2021-06-15 | Adepthera Llc | Superagonist polypeptide analogs of adrenomedullin and intermedin peptide hormones |
| WO2018045083A1 (en) * | 2016-09-02 | 2018-03-08 | Soares Christopher J | Use of cgrp receptor antagonists in neuroprotection and neurological disorders |
| CA2967616A1 (en) * | 2016-09-19 | 2018-03-19 | The Governors Of The University Of Alberta | Brain penetrant amylin receptor based peptides for alzheimer's disease |
| WO2019087161A1 (en) * | 2017-11-06 | 2019-05-09 | Auckland Uniservices Limited | Peptide conjugate cgrp receptor antagonists and methods of preparation and uses thereof |
| JP7214102B2 (ja) * | 2019-01-18 | 2023-01-30 | 株式会社大一商会 | 遊技機 |
| JP7214104B2 (ja) * | 2019-01-18 | 2023-01-30 | 株式会社大一商会 | 遊技機 |
| JP7214100B2 (ja) * | 2019-01-18 | 2023-01-30 | 株式会社大一商会 | 遊技機 |
| CN116456981A (zh) * | 2020-11-19 | 2023-07-18 | 辉瑞爱尔兰制药公司 | 用于改善的grp抑制剂递送的组合物 |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2046920B1 (es) | 1969-06-19 | 1974-05-03 | Citizen Watch Co Ltd | |
| US3940475A (en) | 1970-06-11 | 1976-02-24 | Biological Developments, Inc. | Radioimmune method of assaying quantitatively for a hapten |
| US4179337A (en) | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
| JPS6023084B2 (ja) | 1979-07-11 | 1985-06-05 | 味の素株式会社 | 代用血液 |
| NO812612L (no) | 1980-08-06 | 1982-02-08 | Ferring Pharma Ltd | Enzym-inhibitorer. |
| US4640835A (en) | 1981-10-30 | 1987-02-03 | Nippon Chemiphar Company, Ltd. | Plasminogen activator derivatives |
| CH657779A5 (de) | 1982-10-05 | 1986-09-30 | Sandoz Ag | Galenische zusammensetzungen enthaltend calcitonin. |
| IT1164225B (it) | 1983-05-13 | 1987-04-08 | Anic Spa | Analoghi retro-invertiti del pentapeptide potenziante la bradichina bpp5a e metodi per la loro preparazione |
| US4530838A (en) | 1983-07-08 | 1985-07-23 | The Salk Institute For Biological Studies | Synthetic calcitonin-gene-related peptides for lowering blood pressure or gastric acid secretion in mammals |
| US4496689A (en) | 1983-12-27 | 1985-01-29 | Miles Laboratories, Inc. | Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer |
| DE3675588D1 (de) | 1985-06-19 | 1990-12-20 | Ajinomoto Kk | Haemoglobin, das an ein poly(alkenylenoxid) gebunden ist. |
| JPS62129297A (ja) * | 1985-08-09 | 1987-06-11 | Toyo Jozo Co Ltd | カルシトニン遺伝子関連ペプチド誘導体 |
| JPS62231168A (ja) | 1986-03-21 | 1987-10-09 | ハイブリテツク・インコ−ポレイテツド | アナライト−レセプタ−分析用内部標準を設けるための改良法 |
| US4791192A (en) | 1986-06-26 | 1988-12-13 | Takeda Chemical Industries, Ltd. | Chemically modified protein with polyethyleneglycol |
| US6552170B1 (en) | 1990-04-06 | 2003-04-22 | Amgen Inc. | PEGylation reagents and compounds formed therewith |
| US5206161A (en) | 1991-02-01 | 1993-04-27 | Genentech, Inc. | Human plasma carboxypeptidase B |
| WO1993025221A1 (en) | 1992-06-11 | 1993-12-23 | Alkermes Controlled Therapeutics, Inc. | Erythropoietin drug delivery system |
| US5354934A (en) | 1993-02-04 | 1994-10-11 | Amgen Inc. | Pulmonary administration of erythropoietin |
| AU6524794A (en) | 1993-03-24 | 1994-10-11 | Amylin Pharmaceuticals, Inc. | Cloned receptors and methods for screening |
