HK1199056A1 - 灌流式生物反應器系統及操作其的方法 - Google Patents

灌流式生物反應器系統及操作其的方法

Info

Publication number
HK1199056A1
HK1199056A1 HK14112683.1A HK14112683A HK1199056A1 HK 1199056 A1 HK1199056 A1 HK 1199056A1 HK 14112683 A HK14112683 A HK 14112683A HK 1199056 A1 HK1199056 A1 HK 1199056A1
Authority
HK
Hong Kong
Prior art keywords
operating
methods
same
perfusion bioreactor
bioreactor systems
Prior art date
Application number
HK14112683.1A
Other languages
English (en)
Inventor
Medhi Saghari
Ricaredo Matanguihan
Chetan Goudar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of HK1199056A1 publication Critical patent/HK1199056A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10—Perfusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C12M33/22—Settling tanks; Sedimentation by gravity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/02—Separating microorganisms from the culture medium; Concentration of biomass
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/10—Separation or concentration of fermentation products

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
HK14112683.1A 2012-01-18 2014-12-18 灌流式生物反應器系統及操作其的方法 HK1199056A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261587940P 2012-01-18 2012-01-18
PCT/US2013/021533 WO2013109520A1 (en) 2012-01-18 2013-01-15 Perfusion bioreactor systems and methods of operating the same

Publications (1)

Publication Number Publication Date
HK1199056A1 true HK1199056A1 (zh) 2015-06-19

Family

ID=47605793

Family Applications (1)

Application Number Title Priority Date Filing Date
HK14112683.1A HK1199056A1 (zh) 2012-01-18 2014-12-18 灌流式生物反應器系統及操作其的方法

Country Status (6)

Country Link
EP (1) EP2804943A1 (zh)
JP (1) JP6227562B2 (zh)
CN (1) CN104160013B (zh)
CA (1) CA2861270C (zh)
HK (1) HK1199056A1 (zh)
WO (1) WO2013109520A1 (zh)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3047013B1 (en) * 2013-09-16 2021-08-18 Genzyme Corporation Methods and systems for processing a cell culture
JP6896242B2 (ja) * 2013-12-30 2021-06-30 グローバル・ライフ・サイエンシズ・ソリューションズ・ユーエスエー・エルエルシー 細胞培養のための装置
JP2017527299A (ja) * 2014-09-17 2017-09-21 マサチューセッツ インスティテュート オブ テクノロジー 灌流バイオリアクター細胞保持のためのマイクロ流体システム及び方法
US9944894B2 (en) 2015-01-16 2018-04-17 General Electric Company Pluripotent stem cell expansion and passage using a rocking platform bioreactor
JP6943449B2 (ja) * 2016-03-21 2021-09-29 グローバル・ライフ・サイエンシズ・ソリューションズ・ユーエスエー・エルエルシー 撹拌タンクバイオリアクタを用いた多能性幹細胞の増殖および継代
CN107541464B (zh) * 2017-10-31 2021-04-30 山东亦度生物技术有限公司 增强型的细胞微载体灌流培养的截留方法
EP3797149A1 (en) * 2018-05-22 2021-03-31 Nantkwest, Inc. Methods and systems for cell bed formation during bioprocessing
JP7087704B2 (ja) * 2018-06-13 2022-06-21 株式会社Ihi 細胞培養システム及び細胞培養方法
US11028359B2 (en) 2018-09-11 2021-06-08 Global Life Sciences Solutions Usa Llc Separation devices, associated methods, and systems
GB201904083D0 (en) * 2019-03-25 2019-05-08 Ge Healthcare Bio Sciences Ab A bioreactor system
EP3835403A1 (en) 2019-12-11 2021-06-16 Sartorius Stedim Biotech GmbH Automated medium exchange strategy for suspension cells
JP7406205B2 (ja) * 2020-03-24 2023-12-27 横河電機株式会社 メタン生成装置
WO2024092004A1 (en) * 2022-10-26 2024-05-02 National Resilience, Inc. Bioreactor systems and methods of operating same

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05153973A (ja) * 1991-12-03 1993-06-22 Hitachi Ltd 細胞培養方法及び装置
US6338964B1 (en) 1999-05-07 2002-01-15 Bayer Corporation Process and medium for mammalian cell culture under low dissolved carbon dioxide concentration
CN1112442C (zh) * 2000-06-14 2003-06-25 华东理工大学 细胞灌注培养过程中的细胞截留分离方法及其装置
PT1451290E (pt) * 2001-08-31 2011-03-09 Bayer Schering Pharma Ag Uma unidade e um processo para levar a cabo a fermentação com elevada densidade celular
ES2570006T3 (es) 2004-09-30 2016-05-13 Bayer Healthcare Llc Dispositivos y métodos de preparación continua integrada de moléculas biológicas
WO2007071072A1 (en) * 2005-12-22 2007-06-28 Corporation De L'ecole Polytechnique De Montreal High-rate perfusion bioreactor
US8512566B2 (en) * 2009-12-11 2013-08-20 General Electric Company Disposable fluid path systems and methods for processing complex biological materials

Also Published As

Publication number Publication date
EP2804943A1 (en) 2014-11-26
JP6227562B2 (ja) 2017-11-08
JP2015503929A (ja) 2015-02-05
CA2861270A1 (en) 2013-07-25
CN104160013B (zh) 2017-07-28
WO2013109520A1 (en) 2013-07-25
CN104160013A (zh) 2014-11-19
CA2861270C (en) 2021-08-03

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