HK1200500A1 - A method to identify asymptomatic high-risk individuals with early stage lung cancer by means of detecting mirnas in biologic fluids mirna - Google Patents

A method to identify asymptomatic high-risk individuals with early stage lung cancer by means of detecting mirnas in biologic fluids mirna

Info

Publication number
HK1200500A1
HK1200500A1 HK15100915.5A HK15100915A HK1200500A1 HK 1200500 A1 HK1200500 A1 HK 1200500A1 HK 15100915 A HK15100915 A HK 15100915A HK 1200500 A1 HK1200500 A1 HK 1200500A1
Authority
HK
Hong Kong
Prior art keywords
mirna
lung cancer
early stage
risk individuals
stage lung
Prior art date
Application number
HK15100915.5A
Other languages
English (en)
Chinese (zh)
Inventor
‧比安基
‧尼卡西奧
‧馬爾奇
‧迪費奧雷
Original Assignee
Fond Istituto Firc Di Oncologia Molecolare
Univ Degli Studi Milano
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fond Istituto Firc Di Oncologia Molecolare, Univ Degli Studi Milano filed Critical Fond Istituto Firc Di Oncologia Molecolare
Publication of HK1200500A1 publication Critical patent/HK1200500A1/xx

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
HK15100915.5A 2010-12-30 2015-01-27 A method to identify asymptomatic high-risk individuals with early stage lung cancer by means of detecting mirnas in biologic fluids mirna HK1200500A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201061428363P 2010-12-30 2010-12-30
EP11160387A EP2505663A1 (en) 2011-03-30 2011-03-30 A method to identify asymptomatic high-risk individuals with early stage lung cancer by means of detecting miRNAs in biologic fluids
PCT/EP2011/073868 WO2012089630A1 (en) 2010-12-30 2011-12-22 A METHOD TO IDENTIFY ASYMPTOMATIC HIGH-RISK INDIVIDUALS WITH EARLY STAGE LUNG CANCER BY MEANS OF DETECTING miRNAs IN BIOLOGIC FLUIDS

Publications (1)

Publication Number Publication Date
HK1200500A1 true HK1200500A1 (en) 2015-08-07

Family

ID=44146709

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15100915.5A HK1200500A1 (en) 2010-12-30 2015-01-27 A method to identify asymptomatic high-risk individuals with early stage lung cancer by means of detecting mirnas in biologic fluids mirna

Country Status (5)

Country Link
US (1) US20150057159A1 (xx)
EP (2) EP2505663A1 (xx)
CN (1) CN103958695B (xx)
HK (1) HK1200500A1 (xx)
WO (1) WO2012089630A1 (xx)

