HK1200210A1 - Valve and splitting system for multi-dimensional liquid analysis - Google Patents

Valve and splitting system for multi-dimensional liquid analysis

Info

Publication number
HK1200210A1
HK1200210A1 HK15100508.8A HK15100508A HK1200210A1 HK 1200210 A1 HK1200210 A1 HK 1200210A1 HK 15100508 A HK15100508 A HK 15100508A HK 1200210 A1 HK1200210 A1 HK 1200210A1
Authority
HK
Hong Kong
Prior art keywords
valve
splitting system
dimensional liquid
liquid analysis
analysis
Prior art date
Application number
HK15100508.8A
Other languages
English (en)
Chinese (zh)
Inventor
Carl Sims
Peter Carr
Marcelo Filgueira
Original Assignee
Univ Minnesota
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Minnesota filed Critical Univ Minnesota
Publication of HK1200210A1 publication Critical patent/HK1200210A1/xx

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/26Conditioning of the fluid carrier; Flow patterns
    • G01N30/38Flow patterns
    • G01N30/46Flow patterns using more than one column
    • G01N30/461Flow patterns using more than one column with serial coupling of separation columns
    • G01N30/463Flow patterns using more than one column with serial coupling of separation columns for multidimensional chromatography
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/04Preparation or injection of sample to be analysed
    • G01N30/06Preparation
    • G01N30/10Preparation using a splitter
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/26Conditioning of the fluid carrier; Flow patterns
    • G01N30/28Control of physical parameters of the fluid carrier
    • G01N30/32Control of physical parameters of the fluid carrier of pressure or speed
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/26Conditioning of the fluid carrier; Flow patterns
    • G01N30/38Flow patterns
    • G01N30/46Flow patterns using more than one column
    • G01N30/461Flow patterns using more than one column with serial coupling of separation columns
    • G01N30/465Flow patterns using more than one column with serial coupling of separation columns with specially adapted interfaces between the columns
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/26Conditioning of the fluid carrier; Flow patterns
    • G01N30/28Control of physical parameters of the fluid carrier
    • G01N30/32Control of physical parameters of the fluid carrier of pressure or speed
    • G01N2030/324Control of physical parameters of the fluid carrier of pressure or speed speed, flow rate
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/62Detectors specially adapted therefor
    • G01N30/72Mass spectrometers
    • G01N30/7233Mass spectrometers interfaced to liquid or supercritical fluid chromatograph

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Sampling And Sample Adjustment (AREA)
HK15100508.8A 2011-03-23 2015-01-16 Valve and splitting system for multi-dimensional liquid analysis HK1200210A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161466739P 2011-03-23 2011-03-23
PCT/US2012/029378 WO2012129076A1 (en) 2011-03-23 2012-03-16 Valve and splitting system for multi-dimensional liquid analysis

Publications (1)

Publication Number Publication Date
HK1200210A1 true HK1200210A1 (en) 2015-07-31

Family

ID=46876161

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15100508.8A HK1200210A1 (en) 2011-03-23 2015-01-16 Valve and splitting system for multi-dimensional liquid analysis

Country Status (6)