| US5698401A (en) | 1995-11-14 | 1997-12-16 | Abbott Laboratories | Use of nuclear magnetic resonance to identify ligands to target biomolecules |
| US5910482A (en) * | 1996-03-19 | 1999-06-08 | Board Of Regents, The University Of Texas System | Treatment or prevention of preeclampsia, eclampsia with calcitonin gene related peptide, CGRP analog, progestational agent, nitric oxide source, and cyclooxygenase inhibitor |
| WO1997041223A1 (en) | 1996-04-15 | 1997-11-06 | The University Of Miami | Molecular clone of cgrp receptor component protein and uses thereof |
| US20050054557A1 (en) | 2002-05-09 | 2005-03-10 | Goldberg Michael M. | Compositions for delivering parathyroid hormone and calcitonin |
| WO2004084859A2 (en) | 2003-03-21 | 2004-10-07 | Nastech Pharmaceutical Company Inc. | Nasal calcitonin formulations containing chlorobutanol |
| US20060286129A1 (en) | 2003-12-19 | 2006-12-21 | Emisphere Technologies, Inc. | Oral GLP-1 formulations |
| CA2556226A1 (en) * | 2004-02-11 | 2006-08-10 | Amylin Pharmaceuticals, Inc. | Amylin family peptides and methods for making and using them |
| DK1814590T4 (da) | 2004-11-01 | 2014-02-24 | Amylin Pharmaceuticals Llc | Behandling af obesitet og beslægtede sygdomme. |
| US8263545B2 (en) * | 2005-02-11 | 2012-09-11 | Amylin Pharmaceuticals, Inc. | GIP analog and hybrid polypeptides with selectable properties |
| AU2006213607A1 (en) * | 2005-02-11 | 2006-08-17 | Amylin Pharmaceuticals, Llc | GIP analog and hybrid polypeptides with selectable properties |
| JP5114381B2 (ja) * | 2005-03-31 | 2013-01-09 | アミリン・ファーマシューティカルズ，インコーポレイテッド | 精神疾患および障害治療用アミリンおよびアミリンアゴニスト |
| CN101208098A (zh) * | 2005-03-31 | 2008-06-25 | 安米林药品公司 | 用于治疗精神病和精神障碍的胰淀素和胰淀素激动剂 |
| EP1954313A1 (en) * | 2005-11-01 | 2008-08-13 | Amylin Pharmaceuticals, Inc. | Treatment of obesity and related disorders |
| WO2007055743A2 (en) * | 2005-11-01 | 2007-05-18 | Amylin Pharmaceuticals, Inc. | Treatment of obesity and related disorders |
| BRPI0618705B8 (pt) * | 2005-11-14 | 2021-05-25 | Labrys Biologics Inc | anticorpos antagonistas humanizados direcionados contra peptídeo relacionado ao gene da calcitonina, composição farmacêutica e uso dos mesmos |
| EA201070609A1 (ru) | 2007-11-14 | 2010-12-30 | Амилин Фармасьютикалз, Инк. | Способы лечения ожирения и ассоциированных с ожирением заболеваний и расстройств |
| US8748375B2 (en) | 2009-03-17 | 2014-06-10 | Amylin Pharmaceuticals, Llc | Methods for affecting body composition using amylin agonists |
| US20140249076A1 (en) | 2011-10-18 | 2014-09-04 | Astrazeneca Pharmaceuticals Lp | Amylin-calcitonin chimeric peptides conjugated to duration enhancing moieties |
| EP3272769B1 (en) | 2012-01-26 | 2020-06-17 | Christopher J. Soares | Peptide antagonists of the calcitonin cgrp family of peptide hormones and their use |
| SI2820016T1 (sl) | 2012-02-27 | 2017-11-30 | Bristol-Myers Squibb Company | N-(5s,6s,9r)-5-amino-6-(2,3-difluorofenil)-6,7,8,9-tetrahidro-5h- ciklohepta (b)piridin-9-il-4-(2-okso-2, 3-dihidro-1h-imidazo(4,5-b) piridin-1-il) piperidin-1-karboksilat, hemisulfatna sol |
