HK1199727A1 - 抗細菌的哌啶基取代的 -二氫- 萘啶酮 - Google Patents
抗細菌的哌啶基取代的 -二氫- 萘啶酮Info
- Publication number
- HK1199727A1 HK1199727A1 HK15100116.2A HK15100116A HK1199727A1 HK 1199727 A1 HK1199727 A1 HK 1199727A1 HK 15100116 A HK15100116 A HK 15100116A HK 1199727 A1 HK1199727 A1 HK 1199727A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- naphthyridinones
- dihydro
- antibacterial
- piperidinyl substituted
- piperidinyl
- Prior art date
Links
- KQJVDEBWHJRJBT-UHFFFAOYSA-N 3,4-dihydro-1h-1,8-naphthyridin-2-one Chemical class C1=CN=C2NC(=O)CCC2=C1 KQJVDEBWHJRJBT-UHFFFAOYSA-N 0.000 title 1
- 230000000844 anti-bacterial effect Effects 0.000 title 1
- 125000003386 piperidinyl group Chemical group 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11177116 | 2011-08-10 | ||
| PCT/EP2012/065730 WO2013021052A1 (en) | 2011-08-10 | 2012-08-10 | Antibacterial piperidinyl substituted 3,4-dihydro-1h-[1,8]naphthyridinones |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1199727A1 true HK1199727A1 (zh) | 2015-07-17 |
Family
ID=46724388
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK15100116.2A HK1199727A1 (zh) | 2011-08-10 | 2015-01-07 | 抗細菌的哌啶基取代的 -二氫- 萘啶酮 |
| HK16111928.6A HK1223614A1 (zh) | 2011-08-10 | 2016-10-17 | 抗細菌的哌啶基取代的 -二氫- 萘啶酮 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK16111928.6A HK1223614A1 (zh) | 2011-08-10 | 2016-10-17 | 抗細菌的哌啶基取代的 -二氫- 萘啶酮 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US9012634B2 (zh) |
| EP (1) | EP2742047B1 (zh) |
| JP (2) | JP6294822B2 (zh) |
| KR (1) | KR101967174B1 (zh) |
| CN (2) | CN105503869A (zh) |
| AU (1) | AU2012293619B2 (zh) |
| BR (1) | BR112014002958B1 (zh) |
| CA (1) | CA2842531C (zh) |
| EA (1) | EA201490435A1 (zh) |
| ES (1) | ES2881681T3 (zh) |
| HK (2) | HK1199727A1 (zh) |
| MX (1) | MX363478B (zh) |
| WO (1) | WO2013021052A1 (zh) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105503869A (zh) * | 2011-08-10 | 2016-04-20 | 爱尔兰詹森科学公司 | 抗细菌的哌啶基取代的3,4-二氢-1h-[1,8]萘啶酮 |
| JO3611B1 (ar) | 2011-08-10 | 2020-08-27 | Janssen Sciences Ireland Uc | سايكلو بنتا (سي (بيرول 4,3 ثاني هيدرو 1 hمستبدله [8,1] نافثيريدينونات مضادة للجراثيم |
| WO2013080222A1 (en) * | 2011-12-02 | 2013-06-06 | Aurigene Discovery Technologies Limited | Substituted pyridine derivatives as fabi inhibitors |
| US9062075B2 (en) | 2011-12-02 | 2015-06-23 | Aurigene Discovery Technologies Limited | Tetrahydropyridine derivatives as FabI inhibitors |
| WO2014072930A2 (en) * | 2012-11-09 | 2014-05-15 | Aurigene Discovery Technologies Limited | Fused pyridine derivatives as antibacterial agents |
| WO2014195844A1 (en) * | 2013-06-04 | 2014-12-11 | Aurigene Discovery Technologies Limited | TETRAHYDROPYRIDINE DERIVATIVES AS FabI INHIBITORS |
| WO2015071780A1 (en) * | 2013-11-12 | 2015-05-21 | Aurigene Discovery Technologies Limited | Alkylidine substituted heterocyclyl derivatives as anti-bacterial agents |
| LT6177B (lt) | 2014-10-10 | 2015-07-27 | Uab "Biocentras" | Fermentų kompleksų išskyrimas iš steptomyces gougerotii 101, daugiafermentinių biopreparatų ruošimas bei taikymas |
| CN107652226B (zh) * | 2017-11-15 | 2020-03-31 | 上海皓伯化工科技有限公司 | 一种N-Boc-4-哌啶甲醛的制备方法 |
| KR102037494B1 (ko) * | 2017-12-11 | 2019-10-28 | 씨제이헬스케어 주식회사 | 광학활성을 갖는 피페리딘 유도체의 중간체 및 이의 제조방법 |
| KR20190120112A (ko) | 2019-10-08 | 2019-10-23 | 씨제이헬스케어 주식회사 | 광학활성을 갖는 피페리딘 유도체의 중간체 및 이의 제조방법 |
| CN113527220A (zh) * | 2021-07-26 | 2021-10-22 | 京博农化科技有限公司 | 一种脱硫丙硫菌唑异构体的合成方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4215123A (en) | 1979-05-07 | 1980-07-29 | American Home Products Corporation | Antisecretory 4-oxy-3-carboxy or cyano-1,2-dihydro-2-oxo-1,8-naphthyridine derivatives |
| JP4831907B2 (ja) | 1999-10-08 | 2011-12-07 | アフィニアム・ファーマシューティカルズ・インコーポレイテッド | ＦａｂＩ阻害剤 |