Country Link
US (3) US9239319B2 (xx)
EP (1) EP2689244B1 (xx)
JP (1) JP2014514541A (xx)
CN (2) CN103930778A (xx)
HK (1) HK1200210A1 (xx)
WO (1) WO2012129076A1 (xx)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8621915B2 (en) * 2007-05-29 2014-01-07 Waters Technologies Corp. Apparatus and methods for multidimensional analysis
WO2012129076A1 (en) 2011-03-23 2012-09-27 Idex Health & Science Llc Valve and splitting system for multi-dimensional liquid analysis
WO2014000778A1 (en) * 2012-06-26 2014-01-03 Agilent Technologies, Inc. Fluidic valve with selectively switchable storage paths
US9683975B2 (en) 2014-02-12 2017-06-20 Idex Health & Science Llc Volumetric flow regulation in multi-dimensional liquid analysis systems
WO2015198096A1 (en) 2014-06-25 2015-12-30 Agilent Technologies, Inc. Secondary stage fluid separation device detachably connectable with primary stage fluid separation device
DE102014110865A1 (de) 2014-07-31 2014-12-18 Agilent Technologies, Inc. - A Delaware Corporation - Zwischenspeichern von Probenabschnitten zur artefaktunterdrückenden Fluidverarbeitung
US9816971B2 (en) * 2014-09-08 2017-11-14 Waters Technologies Corporation Controllable injector sample dilution for a liquid chromatography system
EP3798630A1 (en) 2014-10-27 2021-03-31 F. Hoffmann-La Roche AG Systems and methods for two-dimensional rplc-sfc chromatography
US9945762B2 (en) * 2014-12-30 2018-04-17 Agilent Technologies, Inc. Apparatus and method for introducing sample into a separation unit of a chromatography system without disrupting a mobile phase
CN106610435B (zh) * 2015-10-23 2019-11-29 株式会社岛津制作所 自动进样器的控制方法及控制装置
US11371968B2 (en) 2016-05-30 2022-06-28 Agilent Technologies, Inc. Branching off fluidic sample with low influence on source flow path
EP3252463B1 (en) * 2016-05-30 2019-02-20 Agilent Technologies, Inc. (A Delaware Corporation) Branching off fluidic sample with low influence on source flow path
US11009488B2 (en) * 2016-12-08 2021-05-18 Shimadzu Corporation Fluid chromatograph
US10836990B2 (en) 2016-12-23 2020-11-17 Cyberoptics Corporation Sensor interface for single-use containers
CN110412139A (zh) * 2018-04-27 2019-11-05 株式会社岛津制作所 一种分析系统
US11933769B2 (en) * 2018-04-30 2024-03-19 Agilent Technologies, Inc. Multidimensional sample separation with pressure adjustment
US11307181B1 (en) 2018-07-14 2022-04-19 Sielc Technologies Corporation HPLC system with mixed-mode columns for measuring charged analytes in complex mixtures
CN108663461B (zh) * 2018-08-06 2021-03-19 通标标准技术服务(上海)有限公司 一种测定奶粉中维生素d的方法
GB2593061B (en) * 2018-09-25 2022-12-21 Agilent Technologies Inc Two-dimensional fluid separation with push-pull modulation
US11821879B2 (en) * 2019-03-13 2023-11-21 Shimadzu Corporation Autosampler for chromatograph
JP2022534363A (ja) * 2019-05-31 2022-07-29 ジェンザイム・コーポレーション 二次元lc-ms/msシステム
WO2021019496A1 (en) * 2019-08-01 2021-02-04 Agilent Technologies, Inc. Fluid processing with withdraw-transfer modulation
GB2590418B (en) * 2019-12-17 2024-04-10 Agilent Technologies Inc Fluid separation with sampling unit selectively coupling upstream and downstream of separation unit
EP4081795A1 (en) 2019-12-23 2022-11-02 Waters Technologies Corporation Sample metering and injection for liquid chromatography
CN115917310A (zh) * 2020-06-29 2023-04-04 百时美施贵宝公司 用于分析来自生物反应器的样品的自动化系统和方法