-
2013
- 2013-01-25 EP EP17175988.9A patent/EP3272769B1/en active Active
- 2013-01-25 US US13/821,936 patent/US9193776B2/en active Active
- 2013-01-25 KR KR1020177016079A patent/KR102052983B1/ko active IP Right Grant
- 2013-01-25 AU AU2013211929A patent/AU2013211929B2/en active Active
- 2013-01-25 RU RU2014131605A patent/RU2624016C2/ru active
- 2013-01-25 DK DK13703494.8T patent/DK2807187T3/en active
- 2013-01-25 CN CN201810931542.9A patent/CN108997490A/zh active Pending
- 2013-01-25 ES ES17175988T patent/ES2819825T3/es active Active
- 2013-01-25 CN CN201380010942.1A patent/CN104271596B/zh active Active
- 2013-01-25 KR KR1020147023782A patent/KR101855242B1/ko active IP Right Grant
- 2013-01-25 CA CA2861392A patent/CA2861392C/en active Active
- 2013-01-25 ES ES13703494.8T patent/ES2641325T3/es active Active
- 2013-01-25 WO PCT/US2013/023260 patent/WO2013112912A1/en active Application Filing
- 2013-01-25 MX MX2014008960A patent/MX347229B/es active IP Right Grant
- 2013-01-25 JP JP2014554880A patent/JP6025871B2/ja active Active
- 2013-01-25 EP EP13703494.8A patent/EP2807187B1/en active Active
- 2013-06-18 NO NO13806163A patent/NO2864579T3/no unknown
-
2014
- 2014-07-15 IL IL233655A patent/IL233655A/en active IP Right Grant
-
2015
- 2015-02-12 HK HK15101555.8A patent/HK1201068A1/xx unknown
- 2015-11-20 US US14/948,032 patent/US20160145315A1/en not_active Abandoned
-
2016
- 2016-07-18 AU AU2016205801A patent/AU2016205801A1/en not_active Abandoned
- 2016-10-07 JP JP2016199234A patent/JP6411425B2/ja active Active
-
2017
- 2017-04-03 US US15/478,053 patent/US10370425B2/en active Active
- 2017-05-28 IL IL252555A patent/IL252555B/en active IP Right Grant
- 2017-06-06 RU RU2017119773A patent/RU2742826C2/ru active
-
2018
- 2018-07-20 HK HK18109409.6A patent/HK1249915A1/zh unknown
- 2018-09-21 JP JP2018177504A patent/JP2019006821A/ja active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HK1249915A1 (zh) | 肽激素的降鈣素cgrp家族的肽拮抗劑和它們的用途 | |
| ZA201503146B (en) | Il-6 antagonists and uses thereof | |
| IL244810A0 (en) | Stabilized polypeptides and their uses | |
| HK1210790A1 (en) | Modified factor polypeptides and uses thereof | |
| IL244813A0 (en) | A compound with agonistic activity for the somatostatin receptor and its medicinal use | |
| IL237135A0 (en) | Peptide library and their uses | |
| PT3058936T (pt) | Composição peptídica e respetivos usos | |
| PT2855506T (pt) | Péptido e utilização do mesmo | |
| HK1211042A1 (en) | Inflammation-enabling polypeptides and uses thereof | |
| HK1201050A1 (en) | Polypeptides and their use | |
| HK1220474A1 (zh) | 干擾素α和ω抗體拮抗劑 | |
| HK1210079A1 (en) | Biglycan variant polypeptides and methods of use | |
| ZA201504462B (en) | TGFß-DERIVED POLYPEPTIDES AND USES THEREOF | |
| EP2918600A4 (en) | NEW PEPTIDE AND ITS USE | |
| GB201322869D0 (en) | Therapeutic agents and delivery with microspheres | |
| EP3006564A4 (en) | NEW PEPTIDE AND ITS USE | |
| LT2813502T (lt) | Bradikinino receptorių antagonistai ir juos turinčios farmacinės kompozicijos |