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CN103484550B (zh) * 2013-09-30 2014-09-10 中国科学院上海微系统与信息技术研究所 一组肺癌早期诊断用microRNA生物标志物及其应用
PL406989A1 (pl) 2014-01-29 2015-08-03 Gdański Uniwersytet Medyczny Profil mikro RNA we krwi jako test wykrywania raka płuca
WO2016038119A1 (en) * 2014-09-09 2016-03-17 Istituto Europeo Di Oncologia S.R.L. Methods for lung cancer detection
WO2016106643A1 (zh) * 2014-12-31 2016-07-07 深圳华大基因股份有限公司 检测非小细胞肺癌用药相关基因突变的引物及检测方法
CN104593520B (zh) * 2015-02-28 2016-10-05 上海赛安生物医药科技有限公司 一种肺癌miRNA检测试剂盒及其miRNA的应用
PL411561A1 (pl) 2015-03-13 2016-09-26 Gdański Uniwersytet Medyczny Profil mikroRNA skojarzony z profilem markerów białkowych krwi jako test wykrywania raka płuca
CN104846087A (zh) * 2015-05-04 2015-08-19 四川大学华西第二医院 一种用于男性无精症诊断的试剂盒和使用方法
CN104846086A (zh) * 2015-05-04 2015-08-19 四川大学华西第二医院 血浆miR-15b作为分子标记物在精子产生与功能评估中的应用
SG10201910412QA (en) * 2015-05-19 2020-01-30 Wistar Inst Methods and compositions for diagnosing or detecting lung cancers
CN106442991B (zh) * 2015-08-06 2018-07-27 中国人民解放军军事医学科学院生物医学分析中心 用于预测肺腺癌患者预后及判断辅助化疗获益的系统
CN106442990B (zh) * 2015-08-06 2018-07-27 中国人民解放军军事医学科学院生物医学分析中心 用于预测肺鳞癌患者预后的系统
CN105238863A (zh) * 2015-10-29 2016-01-13 中国科学院近代物理研究所 miR-197在作为肝癌检测标志物中的应用
CN105457041B (zh) * 2015-12-09 2020-09-08 上海大学 miR-26a在非小细胞肺癌中的应用
CN107435062B (zh) * 2016-05-25 2020-10-20 上海伯豪医学检验所有限公司 甄别肺部微小结节良恶性的外周血基因标志物及其用途
WO2017219171A1 (zh) * 2016-06-19 2017-12-28 毛侃琅 抑制双 MicroRNA 表达的慢病毒载体的构建及其应用
TWI614629B (zh) * 2016-08-31 2018-02-11 National Central University 預測癌症放射線治療之預後的分析器及方法
CN107043806B (zh) * 2016-12-13 2020-07-07 江苏省疾病预防控制中心 铅暴露工人岗前入职筛选微小rna标志物及其应用
CN106676196B (zh) * 2017-03-10 2019-05-07 上海核盾生物科技有限公司 一种用于诊断重度吸烟人群中肺鳞癌患者的非侵入性标记物及试剂盒
EP4012047A1 (en) 2020-12-11 2022-06-15 Fondazione di Religione e di Culto "Casa Sollievo Della Sofferenza" - Opera di San Pio da Pietrelcina Prognostic method for aggressive lung adenocarcinomas
KR20230117622A (ko) * 2021-01-07 2023-08-08 드림호크 비젼 바이오테크, 인코포레이티드 안구 표면 질환의 치료 방법

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US7943318B2 (en) 2006-01-05 2011-05-17 The Ohio State University Research Foundation Microrna-based methods and compositions for the diagnosis, prognosis and treatment of lung cancer
US8207325B2 (en) 2006-04-03 2012-06-26 Univ. of Copenhagen MicroRNA biomarkers for human breast and lung cancer
US7955848B2 (en) 2006-04-03 2011-06-07 Trustees Of Dartmouth College MicroRNA biomarkers for human breast and lung cancer
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EP2225396A4 (en) 2007-11-30 2011-03-02 Univ Ohio State Res Found PROFILING AND SCREENING OF MICRO-RNA EXPRESSION IN PERIPHERAL BLOOD IN LUNG CANCER
US20110077168A1 (en) 2008-06-17 2011-03-31 Nitzan Rosenfeld Methods for distinguishing between specific types of lung cancers
CN101608232A (zh) 2008-06-18 2009-12-23 中国科学院生物物理研究所 用于筛选和鉴定低丰度小rna表达谱的新型小rna芯片的制备方法和应用
CN101307361A (zh) 2008-07-15 2008-11-19 南京大学 一种Solexa技术鉴定肺癌病人血清中微小核糖核酸的方法
WO2010054233A1 (en) 2008-11-08 2010-05-14 The Wistar Institute Of Anatomy And Biology Biomarkers in peripheral blood mononuclear cells for diagnosing or detecting lung cancers
CN102333888B (zh) 2008-12-24 2013-07-10 姜桥 用于肿瘤样本起源组织分类的基因表达签名
LU91545B1 (en) 2009-03-27 2010-09-28 Univ Luxembourg Mirna as a prognostic diagnostic biomarker and therapeutic agent for breast cancer and other human associated pathologies
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US8911940B2 (en) 2009-07-31 2014-12-16 The Translational Genomics Research Institute Methods of assessing a risk of cancer progression
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CN101638656B (zh) 2009-08-28 2011-05-11 南京医科大学 一种与非小细胞肺癌预后相关的血清/血浆miRNA标志物及其应用

Also Published As

Publication number Publication date
CN103958695B (zh) 2018-07-20
EP2658997A1 (en) 2013-11-06
WO2012089630A1 (en) 2012-07-05
CN103958695A (zh) 2014-07-30
EP2505663A1 (en) 2012-10-03
US20150057159A1 (en) 2015-02-26

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