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5186431A (en) * 1989-09-22 1993-02-16 Yehuda Tamari Pressure sensitive valves for extracorporeal circuits
DE69120386T2 (de) 1991-01-17 1996-10-31 Lc Packings Nederland Bv Mikrofluss-Prozessor
US5346622A (en) * 1993-03-04 1994-09-13 Hewlett-Packard Company Hydrocarbon class separation and quantitation by split column effluent analysis
EP0686848A1 (en) 1994-05-09 1995-12-13 Shiseido Company Limited Liquid chromatograph having a micro and semi-micro column
JP3737516B2 (ja) 1995-06-26 2006-01-18 パーセプティブ バイオシステムズ,インコーポレーテッド 高速自動化連続流、多次元分子選別および分析
US5607581A (en) * 1995-10-31 1997-03-04 Systec, Inc. Debubbling and priming system for chromotography
US6139734A (en) * 1997-10-20 2000-10-31 University Of Virginia Patent Foundation Apparatus for structural characterization of biological moieties through HPLC separation
JP3575663B2 (ja) * 1998-03-13 2004-10-13 エーザイ株式会社 自動分析装置
US6855258B2 (en) 1999-04-02 2005-02-15 Symyx Technologies, Inc. Methods for characterization of polymers using multi-dimensional liquid chromatography with parallel second-dimension sampling
US6289914B1 (en) 2000-08-16 2001-09-18 Novartis Ag Microflow splitter
US6858435B2 (en) 2000-10-03 2005-02-22 Dionex Corporation Method and system for peak parking in liquid chromatography-mass spectrometer (LC-MS) analysis
US6989129B2 (en) * 2001-04-05 2006-01-24 The President And Fellows Of Harvard College Automated capillary liquid chromatography small volume analysis system
US20020189947A1 (en) 2001-06-13 2002-12-19 Eksigent Technologies Llp Electroosmotic flow controller
WO2003021251A1 (en) * 2001-08-28 2003-03-13 Symyx Technologies, Inc. Methods for characterization of polymers using multi-dimentional liquid chromatography
WO2003044526A1 (en) * 2001-11-16 2003-05-30 Waters Investments Limited Parallel concentration, desalting and deposition onto maldi targets
JP2003207494A (ja) * 2002-01-11 2003-07-25 Sumitomo Chem Co Ltd クロマトグラフ装置用分流装置
WO2003072255A1 (en) 2002-02-23 2003-09-04 Nanostream, Inc. Microfluidic multi-splitter
US6802967B2 (en) 2002-03-06 2004-10-12 Shimadzu Corporation Multi-dimension liquid chromatography separation system
WO2003095978A2 (en) 2002-05-09 2003-11-20 Surromed, Inc. Methods for time-alignment of liquid chromatography-mass spectrometry data
JP2005147756A (ja) 2003-11-12 2005-06-09 Shimadzu Corp 送液ポンプ装置
DE202005001630U1 (de) * 2004-02-06 2005-06-23 Micromass Uk Ltd. Massenspektrometer
EP1721155B1 (en) 2004-03-04 2015-05-06 PerkinElmer Health Sciences, Inc. Systems for characterizing a sorbent tube
US20050214130A1 (en) * 2004-03-29 2005-09-29 Yang Frank J Multidimensional pump apparatus and method for fully automated complex mixtures separation, identification, and quantification
JP4589393B2 (ja) 2004-07-26 2010-12-01 パーキンエルマー・ヘルス・サイエンシズ・インコーポレーテッド クロマトグラフカラムを通して流れる流体を循環するためのシステム
US7507337B2 (en) 2004-09-03 2009-03-24 Symyx Technologies, Inc. System and method for rapid chromatography with fluid temperature and mobile phase composition control
US7377935B2 (en) * 2004-09-24 2008-05-27 Life Recovery Systems Hd, Llc Apparatus for altering the body temperature of a patient
WO2006042365A1 (en) 2004-10-18 2006-04-27 Varian Australia Pty Ltd Liquid chromatography apparatus
US20060157647A1 (en) 2005-01-18 2006-07-20 Becton, Dickinson And Company Multidimensional liquid chromatography/spectrometry
JP4709629B2 (ja) 2005-10-19 2011-06-22 株式会社日立ハイテクノロジーズ ポンプ装置
US7624626B2 (en) 2005-11-17 2009-12-01 Aim Research Co. Dynamic flow liquid chromatography
JP4790435B2 (ja) 2006-02-03 2011-10-12 株式会社日立ハイテクノロジーズ 3次元液体クロマトグラフィ
CA2657064C (en) * 2006-07-19 2014-09-23 Noab Biodiscoveries Inc. Method and device to extract components contained in a fluid
CN101169393A (zh) * 2006-10-25 2008-04-30 中国科学院大连化学物理研究所 一种二维阵列液相色谱-质谱联用方法
WO2008118808A1 (en) * 2007-03-23 2008-10-02 Advion Bioscience, Inc. Liquid chromatography-mass spectrometry
US7900504B2 (en) * 2007-03-26 2011-03-08 M-I Llc High pressure fracture tester
US8621915B2 (en) 2007-05-29 2014-01-07 Waters Technologies Corp. Apparatus and methods for multidimensional analysis
CN103630639A (zh) * 2007-12-05 2014-03-12 全技术联合公司 用于分析样本和收集样本流份的方法和装置
CN101469015B (zh) * 2007-12-28 2011-08-24 中国科学院大连化学物理研究所 一种二维毛细管电泳装置及其应用
CN101762666A (zh) * 2008-12-26 2010-06-30 上海通微分析技术有限公司 一种多维色谱联用分离装置
WO2012129076A1 (en) 2011-03-23 2012-09-27 Idex Health & Science Llc Valve and splitting system for multi-dimensional liquid analysis