| CO5251401A1 (es) | 1999-10-08 | 2003-02-28 | Smithkline Beecham Corp | Inhibidores de fab i |
| CZ302015B6 (cs) | 1999-10-08 | 2010-09-08 | Affinium Pharmaceuticals, Inc. | Inhibitory Fab I |
| ATE420640T1 (de) | 2001-04-06 | 2009-01-15 | Affinium Pharm Inc | Fab-i-inhibitoren |
| SI1828167T1 (sl) * | 2004-06-04 | 2014-12-31 | Debiopharm International Sa Forum "Apres-Demain" | Akrilamidni derivati kot anitibiotična sredstva |
| US7732612B2 (en) | 2004-09-09 | 2010-06-08 | Janssen Pharmaceutica, N.V. | 7-amino alkylidenyl-heterocyclic quinolones and naphthyridones |
| US7973060B2 (en) | 2005-10-13 | 2011-07-05 | Crystalgenomics, Inc. | Fab I inhibitor and process for preparing same |
| EP2054422B1 (en) | 2006-07-20 | 2017-06-14 | Debiopharm International SA | Acrylamide derivatives as fab i inhibitors |
| WO2008098374A1 (en) | 2007-02-16 | 2008-08-21 | Affinium Pharmaceuticals, Inc. | Salts, prodrugs and polymorphs of fab i inhibitors |
| AU2010320963B2 (en) * | 2009-11-18 | 2015-07-09 | Fab Pharma Sas | Novel heterocyclic acrylamides and their use as pharmaceuticals |
| NZ605440A (en) | 2010-06-10 | 2014-05-30 | Abbvie Bahamas Ltd | Solid compositions comprising an hcv inhibitor |
| CN105503869A (zh) * | 2011-08-10 | 2016-04-20 | 爱尔兰詹森科学公司 | 抗细菌的哌啶基取代的3,4-二氢-1h-[1,8]萘啶酮 |
| JO3611B1 (ar) | 2011-08-10 | 2020-08-27 | Janssen Sciences Ireland Uc | سايكلو بنتا (سي (بيرول 4,3 ثاني هيدرو 1 hمستبدله [8,1] نافثيريدينونات مضادة للجراثيم |
-
2012
- 2012-08-10 CN CN201610095183.9A patent/CN105503869A/zh active Pending
- 2012-08-10 CN CN201280039121.6A patent/CN103917540B/zh active Active
- 2012-08-10 EP EP12750575.8A patent/EP2742047B1/en active Active
- 2012-08-10 EA EA201490435A patent/EA201490435A1/ru unknown
- 2012-08-10 CA CA2842531A patent/CA2842531C/en active Active
- 2012-08-10 ES ES12750575T patent/ES2881681T3/es active Active
- 2012-08-10 BR BR112014002958-0A patent/BR112014002958B1/pt not_active IP Right Cessation
- 2012-08-10 MX MX2014001599A patent/MX363478B/es unknown
- 2012-08-10 US US14/237,851 patent/US9012634B2/en active Active
- 2012-08-10 KR KR1020147004176A patent/KR101967174B1/ko active IP Right Grant
- 2012-08-10 JP JP2014524409A patent/JP6294822B2/ja active Active
- 2012-08-10 WO PCT/EP2012/065730 patent/WO2013021052A1/en active Application Filing
- 2012-08-10 AU AU2012293619A patent/AU2012293619B2/en not_active Ceased
-
2015
- 2015-01-07 HK HK15100116.2A patent/HK1199727A1/zh not_active IP Right Cessation
- 2015-02-17 US US14/624,452 patent/US9598407B2/en active Active
-
2016
- 2016-10-17 HK HK16111928.6A patent/HK1223614A1/zh unknown
-
2017
- 2017-06-07 JP JP2017112306A patent/JP6552550B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| BR112014002958A2 (pt) | 2017-02-21 |
| CN103917540B (zh) | 2016-03-16 |
| JP2014521715A (ja) | 2014-08-28 |
| ES2881681T3 (es) | 2021-11-30 |
| AU2012293619B2 (en) | 2017-05-04 |
| US9012634B2 (en) | 2015-04-21 |
| US20150158866A1 (en) | 2015-06-11 |
| JP2017222647A (ja) | 2017-12-21 |
| CA2842531A1 (en) | 2013-02-14 |
| CA2842531C (en) | 2019-07-16 |
| JP6552550B2 (ja) | 2019-07-31 |
| US9598407B2 (en) | 2017-03-21 |
| EP2742047B1 (en) | 2021-05-12 |
| MX2014001599A (es) | 2014-04-25 |
| AU2012293619A1 (en) | 2014-02-06 |
| HK1223614A1 (zh) | 2017-08-04 |
| WO2013021052A1 (en) | 2013-02-14 |
| KR101967174B1 (ko) | 2019-04-09 |
| BR112014002958B1 (pt) | 2020-10-06 |
| CN105503869A (zh) | 2016-04-20 |
| JP6294822B2 (ja) | 2018-03-14 |
| MX363478B (es) | 2019-03-22 |
| US20140163038A1 (en) | 2014-06-12 |
| CN103917540A (zh) | 2014-07-09 |
| EP2742047A1 (en) | 2014-06-18 |
| EA201490435A1 (ru) | 2014-06-30 |
| KR20140079759A (ko) | 2014-06-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20230815 |