Also Published As

Publication number Publication date
US9239319B2 (en) 2016-01-19
US20160131619A1 (en) 2016-05-12
CN103930778A (zh) 2014-07-16
JP2014514541A (ja) 2014-06-19
EP2689244A4 (en) 2014-09-24
EP2689244A1 (en) 2014-01-29
US11692980B2 (en) 2023-07-04
EP2689244B1 (en) 2020-06-17
US20120240666A1 (en) 2012-09-27
US10429361B2 (en) 2019-10-01
US20200025726A1 (en) 2020-01-23
WO2012129076A1 (en) 2012-09-27
CN108956788A (zh) 2018-12-07
CN108956788B (zh) 2022-08-02

Similar Documents

Publication Publication Date Title
HK1200210A1 (en) Valve and splitting system for multi-dimensional liquid analysis
IL257714B (en) Systems and methods for the analysis of multiple analytes
SG10201602113TA (en) Systems And Methods For Biological Analysis
EP2909514A4 (en) VALVE SYSTEM AND METHOD
GB201616219D0 (en) Methods and systems for detecting biological components
EP3080300A4 (en) Systems and methods for biological analysis and computation
EP2856120A4 (en) SYSTEM AND METHOD FOR THE ANALYSIS OF BIOLOGICAL LIQUIDS
SG11201405785WA (en) Systems and methods for biological analysis
EP2714935A4 (en) SYSTEMS AND METHODS FOR GENETIC AND BIOLOGICAL ANALYSIS
SG11201401919TA (en) Optical systems and methods for biological analysis
EP2699655A4 (en) SYSTEMS AND METHODS FOR FRACTIONING VINASSE
EP2705419A4 (en) DATABASE SYSTEM AND METHOD THEREFOR
EP2740026A4 (en) METHOD AND SYSTEMS FOR BIOLOGICAL DATA ANALYSIS
EP2852344A4 (en) SYSTEMS AND METHODS FOR TRANSDUCER ACTIVATION
EP2702508A4 (en) GENERIC SYSTEM OF LANGUAGE ANALYSIS AND TRANSFORMATION
EP2684031A4 (en) SYSTEM AND METHOD FOR FLUORESCENT AND ABSORPTION FORCE ANALYSIS
EP2891881A4 (en) MULTIDIMENSIONAL LIQUID CHROMATOGRAPHIC SEPARATION SYSTEM AND SEPARATING PROCESS FOR PROTEIN SEPARATION
EP2761560A4 (en) SYSTEMS AND METHOD FOR CLASSIFYING WINE
SG11201500600VA (en) Systems and methods for analyzing microbiological substances
IL228413A0 (en) Methods and systems for communication
HK1204823A1 (en) Liquid sampling valve
HK1198223A1 (en) System and method for personal stress analysis
EP2909346A4 (en) PROCESS AND SYSTEM FOR SAMPLE PREPARATION
HK1200498A1 (en) Systems, apparatus and methods for biochemical analysis
EP2705135A4 (en) SYSTEMS AND METHODS FOR ANALYZING BASOPHILES